Page last updated: 2024-10-29

ifosfamide and Proteinuria

ifosfamide has been researched along with Proteinuria in 22 studies

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Ifosfamide and cisplatin are active agents that are currently used in the treatment of osteosarcoma."7.70Renal function following combination chemotherapy with ifosfamide and cisplatin in patients with osteogenic sarcoma. ( Arndt, C; Hawkins, D; Liedtke, R; Miser, J; Morgenstern, B; Wilson, D, 1999)
" Nephrotoxicity is a known side effect of several treatments, including cisplatin, carboplatin, ifosfamide, radiotherapy and nephrectomy, and can cause glomerular filtration rate (GFR) impairment, proteinuria, tubulopathy, and hypertension."5.01Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer. ( Bökenkamp, A; Kooijmans, EC; Tettero, JM; Tjahjadi, NS; van der Pal, HJ; van Dulmen-den Broeder, E; Veening, MA, 2019)
" Nephrotoxicity is one of these known (acute) side effects of several treatments, including cisplatin, carboplatin, ifosfamide, radiotherapy and nephrectomy, and can cause glomerular filtration rate impairment, proteinuria, tubulopathy and hypertension."4.89Early and late renal adverse effects after potentially nephrotoxic treatment for childhood cancer. ( Blufpand, H; Bökenkamp, A; Jaspers, MW; Knijnenburg, SL; Kremer, LC; Mulder, RL; Schouten-Van Meeteren, AY; van Dulmen-den Broeder, E; Veening, MA, 2013)
"To evaluate proteinuria occurring early after ifosfamide therapy and to assess the use of changes in proteinuria in the prediction of severe chronic nephrotoxicity."3.70Acute changes in urine protein excretion may predict chronic ifosfamide nephrotoxicity: a preliminary observation. ( English, M; Hall, AG; MacLean, FR; Pearson, AD; Skinner, R, 1998)
"Ifosfamide and cisplatin are active agents that are currently used in the treatment of osteosarcoma."3.70Renal function following combination chemotherapy with ifosfamide and cisplatin in patients with osteogenic sarcoma. ( Arndt, C; Hawkins, D; Liedtke, R; Miser, J; Morgenstern, B; Wilson, D, 1999)
"In addition, polyploidy of TEC was observed to correlate with loss of lysozyme staining."1.91Cellular senescence in kidney biopsies is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with karyomegalic interstitial nephropathy. ( Broekhuizen, R; Goldschmeding, R; Haveman, LM; Janssens, GO; Keijzer-Veen, MG; Knoppert, SN; Lilien, MR; Nguyen, TQ; Stokman, MF; Valentijn, FA; van den Berg, G; van den Heuvel-Eibrink, MM; van Kempen, S, 2023)
"The renal Fanconi syndrome is a defect of proximal tubular function causing aminoaciduria and low-molecular-weight proteinuria."1.34Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome. ( Capasso, G; Cutillas, PR; Holmes, E; Maher, AD; Nicholson, JK; Norden, AW; Unwin, RJ; Vilasi, A; Zirah, SF, 2007)
"The patients with prostatic cancer were treated with VIP (vincristine, ifosfamide, peplomycin) chemotherapy and the patients with urothelial cancer were treated with MP (methotrexate, cisplatinum) or MEP (methotrexate, Etoposide, cisplatinum) combination chemotherapy."1.29[Comparative study on urinary parameters reflecting renal damage during chemotherapy for urological cancer]. ( Kitamura, Y; Komatsubara, S; Sakata, Y; Watanabe, M, 1993)
" We observed this acute toxic effect despite the administration of sufficient mesna to prevent hemorrhagic cystitis."1.27Ifosfamide-induced subclinical tubular nephrotoxicity despite mesna. ( Goren, MP; Horowitz, ME; Pratt, CB; Wright, RK, 1987)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's8 (36.36)18.2507
2000's3 (13.64)29.6817
2010's5 (22.73)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Knoppert, SN1
Keijzer-Veen, MG1
Valentijn, FA1
van den Heuvel-Eibrink, MM1
Lilien, MR1
van den Berg, G1
Haveman, LM1
Stokman, MF1
Janssens, GO1
van Kempen, S1
Broekhuizen, R1
Goldschmeding, R1
Nguyen, TQ1
Kooijmans, EC1
Bökenkamp, A2
Tjahjadi, NS1
Tettero, JM1
van Dulmen-den Broeder, E2
van der Pal, HJ1
Veening, MA2
Knijnenburg, SL1
Mulder, RL1
Schouten-Van Meeteren, AY1
Blufpand, H1
Kremer, LC1
Jaspers, MW1
Ramirez, MD1
Mertens, AC1
Esiashvili, N1
Meacham, LR1
Wasilewski-Masker, K1
Yılmaz, S1
Özçakar, ZB1
Taktak, A1
Kiremitçi, S1
Ensari, A1
Dinçaslan, H1
Yalçınkaya, F1
Vello Román, A1
Samprón Rodríguez, M1
Pazos Arias, B1
Romero Reinoso, C1
Peteiro Cancelo, A1
Stöhr, W1
Paulides, M1
Bielack, S1
Jürgens, H1
Treuner, J1
Rossi, R2
Langer, T1
Beck, JD1
Hozhenko, AI1
Trusova, MV1
Vilasi, A1
Cutillas, PR1
Maher, AD1
Zirah, SF1
Capasso, G1
Norden, AW1
Holmes, E1
Nicholson, JK1
Unwin, RJ1
Hacke, M1
Schmoll, HJ1
Alt, JM1
Baumann, K1
Stolte, H1
Kitamura, Y1
Watanabe, M1
Komatsubara, S1
Sakata, Y1
Rossi, RM1
Kist, C1
Wurster, U1
Külpmann, WR1
Ehrich, JH2
Rath, B1
Ullrich, K1
Tokuc, G1
Yalçiner, A1
Kebudi, R1
Dogan, S1
Görgün, O1
Ayan, I1
MacLean, FR1
Skinner, R2
Hall, AG1
English, M1
Pearson, AD2
Arndt, C1
Morgenstern, B1
Hawkins, D1
Wilson, D1
Liedtke, R1
Miser, J1
Gysler, J1
Schunack, W1
Jaehde, U1
Price, L1
Coulthard, MG1
Craft, AW1
Goren, MP3
Pratt, CB3
Meyer, WH1
Wright, RK2
Dodge, RK1
Viar, MJ2
Horowitz, ME1
Patterson, WP1
Khojasteh, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Oral Supplementation With Magnesium to Reduce Febrile Neutropenia in Pediatric Oncology Patients Treated With Cisplatin-Based Chemotherapy: Randomized Clinical Trial[NCT03449693]Phase 2214 participants (Anticipated)Interventional2017-10-19Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ifosfamide and Proteinuria

