imatinib mesylate has been researched along with Eosinophilia, Tropical in 87 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 39 (44.83) | 29.6817 |
2010's | 35 (40.23) | 24.3611 |
2020's | 13 (14.94) | 2.80 |
Authors | Studies |
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Brunner, AM; Dal Cin, P; De Angelo, DJ; Dias-Santagata, D; Iafrate, AJ; Le, LP; Lennerz, JK; Luskin, MR; Marble, HD; Mueller, SB; Nardi, V; Stone, RM; Weinstock, MJ | 1 |
Fujii, T; Kitahara, S; Kobayashi, S; Matsui, T; Matsunaga, T; Ohno, N; Sahara, N; Sakamoto, N | 1 |
Abermil, N; Badaoui, B; Bontoux, C; Crickx, E; Dubois, S; Favre, L; Guermouche, H; Michel, M; Pécriaux, A; Poullot, E; Quang, VT; Roy, L; Sloma, I; Tarfi, S; Wang, L; Xuan, JV | 1 |
Gotlib, J | 1 |
Al-Qattan, Y; Ali, S; AlShemmari, S; Awny, W; Hamadah, A; Pinto, K | 1 |
Coltro, G; Santi, R | 1 |
Adam, M; Bröckelmann, PJ; Wienemann, H | 1 |
Cross, NCP; Fabarius, A; Haferlach, T; Hochhaus, A; Hofmann, WK; Jawhar, M; Metzgeroth, G; Naumann, N; Reiter, A; Schwaab, J | 1 |
Dal Cin, P; Ebert, BL; Grinshpun, DE; Hobbs, GS; Iafrate, AJ; Jan, M; Nardi, V; Sykes, DB; Villalba, JA | 1 |
Chen, Y; Cheng, Z; Luo, Y; Peng, H; Wang, Y; Xu, Y; Zhang, G; Zhang, Y | 1 |
Goodarzi, H; Novoa, R; Teng, JMC; Wang, J; Wu, TT | 1 |
Barkoh, BA; Bueso-Ramos, CE; Chen, W; Fang, H; Futreal, A; Gupta, SK; Jain, N; Khoury, JD; Loghavi, S; Luthra, R; Mao, X; Medeiros, LJ; Patel, KP; Routbort, M; Tang, G; Wang, SA; Yang, RK; Zhang, J | 1 |
Cai, P; Chen, S; Lu, Q; Ma, L; Ruan, C; Wang, M; Wang, Z; Xu, X; Zeng, Z; Zhang, L | 1 |
Baer, MR; Hoppman, NL; Kotiah, SD; Sawhney, S; Singh, ZN; Zou, YS | 1 |
Kalhagen, L; Leighton, L; McGrath, K; Stein, B | 1 |
Baurmann, H; Casper, J; Cross, NCP; Dang, TA; Dietze, L; Döhner, K; Fabarius, A; Haferlach, C; Haferlach, T; Hänel, A; Hochhaus, A; Hofmann, WK; Jawhar, M; Lathan, B; Link, H; Lotfi, S; Maywald, O; Metzgeroth, G; Mielke, S; Müller, L; Naumann, N; Panse, J; Platzbecker, U; Prümmer, O; Reiter, A; Schwaab, J; Thomssen, H; Töpelt, K; Vieler, T | 1 |
Hawes, V; Lobo, RH; Sasapu, A; Socola, F | 1 |
Li, Y; Tu, S; Wang, Y; Wu, Q; Xia, L; Yang, J; Zhang, M; Zhao, M | 1 |
Aouinti, I; Badri, T; Charfi, O; Elaidli, S; Kastalli, S; Lakhoua, G; Zaïem, A; Zgolli, F | 1 |
Baker, A; Scordino, T; Srinivasan, A | 1 |
Fukazawa, M; Hatanaka, Y; Iseki, T; Ishizuka, Y; Mimura, N; Mitsukawa, S; Muto, T; Nakaseko, C; Ohwada, C; Oshima-Hasegawa, N; Ozawa, S; Sakaida, E; Takeda, Y; Takeuchi, M; Tsukamoto, S; Yamazaki, M | 1 |
Cross, NC; Fabarius, A; Gosenca, D; Haferlach, C; Hochhaus, A; Hofmann, WK; Metzgeroth, G; Reiter, A; Schwaab, J | 1 |
Fancher, KM; Green, MR; Newton, MD | 1 |
Garcia-Manero, G; Khoury, JD; Loghavi, S; Shah, S | 1 |
Aguiar, RC; Apperley, JF; Burbury, K; Cheah, CY; Cross, NC; Dunbar, CE; Forrest, D; Gardembas, M; Genet, P; Gimelfarb, A; Huguet, F; Ito, S; Odenike, O; Patton, N; Pitini, V; Ross, DM; Rousselot, P; Seymour, JF; Smith, G | 1 |
Cross, NC; Erben, P; Fabarius, A; Gosenca, D; Haferlach, C; Haferlach, T; Hofmann, WK; Kellert, B; Kneba, M; Metzgeroth, G; Reiter, A; Scheid, C; Schwaab, J; Seifarth, W; Töpelt, K | 1 |
Kristensen, TK; Møller, MB; Rathe, M; Schomerus, E; Wehner, PS | 1 |
Ali, SM; Campregher, PV; Chalmers, ZR; Chmielecki, J; Elvin, JA; Erlich, R; Frampton, GM; Hermann, R; Miles, CR; Miller, VA; Ohgami, RS; Palma, NA; Ross, JS; Stephens, PJ; Vergilio, JA; Yelensky, R | 1 |
Bogdanovic, A; Elezovic, I; Gotic, M; Jankovic, G; Lekovic, D; Perunicic-Jovanovic, M | 1 |
Jeon, J; Koh, YI; Ryang, DW; Won, EJ | 1 |
