Page last updated: 2024-09-03

imatinib mesylate and Cirrhoses, Experimental Liver

imatinib mesylate has been researched along with Cirrhoses, Experimental Liver in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, MF; Chen, TC; Kuo, WL; Lee, JF; Tsai, CN; Yu, MC1
Albanis, E; Chou, HI; Fiel, MI; Friedman, SL; Khitrov, G; Kim, Y; Zhang, W1
Barbu, V; Francoz, C; Housset, C; Hultcrantz, R; Kinnman, N; Poupon, R; Rey, C; Wendum, D1
Decosterd, LA; Ledermann, M; Neef, M; Reichen, J; Rochat, B; Saegesser, H; Schneider, V; Widmer, N1
Akahane, T; Asada, K; Fukui, H; Ikenaka, Y; Kitade, M; Kuriyama, S; Namisaki, T; Noguchi, R; Tsujimoto, T; Uemura, M; Yamazaki, M; Yanase, K; Yoshii, J; Yoshiji, H1
Groothuis, GM; Meijer, DK; Olinga, P; van de Bovenkamp, M1

Other Studies

6 other study(ies) available for imatinib mesylate and Cirrhoses, Experimental Liver

ArticleYear
Imatinib mesylate improves liver regeneration and attenuates liver fibrogenesis in CCL4-treated mice.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:2

    Topics: Animals; Apoptosis; Benzamides; Blotting, Western; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Flow Cytometry; Hepatic Stellate Cells; Imatinib Mesylate; Liver Cirrhosis, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred C3H; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Real-Time Polymerase Chain Reaction

2012
Anti-fibrotic activity and enhanced interleukin-6 production by hepatic stellate cells in response to imatinib mesylate.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:6

    Topics: Animals; Benzamides; Biomarkers; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Profiling; Hepatic Stellate Cells; Humans; Imatinib Mesylate; Interleukin-6; Liver Cirrhosis, Experimental; Male; Oligonucleotide Array Sequence Analysis; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Thioacetamide; Time Factors; Up-Regulation

2012
The myofibroblastic conversion of peribiliary fibrogenic cells distinct from hepatic stellate cells is stimulated by platelet-derived growth factor during liver fibrogenesis.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:2

    Topics: Actins; Animals; Benzamides; Bile Ducts; Cell Differentiation; Cell Lineage; Collagen; Desmin; Disease Models, Animal; Fibroblasts; Imatinib Mesylate; Kupffer Cells; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Phenotype; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2003
Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term.
    Journal of hepatology, 2006, Volume: 44, Issue:1

    Topics: Administration, Oral; Animals; Benzamides; Biomarkers; Collagen Type I; Disease Progression; Follow-Up Studies; Imatinib Mesylate; Liver Cirrhosis, Experimental; Male; Mass Spectrometry; Matrix Metalloproteinase 2; Piperazines; Procollagen; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome

2006
Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-beta with a combination of imatinib mesylate and ACE inhibitor in rats.
    International journal of molecular medicine, 2006, Volume: 17, Issue:5

    Topics: Actins; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Carbon Tetrachloride; Drug Synergism; Drug Therapy, Combination; Imatinib Mesylate; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Muscle, Smooth; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Platelet-Derived Growth Factor; Severity of Illness Index; Transforming Growth Factor beta

2006
Precision-cut fibrotic rat liver slices as a new model to test the effects of anti-fibrotic drugs in vitro.
    Journal of hepatology, 2006, Volume: 45, Issue:5

    Topics: Actins; Animals; Benzamides; Biomarkers; Collagen; Collagen Type I; Collagen Type I, alpha 1 Chain; Dexamethasone; Histocytological Preparation Techniques; Imatinib Mesylate; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Models, Animal; Pentoxifylline; Piperazines; Pyrimidines; Rats; Rats, Wistar

2006