imatinib mesylate and Disease Models, Animal

Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

Topics: Animals; Autoimmune Diseases; Benzamides; Cell Growth Processes; Cytokines; Disease Models, Animal; Humans; Imatinib Mesylate; Immunomodulation; Inflammation Mediators; Patents as Topic; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction

Topics: Alveolar Epithelial Cells; Animals; Benzamides; Disease Models, Animal; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Signal Transduction

Topics: Animals; Benzamides; Chronic Disease; Disease Models, Animal; Eosinophils; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Mastocytosis; Mice; mRNA Cleavage and Polyadenylation Factors; Oncogene Proteins, Fusion; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction

Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Disease Models, Animal; Drug Evaluation, Preclinical; ErbB Receptors; Genetic Engineering; Humans; Imatinib Mesylate; Mice; Neoplasm Transplantation; Neoplasms; Piperazines; Pyrimidines; Transplantation, Heterologous; Trastuzumab

Topics: Adaptive Immunity; Animals; Arthritis, Rheumatoid; Benzamides; Disease Models, Animal; Female; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Immunity, Innate; Male; Mast Cells; Mice; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Scleroderma, Systemic

Topics: Animals; Benzamides; Clinical Trials as Topic; Disease Models, Animal; Humans; Imatinib Mesylate; Mice; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Scleroderma, Systemic

Topics: 5-Lipoxygenase-Activating Proteins; Animals; Benzamides; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Neoplastic Stem Cells; Philadelphia Chromosome; Piperazines; Point Mutation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; PTEN Phosphohydrolase; Pyrimidines

Topics: Animals; Antineoplastic Agents; Benzamides; Dasatinib; Disease Models, Animal; History, 19th Century; Humans; Imatinib Mesylate; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Philadelphia Chromosome; Piperazines; Pyrimidines; Thiazoles; Tretinoin

Topics: Amyloidosis; Animals; Benzamides; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibrosis; Humans; Imatinib Mesylate; Islets of Langerhans; Mice; Pancreatic Diseases; Piperazines; Protein Kinase Inhibitors; Pyrimidines

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Cardiomyoplasty; Colorectal Neoplasms; Cyclooxygenase 2; Disease Models, Animal; ErbB Receptors; Gastrointestinal Diseases; Genes, abl; Genetic Engineering; Humans; Imatinib Mesylate; Isoenzymes; Membrane Proteins; Mice; Mice, Transgenic; Neoplasms; Piperazines; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Receptors, Transforming Growth Factor beta; Skin Abnormalities; Trastuzumab; Vascular Endothelial Growth Factor A

Topics: Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Humans; Imatinib Mesylate; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Research Design

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Genes, abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Oncogene Proteins v-abl; Piperazines; Proto-Oncogene Proteins c-abl; Pyrimidines

Topics: Animals; Benzamides; Disease Models, Animal; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pulmonary Artery; Pyrimidines; Receptors, Platelet-Derived Growth Factor

Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Asthma; Benzamides; Dermatitis; Disease Models, Animal; Eosinophils; Humans; Imatinib Mesylate; Inflammation; Mast Cells; Models, Molecular; Piperazines; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Signal Transduction; Stem Cell Factor

Topics: Animals; Benzamides; Disease Models, Animal; Genes, abl; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Transgenic; Piperazines; Pyrimidines

Topics: Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Imatinib Mesylate; Interleukin-7; Mice; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Tumor Suppressor Protein p14ARF

Topics: Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzamides; Disease Models, Animal; Humans; Imatinib Mesylate; Leukemia; Oxides; Piperazines; Pyrimidines; Tretinoin

Topics: Animals; Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein-Tyrosine Kinases; Pyrimidines

Topics: Animals; Antineoplastic Agents; Benzamides; Clinical Trials, Phase I as Topic; Disease Models, Animal; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Sensitivity and Specificity

Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus

Topics: Adolescent; Animals; Animals, Newborn; Antineoplastic Agents; Benzamides; Body Height; Bone Development; Child; Disease Models, Animal; Female; Follow-Up Studies; Humans; Imatinib Mesylate; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar

Topics: Adult; Aged; Animals; Benzamides; Cell Division; Dichloroacetic Acid; Disease Models, Animal; Drug Monitoring; Familial Primary Pulmonary Hypertension; Female; Fibroblasts; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Gene Expression Profiling; Glycolysis; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Indoles; Lung; Male; Middle Aged; Monocrotaline; Piperazines; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Sunitinib; Young Adult

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Death; Cell Line; Cell Respiration; Diabetes Mellitus; Disease Models, Animal; Energy Metabolism; Enoyl-CoA Hydratase; Enzyme Activation; Humans; Hypoglycemic Agents; Imatinib Mesylate; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Male; Mice, Inbred NOD; Mitochondria; Phosphorylation; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Ribosomal Protein S6

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Disease Models, Animal; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Mice; Mutation; Phosphorylation; Proto-Oncogene Proteins c-kit; Pyrazoles; Signal Transduction

Topics: 3' Untranslated Regions; Animals; Apoptosis; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Disease Models, Animal; Disease Progression; DNA Breaks, Double-Stranded; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Gene Ontology; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes; Mice, Inbred C57BL; MicroRNAs; RNA, Messenger; Up-Regulation

Topics: Animals; Disease Models, Animal; Ferroptosis; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Mice; Protein Kinase Inhibitors

Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Fusion Proteins, bcr-abl; GATA3 Transcription Factor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, abl; Humans; Imatinib Mesylate; Mice, Knockout; Protein Kinase Inhibitors; RNA, Long Noncoding; STAT5 Transcription Factor; Xenograft Model Antitumor Assays

Topics: Animals; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Imatinib Mesylate; MicroRNAs; Monocrotaline; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats

Topics: Animals; Brain Injuries; Cell Death; Cerebral Hemorrhage; Disease Models, Animal; Imatinib Mesylate; Male; Neuroinflammatory Diseases; Rats; Rats, Sprague-Dawley; Tenascin

Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Imatinib Mesylate; Mice; Pentylenetetrazole; Pilocarpine; Seizures; Status Epilepticus; Valproic Acid

Topics: Animals; Disease Models, Animal; Humans; Imatinib Mesylate; Imiquimod; Keratinocytes; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Skin Diseases; Vascular Endothelial Growth Factor A

Topics: Animals; Collagen; Disease Models, Animal; Hydrogen-Ion Concentration; Imatinib Mesylate; Liver; Liver Cirrhosis; Mice; Nanoparticles; Polymers

Topics: Animals; Autoantibodies; Cytokines; Disease Models, Animal; Humans; Imatinib Mesylate; Interferons; Leukocytes, Mononuclear; Lupus Erythematosus, Systemic; Mice; Mice, Inbred MRL lpr; Molecular Docking Simulation; NF-kappa B

Topics: Animals; Antineoplastic Agents; Bayes Theorem; Disease Models, Animal; Drug Resistance, Neoplasm; Exosomes; Female; Heterografts; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Rats

Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antineoplastic Agents; Behavior, Animal; Cell Line, Tumor; Cell Movement; Depression; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Imatinib Mesylate; Inflammation Mediators; Male; Mice; Mice, Nude; Prognosis; Proto-Oncogene Proteins c-abl; Reactive Oxygen Species; Signal Transduction; Stomach Neoplasms

Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Proliferation; Disease Models, Animal; Drug Liberation; Fibroblasts; Gold; Humans; Imatinib Mesylate; Lung; Macrophages, Alveolar; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Scleroderma, Systemic

Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Membrane; Disease Models, Animal; Disease Progression; Female; Imatinib Mesylate; Inflammation; Lung Neoplasms; Membrane Potentials; Mitochondria; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Microenvironment

Topics: Animals; Apoptosis; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colonic Neoplasms; Disease Models, Animal; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Immunity; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic; Protein Kinase Inhibitors; Receptors, Antigen, T-Cell; T-Lymphocytes, Regulatory; Treatment Outcome

Topics: Acute Disease; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Brain; Cold Temperature; Corticosterone; Disease Models, Animal; Exploratory Behavior; Female; Imatinib Mesylate; Immersion; Locomotion; Male; Mice; Motor Activity; Protein Kinase Inhibitors; Social Behavior; Stress, Psychological; Tetrabenazine; Vesicular Monoamine Transport Proteins

Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Disease Models, Animal; Hepatitis C, Chronic; Heterografts; Humans; Imatinib Mesylate; Liver Neoplasms; Mice; Neoplasm Transplantation; Treatment Outcome; Xenograft Model Antitumor Assays

Topics: Animals; Disease Models, Animal; Embryo Transfer; Embryonic Development; Female; Fertilization in Vitro; Humans; Imatinib Mesylate; Mice; Oocytes; Ovarian Follicle; Ovarian Reserve; Superovulation

Topics: Animals; Bone Marrow; Carbon Tetrachloride; Combined Modality Therapy; Disease Models, Animal; Imatinib Mesylate; Liver; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor

Topics: Administration, Oral; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Caspase 3; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucagon; Glutathione; Imatinib Mesylate; Insulin; Insulin-Secreting Cells; Male; Malondialdehyde; Organ Size; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase

Topics: Angiogenesis Inhibitors; Animals; Computer Simulation; Concanavalin A; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Hepatic Stellate Cells; Humans; Imatinib Mesylate; Liver; Liver Cirrhosis; Mice; Mice, Inbred BALB C; Protein Kinase Inhibitors; Receptors, Platelet-Derived Growth Factor; Sorafenib

Topics: Aged; Animals; Antibodies; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Imatinib Mesylate; Immune Checkpoint Inhibitors; Immunotherapy; Male; Mice; Mice, Inbred BALB C; Programmed Cell Death 1 Receptor; Protein Kinase Inhibitors; Retrospective Studies

Topics: Animals; Antineoplastic Agents; Blast Crisis; Chemoradiotherapy; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Knock-In Techniques; Gene Knockout Techniques; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Imatinib Mesylate; Integrin beta Chains; Leukemia, Myeloid, Acute; Mice, Transgenic; Neoplastic Stem Cells; RNA-Binding Proteins; RNA-Seq; Signal Transduction; Syndecan-1

Topics: Animals; Apoptosis; Bronchioles; Bronchiolitis Obliterans; Disease Models, Animal; Fibroblasts; Gold; Humans; Hyaluronan Receptors; Imatinib Mesylate; Lung; Lung Transplantation; Lymphocytes; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Trachea; Transforming Growth Factor beta

Topics: Adult; Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal, Humanized; Cohort Studies; Dasatinib; Disease Models, Animal; Female; Glaucoma; Humans; Imatinib Mesylate; Intraocular Pressure; Male; Mice; Middle Aged; Retinal Ganglion Cells; Retrospective Studies; Vision, Ocular; Visual Acuity

Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Disease Susceptibility; Gene Expression; Hippocampus; Imatinib Mesylate; Male; Mice, Inbred C57BL; Neuroglia; Pericytes; Pilocarpine; Receptor, Platelet-Derived Growth Factor beta; Seizures; Time Factors

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arachidonate 5-Lipoxygenase; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Gene Silencing; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; MAP Kinase Signaling System; Middle Aged; Mutation; Phosphorylation; Protein Kinase C beta; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Survival Analysis; Up-Regulation; Young Adult

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Primary Cell Culture; Quinazolines; SOXD Transcription Factors; Xenograft Model Antitumor Assays

Topics: Animals; Biomarkers; Discoidin Domain Receptor 1; Discoidin Domain Receptor 2; Discoidin Domain Receptors; Disease Models, Animal; Disease Outbreaks; Disease Progression; Fibrosis; Gene Expression Regulation; Humans; Imatinib Mesylate; Immunohistochemistry; Mice; Pancreatitis, Chronic; Protein Kinase Inhibitors; Signal Transduction

Topics: Animals; Disease Models, Animal; Female; Humans; Imatinib Mesylate; Kidney; Lupus Nephritis; Male; Mice; Particle Size

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Imatinib Mesylate; Male; Monocrotaline; Nerve Growth Factor; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Signal Transduction

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Carriers; Exosomes; HEK293 Cells; Heterografts; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Receptors, Interleukin-3; Treatment Outcome

Topics: Animals; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Erlotinib Hydrochloride; Fibrosis; Imatinib Mesylate; Keratin-19; Liver; Liver Cirrhosis; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Protein Kinase Inhibitors; Thioacetamide; Transforming Growth Factor beta

Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Disease Models, Animal; Genotype; Hematopoiesis, Extramedullary; Imatinib Mesylate; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Osteogenesis; Phenotype; Primary Myelofibrosis; Protein Kinase Inhibitors; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Leptin; Signal Transduction; Stem Cell Niche; Thrombopoietin; Time Factors

Topics: Animals; Antigens, CD34; Cell Proliferation; Cyclophosphamide; Cystitis, Interstitial; Disease Models, Animal; Female; Imatinib Mesylate; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor alpha

Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Endotoxemia; Imatinib Mesylate; Inflammation Mediators; Kidney; Lipopolysaccharides; Liver; Lung; Male; Neutrophils; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Indoles; Male; Monocrotaline; Nestin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pulmonary Artery; Pyrroles; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling

Topics: Animals; Disease Models, Animal; Imatinib Mesylate; Lung Injury; Lung Transplantation; Male; Protein Kinase Inhibitors; Rabbits; Reperfusion Injury

Topics: Animals; Antineoplastic Agents; Body Weight; Disease Models, Animal; Drug Resistance, Neoplasm; Exons; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Male; Mice; Mice, Nude; Mutation; Neoplasm Recurrence, Local; Phenylurea Compounds; Proto-Oncogene Proteins c-kit; Pyridines; Transplantation, Heterologous; Tumor Cells, Cultured

Topics: Animals; Biomarkers; CD40 Antigens; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chemotaxis, Leukocyte; Disease Models, Animal; Drug Synergism; Gastrointestinal Stromal Tumors; Gene Expression; Humans; Imatinib Mesylate; Immunophenotyping; Immunotherapy; Macrophages; Mice; Monocytes; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Models, Biological; NF-kappa B; Phosphopeptides; Proteomics; Proto-Oncogene Proteins; Signal Transduction; src-Family Kinases

Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Gene Editing; Genetic Vectors; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Neoplastic Stem Cells; Recombinational DNA Repair; Sequence Analysis, DNA; Xenograft Model Antitumor Assays; Zinc Finger Nucleases

Topics: Animals; Dialysis Solutions; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fucose; Fucosyltransferases; Glucose; Imatinib Mesylate; Male; Peritoneal Dialysis; Peritoneal Fibrosis; Peritoneum; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Receptors, Transforming Growth Factor beta; RNA Interference; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1