Cross, NC; Dang, TA; Dietz, CT; Fabarius, A; Gärtner, M; Göhring, G; Haferlach, C; Hofmann, WK; Jawhar, M; Lotfi, S; Metzgeroth, G; Naumann, N; Reiter, A; Schlegelberger, B; Schnittger, S; Schwaab, J | 1 |
Feng, S; Han, M; He, Y; Liu, Q; Shi, Y; Yang, D; Zhang, R | 1 |
Barraco, D; Elala, Y; Lasho, T; Pardanani, A; Patnaik, M; Tefferi, A | 1 |
Chelysheva, EY; Galstyan, GM; Khuazheva, NK; Kovrigina, AM; Nemchenko, IS; Savchenko, VG; Turkina, AG | 1 |
Bedwell, C; Greystoke, B; McGregor, AK; Oakes, R; Wood, K | 1 |
Abdelmalek, C; Andrei, M; Bandarchuk, A; Gotlieb, V; Kundra, A; Wang, JC | 1 |
Cross, NC; Erben, P; Gosenca, D; Haferlach, C; Hänel, A; Hochhaus, A; Metzgeroth, G; Reiter, A; Walz, C | 1 |
de Revel, T; Fagot, T; Konopacki, J; Malfuson, JV; Mangouka, L; Souleau, B | 1 |
Atallah, E; Bredeson, C; Bryke, C; Divgi, A; Kroft, SH; Nand, R | 1 |
Di, YW; Liu, YH; Zhuang, HG | 1 |
Jotterand, M; Muehlematter, D; Rausch, T; Spertini, O; Stalder, M; Védy, D | 1 |
Liu, L; Qin, TJ; Xiao, ZJ; Zhang, Y; Zhou, CL | 1 |
Gotlib, J; Pardanani, A; Tefferi, A | 1 |
Carlsen, NL; Kristensen, TK; Møller, MB; Rathe, M | 1 |
Gau, JP; Hsiao, LT; Liu, CY; Pai, JT; Teng, HW; Tzeng, CH; Wang, JR; Yen, CC | 1 |
Cheung, WY; Ksienski, D | 1 |
Dumon-Gubeno, MC; Figueredo, M; Medioni, LD; Mouroux, J; Naman, H; Nicolle, I; Tarhini, A; Vandenbos, F | 1 |
Abraham, S; Fluchel, M; Hancock, J; Jacobsen, J; Salama, M | 1 |
D'Souza, A; Hanson, CA; Ketterling, RP; Knudson, RA; Pardanani, A; Tefferi, A | 1 |
Alrwas, A; Juneja, HS; Marcos, LA; Mehta, SS; Nguyen, ND; Quesada, JR; Shattuck, BL | 1 |
Bagot, M; Battistella, M; Flageul, B; Galicier, L; Hickman, G; Isvy-Joubert, A; Petit, A | 1 |
Ali, S; Cross, NC; Dickinson, H; Hidalgo-Curtis, C; Jack, A; Score, J; Waghorn, K; Winkelmann, N | 1 |
Anastasi, J; Hossain, NM; Jain, N; McConville, JF; Odenike, O; Steinmetz, JL | 1 |
Apperley, JF; Bain, BJ; Baxter, EJ; Chase, A; Chessells, JM; Colombat, M; Cross, NC; Dearden, CE; Dimitrijevic, S; Gardembas, M; Goldman, JM; Mahon, FX; Marin, D; Melo, JV; Nikolova, Z; Olavarria, E; Russell-Jones, R; Schultheis, B; Silberman, S | 1 |
Schwartz, RS | 1 |
Alo, G; Arrigo, C; Barresi, G; Pitini, V; Righi, M; Teti, D | 1 |
Brockman, SR; Cools, J; Cross, NC; Dewald, GW; Flynn, HC; Gilliland, DG; Ketterling, RP; Li, CY; Pardanani, A; Paternoster, SF; Reeder, TL; Shearer, BM; Tefferi, A | 1 |
Aguiar, RC; Aster, JC; Lee, C; Lopes, LF; Shipp, MA; Velloso, ER; Wilkinson, K | 1 |
Bloomfield, K; Braunschweig, I; Chadburn, A; Darji, J; Gotlib, V; Patel, A | 1 |
Coutré, S; Gotlib, J | 1 |
Bain, B | 1 |
Elliott, MA; Li, CY; Pardanani, A; Tefferi, A | 1 |
Pardanani, A; Tefferi, A | 2 |
Tefferi, A | 2 |
Brockman, SR; Dewald, GW; Flynn, HC; Ho, CL; Ketterling, RP; Lasho, TL; Li, CY; Pardanani, A; Paternoster, SF; Tefferi, A | 1 |
Baxter, EJ; Burgstaller, S; Chase, AJ; Cross, NC; Grand, FH; Kühr, T; Thaler, J; Webersinke, G | 1 |
Borbényi, Z | 1 |
Clément, JF; Contentin, N; Courville, P; Jardin, F; Laquerriere, A; Lehembre, S; Lenain, P; Lenormand, B; Pouplin, S; Tilly, H | 1 |
Butterfield, JH; Camoriano, JK; Dewald, GW; Elliott, MA; Ketterling, RP; Li, CY; Pardanani, A; Patnaik, MM; Tefferi, A; Wolanskyj, AP | 1 |
Boveri, E; Chichino, G; Cilloni, D; Daniela, C; Emanuela, B; Enrico, G; Giovanni, M; Gottardi, E; Guido, C; Martinelli, G; Merante, S; Serena, M; Simona, S; Soverini, S | 1 |
Charlanne, H; Prin, L | 1 |
Robyn, J | 1 |
Bober, G; Grosicki, S; Helbig, G; Hochhaus, A; Holowiecki, J; Krawczyk, M; Reiter, A; Stella-Holowiecka, B; Wojnar, J | 1 |
Pardanani, A; Patnaik, MM; Tefferi, A | 1 |
Gotoh, M; Kawasugi, K; Noguchi, M; Shirafuji, N; Shirasaki, R; Tashiro, H | 1 |
