ifosfamide has been researched along with Seminoma in 33 studies
Seminoma: A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of single agent carboplatin chemotherapy in patients with metastatic seminoma based on the data from two randomised trials." | 9.11 | Metastatic seminoma treated with either single agent carboplatin or cisplatin-based combination chemotherapy: a pooled analysis of two randomised trials. ( Bokemeyer, C; Clemm, C; Gerl, A; Hartmann, JT; Horwich, A; Kanz, L; Kollmannsberger, C; Meisner, C; Oliver, T; Rückerl, CP; Schmoll, HJ; Stenning, S, 2004) |
| "This prospective phase II study assesses the clinical efficacy and complications of a treatment regimen comprising combination chemotherapy with carboplatin and ifosfamide and selective consolidation in advanced seminoma." | 9.08 | Carboplatin and ifosfamide and selective consolidation in advanced seminoma. ( Amato, RJ; Banks, M; Ellerhorst, J; Logothetis, CJ, 1995) |
| "To study the role of single agent carboplatin chemotherapy in patients with metastatic seminoma based on the data from two randomised trials." | 5.11 | Metastatic seminoma treated with either single agent carboplatin or cisplatin-based combination chemotherapy: a pooled analysis of two randomised trials. ( Bokemeyer, C; Clemm, C; Gerl, A; Hartmann, JT; Horwich, A; Kanz, L; Kollmannsberger, C; Meisner, C; Oliver, T; Rückerl, CP; Schmoll, HJ; Stenning, S, 2004) |
| "This prospective phase II study assesses the clinical efficacy and complications of a treatment regimen comprising combination chemotherapy with carboplatin and ifosfamide and selective consolidation in advanced seminoma." | 5.08 | Carboplatin and ifosfamide and selective consolidation in advanced seminoma. ( Amato, RJ; Banks, M; Ellerhorst, J; Logothetis, CJ, 1995) |
| "Since 1980, 73 patients with advanced testicular cancer have been treated with chemotherapy and 43 patients received post-chemotherapy (salvage) surgery." | 2.69 | [Results of chemotherapy and salvage surgery for advanced testicular cancer]. ( Kinouchi, T; Kotake, T; Kuroda, M; Maeda, O; Meguro, N; Miki, T; Saiki, S; Usami, M, 1999) |
| "In relapsed germ cell tumors, salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) is a well-established regimen for patients with favorable features such as a primary testicular tumor and prior complete remission (CR) after the initial chemotherapy." | 1.37 | Salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) in relapsed or cisplatin-refractory germ cell tumors. ( Kang, WK; Lee, J; Lee, S; Lim, HY; Park, JO; Park, S; Park, SH; Park, YS, 2011) |
| "The amazing results in testicular cancer were possible by consistent performance of clinical trials." | 1.34 | [Inductive systemic therapy of urological tumors with curative intent]. ( Krege, S; Rübben, H; vom Dorp, F, 2007) |
| "We report a case of relapsed testicular tumor complicated by neutropenic enterocolitis during high dose chemotherapy with PBSCT." | 1.30 | [A case of neutropenic enterocolitis in high dose chemotherapy with peripheral blood stem cell transplantation for relapsed testicular tumor]. ( Haga, N; Honda, K; Itoh, M; Muraki, O; Ohto, H; Tsuruya, Y; Yamaguchi, O, 1998) |
| "For giant testicular tumor with extensive invasion to the spermatic cord, initial chemotherapy followed by surgical resection appears to be a better management." | 1.30 | [Two cases of giant testicular tumor with widespread extension to the spermatic cord: usefulness of upfront chemotherapy]. ( Fukui, I; Izutani, T; Kin, T; Kitsukawa, S; Maeda, Y; Shishido, T; Yonese, J, 1999) |