Topics: Adult; Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Case-Control Studies; CD4-Positive T-Lymphocytes; Chemokines; Chemotaxis; Dendritic Cells; Disease Models, Animal; Female; Fibrosis; Gene Expression; Humans; Imatinib Mesylate; Inflammation; Interleukin-4; Lung; Male; Mice; Protein Kinase Inhibitors; Receptors, Chemokine; Scleroderma, Systemic; Severity of Illness Index; Skin; Spleen; Transforming Growth Factor beta1; Young Adult

Topics: Animals; Antineoplastic Agents; Binding Sites; Biomarkers, Tumor; Cell Cycle; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Heat-Shock Response; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Protein Interaction Domains and Motifs; Protein Kinase Inhibitors; Protein Multimerization; Spectrum Analysis; Structure-Activity Relationship; Xenograft Model Antitumor Assays

Topics: Acute Kidney Injury; Animals; Capillary Permeability; Cardiopulmonary Bypass; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Imatinib Mesylate; Inflammation Mediators; Male; Microcirculation; Microscopy, Electron; Oxygen Consumption; Premedication; Protein Kinase Inhibitors; Random Allocation; Rats, Wistar

Topics: Angiogenesis Inhibitors; Animals; Cell Proliferation; Disease Models, Animal; Endothelial Cells; Fibroblast Growth Factor 2; Hypoxia-Inducible Factor 1, alpha Subunit; Imatinib Mesylate; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Pericytes; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Retina; Retinal Neovascularization; Vascular Endothelial Growth Factor A

Topics: Animals; Bile Duct Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cholangiocarcinoma; Disease Models, Animal; Endothelial Cells; Heterografts; Humans; Imatinib Mesylate; Liver; Lymphangiogenesis; Lymphokines; Male; Mice; Mice, SCID; Myofibroblasts; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Rats; Rats, Inbred F344; Receptor, Platelet-Derived Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor C

Topics: Animals; Autoimmunity; B-Lymphocytes; Cell Proliferation; Diabetes Mellitus, Type 1; Disease Models, Animal; Homeodomain Proteins; Hyperglycemia; Imatinib Mesylate; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Maf Transcription Factors, Large; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout

Topics: Animals; Antineoplastic Agents; Cohort Studies; Disease Models, Animal; Drug Repositioning; Humans; Imatinib Mesylate; Imidazoles; Male; Melanoma; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridazines; Xenograft Model Antitumor Assays

Topics: Administration, Intravenous; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Membrane; Cholestasis; Disease Models, Animal; Humans; Imatinib Mesylate; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Microvilli; Up-Regulation

Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Complex Mixtures; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Ikaros Transcription Factor; Imatinib Mesylate; Male; Mice, Inbred BALB C; Philadelphia Chromosome; Plant Extracts; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Signal Transduction; Trametes; Treatment Outcome

Topics: Animals; Benzamides; Blood-Brain Barrier; Brain; Central Nervous System; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Gene Expression Regulation; Imatinib Mesylate; Inflammation; Multiple Sclerosis; Neurons; Peptides; Piperazines; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Receptors, CCR2; Signal Transduction; Spinal Cord; T-Lymphocytes

Topics: Animals; Benzamides; Chlorhexidine; Disease Models, Animal; Imatinib Mesylate; Immunohistochemistry; Male; Peritoneal Fibrosis; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Transforming Growth Factor beta1

Topics: Animals; Apoptosis; Benzamides; Cytokines; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Immunomodulation; Leukocyte Count; Lymphocyte Depletion; Lymphocytes; Male; Monocrotaline; Myocytes, Cardiac; Piperazines; Pyrimidines; Rats; Rats, Inbred F344; Rats, Nude

Topics: Acute Kidney Injury; Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzamides; Cisplatin; Disease Models, Animal; Female; Imatinib Mesylate; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Mutation; Nuclear Localization Signals; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; STAT1 Transcription Factor; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzamides; Cognition Disorders; Disease Models, Animal; Down-Regulation; Endotoxins; Hippocampus; Humans; Imatinib Mesylate; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Piperazines; Pyrimidines

Topics: Acute Lung Injury; Animals; Benzamides; Disease Models, Animal; Female; Imatinib Mesylate; Lipopolysaccharides; Mice; Mice, Inbred ICR; Neutropenia; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Random Allocation; Recovery of Function; Treatment Outcome

Topics: Administration, Inhalation; Administration, Oral; Animals; Benzamides; Bronchoalveolar Lavage Fluid; Cell Proliferation; Comorbidity; Cytokines; Disease Models, Animal; Eosinophils; Female; Imatinib Mesylate; Mice; Mice, Inbred C57BL; Myofibroblasts; Ovalbumin; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Respiratory Hypersensitivity; Vasculitis

Topics: Animals; Antihypertensive Agents; Arterial Pressure; Benzamides; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Muscle, Smooth, Vascular; Phosphodiesterase 4 Inhibitors; Piperazines; Potassium Channel Blockers; Protein Kinase Inhibitors; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Vasoconstriction; Vasodilation; Vasodilator Agents

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Benzamides; Cell Line, Tumor; Cell Proliferation; Codon; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Mice; mRNA Cleavage and Polyadenylation Factors; Mutation; Oncogene Proteins, Fusion; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyrimidines; Quinolines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Adult; Animals; Benzamides; Biopsy; Bleomycin; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fibrosis; Fos-Related Antigen-2; Humans; Imatinib Mesylate; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Molecular Targeted Therapy; Piperazines; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-sis; Pyrimidines; Scleroderma, Systemic; Skin; Treatment Outcome

Topics: Airway Remodeling; Animals; Asthma; Benzamides; Bronchi; Bronchial Hyperreactivity; Cells, Cultured; Chemokine CCL2; Disease Models, Animal; Female; Humans; Imatinib Mesylate; In Vitro Techniques; Interleukin-13; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Ovalbumin; Piperazines; Proliferating Cell Nuclear Antigen; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines

Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzamides; Blotting, Western; Bone Marrow Transplantation; Core Binding Factor Alpha 2 Subunit; Disease Models, Animal; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Mice, Inbred C57BL; Mice, Transgenic; Myeloproliferative Disorders; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Oxides; Piperazines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome

Topics: Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Mice; Models, Molecular; Piperazines; Positron-Emission Tomography; Proto-Oncogene Proteins c-kit; Pyrimidines

Topics: Analysis of Variance; Animals; Animals, Newborn; Benzamides; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hyperoxia; Hypoxia; Imatinib Mesylate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Piperazines; Platelet-Derived Growth Factor; Pulmonary Ventilation; Pyrimidines; Rats; Rats, Sprague-Dawley

Topics: Animals; Benzamides; Disease Models, Animal; Female; Hindlimb; Imatinib Mesylate; Motor Activity; Nerve Fibers, Myelinated; Nerve Regeneration; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Recovery of Function; Reflex; Spinal Cord Injuries; Urinary Bladder

Topics: Animals; Apoptosis; Benzamides; Disease Models, Animal; Imatinib Mesylate; Neurons; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tenascin; Vasospasm, Intracranial

Topics: Animals; Apoptosis; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chemokine CXCL12; Disease Models, Animal; Drug Synergism; Gene Expression; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mitochondria; Oligopeptides; Piperazines; Proto-Oncogene Mas; Pyrimidines; Receptors, CXCR4; Signal Transduction; Stromal Cells; Tumor Burden; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

