Page last updated: 2024-09-03

iguratimod and Bone Loss, Osteoclastic

iguratimod has been researched along with Bone Loss, Osteoclastic in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ebina, K; Etani, Y; Goshima, A; Hirao, M; Kanamoto, T; Miura, T; Miyama, A; Nakata, K; Okamura, G; Oyama, S; Takami, K; Yoshikawa, H1
Guo, FJ; Guo, JC; Huang, JM; Jing, XZ; Sun, Y; Wu, YX; Xiang, W; Ye, YP; Yu, SY; Zhang, P1
Feng, X; Gan, K; Tan, W; Wang, F; Xu, L; Yang, L; Zhang, M; Zhang, Q1
Peng, G; Sun, Y; Wang, BY; Wu, YX; Ye, DW; Yu, SY; Zhang, P1

Other Studies

4 other study(ies) available for iguratimod and Bone Loss, Osteoclastic

ArticleYear
Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro.
    Journal of bone and mineral metabolism, 2021, Volume: 39, Issue:4

    Topics: Alkaline Phosphatase; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Marrow Cells; Bone Resorption; Calcification, Physiologic; Cell Count; Cell Line; Chromones; Dexamethasone; Down-Regulation; Glucocorticoids; Male; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Sulfonamides; Up-Regulation

2021
Iguratimod prevents ovariectomy‑induced bone loss and suppresses osteoclastogenesis via inhibition of peroxisome proliferator‑activated receptor‑γ.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Animals; Bone Resorption; Cells, Cultured; Chromones; Disease Models, Animal; Female; Gene Expression Regulation; Genes, fos; Mice; NFATC Transcription Factors; Osteoclasts; Ovariectomy; Postmenopause; PPAR gamma; Protective Agents; RANK Ligand; Sulfonamides; X-Ray Microtomography

2017
Iguratimod (T-614) suppresses RANKL-induced osteoclast differentiation and migration in RAW264.7 cells via NF-κB and MAPK pathways.
    International immunopharmacology, 2016, Volume: 35

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Resorption; Cell Differentiation; Cell Movement; Chromones; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Proto-Oncogene Proteins c-fos; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Sulfonamides

2016
Anti-rheumatic drug iguratimod (T-614) alleviates cancer-induced bone destruction via down-regulating interleukin-6 production in a nuclear factor-κB-dependent manner.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2016, Volume: 36, Issue:5

    Topics: Animals; Apoptosis; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Carcinogenesis; Cell Movement; Cell Proliferation; Chromones; Female; Humans; Interleukin-6; MCF-7 Cells; Neoplasm Invasiveness; Rats; Sulfonamides; Transcription Factor RelA

2016