Naithani, R; Panigrahi, I | 1 |
Augustson, B; Cannell, P; Joske, D; Willson, A | 1 |
Campos, L; Cornillon, J; Delabesse, E; Flandrin, P; Mauvieux, L; Morel, S; Nadal, N; Olaru, D | 1 |
Apperley, JF; Burgstaller, S; Chase, A; Cross, NC; Curtis, C; Dang, R; David, M; Gardembas, M; Goldman, JM; Grand, F; Hughes, G; Huguet, F; Lavender, L; Mahon, FX; Massimini, G; McArthur, GA; Melo, J; Nikolova, Z; Rousselot, P; Russell-Jones, RJ; Seymour, JF; Smith, G; Stark, A; Waghorn, K | 1 |
Butterfield, J; Kantarjian, H; Ketterling, R; Pardanani, A; Tefferi, A; Vaklavas, C; Verstovsek, S | 1 |
Aulitzky, WE; Beneke, H; Cross, NC; Del Valle, F; Diecker, F; Döhner, H; Erben, P; Haferlach, C; Haferlach, T; Hehlmann, R; Hochhaus, A; Hodges, E; Metzgeroth, G; Mix, J; Müller, L; Müller, MC; Müller-Hermelink, K; Popp, H; Reiter, A; Schmitz, N; Schnittger, S; Schuld, P; Schulte, C; Score, J; Siebert, R; Walz, C; Whittaker, SJ; Wittkowsky, G | 1 |
Clark, D; Lyall, H; O'Connor, S | 1 |
Kalac, M; Kantarjian, H; Quintás-Cardama, A; Verstovsek, S; Vrhovac, R | 1 |
England, RW; Scranton, SE; Wild, CA | 1 |
Hamano, Y; Isobe, Y; Nitta, H; Oshimi, K; Sasaki, M; Sato, E; Sugimoto, K; Tomomatsu, J | 1 |
16 review(s) available for imatinib mesylate and Eosinophilia, Tropical
Article | Year |
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Available and emerging therapies for bona fide advanced systemic mastocytosis and primary eosinophilic neoplasms.
Topics: Child; Eosinophilia; Humans; Imatinib Mesylate; Mastocytosis; Mastocytosis, Systemic; Myeloproliferative Disorders; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit | 2022 |
Imatinib-Associated Tumor Lysis Syndrome in a Patient With Myeloid Neoplasm With Eosinophilia and PDGFRA Rearrangement: A Case Report and Review of the Literature.
Topics: Antineoplastic Agents; Biomarkers; Bone Marrow; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Leukemia, Myeloid; Protein Kinase Inhibitors; Receptor, Platelet-Derived Growth Factor alpha; Tumor Lysis Syndrome | 2018 |
Off-Target Effects of BCR-ABL and JAK2 Inhibitors.
Topics: Aniline Compounds; Antineoplastic Agents; Carbazoles; Dasatinib; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Furans; Fusion Proteins, bcr-abl; Gastrointestinal Stromal Tumors; Graft vs Host Disease; Harringtonines; Homoharringtonine; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Imidazoles; Janus Kinase 2; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mastocytosis; Myeloproliferative Disorders; Nitriles; Polycythemia Vera; Primary Myelofibrosis; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyrazoles; Pyridazines; Pyrimidines; Quinolines; Scleroderma, Systemic; Smallpox; Thrombocythemia, Essential; Tuberculosis, Multidrug-Resistant | 2016 |
[Treatment of adult acute lymphoblastie leukemia with eosinophilia and abnormality of PDGFRA by autologous hematopoietic stem cell transplantation and imatinib: one case report and literatures review].
Topics: Adult; Eosinophilia; Hematopoietic Stem Cell Transplantation; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptor, Platelet-Derived Growth Factor alpha | 2015 |
PDGFRᵝ-Rearranged Myeloid Neoplasm with Marked Eosinophilia in a 37-Year-Old Man; And a Literature Review.
Topics: Adult; Antineoplastic Agents; Biomarkers, Tumor; Dose-Response Relationship, Drug; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Leukocyte Count; Leukocytosis; Male; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome | 2017 |
Hypereosinophilic syndrome and clonal eosinophilia: point-of-care diagnostic algorithm and treatment update.