Topics: Aminopyridines; Animals; Antineoplastic Agents; Benzamides; Biopsy; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Inhibitory Concentration 50; Mice, Knockout; Molecular Targeted Therapy; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Tumor Burden

Topics: Animals; Antineoplastic Agents; Benzamides; Caspases; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Humans; Imatinib Mesylate; Immunocompetence; Male; Mice; Mice, Inbred C57BL; Mitosis; Osteosarcoma; Piperazines; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; TOR Serine-Threonine Kinases

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Imatinib Mesylate; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Piperazines; Protein Kinase Inhibitors; Pyrimidines

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzamides; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Humans; Imatinib Mesylate; Mice; Mice, Transgenic; Mutation; Neuroblastoma; Peptide Fragments; Phosphorylation; Piperazines; Plaque, Amyloid; Presenilin-1; Proteins; Pyrimidines; Sarcosine; Statistics, Nonparametric; tau Proteins

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Becaplermin; Benzamides; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Rats, Wistar; Receptors, Platelet-Derived Growth Factor; rho-Associated Kinases; Ventricular Pressure

Topics: Adolescent; Animals; Antineoplastic Agents; Benzamides; Child; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Inhibins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Long-Term Care; Male; Piperazines; Protein Kinase Inhibitors; Puberty; Pyrimidines; Rats; Rats, Wistar; Sperm Count; Testis; Testosterone

Topics: Actins; Animals; Anti-Inflammatory Agents; Benzamides; Disease Models, Animal; Imatinib Mesylate; Inflammation; Interleukin-1; Interleukin-6; Liver; Liver Cirrhosis; Male; Piperazines; Pyrimidines; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Transforming Growth Factor beta1

Topics: Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Fusion Proteins, bcr-abl; Gene Knockdown Techniques; Genes, Neoplasm; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Targeted Therapy; Neoplastic Stem Cells; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Pyrimidines; raf Kinases; RNA, Small Interfering; Survival Analysis; Up-Regulation

Topics: Animals; Benzamides; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Disease Models, Animal; Imatinib Mesylate; Immunoprecipitation; Male; MAP Kinase Kinase 4; Neurologic Examination; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor alpha; Subarachnoid Hemorrhage

Topics: Active Transport, Cell Nucleus; Animals; Antihypertensive Agents; Apoptosis; Becaplermin; Benzamides; Cell Adhesion; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Humans; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Imatinib Mesylate; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Paxillin; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; RNA Interference; Signal Transduction; Time Factors; Transfection; Tyrosine; Vascular Remodeling

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Exons; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Imidazoles; Indoles; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Mutation; Neoplasm Recurrence, Local; Piperazines; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridazines; Pyrimidines; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Bone Marrow Cells; Cell Cycle; Cell Proliferation; Disease Models, Animal; Female; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; GRB10 Adaptor Protein; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; MicroRNAs; Piperazines; Primary Cell Culture; Pyrimidines; RNA, Small Interfering; Signal Transduction

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Disease Models, Animal; Drug Therapy, Combination; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Mice; Mitosis; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; PTEN Phosphohydrolase; Pyrimidines; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Benzamides; Brain Injuries; Disease Models, Animal; Imatinib Mesylate; In Situ Nick-End Labeling; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tenascin; Up-Regulation

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Dihydrolipoyllysine-Residue Acetyltransferase; Disease Models, Animal; Female; fms-Like Tyrosine Kinase 3; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Ketone Oxidoreductases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Oligomycins; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; RNA Interference; RNA, Small Interfering; Superoxides

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblast Growth Factors; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Ligands; MAP Kinase Signaling System; Phosphorylation; Protein Kinase Inhibitors; Proteome; Proteomics; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; DNA Mutational Analysis; Dogs; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Imatinib Mesylate; Mastocytosis; Mutation; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Signal Transduction; STAT3 Transcription Factor

Topics: Animals; Antihypertensive Agents; Arterial Pressure; Benzamides; Cell Proliferation; Deficiency Diseases; Dichloroacetic Acid; Disease Models, Animal; Erythropoiesis; Ferric Compounds; Ferritins; Glycolysis; Hematinics; Homeostasis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Iron; Iron Deficiencies; Liver; Male; Maltose; Piperazines; Pulmonary Artery; Pyrimidines; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Transferrin; Vascular Remodeling

Topics: Actins; Animals; Anti-Inflammatory Agents; Bleomycin; Bosentan; Catalase; Collagen Type I; Collagen Type II; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Oxidative Stress; Peroxidase; Pneumonia; Pulmonary Edema; RNA, Messenger; Sulfonamides; Superoxide Dismutase; Time Factors

Topics: Animals; Benzamides; Cells, Cultured; Disease Models, Animal; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nanoparticles; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor

Topics: Animals; Biomarkers; Cytokines; Disease Models, Animal; Female; Imatinib Mesylate; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Time Factors

Topics: Adenoviridae; Allografts; Animals; Becaplermin; Bone Morphogenetic Protein 7; Disease Models, Animal; Endothelial Cells; Genetic Therapy; Genetic Vectors; Heart Transplantation; Imatinib Mesylate; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-sis; Rats, Wistar; Receptors, Platelet-Derived Growth Factor; Time Factors

Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cell Nucleus; Disease Models, Animal; Endothelial Cells; Humans; Imatinib Mesylate; Inflammation; Lipopolysaccharides; Lung; Male; Mice, Inbred C57BL; Models, Biological; NF-kappa B; Phosphorylation; Protective Agents; Pulmonary Artery; Respiration, Artificial; Tumor Necrosis Factor-alpha; Ventilator-Induced Lung Injury

Topics: Animals; Biomarkers; Bleomycin; Cryptococcosis; Disease Models, Animal; Fibrosis; Imatinib Mesylate; Inflammation; Lung; Lung Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pulmonary Aspergillosis; X-Ray Microtomography

Topics: Animals; Antineoplastic Agents; Calcium; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Inhibitory Concentration 50; Lung Neoplasms; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Tumor Burden; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A; Vitamin D; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Heterografts; Humans; Imatinib Mesylate; Mice; Mutant Proteins; Proto-Oncogene Proteins c-abl; Treatment Outcome

Topics: Anastrozole; Angiogenesis Inhibitors; Animals; Aromatase Inhibitors; bcl-2-Associated X Protein; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Female; Imatinib Mesylate; Nitriles; Ovarian Follicle; Peritoneal Diseases; Peritoneum; Proto-Oncogene Proteins c-kit; Rats; Transplantation, Autologous; Triazoles; Vascular Endothelial Growth Factor A

Topics: Aminocaproic Acid; Animals; Basal Ganglia; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Encephalitis; Exploratory Behavior; Fibrinolysin; Fibrinolytic Agents; Gene Expression Regulation; Imatinib Mesylate; Macrophages; Male; Mice; Microglia; Nerve Tissue Proteins; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Receptor, Platelet-Derived Growth Factor beta; RNA, Small Interfering

Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Body Weight; Disease Models, Animal; Hippocampus; Imatinib Mesylate; Lipopolysaccharides; Male; Mice, Inbred C57BL; Phosphorylation; Protein Kinase Inhibitors; tau Proteins

Topics: Aniline Compounds; Animals; Cytokines; Disease Models, Animal; Imatinib Mesylate; Immunoglobulin G; Leishmania; Leishmaniasis; Macrophages; Mice; Models, Biological; Nitriles; Parasites; Phagocytosis; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Pyrimidines; Quinolines; RAW 264.7 Cells; Signal Transduction; src-Family Kinases

