imet-98-69 and Vaccinia

imet-98-69 has been researched along with Vaccinia* in 1 studies

Other Studies

1 other study(ies) available for imet-98-69 and Vaccinia

ArticleYear
Antiviral effect of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4,5-diphenyl-oxyazolyl-(2)]hydrazone (IMET 98/69) in mice.
    Acta virologica, 1979, Volume: 23, Issue:6

    The potential in vivo antiviral activity of 3-[bis-(2-hydroxyethyl)-amino]-acetophenone-[4,5-diphenyl-oxazolyl-(2)]-hydrazone (IMET 98/69) was evaluated on model infections in mice. Animals treated subcutaneously (s.c.) with 1 mmole of the drug per kg body weight once daily for five days were significantly protected against a lethal infection with cardioviruses, Semliki forest virus and vaccinia virus. In influenza A and B virus models no antiviral activity was observed either after s.c. or oral treatment.

    Topics: Administration, Oral; Animals; Antiviral Agents; Arbovirus Infections; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyocarditis virus; Enterovirus Infections; Female; Injections, Subcutaneous; Male; Mice; Orthomyxoviridae Infections; Oxazoles; RNA Viruses; Semliki forest virus; Vaccinia; Virus Diseases

1979
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