Topics: Alemtuzumab; Algorithms; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Benzamides; Causality; Decision Trees; Diagnosis, Differential; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Mastocytosis; mRNA Cleavage and Polyadenylation Factors; Mutation; Myelodysplastic Syndromes; Piperazines; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Platelet-Derived Growth Factor | 2010 |
Eosinophilic variant of chronic myeloid leukemia with vascular complications.
Topics: Adult; Anticoagulants; Antineoplastic Agents; Benzamides; Bone Marrow; Diagnostic Errors; Eosinophilia; Fingers; Gangrene; Humans; Imatinib Mesylate; Leg; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Pain; Piperazines; Pyrimidines; Radiography; Vasculitis; Vitamins | 2003 |
Targeted treatment of hypereosinophilic syndromes and chronic eosinophilic leukemias with imatinib mesylate.
Topics: Animals; Benzamides; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Substrate Specificity | 2004 |
Imatinib therapy for hypereosinophilic syndrome and eosinophilia-associated myeloproliferative disorders.
Topics: Benzamides; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Mutation; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome | 2004 |
Imatinib therapy in clonal eosinophilic disorders, including systemic mastocytosis.
Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; DNA Mutational Analysis; Eosinophilia; Humans; Imatinib Mesylate; Mastocytosis, Systemic; Piperazines; Pyrimidines; Receptors, Platelet-Derived Growth Factor | 2004 |
Blood eosinophilia: a new paradigm in disease classification, diagnosis, and treatment.
Topics: Benzamides; Eosinophilia; Humans; Imatinib Mesylate; Piperazines; Protein Kinase Inhibitors; Pyrimidines | 2005 |
[Disorders with eosinophilia, treatment of hypereosinophilic syndrome].
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Decision Trees; Eosinophilia; Glucocorticoids; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesylate; Interferon-alpha; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha | 2005 |
[Treatment of hypereosinophilia].
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Benzamides; Chronic Disease; Cyclosporins; Drug Resistance; Eosinophilia; Glucocorticoids; Humans; Hydroxyurea; Imatinib Mesylate; Immunologic Factors; Immunosuppressive Agents; Interferon-alpha; Myeloproliferative Disorders; Parasitic Diseases; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Recurrence; Time Factors | 2006 |
Eosinophilia: secondary, clonal and idiopathic.
Topics: Benzamides; Bone Marrow; Chromosome Aberrations; Cytokines; Eosinophilia; Gene Rearrangement; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Parasitic Diseases; Piperazines; Protein Kinase Inhibitors; Pulmonary Eosinophilia; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta | 2006 |
Imatinib mesylate: A designer drug.
Topics: Benzamides; Eosinophilia; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines | 2006 |
A critical appraisal of conventional and investigational drug therapy in patients with hypereosinophilic syndrome and clonal eosinophilia.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Benzamides; Clone Cells; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Treatment Outcome | 2007 |
5 trial(s) available for imatinib mesylate and Eosinophilia, Tropical
Article | Year |
---|---|
Imatinib in myeloid/lymphoid neoplasms with eosinophilia and rearrangement of PDGFRB in chronic or blast phase.
Topics: Abnormal Karyotype; Adult; Aged; Aged, 80 and over; Blast Crisis; Disease-Free Survival; Eosinophilia; Female; Follow-Up Studies; Gene Rearrangement; Hematologic Neoplasms; Humans; Imatinib Mesylate; Male; Middle Aged; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Sex Factors; Survival Rate | 2017 |
[The efficacy of imatinib mesylate for patients with myeloproliferative neoplasm (MPN) with eosinophilia].
Topics: Adult; Aged; Benzamides; Eosinophilia; Follow-Up Studies; Humans; Imatinib Mesylate; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome; Young Adult | 2009 |
A novel pathogenetic mutation in clonal eosinophilia.
Topics: Benzamides; Cell Division; Cell Line, Transformed; Chromosome Deletion; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 4; Clone Cells; DNA Mutational Analysis; Eosinophilia; Humans; Imatinib Mesylate; Inhibitory Concentration 50; mRNA Cleavage and Polyadenylation Factors; Mutation; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Remission Induction; Translocation, Genetic | 2004 |
Molecular analysis of chronic eosinophilic leukemia with t(4;10) showing good response to imatinib mesylate.
Topics: Adult; Asian People; Benzamides; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 4; Chronic Disease; Enzyme Activation; Eosinophilia; Follow-Up Studies; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukocyte Count; Male; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Time Factors; Translocation, Genetic | 2006 |
Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma.
Topics: Acute Disease; Adult; Aged; Benzamides; Disease-Free Survival; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myeloid; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Nucleophosmin; Oncogene Proteins, Fusion; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein-Tyrosine Kinases; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Remission Induction | 2007 |
66 other study(ies) available for imatinib mesylate and Eosinophilia, Tropical
Article | Year |
---|---|
t(4;12)(q12;p13) ETV6-rearranged AML without eosinophilia does not involve PDGFRA: relevance for imatinib insensitivity.
Topics: Eosinophilia; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Receptor Protein-Tyrosine Kinases; Retrospective Studies | 2022 |
[Successful treatment with imatinib for a patient with myeloid neoplasms with eosinophilia and abnormalities of PDGFRB due to t (5;14)(q33;q22)].