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Exome Sequencing; Gastrointestinal Stromal Tumors; Gene Expression Profiling; Heterocyclic Compounds, 3-Ring; Humans; Imatinib Mesylate; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Signal Transduction; Survival Analysis; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Biopsy, Needle; Bronchiolitis Obliterans; Cell Differentiation; Cell Movement; Cells, Cultured; Disease Models, Animal; Fibroblasts; Imatinib Mesylate; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Random Allocation; Sensitivity and Specificity; Statistics, Nonparametric

Topics: Animals; Anthracenes; Antineoplastic Agents; Brain Edema; Brain Injuries; Caspase 3; Disease Models, Animal; Double-Blind Method; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Imatinib Mesylate; In Situ Nick-End Labeling; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Subarachnoid Hemorrhage

Topics: Animals; Blotting, Western; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Imatinib Mesylate; Injections, Intraperitoneal; Lung; Lung Injury; Male; Protein Kinase Inhibitors; Rats; Rats, Inbred Lew; Reperfusion Injury; Tidal Volume

Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Collagen; Disease Models, Animal; Endothelial Cells; Extracellular Fluid; Female; Humans; Imatinib Mesylate; Immunohistochemistry; Mice; Pericytes; Protein Aggregates; Protein Kinase Inhibitors; Stromal Cells; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Naphthoquinones; Protein Kinase Inhibitors; Signal Transduction; STAT5 Transcription Factor; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Cell Survival; Desmoplakins; Disease Models, Animal; gamma Catenin; Heterografts; Histone Deacetylase Inhibitors; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Neoplastic Stem Cells; Treatment Outcome; Tumor Cells, Cultured

Topics: Anilides; Animals; Antineoplastic Agents; Apoptosis; Biopsy; Cell Line, Tumor; Disease Models, Animal; Female; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Mice; Mutation; Necrosis; Neoplasm Grading; Neovascularization, Pathologic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Animals; Choline Deficiency; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Ethionine; Hepatocytes; Imatinib Mesylate; Liver Cirrhosis; Liver Regeneration; Male; Mice, Inbred C57BL; Protein Kinase Inhibitors; Stem Cells

Topics: Animals; Cell Proliferation; Disease Models, Animal; Graft vs Host Disease; Imatinib Mesylate; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Scleroderma, Localized; T-Lymphocyte Subsets; T-Lymphocytes

Topics: Animals; Antineoplastic Agents; Biomarkers; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunohistochemistry; Male; Mice; Mice, Transgenic; Neuroendocrine Tumors; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Receptor, Platelet-Derived Growth Factor beta; Seminal Vesicles; Signal Transduction; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Carboxylic Ester Hydrolases; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Humans; Imatinib Mesylate; Male; Mice; Mice, Inbred ICR; Pregnane X Receptor; Receptors, Steroid; Structure-Activity Relationship; Tumor Cells, Cultured

Topics: Adipocytes; Adipose Tissue; Animals; Biomarkers; Denervation; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Imatinib Mesylate; Mice; Muscle, Skeletal; Protein Kinase Inhibitors; Receptors, Platelet-Derived Growth Factor; Rotator Cuff Injuries; Signal Transduction; Tendons

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Benzamides; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Hippocampus; Imatinib Mesylate; Male; Maze Learning; Mice; Mice, Transgenic; Nuclear Proteins; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-abl; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; tau Proteins; Tumor Protein p73; Tumor Suppressor Proteins

Topics: Animals; Becaplermin; Benzamides; Capillary Permeability; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Ephrin-B2; Humans; Hypertension, Portal; Image Processing, Computer-Assisted; Imatinib Mesylate; Liver; Mice; Microscopy, Confocal; Microscopy, Video; Neovascularization, Physiologic; NIH 3T3 Cells; Pericytes; Phenotype; Piperazines; Platelet-Derived Growth Factor; Portal Pressure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Receptors, Platelet-Derived Growth Factor; RNA Interference; Signal Transduction; Time Factors; Transfection

Topics: Animals; Apoptosis; Benzamides; Cell Survival; Cerebellar Cortex; Disease Models, Animal; DNA-Binding Proteins; Gene Expression; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Motor Activity; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Nuclear Proteins; Piperazines; Proteins; Proto-Oncogene Proteins c-abl; Purkinje Cells; Pyrimidines; RNA, Messenger; Tumor Protein p73; Tumor Suppressor Proteins

Topics: Animals; Benzamides; Blood-Brain Barrier; Brain; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Lymphokines; Mice; Models, Biological; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Radiography; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Stroke; Time Factors

Topics: Animals; Benzamides; Catheterization; Cell Division; Cells, Cultured; Disease Models, Animal; Hyperplasia; Imatinib Mesylate; Male; Muscle, Smooth, Vascular; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Tunica Intima; Tunica Media

Topics: Animals; Benzamides; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Estradiol; Female; Homozygote; Imatinib Mesylate; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Macrophage Colony-Stimulating Factor; Time Factors

Topics: Animals; Antibiotics, Antineoplastic; Benzamides; Bleomycin; Disease Models, Animal; Fibrillins; Fibrosis; Imatinib Mesylate; Mice; Mice, Inbred DBA; Mice, Mutant Strains; Microfilament Proteins; Phenotype; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Scleroderma, Systemic; Skin; Skin Diseases

Topics: Animals; Arsenicals; Benzamides; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Fusion Proteins, bcr-abl; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Models, Molecular; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Piperazines; Proteasome Endopeptidase Complex; Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Pyrimidines; Signal Transduction; Sulfides; Survival Rate; Systems Biology; TOR Serine-Threonine Kinases; Ubiquitins

Topics: Animals; Antineoplastic Agents; Benzamides; Core Binding Factor Alpha 2 Subunit; Disease Models, Animal; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Knock-In Techniques; Genotype; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Leukemia, Myelomonocytic, Chronic; Mice; Mice, Transgenic; Myeloproliferative Disorders; Oncogene Proteins, Fusion; Piperazines; Pyrimidines; RUNX1 Translocation Partner 1 Protein; Spleen

Topics: Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Imatinib Mesylate; Kidney; Kidney Diseases; Male; Piperazines; Proto-Oncogene Proteins c-abl; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Smad2 Protein; Smad3 Protein; Transcription Factors; Transforming Growth Factor beta; Ureteral Obstruction

Topics: Adolescent; Adult; Animals; Benzamides; Brain Neoplasms; Cell Line, Tumor; Cell Size; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Ki-67 Antigen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Neoplasm Transplantation; Neurofibroma, Plexiform; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; S100 Proteins; Schwann Cells; Young Adult

Topics: Animals; Antineoplastic Agents; Benzamides; Bone Marrow Cells; Cell Line; Cell Transplantation; Disease Models, Animal; Fusion Proteins, bcr-abl; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Signal Transduction; Transduction, Genetic; Translational Research, Biomedical

Topics: Animals; Benzamides; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Imatinib Mesylate; Kidney Failure, Chronic; Male; Mice; Mice, Inbred BALB C; Nephrectomy; Oxidative Stress; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Uremia

Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Binding Sites; Bone Marrow Transplantation; Cell Line, Tumor; Crystallization; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Inhibitory Concentration 50; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mass Spectrometry; Mice; Models, Molecular; Mutation; Piperazines; Protein Structure, Tertiary; Pyrimidines; Transplantation, Heterologous

