Page last updated: 2024-10-29

ifosfamide and Urinary Tract Diseases

ifosfamide has been researched along with Urinary Tract Diseases in 17 studies

Research Excerpts

ExcerptRelevanceReference
"Two trials using ifosfamide-based combination chemotherapy for advanced soft-tissue sarcoma have been completed."7.68Ifosfamide combination regimens for soft-tissue sarcoma. ( Bell, DR; Dalley, D; Levi, J; Simes, RJ; Stuart-Harris, R; Wiltshaw, E, 1993)
"The response of ifosfamide-based chemotherapeutic regimens was retrospectively analyzed in adult patients with advanced soft-tissue sarcoma who were treated at the West German Tumor Center, Essen, between 1978 and 1990."7.68Ifosfamide in the treatment of soft-tissue sarcomas: experience at the West German Tumor Center, Essen. ( Kellner, R; Schütte, J; Seeber, S, 1993)
"Ifosfamide is a cyclophosphamide analogue synthesized in the 1960s with antineoplastic activity demonstrated in early broad-ranging phase I studies conducted in Germany in the 1970s."6.38Ifosfamide and mesna in epithelial ovarian carcinoma. ( Sutton, G, 1993)
"In a phase II trial of ifosfamide 2 g/m2 days 1 to 4 with mesna uroprotection in 124 patients who had previously failed treatment for sarcomas, 3% achieved a complete response (CR), and 18% had a CR or partial response (PR)."5.06Dana-Farber Cancer Institute studies in advanced sarcoma. ( Antman, KH; Elias, A, 1990)
"Two trials using ifosfamide-based combination chemotherapy for advanced soft-tissue sarcoma have been completed."3.68Ifosfamide combination regimens for soft-tissue sarcoma. ( Bell, DR; Dalley, D; Levi, J; Simes, RJ; Stuart-Harris, R; Wiltshaw, E, 1993)
"The response of ifosfamide-based chemotherapeutic regimens was retrospectively analyzed in adult patients with advanced soft-tissue sarcoma who were treated at the West German Tumor Center, Essen, between 1978 and 1990."3.68Ifosfamide in the treatment of soft-tissue sarcomas: experience at the West German Tumor Center, Essen. ( Kellner, R; Schütte, J; Seeber, S, 1993)
"Ifosfamide was administered by intravenous drip infusion at a daily dose of 2 g/m2 for 5 consecutive days, and mesna was intravenously administered at 20% of the ifosfamide dose, three times daily for 5 consecutive days."2.67Placebo-controlled double-blind comparative study on the preventive efficacy of mesna against ifosfamide-induced urinary disorders. ( Fukuoka, M; Furuse, K; Ikegami, H; Kawahara, M; Kodama, N; Masuda, N; Nakamura, S; Negoro, S; Nishio, H; Ohnoshi, T, 1991)
"Ifosfamide is a cyclophosphamide analogue synthesized in the 1960s with antineoplastic activity demonstrated in early broad-ranging phase I studies conducted in Germany in the 1970s."2.38Ifosfamide and mesna in epithelial ovarian carcinoma. ( Sutton, G, 1993)
"One hundred and forty-six patients with advanced malignant disease were treated with 6 different dosage schedules of ifosfamide (IFX)."1.28Ifosfamide and mesna in the treatment of malignant disease mesna as urothelial protector. ( Falkson, CI; Falkson, G; Falkson, HC, 1989)
"Ifosfamide was given to 61 patients with malignant solid tumors diagnosed before the age of 21 years."1.27Phase II trial of ifosfamide in children with malignant solid tumors. ( Douglass, EC; Etcubanas, E; Green, AA; Hayes, FA; Horowitz, ME; Meyer, WH; Pratt, CB; Thompson, EI; Wilimas, JA, 1987)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's8 (47.06)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lawson, M1
Vasilaras, A1
De Vries, A1
Mactaggart, P1
Nicol, D1
Brock, N4
Pohl, J3
Stekar, J3
Sutton, G1
Cerny, T1
Stuart-Harris, R1
Dalley, D1
Bell, DR1
Levi, J1
Simes, RJ1
Wiltshaw, E1
Schütte, J1
Kellner, R1
Seeber, S1
Niemeyer, U1
Scheffler, G1
Munshi, NC1
Loehrer, PJ2
Williams, SD1
Fukuoka, M1
Negoro, S1
Masuda, N1
Furuse, K1
Kawahara, M1
Kodama, N1
Ikegami, H1
Nakamura, S1
Nishio, H1
Ohnoshi, T1
Antman, KH1
Elias, A1
Holoye, PY1
Glisson, BS1
Lee, JS1
Dhingra, HM1
Murphy, WK1
Umsawasdi, T1
Levy, JK1
Jeffries, D1
Raber, MN1
Hong, WK1
Falkson, CI1
Falkson, HC1
Falkson, G1
Ishikawa, M1
Takayanagi, Y1
Sasaki, K1
Pratt, CB1
Horowitz, ME1
Meyer, WH1
Etcubanas, E1
Thompson, EI1
Douglass, EC1
Wilimas, JA1
Hayes, FA1
Green, AA1
Einhorn, LH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase Ⅱ Randomized Clinical Trial Comparing Vinorelbine-ifosfamide With Gefitinib as Third-line Treatment in Advanced EGFR Gene Mutation Negative Non-small Cell Lung Cancer Patients[NCT01749072]Phase 2120 participants (Anticipated)Interventional2012-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for ifosfamide and Urinary Tract Diseases