Topics: Eosinophilia; Humans; Imatinib Mesylate; Male; Middle Aged; Myeloproliferative Disorders; Neoplasms; Receptor, Platelet-Derived Growth Factor beta | 2021 |
[Myeloid neoplasms associated with rearrangement of PDGFRB: A rare and tricky disease].
Topics: Aged; Eosinophilia; Hematologic Neoplasms; Humans; Imatinib Mesylate; Immunoglobulins, Intravenous; In Situ Hybridization, Fluorescence; Male; Myeloproliferative Disorders; Receptor, Platelet-Derived Growth Factor beta | 2022 |
FIP1L1-PDGFRA fusion gene in T-lymphoblastic lymphoma: A case report.
Topics: Child; Eosinophilia; Humans; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Receptor, Platelet-Derived Growth Factor alpha | 2023 |
A challenging diagnosis of myeloid/lymphoid neoplasm with eosinophilia and FIP1L1::PDGFRA rearrangement.
Topics: Eosinophilia; Humans; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Neoplasms; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha | 2023 |
[Complete remission of Loeffler's endocarditis with Imatinib in a myeloid and lymphoid neoplasm associated with eosinophilia].
Topics: Antineoplastic Agents; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Lymphoma; Male; Middle Aged | 2020 |
Treatment-free remission in FIP1L1-PDGFRA-positive myeloid/lymphoid neoplasms with eosinophilia after imatinib discontinuation.
Topics: Eosinophilia; Hematologic Neoplasms; Humans; Imatinib Mesylate; Remission Induction; Retrospective Studies; Survival Rate | 2020 |
A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia.
Topics: DNA Helicases; Eosinophilia; Humans; Imatinib Mesylate; Male; Neoplasms; Poly-ADP-Ribose Binding Proteins; Receptor, Platelet-Derived Growth Factor beta; RNA Helicases; RNA Recognition Motif Proteins; Young Adult | 2020 |
A novel NAP1L4/NUTM1 fusion arising from translocation t(11;15)(p15;q12) in a myeloid neoplasm with eosinophilia and rearrangement of PDGFRA highlights an unusual clinical feature and therapeutic reaction.
Topics: Adult; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia; Male; Mutation; Myeloproliferative Disorders; Neoplasm Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha; Remission Induction; Translocation, Genetic | 2020 |
Imatinib as a potentially effective therapeutic alternative in corticosteroid-resistant eosinophilic fasciitis.
Topics: Adrenal Cortex Hormones; Child; Eosinophilia; Fasciitis; Humans; Imatinib Mesylate; Male | 2020 |
A Cryptic BCR-PDGFRB Fusion Resulting in a Chronic Myeloid Neoplasm With Monocytosis and Eosinophilia: A Novel Finding With Treatment Implications.
Topics: Eosinophilia; Humans; Imatinib Mesylate; Myeloproliferative Disorders; Neoplasms; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic | 2020 |
Identification of a Novel CSNK2A1-PDGFRB Fusion Gene in a Patient with Myeloid Neoplasm with Eosinophilia.
Topics: Adult; Biopsy; Bone Marrow; Casein Kinase II; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Male; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor beta; Treatment Outcome | 2021 |
Novel t(5;11)(q32;q13.4) with NUMA1-PDGFRB fusion in a myeloid neoplasm with eosinophilia with response to imatinib mesylate.
Topics: Antigens, Nuclear; Cell Cycle Proteins; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 5; Eosinophilia; Humans; Imatinib Mesylate; Male; Middle Aged; Myeloproliferative Disorders; Nuclear Matrix-Associated Proteins; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic; Treatment Outcome | 2017 |
Imatinib mesylate- and dasatinib-induced eosinophilia in a patient with chronic myelocytic leukemia.
Topics: Aged; Antineoplastic Agents; Dasatinib; Eosinophilia; Female; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Protein Kinase Inhibitors | 2017 |
Identification of a novel PDGFRA point mutation at p.P6L as a potential molecular target of imatinib in an eosinophilia patient showing genetic heterogeneity.
Topics: Adult; Antineoplastic Agents; Eosinophilia; Genetic Heterogeneity; Humans; Imatinib Mesylate; Male; Oncogene Proteins, Fusion; Point Mutation; Prognosis; Receptor, Platelet-Derived Growth Factor alpha | 2019 |
Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Induced by Imatinib.
Topics: Antineoplastic Agents; Eosinophilia; Exanthema; Female; Humans; Imatinib Mesylate; Middle Aged | 2019 |
Myeloid Neoplasm With Eosinophilia and FIP1L1-PDGFRA Rearrangement Treated With Imatinib Mesylate: A Pediatric Case With Long-term Follow-up.
Topics: Adolescent; Antineoplastic Agents; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha | 2019 |
Myeloid/Lymphoid Neoplasm with PDGFRB Rearrangement with t (5;10) (q33;q22) Harboring a Novel Breakpoint of the CCDC6-PDGFRB Fusion Gene.
Topics: Antineoplastic Agents; Cytoskeletal Proteins; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic | 2019 |
Long-term follow-up of treatment with imatinib in eosinophilia-associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase.
Topics: Antineoplastic Agents; Benzamides; Blast Crisis; Eosinophilia; Follow-Up Studies; Gene Rearrangement; Humans; Imatinib Mesylate; Leukemia, Myeloid; Lymphoma, T-Cell; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Prognosis; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Sarcoma, Myeloid; Survival Rate | 2013 |
Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia.