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Disease Models, Animal; Enzyme Activation; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Signal Transduction; Transforming Growth Factor beta; Tumor Stem Cell Assay

Topics: Animals; Antigens, Ly; Benzamides; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Proteins; Mice; Neoplastic Stem Cells; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines

Topics: Administration, Oral; Animals; Benzamides; Disease Models, Animal; Disease Progression; Imatinib Mesylate; Liver Cirrhosis; Liver Function Tests; Male; Oxidative Stress; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Wistar; Silymarin; Thioacetamide

Topics: Animals; Benzamides; Clinical Trials as Topic; Dasatinib; Disease Models, Animal; Drugs, Investigational; ErbB Receptors; Fibrosis; Graft vs Host Disease; Humans; Imatinib Mesylate; Mixed Connective Tissue Disease; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Pulmonary Fibrosis; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Scleroderma, Systemic; Thiazoles

Topics: Animals; Antineoplastic Agents; Benzamides; Blast Crisis; Bone Marrow Cells; Cattle; Cell Line, Tumor; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred NOD; Mice, SCID; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Neoplasm Transplantation; Phosphorylation; Piperazines; Pyrimidines; Signal Transduction; Transplantation, Heterologous

Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Transplantation, Isogeneic; Treatment Outcome

Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Line, Tumor; Disease Models, Animal; Humans; Imatinib Mesylate; Liposomes; Male; Mice; Mice, Nude; Mitoxantrone; Piperazines; Prostatic Neoplasms; Pyrimidines; Xenograft Model Antitumor Assays

Topics: Acetaminophen; Analgesics; Animals; Antineoplastic Agents; Benzamides; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Interactions; Imatinib Mesylate; Kidney; Liver; Male; Mice; Mice, Inbred ICR; Piperazines; Pyrimidines

Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Dasatinib; Disease Models, Animal; Down-Regulation; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Integrins; Mice; Neoplasm Proteins; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Reproducibility of Results; Signal Transduction; src-Family Kinases; Thiazoles; Up-Regulation

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzamides; Cell Line; Disease Models, Animal; Gene Knockdown Techniques; Humans; Imatinib Mesylate; Mice; Peptide Fragments; Piperazines; Proteins; Pyrimidines; Receptor, Notch1; RNA Interference

Topics: Animals; Animals, Newborn; Apoptosis; Benzamides; Cataract; Cell Movement; Cell Proliferation; Disease Models, Animal; Epithelial Cells; Imatinib Mesylate; In Situ Nick-End Labeling; Lens, Crystalline; Mice; Mice, Inbred BALB C; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Time Factors

Topics: Animals; Antigen-Antibody Reactions; Arthritis; Autoimmune Diseases; Benzamides; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Disease Models, Animal; Gene Expression; Glucose-6-Phosphate Isomerase; Imatinib Mesylate; Interleukin-17; Male; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Recombinant Proteins; Spleen

Topics: Acetylcysteine; Animals; Benzamides; Brain; Case-Control Studies; Cell Line; Disease Models, Animal; Dopamine; Drug Administration Schedule; Free Radical Scavengers; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Imatinib Mesylate; Immunoprecipitation; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Oxidative Stress; Peptide Elongation Factors; Phosphorylation; Piperazines; Polyethylene Glycols; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; RNA, Small Interfering; Statistics, Nonparametric; Transfection; Tumor Suppressor Proteins; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzamides; Brain; Calcium-Binding Proteins; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 7; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Homeodomain Proteins; Humans; Imatinib Mesylate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Piperazines; Presenilin-2; Protein Kinase Inhibitors; Pyrimidines; Quantitative Trait Loci; Repressor Proteins; RNA, Messenger; Zinc Finger E-box Binding Homeobox 2

Topics: Animals; Antihypertensive Agents; Benzamides; Benzenesulfonates; Blotting, Western; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Imatinib Mesylate; Male; Myosin Light Chains; Myosin-Light-Chain Phosphatase; Niacinamide; Phenylurea Compounds; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pulmonary Artery; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sorafenib; Vasodilation; Vasodilator Agents; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Cell Proliferation; Disease Models, Animal; Global Health; Humans; Imatinib Mesylate; Medical Oncology; Mice; Neoplasms; Neoplastic Stem Cells; Piperazines; Pyrimidines; Receptor, ErbB-2; Research; Societies, Medical; Trastuzumab; United States; United States Food and Drug Administration

Topics: Animals; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Disease Models, Animal; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Homozygote; Humans; Imatinib Mesylate; Inositol Polyphosphate 5-Phosphatases; Mice; Mice, Transgenic; Mutation; Phosphatidylinositol 3-Kinases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; PTEN Phosphohydrolase; Pyloric Antrum; Pyrimidines; Real-Time Polymerase Chain Reaction; Signal Transduction; Up-Regulation

Topics: Adolescent; Adult; Aged; Animals; Antineoplastic Agents; Benzamides; Cell Degranulation; Child; Disease Models, Animal; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Killer Cells, Natural; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Transgenic; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Young Adult

Topics: Animals; Antigens, CD34; Benzamides; Cell Survival; Disease Models, Animal; DNA-Binding Proteins; Forkhead Transcription Factors; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-6; Pyrimidines; Tumor Cells, Cultured; Tumor Suppressor Protein p53

Topics: Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Imatinib Mesylate; Leukemia, Experimental; Male; Mice; Mice, Inbred C3H; Ovarian Follicle; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Spermatogenesis

Topics: Animals; Benzamides; Disease Models, Animal; Female; Imatinib Mesylate; Leukemia, Experimental; Male; Ovarian Follicle; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Spermatogenesis

Topics: Animals; Antibodies; Basal Ganglia; Benzamides; Blood Transfusion, Autologous; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Enzyme Inhibitors; Evans Blue; Gene Expression Regulation; Imatinib Mesylate; Imidazoles; Metalloendopeptidases; Mice; p38 Mitogen-Activated Protein Kinases; Piperazines; Pyridines; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Thrombin; Time Factors

Topics: Animals; Benzamides; Disease Models, Animal; Imatinib Mesylate; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; Tenascin; Vasospasm, Intracranial

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Disease Models, Animal; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Mice; Mice, SCID; Neoplasm Transplantation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Transplantation, Heterologous

Topics: Airway Remodeling; Animals; Apoptosis; Benzamides; Caspase 3; Cell Proliferation; Disease Models, Animal; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Imatinib Mesylate; Ki-67 Antigen; Lung; Phenyl Ethers; Piperazines; Platelet-Derived Growth Factor; Pregnancy; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; RNA, Messenger

Topics: Adolescent; Adult; Animals; Antibodies, Neutralizing; Becaplermin; Benzamides; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Imatinib Mesylate; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Piperazines; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, PAR-2; Receptor, Platelet-Derived Growth Factor beta; RNA Interference; Signal Transduction; Time Factors; Transfection; Tryptases; Young Adult

Topics: Animals; Apoptosis; Becaplermin; Benzamides; Cell Proliferation; Cells, Cultured; Chemotaxis; Dasatinib; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imatinib Mesylate; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Thiazoles; Time Factors

Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Benzenesulfonates; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Imatinib Mesylate; In Vitro Techniques; Indoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Piperazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib; Vascular Endothelial Growth Factor A

