iguratimod has been researched along with Disease Models, Animal in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 5 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ge, Y; Tian, J; Wang, S; Yang, J; Yu, J | 1 |
| Dai, X; Fang, X; Jin, L; Li, M; Li, X; Tao, J; Wang, Y; Xia, Y | 1 |
| Ding, J; Fu, X; Han, Q; Liang, Q; Xie, R; Yang, F; Zhang, K; Zheng, Z; Zhu, P | 1 |
| Cong, S; Luo, L; Meng, Y; Shi Nu Er Xia Ti, TB; Sun, J; Wang, L | 1 |
| Li, D; Liang, Y; Qu, Z; Shao, S; Xu, Y; Yin, S; Zhang, Y; Zhou, D | 1 |
| Guo, FJ; Guo, JC; Huang, JM; Jing, XZ; Sun, Y; Wu, YX; Xiang, W; Ye, YP; Yu, SY; Zhang, P | 1 |
| Huang, XL; Huang, ZM; Jiang, XP; Miao, L; Tang, L; Wang, SC; Xie, W; Yang, ZP | 1 |
| Cheng, Y; Huang, C; Mu, B; Zhao, L; Zhou, R | 1 |
| Bao, C; Chen, S; Dai, D; Du, F; Fu, Q; Huang, X; Yan, Q | 1 |
| Hara, M | 1 |
1 review(s) available for iguratimod and Disease Models, Animal
| Article | Year |
|---|---|
[T-614 for therapy of rheumatoid arthritis].
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Benzopyrans; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Cytokines; Depression, Chemical; Disease Models, Animal; Humans; Immunoglobulins; Sulfonamides | 2005 |
9 other study(ies) available for iguratimod and Disease Models, Animal
| Article | Year |
|---|---|
Effects of iguratimod on inflammatory factors and apoptosis of submandibular gland epithelial cells in NOD mice.
Topics: Animals; Apoptosis; Disease Models, Animal; Inflammation; Mice; Mice, Inbred NOD; Sjogren's Syndrome; Submandibular Gland | 2023 |
Iguratimod ameliorates nephritis by modulating the Th17/Treg paradigm in pristane-induced lupus.
Topics: Animals; Antibodies, Antinuclear; Arthritis, Rheumatoid; Chromones; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Humans; Immunoglobulins; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred BALB C; Proteinuria; Sulfonamides; T-Lymphocytes, Regulatory; Terpenes; Th17 Cells | 2021 |
Iguratimod reduces B-cell secretion of immunoglobulin to play a protective role in interstitial lung disease.
Topics: Animals; B-Lymphocytes; Bleomycin; Chromones; Disease Models, Animal; Humans; Immunoglobulins; Lung; Lung Diseases, Interstitial; Mice; Sulfonamides | 2021 |
T-614 attenuates knee osteoarthritis via regulating Wnt/β-catenin signaling pathway.
Topics: Animals; Benzopyrans; beta Catenin; Cartilage, Articular; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Glycogen Synthase Kinase 3 beta; Interleukin-6; Matrix Metalloproteinase 13; Osteoarthritis, Knee; Papain; Rats; Sulfonamides; Tumor Necrosis Factor-alpha; Wnt Signaling Pathway | 2021 |
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Topics: A549 Cells; Actins; Animals; Bleomycin; Cadherins; Chromones; Collagen; Disease Models, Animal; Epithelial-Mesenchymal Transition; Humans; Matrix Metalloproteinase 2; Mice; NF-kappa B; Pneumonia; Pulmonary Fibrosis; Signal Transduction; Sulfonamides; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Vimentin | 2021 |
Iguratimod prevents ovariectomy‑induced bone loss and suppresses osteoclastogenesis via inhibition of peroxisome proliferator‑activated receptor‑γ.
Topics: Animals; Bone Resorption; Cells, Cultured; Chromones; Disease Models, Animal; Female; Gene Expression Regulation; Genes, fos; Mice; NFATC Transcription Factors; Osteoclasts; Ovariectomy; Postmenopause; PPAR gamma; Protective Agents; RANK Ligand; Sulfonamides; X-Ray Microtomography | 2017 |
Iguratimod ameliorates inflammatory responses by modulating the Th17/Treg paradigm in dextran sulphate sodium-induced murine colitis.
Topics: Animals; Chromones; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Evaluation, Preclinical; Gene Expression Regulation; Immunosuppressive Agents; Inflammatory Bowel Diseases; Interleukins; Intestinal Mucosa; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Random Allocation; Specific Pathogen-Free Organisms; Spleen; Sulfonamides; T-Lymphocytes, Regulatory; Th17 Cells; Transcription Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2018 |
Iguratimod ameliorates bleomycin-induced alveolar inflammation and pulmonary fibrosis in mice by suppressing expression of matrix metalloproteinase-9.
Topics: Airway Remodeling; Animals; Anti-Inflammatory Agents; Bleomycin; Chromones; Collagen; Cytokines; Disease Models, Animal; Inflammation Mediators; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice, Inbred C57BL; Pneumonia; Pulmonary Alveoli; Pulmonary Fibrosis; Sulfonamides | 2019 |
Prevention of immune nephritis by the small molecular weight immunomodulator iguratimod in MRL/lpr mice.
Topics: Animals; Biomarkers; Chromones; Cytokines; Cytotoxicity, Immunologic; Disease Models, Animal; Female; Immunologic Factors; Lupus Nephritis; Lymphocyte Subsets; Mice; Mice, Inbred MRL lpr; Molecular Weight; Sulfonamides | 2014 |