Topics: Benzamides; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Mutation; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome | 2014 |
Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable long-term remissions with imatinib.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Benzamides; Child; Child, Preschool; Eosinophilia; Female; Humans; Imatinib Mesylate; Infant; Leukemia, Myeloid; Male; Middle Aged; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Remission Induction; Translocation, Genetic; Young Adult | 2014 |
Identification and functional characterization of imatinib-sensitive DTD1-PDGFRB and CCDC88C-PDGFRB fusion genes in eosinophilia-associated myeloid/lymphoid neoplasms.
Topics: Adult; Amino Acid Sequence; Antineoplastic Agents; Benzamides; Chromosomes, Human, Pair 5; Chronic Disease; DNA-Binding Proteins; Eosinophilia; Gene Fusion; Humans; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Leukemia; Male; Microfilament Proteins; Molecular Sequence Data; Myeloproliferative Disorders; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Remission Induction; Translocation, Genetic | 2014 |
Relapse of myeloid neoplasm with eosinophilia and PDGFRA rearrangement after imatinib discontinuation in a pediatric patient.
Topics: Antineoplastic Agents; Benzamides; Child, Preschool; Eosinophilia; Female; Gene Rearrangement; Humans; Imatinib Mesylate; Myeloproliferative Disorders; Neoplasm Recurrence, Local; Piperazines; Prognosis; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Withholding Treatment | 2014 |
Comprehensive genomic profiling identifies a novel TNKS2-PDGFRA fusion that defines a myeloid neoplasm with eosinophilia that responded dramatically to imatinib therapy.
Topics: Benzamides; Eosinophilia; Female; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia; Middle Aged; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Tankyrases | 2015 |
Diagnostic challenges during pretreatment long-term follow-up in a patient with FIP1L1-PDGFRA-positive eosinophilia.
Topics: Adult; Antineoplastic Agents; Benzamides; Eosinophilia; Follow-Up Studies; Humans; Imatinib Mesylate; Leukemia, Myeloid; Male; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome | 2015 |
Strongyloidiasis in a diabetic patient accompanied by gastrointestinal stromal tumor: cause of eosinophilia unresponsive to steroid therapy.
Topics: Aged; Albendazole; Animals; Diabetes Mellitus, Type 2; Eosinophilia; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Steroids; Strongyloides stercoralis; Strongyloidiasis | 2015 |
Fusion of PDGFRB to MPRIP, CPSF6, and GOLGB1 in three patients with eosinophilia-associated myeloproliferative neoplasms.
Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Antineoplastic Agents; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 5; Cytogenetic Analysis; Eosinophilia; Gene Fusion; Golgi Matrix Proteins; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Male; Membrane Proteins; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Polymerase Chain Reaction; Receptor, Platelet-Derived Growth Factor beta; Remission Induction; Translocation, Genetic | 2015 |
Next generation sequencing of myeloid neoplasms with eosinophilia harboring the FIP1L1-PDGFRA mutation.
Topics: Adult; Aged; Bone Marrow; Disease-Free Survival; Eosinophilia; Eosinophils; Female; Humans; Imatinib Mesylate; Leukocyte Count; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Mutation; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha | 2016 |
[FIP1L1-PDGFRА-positive myeloproliferative disease with eosinophilia: A rare case with multiple organ dysfunction and a response to tyrosine kinase inhibitor therapy].
Topics: Adult; Dasatinib; Eosinophilia; Female; Humans; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Multiple Organ Failure; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor alpha | 2015 |
Pathological fracture due to lytic lesion caused by a myeloid neoplasm with FIP1L1-PDGFRA.
Topics: Adult; Eosinophilia; Femur Neck; Fractures, Bone; Humans; Imatinib Mesylate; Male; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Neoplasms; Oncogene Proteins, Fusion; Receptor, Platelet-Derived Growth Factor alpha | 2016 |
Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2).
Topics: Antineoplastic Agents; Benzamides; Chromosome Painting; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 5; Eosinophilia; Gene Fusion; Humans; Imatinib Mesylate; Male; Middle Aged; Mutant Chimeric Proteins; Myelodysplastic-Myeloproliferative Diseases; Myosins; Piperazines; Polymerase Chain Reaction; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic | 2009 |
[Hematological disorders and hypereosinophilias].
Topics: Antineoplastic Agents; Benzamides; Eosinophilia; Gene Rearrangement; Glucocorticoids; Hematologic Diseases; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukemia; Piperazines; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta | 2009 |
Myeloproliferative disorder with eosinophilia and ETV6-ABL gene rearrangement: efficacy of second-generation tyrosine kinase inhibitors.
Topics: Benzamides; Eosinophilia; Female; Gene Rearrangement; Humans; Imatinib Mesylate; Middle Aged; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Remission Induction | 2009 |
[Eosinophils and related diseases].
Topics: Antineoplastic Agents; Autoimmune Diseases; Benzamides; Cell Differentiation; Cell Movement; Cell Survival; Eosinophilia; Eosinophils; Helminthiasis; Humans; Hypereosinophilic Syndrome; Hypersensitivity; Imatinib Mesylate; Piperazines; Pyrimidines | 2009 |
Acute myeloid leukemia with myeloid sarcoma and eosinophilia: prolonged remission and molecular response to imatinib.
