Page last updated: 2024-11-04

imatinib and Experimental Neoplasms

imatinib has been researched along with Experimental Neoplasms in 3 studies

Research Excerpts

ExcerptRelevanceReference
" A pharmacokinetic study revealed that 18a had over 4 h of half-life and 24% bioavailability in rats."1.43Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le ( Chen, C; Hu, Z; Liang, X; Liu, J; Liu, Q; Liu, X; Lv, F; Qi, S; Qi, Z; Wang, A; Wang, B; Wang, L; Wang, W; Zhang, S; Zhao, Z; Zou, F, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liang, X1
Liu, X4
Wang, B3
Zou, F1
Wang, A3
Qi, S2
Chen, C3
Zhao, Z1
Wang, W6
Qi, Z2
Lv, F1
Hu, Z3
Wang, L3
Zhang, S2
Liu, Q4
Liu, J3
Wang, Q1
Liu, F1
Yan, XE1
Jiang, Z2
Ren, T2
Yun, CH1
Hu, C1
Wu, H1
Zhang, Y1
Wang, J1
Huang, T1
Li, L1
Xia, R1
Ge, J1

Other Studies

3 other studies available for imatinib and Experimental Neoplasms

ArticleYear
Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Le
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell

2016
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Acrylamides; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Proliferation; Dose-Respons

2018
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants includi
    European journal of medicinal chemistry, 2018, Dec-05, Volume: 160

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferat

2018