| " Poor performance status and prior radiotherapy were risk factors for fatal adverse effects." | 1.30 | [Treatment of advanced testicular cancer and toxicity of chemotherapy]. ( Kawakita, M; Matsuda, T; Terachi, T; Yoshida, O, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (36.36) | 18.2507 |
| 2000's | 11 (33.33) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnet, E | 1 |
| Tartas, S | 1 |
| Lazareth, A | 1 |
| Jaouen, A | 1 |
| Tamarelle, B | 1 |
| You, B | 1 |
| Maillet, D | 1 |
| Fizazi, K | 1 |
| Delva, R | 1 |
| Caty, A | 1 |
| Chevreau, C | 1 |
| Kerbrat, P | 1 |
| Rolland, F | 1 |
| Priou, F | 1 |
| Geoffrois, L | 2 |
| Rixe, O | 1 |
| Beuzeboc, P | 1 |
| Malhaire, JP | 1 |
| Culine, S | 1 |
| Aubelle, MS | 1 |
| Laplanche, A | 1 |
| Inai, H | 1 |
| Kawai, K | 2 |
| Kojima, T | 1 |
| Joraku, A | 1 |
| Shimazui, T | 2 |
| Yamauchi, A | 1 |
| Miyagawa, T | 1 |
| Endo, T | 1 |
| Fukuhara, Y | 1 |
| Miyazaki, J | 1 |
| Uchida, K | 1 |
| Nishiyama, H | 1 |
| Jeong, Y | 1 |
| Cheon, J | 1 |
| Kim, TO | 1 |
| Lim, DH | 1 |
| Lee, S | 2 |
| Cho, YM | 1 |
| Hong, JH | 1 |
| Lee, JL | 1 |
| Joly, C | 1 |
| Deblock, M | 1 |
| Desandes, E | 1 |
| Zschäbitz, S | 1 |
| Lasitschka, F | 1 |
| Hadaschik, B | 1 |
| Hofheinz, RD | 1 |
| Jentsch-Ullrich, K | 1 |
| Grüner, M | 1 |
| Jäger, D | 1 |
| Grüllich, C | 1 |
| Mesa, H | 1 |
| Rawal, A | 1 |
| Rezcallah, A | 1 |
| Iwamoto, C | 1 |
| Niehans, GA | 1 |
| Druck, P | 1 |
| Gupta, P | 1 |
| Sneag, DB | 1 |
| Ramaiya, N | 1 |
| O'Regan, KN | 1 |
| Jagannathan, JP | 1 |
| Hornick, JL | 1 |
| Ho, VT | 1 |
| Hayes, JH | 1 |
| Braquet, P | 1 |
| Chapelle, A | 1 |
| Jorgensen, C | 1 |
| Pers, YM | 1 |
| Park, S | 1 |
| Lee, J | 1 |
| Park, SH | 1 |
| Park, JO | 1 |
| Kang, WK | 1 |
| Park, YS | 1 |
| Lim, HY | 1 |
| Lorch, A | 1 |
| Kleinhans, A | 1 |
| Kramar, A | 1 |
| Kollmannsberger, CK | 1 |
| Hartmann, JT | 2 |
| Bokemeyer, C | 2 |
| Rick, O | 2 |
| Beyer, J | 2 |
| Porcaro, AB | 1 |
| Antoniolli, SZ | 1 |
| Maffei, N | 1 |
| Beltrami, P | 1 |
| Bassetto, MA | 1 |
| Curti, P | 1 |
| Kita, M | 1 |
| Sasaki, Y | 1 |
| Okuyama, M | 1 |
| Saga, Y | 1 |
| Hashimoto, H | 1 |
| Kaneko, S | 1 |
| Yachiku, S | 1 |
| Tokumitsu, M | 1 |
| Inada, F | 1 |
| Ishida, H | 1 |
| Kollmannsberger, C | 1 |
| Stenning, S | 1 |
| Horwich, A | 1 |
| Clemm, C | 1 |
| Gerl, A | 1 |
| Meisner, C | 1 |
| Rückerl, CP | 1 |
| Schmoll, HJ | 1 |
| Kanz, L | 1 |
| Oliver, T | 1 |
| Lamerz, R | 1 |
| Stieber, P | 1 |
| Bedano, PM | 1 |
| Bonnin, J | 1 |
| Einhorn, LH | 3 |
| Shigemura, K | 1 |
| Tanaka, K | 1 |
| Hara, I | 1 |
| Muramaki, M | 1 |
| Arakawa, S | 1 |
| Fujisawa, M | 1 |
| Takaoka, E | 1 |
| Naoi, M | 1 |
| Mori, K | 1 |
| Minami, M | 1 |
| Akaza, H | 1 |
| Fléchon, A | 2 |
| Droz, JP | 3 |
| vom Dorp, F | 1 |
| Krege, S | 1 |
| Rübben, H | 1 |
| Zhou, JF | 1 |
| Bai, CM | 1 |
| Yang, D | 1 |
| Chen, SC | 1 |
| Onishi, T | 1 |
| Nakano, S | 1 |
| Yanagawa, M | 1 |
| Sugimura, Y | 1 |
| Tochigi, H | 1 |
| Kawamura, J | 1 |
| Fosså, SD | 1 |
| Stoter, G | 1 |
| Kaye, SB | 1 |
| Vermeylen, K | 1 |
| Sylvester, R | 1 |
| Amato, RJ | 1 |
| Ellerhorst, J | 1 |
| Banks, M | 1 |
| Logothetis, CJ | 1 |
| Oliver, RT | 1 |
| Miller, KD | 1 |