Topics: Antineoplastic Agents; Benzamides; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myeloid, Acute; Middle Aged; Piperazines; Pyrimidines; Remission Induction; Sarcoma, Myeloid | 2010 |
Myeloid neoplasm with prominent eosinophilia and PDGFRA rearrangement treated with imatinib mesylate.
Topics: Benzamides; Child, Preschool; Eosinophilia; Female; Gene Rearrangement; Humans; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha | 2010 |
A case of myeloid neoplasm associated with eosinophilia and KIAA1509-PDGFRβ responsive to combination treatment with imatinib mesylate and prednisolone.
Topics: Adult; Antineoplastic Agents, Hormonal; Benzamides; Drug Therapy, Combination; Eosinophilia; Eosinophils; Female; Gene Fusion; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Leukocyte Count; Myeloproliferative Disorders; Piperazines; Prednisolone; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta | 2010 |
Metastatic uterine leiomyosarcoma and eosinophilia.
Topics: Antineoplastic Agents; Benzamides; Dyspnea; Eosinophilia; Fatal Outcome; Female; Humans; Hydroxyurea; Imatinib Mesylate; Leiomyosarcoma; Liver Neoplasms; Lung Neoplasms; Middle Aged; Piperazines; Prednisone; Pyrimidines; Splenic Neoplasms; Uterine Neoplasms | 2011 |
[Clonal eosinophilia revealed by recurrent Staphylococcus aureus infection].
Topics: Anti-Bacterial Agents; Benzamides; Biomarkers; Clone Cells; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Recurrence; Risk Factors; Smoking; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2011 |
Congenital and childhood myeloproliferative disorders with eosinophilia responsive to imatinib.
Topics: Antineoplastic Agents; Benzamides; Child, Preschool; Eosinophilia; Humans; Imatinib Mesylate; Infant, Newborn; Infant, Newborn, Diseases; Male; Myeloproliferative Disorders; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta | 2012 |
Long-term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome.
Topics: Adult; Aged; Benzamides; Eosinophilia; Female; Follow-Up Studies; Humans; Imatinib Mesylate; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Mutation; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Survival Analysis; Treatment Outcome | 2012 |
Case of polycythemia vera concurrent with FIP1L1-PDGFRA-positive myeloproliferative neoplasm with eosinophilia.
Topics: Antineoplastic Agents; Benzamides; Biopsy; Eosinophilia; Genetic Predisposition to Disease; Humans; Imatinib Mesylate; Male; Middle Aged; Models, Genetic; mRNA Cleavage and Polyadenylation Factors; Mutation; Myeloproliferative Disorders; Piperazines; Polycythemia Vera; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Remission Induction | 2012 |
[Myeloproliferative hypereosinophilic syndrome revealed by bipolar mucosal ulcerations].
Topics: Antineoplastic Agents; Benzamides; Biopsy; Bone Marrow; Diagnosis, Differential; Eosinophilia; Humans; Imatinib Mesylate; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Mucous Membrane; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pulmonary Eosinophilia; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Skin Ulcer | 2012 |
Recurrent CEP85L-PDGFRB fusion in patient with t(5;6) and imatinib-responsive myeloproliferative neoplasm with eosinophilia.
Topics: Amino Acid Sequence; Antineoplastic Agents; Base Sequence; Benzamides; Chromosome Breakpoints; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 6; Eosinophilia; Humans; Imatinib Mesylate; Male; Middle Aged; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic; Treatment Outcome | 2013 |
A 32-year-old man with persistent cough, shortness of breath, eosinophilic pneumonia, and peripheral blood eosinophilia. Myeloid neoplasm associated with eosinophilia and platelet-derived growth factor receptor-alpha rearrangement.
Topics: Adult; Antineoplastic Agents; Benzamides; Bone Marrow Neoplasms; Cough; Dyspnea; Eosinophilia; Gene Rearrangement; Humans; Imatinib Mesylate; Male; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Pulmonary Eosinophilia; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Steroids; Treatment Outcome | 2012 |
Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta.
Topics: Adult; Aged; Benzamides; Child; Chromosomes, Human, Pair 5; DNA-Binding Proteins; Eosinophilia; ETS Translocation Variant 6 Protein; Gene Rearrangement; Humans; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Leukocytosis; Male; Middle Aged; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-ets; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Repressor Proteins | 2002 |
The hypereosinophilic syndrome and the biology of cancer.
Topics: Benzamides; Chromosome Deletion; Enzyme Inhibitors; Eosinophilia; Eosinophils; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Neoplasms; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; T-Lymphocytes; Translocation, Genetic | 2003 |
Response to STI571 in chronic myelomonocytic leukemia with platelet derived growth factor beta receptor involvement: a new case report.
Topics: Aged; Antineoplastic Agents; Benzamides; Enzyme Inhibitors; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myelomonocytic, Chronic; Male; Myelodysplastic Syndromes; Myeloproliferative Disorders; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Translocation, Genetic | 2003 |
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Eosinophilia; Gene Rearrangement; Hematopoietic Stem Cells; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Mastocytosis, Systemic; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Predictive Value of Tests; Prospective Studies; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Treatment Outcome | 2003 |
Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib.
