imetit has been researched along with Diabetes Mellitus in 1 studies
imetit: structure given in first source
imetit : An imidothiocarbamic ester that consists of isothiourea in which the thiol hydrogen is substituted by a 2-(imidazol-4-yl)ethyl group. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results showed that thioperamide, an H3R inverse agonist, increases, whereas imetit, an H3R agonist, decreases appetite and body weight in diet-induced obese (DiO) WT mice." | 3.73 | Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus. ( Chen, AS; Chen, HY; Ishihara, A; Kanatani, A; Kotani, H; Macneil, DJ; Miyamoto, Y; Shimamura, K; Takahashi, K; Tokita, S; Yoshimoto, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshimoto, R | 1 |
| Miyamoto, Y | 1 |
| Shimamura, K | 1 |
| Ishihara, A | 1 |
| Takahashi, K | 1 |
| Kotani, H | 1 |
| Chen, AS | 1 |
| Chen, HY | 1 |
| Macneil, DJ | 1 |
| Kanatani, A | 1 |
| Tokita, S | 1 |
1 other study available for imetit and Diabetes Mellitus
| Article | Year |
|---|---|
Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus.
Topics: Animals; Appetite; Body Weight; Diabetes Mellitus; Histamine Agonists; Imidazoles; Insulin; Leptin; | 2006 |