imidafenacin and Spinal-Cord-Injuries

A retrospective study.. To investigate the effect of imidafenacin on the urodynamic parameters of patients with indwelling bladder catheters due to spinal cord injury (SCI).. Spinal center (Tokyo, Japan).. Imidafenacin was prescribed to 34 patients with SCI who had a low cystometric volume and/or detrusor compliance according to a urodynamic study. A low cystometric volume and detrusor compliance were defined as <200 ml and <20 ml cm. Fifteen patients took 0.2 mg of imidafenacin daily, and 19 received 0.4 mg of imidafenacin daily. Imidafenacin increased the cystometric volume from 246.0 to 321.5 ml (median, P=0.002), detrusor compliance from 6.67 ml cm. Imidafenacin is a safe drug that may improve the urodynamic parameters of patients with SCI, and it possibly alleviates bladder complications.

Topics: Aged; Female; Humans; Imidazoles; Male; Middle Aged; Retrospective Studies; Spinal Cord Injuries; Treatment Outcome; Urinary Bladder; Urinary Catheterization; Urinary Catheters; Urodynamics