Topics: Benzamides; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 5; Clone Cells; Cloning, Molecular; Eosinophilia; Female; Humans; Imatinib Mesylate; Infant; Microtubule-Associated Proteins; Myeloproliferative Disorders; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Remission Induction; Translocation, Genetic | 2003 |
The idiopathic hypereosinophilic syndrome and eosinophilic leukemias.
Topics: Benzamides; Clone Cells; Cytokines; Eosinophilia; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Lymphoma; Models, Biological; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; T-Lymphocyte Subsets | 2004 |
Immunophenotypic normalization of aberrant mast cells accompanies histological remission in imatinib-treated patients with eosinophilia-associated mastocytosis.
Topics: Adult; Benzamides; Bone Marrow Cells; Eosinophilia; Humans; Imatinib Mesylate; Immunophenotyping; Male; Mast Cells; Mastocytosis, Systemic; Piperazines; Pyrimidines | 2004 |
FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Bone Marrow; Cohort Studies; DNA-Binding Proteins; Eosinophilia; Female; Gene Deletion; Humans; Imatinib Mesylate; Incidence; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Prevalence; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Severity of Illness Index; Transcription Factors | 2004 |
p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder.
Topics: Aged; Amino Acid Sequence; Antineoplastic Agents; Base Sequence; Benzamides; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 5; Eosinophilia; Humans; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Male; Molecular Sequence Data; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Phosphoproteins; Piperazines; Proto-Oncogene Proteins c-sis; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tumor Suppressor p53-Binding Protein 1 | 2004 |
Concomitant eosinophilia, fasciitis, and mycosis fungoides-like reaction with antinuclear autoantibodies in chronic myeloid leukaemia: role of a T-cell clone induced by imatinib.
Topics: Aged; Antibodies, Antinuclear; Antineoplastic Agents; Benzamides; Eosinophilia; Fasciitis; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mycosis Fungoides; Piperazines; Pseudolymphoma; Pyrimidines | 2005 |
FIP1L1-PDGFRA in eosinophilic disorders: prevalence in routine clinical practice, long-term experience with imatinib therapy, and a critical review of the literature.
Topics: Adult; Aged; Benzamides; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Eosinophilia; Follow-Up Studies; Humans; Imatinib Mesylate; Male; Maximum Tolerated Dose; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Mutation; Oncogene Proteins, Fusion; Piperazines; Prevalence; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Recurrence; Remission Induction; Treatment Outcome | 2006 |
First case of an AIDS patient with systemic mast cell disease associated with FIP1-positive eosinophilia treated with imatinib mesylate therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Agents; Benzamides; Eosinophilia; Humans; Imatinib Mesylate; Male; Mastocytosis, Systemic; Monomeric GTP-Binding Proteins; Piperazines; Polymorphism, Restriction Fragment Length; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Imatinib-responsive hypereosinophilic syndrome.
Topics: Benzamides; Dose-Response Relationship, Drug; Eosinophilia; Follow-Up Studies; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Remission Induction; Treatment Outcome | 2006 |
The results of imatinib therapy for patients with primary eosinophilic disorders.
Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Drug Evaluation; Eosinophilia; Female; Follow-Up Studies; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Neoplasm Proteins; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Treatment Outcome | 2006 |
Imatinib-induced cytogenetic remission in chronic eosinophilic leukaemia.
Topics: Benzamides; Chronic Disease; Cytogenetic Analysis; Eosinophilia; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Piperazines; Pyrimidines; Remission Induction | 2006 |
Successful treatment with imatinib mesylate in a case of chronic myeloproliferative disorder with a t(5;12)(q33;p13.1) without eosinophilia.
Topics: Benzamides; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 5; Chronic Disease; Eosinophilia; Humans; Imatinib Mesylate; Male; Middle Aged; Myeloproliferative Disorders; Piperazines; Pyrimidines; Translocation, Genetic | 2006 |
Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Child; Child, Preschool; Drug Evaluation; Eosinophilia; Female; Follow-Up Studies; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Infant; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Middle Aged; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Translocation, Genetic; Treatment Outcome | 2007 |
'Idiopathic' eosinophilia with an Occult T-cell clone: prevalence and clinical course.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clone Cells; Cyclophosphamide; Eosinophilia; Female; Humans; Imatinib Mesylate; Leukemia, Lymphoid; Lymphoma, T-Cell, Peripheral; Male; Methotrexate; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Prevalence; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; T-Lymphocytes | 2007 |
Charcot-Leyden crystals in the trephine biopsy of a patient with a FIP1L1-PDGFRA - positive myeloproliferative disorder.
Topics: Antineoplastic Agents; Benzamides; Biopsy; Bone Marrow; Bone Marrow Examination; Crystallization; Eosinophilia; Glycoproteins; Humans; Imatinib Mesylate; Lysophospholipase; Male; Middle Aged; mRNA Cleavage and Polyadenylation Factors; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha | 2007 |
Episodic angioedema with eosinophilia: successful treatment with imatinib.
Topics: Angioedema; Antineoplastic Agents; Benzamides; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Diagnosis, Differential; Eosinophilia; Female; Humans; Imatinib Mesylate; Middle Aged; Piperazines; Pyrimidines; Recurrence | 2008 |
Multiple brain infarctions induced by imatinib mesylate in a patient with clonal eosinophilia.
Topics: Benzamides; Brain Infarction; Eosinophilia; Humans; Imatinib Mesylate; Magnetic Resonance Imaging; Male; Middle Aged; Piperazines; Pyrimidines | 2008 |