Page last updated: 2024-11-04

imatinib and Neoplasms

imatinib has been researched along with Neoplasms in 10 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Some of them showed anti-cancer activities along with a number of reference compounds tested."1.37Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents. ( Dubey, PK; Pal, M; Piedrafita, FJ; Rajitha, C; Sunku, V; Veeramaneni, VR, 2011)
"Genetically defined cancer subsets, irrespective of tissue type, predict response to kinase inhibitors, and provide an important preclinical model to guide early clinical applications of novel targeted inhibitors."1.34Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. ( Archibald, H; Dowell, L; Drew, L; Erlander, MG; Gray, NS; Greninger, P; Haber, DA; Hanke, JH; Iafrate, AJ; Lamb, J; Lee, D; Ma, XJ; Maheswaran, S; McDermott, U; Montagut, C; Njauw, CN; Raudales, R; Rothenberg, SM; Settleman, J; Sharma, SV; Sordella, R; Supko, JG; Tam, A; Tsao, H; Ulkus, LE, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Carter, TA1
Wodicka, LM1
Shah, NP1
Velasco, AM1
Fabian, MA1
Treiber, DK1
Milanov, ZV1
Atteridge, CE1
Biggs, WH1
Edeen, PT1
Floyd, M1
Ford, JM1
Grotzfeld, RM1
Herrgard, S1
Insko, DE1
Mehta, SA1
Patel, HK1
Pao, W1
Sawyers, CL1
Varmus, H1
Zarrinkar, PP1
Lockhart, DJ1
McDermott, U1
Sharma, SV1
Dowell, L1
Greninger, P1
Montagut, C1
Lamb, J1
Archibald, H1
Raudales, R1
Tam, A1
Lee, D1
Rothenberg, SM1
Supko, JG1
Sordella, R1
Ulkus, LE1
Iafrate, AJ1
Maheswaran, S1
Njauw, CN1
Tsao, H1
Drew, L1
Hanke, JH1
Ma, XJ1
Erlander, MG1
Gray, NS2
Haber, DA1
Settleman, J1
Bikker, JA1
Brooijmans, N1
Wissner, A1
Mansour, TS1
Rajitha, C1
Dubey, PK1
Sunku, V1
Piedrafita, FJ1
Veeramaneni, VR1
Pal, M1
Corradi, V1
Mancini, M1
Santucci, MA1
Carlomagno, T1
Sanfelice, D1
Mori, M1
Vignaroli, G1
Falchi, F1
Manetti, F1
Radi, M1
Botta, M1
Kim, HG1
Tan, L1
Weisberg, EL1
Liu, F1
Canning, P1
Choi, HG1
Ezell, SA1
Wu, H1
Zhao, Z1
Wang, J1
Mandinova, A1
Griffin, JD1
Bullock, AN1
Liu, Q1
Lee, SW1
Huang, TL1
Mayence, A1
Vanden Eynde, JJ1
Li, Y1
Lu, X1
Ren, X1
Ding, K1
Gao, C1
Li, B1
Zhang, B1
Sun, Q1
Li, L1
Li, X1
Chen, C1
Tan, C1
Liu, H1
Jiang, Y1
Joshi, H1
Patil, V1
Tilekar, K1
Upadhyay, N1
Gota, V1
Ramaa, CS1

Reviews

2 reviews available for imatinib and Neoplasms

ArticleYear
Some non-conventional biomolecular targets for diamidines. A short survey.
    Bioorganic & medicinal chemistry, 2014, Apr-01, Volume: 22, Issue:7

    Topics: Amidines; Animals; Diabetes Mellitus, Type 2; DNA; Enzymes; Humans; Hypertension; Ion Channels; Myot

2014
Some non-conventional biomolecular targets for diamidines. A short survey.
    Bioorganic & medicinal chemistry, 2014, Apr-01, Volume: 22, Issue:7

    Topics: Amidines; Animals; Diabetes Mellitus, Type 2; DNA; Enzymes; Humans; Hypertension; Ion Channels; Myot

2014
Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.
    Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8

    Topics: Amino Acid Sequence; Animals; Discoidin Domain Receptors; Drug Discovery; Humans; Inflammation; Liga

2015
Small molecule discoidin domain receptor kinase inhibitors and potential medical applications.
    Journal of medicinal chemistry, 2015, Apr-23, Volume: 58, Issue:8

    Topics: Amino Acid Sequence; Animals; Discoidin Domain Receptors; Drug Discovery; Humans; Inflammation; Liga

2015

Other Studies

8 other studies available for imatinib and Neoplasms

ArticleYear
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Aug-02, Volume: 102, Issue:31

    Topics: Aminoquinolines; Aniline Compounds; Cell Line; Drug Resistance, Neoplasm; ErbB Receptors; Humans; In

2005
Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Aug-02, Volume: 102, Issue:31

    Topics: Aminoquinolines; Aniline Compounds; Cell Line; Drug Resistance, Neoplasm; ErbB Receptors; Humans; In

2005
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-11, Volume: 104, Issue:50

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor

2007
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-11, Volume: 104, Issue:50

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor

2007
Kinase domain mutations in cancer: implications for small molecule drug design strategies.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Amino Acid Sequence; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Molecular Sequen

2009
Kinase domain mutations in cancer: implications for small molecule drug design strategies.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Amino Acid Sequence; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Molecular Sequen

2009
Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Drug Screening Assays, Antitumor; Huma

2011
Synthesis and pharmacological evaluations of novel 2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as a new class of anti-cancer agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Antineoplastic Agents; Benzene Derivatives; Cell Line, Tumor; Drug Screening Assays, Antitumor; Huma

2011
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.
    Bioorganic & medicinal chemistry letters, 2011, Nov-15, Volume: 21, Issue:22

    Topics: 14-3-3 Proteins; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Line; Drug Desig

2011
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.
    Bioorganic & medicinal chemistry letters, 2011, Nov-15, Volume: 21, Issue:22

    Topics: 14-3-3 Proteins; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Cell Line; Drug Desig

2011
Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
    ACS chemical biology, 2013, Oct-18, Volume: 8, Issue:10

    Topics: Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Discoidin Domain Receptor 1; Drug Disc

2013
Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor.
    ACS chemical biology, 2013, Oct-18, Volume: 8, Issue:10

    Topics: Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Discoidin Domain Receptor 1; Drug Disc

2013
Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.
    Bioorganic & medicinal chemistry, 2015, Apr-15, Volume: 23, Issue:8

    Topics: Acridines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; DNA; Humans; Intercal

2015
Synthesis and biological evaluation of benzimidazole acridine derivatives as potential DNA-binding and apoptosis-inducing agents.
    Bioorganic & medicinal chemistry, 2015, Apr-15, Volume: 23, Issue:8

    Topics: Acridines; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; DNA; Humans; Intercal

2015
Benzylidene thiazolidinediones: Synthesis, in vitro investigations of antiproliferative mechanisms and in vivo efficacy determination in combination with Imatinib.
    Bioorganic & medicinal chemistry letters, 2020, 12-01, Volume: 30, Issue:23

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylide

2020
Benzylidene thiazolidinediones: Synthesis, in vitro investigations of antiproliferative mechanisms and in vivo efficacy determination in combination with Imatinib.
    Bioorganic & medicinal chemistry letters, 2020, 12-01, Volume: 30, Issue:23

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzylide

2020