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Lineage; Dasatinib; Disease Models, Animal; Drug Resistance; Drug Resistance, Neoplasm; Erythrocytes; Exons; Gastrointestinal Stromal Tumors; Imatinib Mesylate; Mice; Mutation; Phenotype; Piperazines; Polycythemia; Proto-Oncogene Proteins c-kit; Pyrimidines; Thiazoles

Topics: Allergens; Animals; Benzamides; Diarrhea; Disease Models, Animal; Female; Food Hypersensitivity; Imatinib Mesylate; Intestines; Mast Cells; Mice; Ovalbumin; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction

Topics: Animals; Astrocytes; Benzamides; Blood-Brain Barrier; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; Female; Imatinib Mesylate; Inflammation; Mice; Mice, Transgenic; Motor Activity; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Receptors, Platelet-Derived Growth Factor; Recovery of Function; Spinal Cord Injuries; Treatment Outcome

Topics: Animals; Benzamides; Benzimidazoles; Case-Control Studies; Crk-Associated Substrate Protein; Disease Models, Animal; Endothelial Cells; Epidermal Growth Factor; Familial Primary Pulmonary Hypertension; Fibroblast Growth Factor 2; Gefitinib; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Mice; Monocrotaline; Myocytes, Smooth Muscle; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pulmonary Artery; Pyrimidines; Quinazolines; Quinolones; Rats; Signal Transduction

Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Carcinoembryonic Antigen; Colorectal Neoplasms; Combined Modality Therapy; Disease Models, Animal; Female; Fluorescent Antibody Technique; Humans; Imatinib Mesylate; Immunoenzyme Techniques; Mice; Mice, Nude; Piperazines; Pyrimidines; Radioimmunotherapy; Receptor, Platelet-Derived Growth Factor beta; Tissue Distribution; Transplantation, Heterologous

Topics: Animals; Antineoplastic Agents; Benzamides; Breast Neoplasms; Cats; Disease Models, Animal; Dogs; Female; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mast-Cell Sarcoma; Neoplasms; Piperazines; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Thiazoles; Transcriptome

Topics: Animals; Benzamides; Carbon; Carotid Artery, Internal; Coronary Angiography; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Gene Expression Regulation; Imatinib Mesylate; Male; Neurologic Examination; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; Subarachnoid Hemorrhage; Vasospasm, Intracranial

Topics: Animals; Benzamides; Chronic Disease; Dermis; Disease Models, Animal; Drug Therapy, Combination; Female; Fibrosis; Graft vs Host Disease; Humans; Imatinib Mesylate; Male; Mice; Mice, Inbred BALB C; Middle Aged; Piperazines; Proto-Oncogene Proteins c-abl; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Scleroderma, Systemic; Signal Transduction

Topics: Animals; Benzamides; Disease Models, Animal; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Imatinib Mesylate; Indoles; Mice; Mice, Knockout; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Serotonin; Tryptophan Hydroxylase

Topics: Animals; Benzamides; Blood-Brain Barrier; Cerebral Hemorrhage; Disease Models, Animal; Fingolimod Hydrochloride; Imatinib Mesylate; Lipopolysaccharide Receptors; Lymphocyte Function-Associated Antigen-1; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neuroimmunomodulation; Parasitemia; Piperazines; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Propylene Glycols; Pyrimidines; Sphingosine

Topics: Animals; Benzamides; Blood Pressure; Blotting, Western; Desoxycorticosterone; Disease Models, Animal; Endomyocardial Fibrosis; Fibronectins; Fibrosis; Hypertension; Imatinib Mesylate; Male; Nephrectomy; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Tenascin; Treatment Outcome

Topics: Aged; Animals; Benzamides; Disease Models, Animal; Esophageal Neoplasms; Exons; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Indoles; Male; Mice; Molecular Targeted Therapy; Mutation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sunitinib; Transplantation, Heterologous

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Bone Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunoblotting; Inhibitory Concentration 50; Phosphorylation; Piperazines; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Sarcoma, Ewing; Stem Cell Factor; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured

Topics: Actins; Animals; Benzamides; Bile Ducts; Cell Differentiation; Cell Lineage; Collagen; Desmin; Disease Models, Animal; Fibroblasts; Imatinib Mesylate; Kupffer Cells; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Phenotype; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Blotting, Western; Bone Neoplasms; Cell Division; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Nude; Microcirculation; Neoplasms, Experimental; Paclitaxel; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Radiographic Image Enhancement; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tumor Cells, Cultured

Topics: Animals; Antineoplastic Agents; Benzamides; Blotting, Western; Bone Marrow; Bone Marrow Transplantation; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Fusion Proteins, bcr-abl; Genetic Vectors; Humans; Imatinib Mesylate; Immunophenotyping; Mice; Models, Genetic; mRNA Cleavage and Polyadenylation Factors; Mutation; Myeloproliferative Disorders; Piperazines; Precipitin Tests; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Recurrence; Retroviridae; Spleen; Staurosporine; Time Factors

Topics: Administration, Oral; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Farnesyltranstransferase; Female; Fusion Proteins, bcr-abl; Imatinib Mesylate; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Nude; Mice, Transgenic; Piperazines; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Survival Rate; Tumor Cells, Cultured

Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Breast Neoplasms; Chemoprevention; Disease Models, Animal; Genes, erbB-2; Humans; Imatinib Mesylate; Mice; Mice, Transgenic; Neoplasms; Piperazines; Pyrimidines; Signal Transduction; Trastuzumab

Topics: Animals; Apoptosis; Benzamides; Cell Proliferation; Cells, Cultured; Dendritic Cells; Disease Models, Animal; Humans; Hypersensitivity, Delayed; Imatinib Mesylate; Inhibitory Concentration 50; Lymphocyte Activation; Mice; Phytohemagglutinins; Piperazines; Pyrimidines; Resting Phase, Cell Cycle; Spleen; T-Lymphocytes

Topics: Adenoma, Islet Cell; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Clinical Protocols; Cyclophosphamide; Disease Models, Animal; Endothelial Cells; Imatinib Mesylate; Indoles; Mice; Mice, Transgenic; Neovascularization, Pathologic; Pancreatic Neoplasms; Pericytes; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Remission Induction; Sunitinib

Topics: Animals; Apolipoproteins E; Base Sequence; Benzamides; Biopsy, Needle; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Imatinib Mesylate; Immunohistochemistry; Kidney Function Tests; Male; Mice; Mice, Knockout; Molecular Sequence Data; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Transforming Growth Factor beta

Topics: Animals; Antineoplastic Agents; Benzamides; Cell Line; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Molecular Structure; Mutation; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Stem Cell Factor; Survival Rate; Time Factors

Topics: Animals; Benzamides; Cell Line, Tumor; Cell Transformation, Neoplastic; Chick Embryo; Disease Models, Animal; Disease Progression; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Humans; Imatinib Mesylate; In Situ Hybridization; Oligonucleotide Array Sequence Analysis; Piperazines; Polymerase Chain Reaction; Pyrimidines; Receptor Protein-Tyrosine Kinases; Vascular Endothelial Growth Factor Receptor-2

Topics: Animals; Benzamides; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Fibroblasts; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Piperazines; Pulmonary Fibrosis; Pyrimidines; Reference Values; Treatment Outcome

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Bone Marrow Transplantation; Cell Survival; Cell Transplantation; Disease Models, Animal; Drug Resistance, Neoplasm; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Knockout; Piperazines; Pyrimidines; Survival Analysis