| Loehrer, PJ | 1 |
| Gonin, R | 1 |
| Muraki, O | 1 |
| Itoh, M | 1 |
| Haga, N | 1 |
| Tsuruya, Y | 1 |
| Honda, K | 1 |
| Yamaguchi, O | 1 |
| Ohto, H | 1 |
| Kingreen, D | 1 |
| Schwella, N | 1 |
| Krusch, A | 1 |
| Schleicher, J | 1 |
| Kirsch, A | 1 |
| Huhn, D | 1 |
| Siegert, W | 1 |
| Kin, T | 1 |
| Kitsukawa, S | 1 |
| Shishido, T | 1 |
| Maeda, Y | 1 |
| Izutani, T | 1 |
| Yonese, J | 1 |
| Fukui, I | 1 |
| Biron, P | 1 |
| Philip, I | 1 |
| Blay, JY | 1 |
| Ganjoo, KN | 1 |
| Chan, RJ | 1 |
| Sharma, M | 1 |
| Saiki, S | 1 |
| Meguro, N | 1 |
| Maeda, O | 1 |
| Kinouchi, T | 1 |
| Kuroda, M | 1 |
| Usami, M | 1 |
| Kotake, T | 1 |
| Miki, T | 1 |
| Kawakita, M | 1 |
| Matsuda, T | 1 |
| Terachi, T | 1 |
| Yoshida, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Centre Phase II Study Using Carboplatin AUC-10 for Metastatic Seminoma With IGCCCG Good Prognosis Disease-Therapy Directed by Initial Metabolic Response on PET-CT[NCT02272816] | Phase 2 | 48 participants (Actual) | Interventional | 2012-02-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants progression free 2 years after registration. (NCT02272816)
Timeframe: 2 years
| Intervention | Participants (Count of Participants) |
|---|---|
| Carboplatin AUC-10 | 46 |
4 reviews available for ifosfamide and Seminoma
| Article | Year |
|---|---|
Management of testicular seminoma advanced disease. Report on 14 cases and review of the literature.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin | 2002 |
[Pulmonary rhabdomyosarcoma generated during treatment of testicular tumor].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Embryonal; Cisplatin; Combined Mod | 2003 |
[Testis germ cell tumours: which chemotherapy, for which patients?].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplasti | 2007 |
Future trials in germ cell malignancy (GCM) of the testis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineopl | 1997 |
5 trials available for ifosfamide and Seminoma
| Article | Year |
|---|---|
Sequential versus single high-dose chemotherapy in patients with relapsed or refractory germ cell tumors: long-term results of a prospective randomized trial.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 2012 |
Metastatic seminoma treated with either single agent carboplatin or cisplatin-based combination chemotherapy: a pooled analysis of two randomised trials.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carb | 2004 |
Cisplatin, vincristine and ifosphamide combination chemotherapy of metastatic seminoma: results of EORTC trial 30874. EORTC GU Group.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Humans; | 1995 |
Carboplatin and ifosfamide and selective consolidation in advanced seminoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modal | 1995 |
[Results of chemotherapy and salvage surgery for advanced testicular cancer].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Mo | 1999 |
24 other studies available for ifosfamide and Seminoma
| Article | Year |
|---|---|
Pure Seminoma and Concurrent Aggressive Lymphoma: Case Report of a Patient With Persistent Müllerian Duct Syndrome.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disorder of Sex Development, 46,XY | 2019 |
A risk-adapted study of cisplatin and etoposide, with or without ifosfamide, in patients with metastatic seminoma: results of the GETUG S99 multicenter prospective study.
Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Surviv | 2014 |
Oncological outcomes of metastatic testicular cancers under centralized management through regional medical network.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disease Man | 2013 |
Conventional Cisplatin-Based Combination Chemotherapy Is Effective in the Treatment of Metastatic Spermatocytic Seminoma with Extensive Rhabdomyosarcomatous Transformation.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Humans; | 2015 |
[Primary mediastinal germs cells tumors: a twenty years experience in a comprehensive cancer center].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cancer Care Facilities; Cisplatin; | 2014 |
Response to anti-programmed cell death protein-1 antibodies in men treated for platinum refractory germ cell cancer relapsed after high-dose chemotherapy and stem cell transplantation.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera | 2017 |
"Burned out" testicular seminoma presenting as a primary gastric malignancy.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; D | 2009 |
Peritoneal relapse of testicular seminomatous germ cell tumor treated successfully with salvage chemotherapy and autologous stem cell transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Humans; Ifosfamide; Male; Middle Aged; Pa | 2011 |
Unusual seminoma revealed by bone metastasis.
Topics: Bone Neoplasms; Cisplatin; Drug Therapy, Combination; Etoposide; Humans; Ifosfamide; Magnetic Resona | 2011 |
Salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) in relapsed or cisplatin-refractory germ cell tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Disease-Free | 2011 |
[Tumour markers--case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Cyclophosph | 2004 |
Metachronous intracranial germinoma in a patient with a previous primary mediastinal seminoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cisplatin; Combin | 2006 |
Clinical study for management of supportive treatment for high-dose chemotherapy with peripheral blood stem cell transplantation (PBSCT) for intractable testicular tumor.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combi | 2006 |
A case of metastatic testicular cancer complicated by tumour lysis syndrome and choriocarcinoma syndrome.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Choriocarcinoma; Cisplatin; Drug A | 2006 |
[Inductive systemic therapy of urological tumors with curative intent].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Cisplatin; Combined Mo | 2007 |
[Clinical analysis of primary mediastinal germ cell tumors].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cisplatin; Comb | 2007 |
[Initial chemotherapy followed by orchiectomy and retroperitoneal lymphadenectomy--a case of seminoma with a testicular tumor and enlarged regional lymph nodes].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Thera | 1994 |
Salvage chemotherapy with vinblastine, ifosfamide, and cisplatin in recurrent seminoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined | 1997 |
[A case of neutropenic enterocolitis in high dose chemotherapy with peripheral blood stem cell transplantation for relapsed testicular tumor].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Enter | 1998 |
High-dose chemotherapy in germ cell tumours: a large single centre experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease-Free Surviva | 1998 |
[Two cases of giant testicular tumor with widespread extension to the spermatic cord: usefulness of upfront chemotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Etoposi | 1999 |
[High dose chemotherapy with autologous stem cell support in the treatment of germ cell tumors: experience of the centre Léon-Bérard between 1982 and 1996].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 1999 |
Positron emission tomography scans in the evaluation of postchemotherapy residual masses in patients with seminoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Humans; Ifosfamide; Male; Me | 1999 |
[Treatment of advanced testicular cancer and toxicity of chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Germinoma; Humans; | 1999 |