ArticleYear
Urological implications of cyclophosphamide and ifosfamide.
    Scandinavian journal of urology and nephrology, 2008, Volume: 42, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Transitional Cell; Cyclophosphamide; Cystitis; Humans; Ifosfamide;

2008
Ifosfamide and mesna in epithelial ovarian carcinoma.
    Gynecologic oncology, 1993, Volume: 51, Issue:1

    Topics: Carcinoma; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Female; Humans;

1993
Uroprotection in patients receiving cyclophosphamide and ifosfamide.
    Cancer treatment and research, 1991, Volume: 58

    Topics: Acrolein; Cyclophosphamide; Humans; Ifosfamide; Sulfhydryl Compounds; Urinary Tract; Urologic Diseas

1991

Trials

2 trials available for ifosfamide and Urinary Tract Diseases

ArticleYear
Placebo-controlled double-blind comparative study on the preventive efficacy of mesna against ifosfamide-induced urinary disorders.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:5

    Topics: Adult; Aged; Double-Blind Method; Female; Hematuria; Humans; Ifosfamide; Lung Neoplasms; Male; Mesna

1991
Dana-Farber Cancer Institute studies in advanced sarcoma.
    Seminars in oncology, 1990, Volume: 17, Issue:1 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation

1990

Other Studies

12 other studies available for ifosfamide and Urinary Tract Diseases

ArticleYear
The development of mesna for the inhibition of urotoxic side effects of cyclophosphamide, ifosfamide, and other oxazaphosphorine cytostatics.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 74

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cystitis; Erythrocyte Count; Ifosfamide; Mercaptoe

1980
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention. 2. Comparative study on the uroprotective efficacy of thiols and other sulfur compounds.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:11

    Topics: Animals; Cyclophosphamide; Cystitis; Female; Hemorrhage; Ifosfamide; Kinetics; Male; Rats; Rats, Inb

1981
Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--I. Experimental studies on the urotoxicity of alkylating compounds.
    European journal of cancer, 1981, Volume: 17, Issue:6

    Topics: Alkylating Agents; Animals; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Female; If

1981
High dose ifosfamide with mesna uroprotection.
    Pathologie-biologie, 1993, Volume: 41, Issue:1

    Topics: Drug Therapy, Combination; Humans; Ifosfamide; Lymphoma; Mesna; Urologic Diseases

1993
Ifosfamide combination regimens for soft-tissue sarcoma.
    Cancer chemotherapy and pharmacology, 1993, Volume: 31 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Etoposide; Fem

1993
Ifosfamide in the treatment of soft-tissue sarcomas: experience at the West German Tumor Center, Essen.
    Cancer chemotherapy and pharmacology, 1993, Volume: 31 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Dru

1993
Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:4

    Topics: Acrolein; Aldehydes; Animals; Cyclophosphamide; Cystitis; Female; Ifosfamide; Inactivation, Metaboli

1979
Ifosfamide with mesna uroprotection in the management of lung cancer.
    American journal of clinical oncology, 1990, Volume: 13, Issue:2

    Topics: Aged; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Female; Humans

1990
Ifosfamide and mesna in the treatment of malignant disease mesna as urothelial protector.
    Investigational new drugs, 1989, Volume: 7, Issue:2-3

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Ifosfamide; Male; Mercaptoethanol; Mesna; Mi

1989
Influence of buthionine sulfoximine on the lethality of ifosfamide and ifosfamide-induced urotoxicity in mice.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cysteamine; Glutathione; Ifosfamide; Liver; Male; Methionine Sulfox

1989
Phase II trial of ifosfamide in children with malignant solid tumors.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Drug Eva

1987
Ifosfamide chemotherapy for pancreatic carcinoma.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18 Suppl 2

    Topics: Acetylcysteine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfam

1986