Topics: Animals; Benzamides; Blood Pressure; Disease Models, Animal; Heart Ventricles; Humans; Hypertension, Pulmonary; Imatinib Mesylate; Lung; Male; Mice; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Signal Transduction

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Blood-Brain Barrier; Brain Neoplasms; Caspase 3; Caspases; Cell Line, Tumor; Disease Models, Animal; Drug Evaluation, Preclinical; Glioblastoma; Imatinib Mesylate; Male; Mice; Mice, Nude; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-akt; Pyrimidines; Radiation-Sensitizing Agents; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta

Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Benzamides; Bone Marrow Cells; Cell Proliferation; Cell Transformation, Viral; Disease Models, Animal; Enzyme Activation; Fusion Proteins, bcr-abl; Gene Transfer Techniques; Imatinib Mesylate; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Transplantation; NIH 3T3 Cells; Phosphorylation; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Retroviridae; Tumor Cells, Cultured

Topics: Administration, Oral; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Phosphorylation; Piperazines; Pyrimidines; src-Family Kinases; Structure-Activity Relationship; Survival Rate; Transplantation, Heterologous; Xenograft Model Antitumor Assays

Topics: Animals; Antineoplastic Agents; Benzamides; Bile Duct Neoplasms; Cell Line, Tumor; Cholangiocarcinoma; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Imatinib Mesylate; Mice; Mice, Nude; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines

Topics: Amino Acid Sequence; Animals; Benzamides; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; Disease Models, Animal; Female; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Myeloid Progenitor Cells; Phosphotransferases; Phosphotyrosine; Piperazines; Protein Structure, Tertiary; Pyrimidines; Signal Transduction; Substrate Specificity

Topics: Animals; Benzamides; Cell Proliferation; Disease Models, Animal; Down-Regulation; Everolimus; Gastrointestinal Stromal Tumors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Imatinib Mesylate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphorylation; Piperazines; Protein Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

Topics: Animals; Benzamides; Disease Models, Animal; Fibrosis; Humans; Imatinib Mesylate; Piperazines; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyrimidines; Scleroderma, Systemic

Topics: Aged; Animals; Benzamides; Bleomycin; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Female; Fibroblasts; Fibrosis; Gene Expression; Humans; Imatinib Mesylate; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C3H; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyrimidines; RNA, Messenger; Scleroderma, Systemic; Skin; Specific Pathogen-Free Organisms

Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Disease Models, Animal; Down-Regulation; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; HeLa Cells; Histones; Humans; Imatinib Mesylate; Mice; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Transcription, Genetic; Up-Regulation

Topics: Animals; Benzamides; Blood Coagulation Factor Inhibitors; Cell Line, Tumor; Disease Models, Animal; Factor VIIa; Hyperoxia; Hypoxia; Imatinib Mesylate; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasms, Experimental; Neovascularization, Pathologic; Oxygen; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Receptor, PAR-1; Receptor, PAR-2; Retinal Neovascularization; Retinal Vessels; Signal Transduction; Thromboplastin; Time Factors

Topics: Animals; Autoimmune Diseases; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rheumatic Diseases

Topics: Animals; Becaplermin; Benzamides; Bleomycin; Disease Models, Animal; Hydroxyproline; Imatinib Mesylate; Lung; Mice; Mice, Inbred C57BL; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pulmonary Fibrosis; Pyrimidines; Random Allocation

Topics: Animals; Benzamides; Disease Models, Animal; Drug Therapy, Combination; Hypertension, Portal; Imatinib Mesylate; Immunosuppressive Agents; Ligation; Male; Mesenteric Artery, Superior; Neovascularization, Pathologic; Piperazines; Platelet-Derived Growth Factor; Portal Vein; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Signal Transduction; Sirolimus; Splanchnic Circulation; Vascular Endothelial Growth Factor A

Topics: Animals; Benzamides; Bronchi; Bronchiolitis Obliterans; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Connective Tissue Growth Factor; Disease Models, Animal; Graft Rejection; Imatinib Mesylate; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Macrophages; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sus scrofa; Time Factors; Transforming Growth Factor beta; Transplantation, Autologous; Transplantation, Homologous

Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzamides; Cell Survival; Disease Models, Animal; Imatinib Mesylate; Male; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Sertoli Cells; Spermatogenesis; Testicular Neoplasms; Testis

Topics: Animals; Benzamides; Cells, Cultured; Clarithromycin; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Erythromycin; Female; Fibroblasts; Imatinib Mesylate; Macrolides; Mice; Orosomucoid; Piperazines; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyrimidines

Topics: Adenocarcinoma; Androgen Receptor Antagonists; Angiopoietins; Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Imatinib Mesylate; Immunoglobulin Fc Fragments; Male; Neoplasm Transplantation; Neovascularization, Pathologic; Orchiectomy; Piperazines; Prostate; Prostatic Neoplasms; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor beta; Receptor, TIE-2; Receptors, Androgen; Recombinant Fusion Proteins; Stromal Cells; Xenograft Model Antitumor Assays

Topics: ADP-Ribosylation Factor 1; Animals; Benzamides; Disease Models, Animal; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Ligands; Mice; Models, Immunological; Neoplasms, Experimental; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyrimidines; Receptors, Cytokine

Topics: Animals; Benzamides; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; Fibrosis; Heart; Imatinib Mesylate; Lymphokines; Male; Mice; Mice, Knockout; Myocarditis; Myocardium; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Signal Transduction

Topics: Animals; Antineoplastic Agents; Arterial Occlusive Diseases; Benzamides; Cardiovascular Diseases; Carotid Arteries; Cell Proliferation; Cerebrovascular Disorders; Disease Models, Animal; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Genes, Neurofibromatosis 1; Imatinib Mesylate; Mice; Mice, Mutant Strains; Neurofibromatosis 1; Piperazines; Pyrimidines; Tunica Intima

Topics: Animals; Autocrine Communication; Benzamides; Blotting, Northern; Blotting, Western; Brain Neoplasms; Carrier Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique; Glioma; Humans; Imatinib Mesylate; Intermediate Filament Proteins; Mice; Mice, Inbred Strains; Mice, Nude; Nerve Tissue Proteins; Nestin; Piperazines; Platelet-Derived Growth Factor; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyrimidines; Receptor, Platelet-Derived Growth Factor alpha; Tumor Cells, Cultured

Topics: 3T3 Cells; Animals; Antineoplastic Agents; Benzamides; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Dermatofibrosarcoma; Disease Models, Animal; Gene Rearrangement; Imatinib Mesylate; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oncogene Proteins, Fusion; Phosphorylation; Piperazines; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta

Topics: Animals; Antineoplastic Agents; Benzamides; Bone Marrow Cells; Bone Marrow Transplantation; Disease Models, Animal; DNA-Binding Proteins; Fusion Proteins, bcr-abl; Imatinib Mesylate; Immediate-Early Proteins; Leukemia, Experimental; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Mice; Mice, Inbred BALB C; Milk Proteins; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Retroviridae; RNA, Messenger; Spleen; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; Survival Rate; Trans-Activators; Transduction, Genetic

Topics: Animals; Antineoplastic Agents; Benzamides; Blast Crisis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Division; Cloning, Molecular; Disease Models, Animal; Disease Progression; Fusion Proteins, bcr-abl; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Luminescent Proteins; Mice; Nuclear Pore Complex Proteins; Oncogene Proteins, Fusion; Piperazines; Proviruses; Pyrimidines; Tumor Cells, Cultured