imetit has been researched along with Obesity in 2 studies
imetit: structure given in first source
imetit : An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results showed that thioperamide, an H3R inverse agonist, increases, whereas imetit, an H3R agonist, decreases appetite and body weight in diet-induced obese (DiO) WT mice." | 3.73 | Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus. ( Chen, AS; Chen, HY; Ishihara, A; Kanatani, A; Kotani, H; Macneil, DJ; Miyamoto, Y; Shimamura, K; Takahashi, K; Tokita, S; Yoshimoto, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jethwa, PH | 1 |
| Barrett, P | 1 |
| Turnbull, Y | 1 |
| Enright, RA | 1 |
| Warner, A | 1 |
| Murphy, M | 1 |
| Ebling, FJ | 1 |
| Yoshimoto, R | 1 |
| Miyamoto, Y | 1 |
| Shimamura, K | 1 |
| Ishihara, A | 1 |
| Takahashi, K | 1 |
| Kotani, H | 1 |
| Chen, AS | 1 |
| Chen, HY | 1 |
| Macneil, DJ | 1 |
| Kanatani, A | 1 |
| Tokita, S | 1 |
2 other studies available for imetit and Obesity
| Article | Year |
|---|---|
The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.
Topics: Animals; Body Temperature; Cell Line, Transformed; Cricetinae; Disease Models, Animal; Eating; Hista | 2009 |
Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus.
Topics: Animals; Appetite; Body Weight; Diabetes Mellitus; Histamine Agonists; Imidazoles; Insulin; Leptin; | 2006 |