Page last updated: 2024-10-29

imetit and Rhinitis, Allergic, Perennial

imetit has been researched along with Rhinitis, Allergic, Perennial in 3 studies

imetit: structure given in first source
imetit : An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.

Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yokota, E1
Kuyama, S1
Sugimoto, Y1
Ogawa, M1
Kamei, C1
Yang, X1
Sun, G1
Xu, X1
Li, P1
Liu, W2
Sun, GM1
Yang, XD1
Xu, XG1
Li, PH1
Pan, LJ1

Other Studies

3 other studies available for imetit and Rhinitis, Allergic, Perennial

ArticleYear
Participation of histamine H3 receptors in experimental allergic rhinitis of mice.
    Journal of pharmacological sciences, 2008, Volume: 108, Issue:2

    Topics: Animals; Anti-Allergic Agents; Cetirizine; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Respo

2008
[Effect of H3R agonist, IMETIT on allergic rhinitis in guinea pigs].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2010, Volume: 24, Issue:12

    Topics: Animals; Female; Guinea Pigs; Imidazoles; Male; Receptors, Histamine H3; Receptors, Neurokinin-1; Rh

2010
[Substance P and its receptors are involved in the effect of histamine H3 receptor agonist, IMETIT on nasal allergic symptoms in guinea pigs].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2010, Volume: 45, Issue:6

    Topics: Animals; Female; Guinea Pigs; Histamine Agonists; Imidazoles; Loratadine; Male; Nasal Mucosa; Recept

2010