ArticleYear
Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer.
    The Cochrane database of systematic reviews, 2019, 03-11, Volume: 3

    Topics: Adult; Antineoplastic Agents; Carboplatin; Child; Cisplatin; Glomerular Filtration Rate; Humans; Hyp

2019
Early and late renal adverse effects after potentially nephrotoxic treatment for childhood cancer.
    The Cochrane database of systematic reviews, 2013, Oct-08, Issue:10

    Topics: Adult; Antineoplastic Agents; Carboplatin; Child; Cisplatin; Glomerular Filtration Rate; Humans; Hyp

2013

Trials

2 trials available for ifosfamide and Proteinuria

ArticleYear
Yield of Urinalysis Screening in Pediatric Cancer Survivors.
    Pediatric blood & cancer, 2016, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Databases, Factual; Female; Follow-Up Studies; Glycosuri

2016
[Ifosfamide-induced nephrotoxicity].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1993, Volume: 141, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Cisplatin; Creatinine

1993

Other Studies

18 other studies available for ifosfamide and Proteinuria

ArticleYear
Cellular senescence in kidney biopsies is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with karyomegalic interstitial nephropathy.
    The Journal of pathology, 2023, Volume: 261, Issue:4

    Topics: Biopsy; Cellular Senescence; Child; Humans; Ifosfamide; In Situ Hybridization, Fluorescence; Kidney;

2023
Anti-VEGF-related thrombotic microangiopathy in a child presenting with nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 2016, Volume: 31, Issue:6

    Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Pro

2016
[Nephropathy following administration of angiogenesis inhibitors].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
Ifosfamide-induced nephrotoxicity in 593 sarcoma patients: a report from the Late Effects Surveillance System.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:4

    Topics: Abdomen; Adolescent; Age Factors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth

2007
[Effect of cytostatic ifosfamide on the function of the kidneys in white rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2006, Volume: 52, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Creatinine; Diuresis; Glycosuria; Ifosfamide; Kidney; Ma

2006
Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Chloride Channels; DNA Fingerprinting; Fanconi Syndrome; F

2007
Nephrotoxicity of cis-diamminedichloroplatinum with or without ifosfamide in cancer treatment.
    Clinical physiology and biochemistry, 1983, Volume: 1, Issue:1

    Topics: Albuminuria; alpha-Glucosidases; beta 2-Microglobulin; Cisplatin; Cyclophosphamide; Drug Interaction

1983
[Comparative study on urinary parameters reflecting renal damage during chemotherapy for urological cancer].
    Hinyokika kiyo. Acta urologica Japonica, 1993, Volume: 39, Issue:2

    Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Aminopeptidases; Antineoplastic Combined Chemotherap

1993
Estimation of ifosfamide/cisplatinum-induced renal toxicity by urinary protein analysis.
    Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Cisplatin; Drug Therapy, Combination; Electrophoresis, P

1994
Renal dysfunctions secondary to ifosfamide treatment in children.
    Journal of experimental & clinical cancer research : CR, 1997, Volume: 16, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Dose-Response Relationship,

1997
Acute changes in urine protein excretion may predict chronic ifosfamide nephrotoxicity: a preliminary observation.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:5

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Chronic Disease; Female; Hum

1998
Renal function following combination chemotherapy with ifosfamide and cisplatin in patients with osteogenic sarcoma.
    Medical and pediatric oncology, 1999, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cisplatin;

1999
Monitoring of chemotherapy-induced proteinuria using capillary zone electrophoresis.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Jan-22, Volume: 721, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Buffers; Calibration; Carboplatin; Electropho

1999
Nephrotoxicity after ifosfamide.
    Archives of disease in childhood, 1990, Volume: 65, Issue:7

    Topics: Adolescent; Albuminuria; Bone and Bones; Child; Child, Preschool; Cross-Sectional Studies; Female; G

1990
Mesna excretion and ifosfamide nephrotoxicity in children.
    Cancer research, 1989, Dec-15, Volume: 49, Issue:24 Pt 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Creatinine; Female; Humans; Ifosfamide; Kidney Diseases;

1989
Tubular nephrotoxicity during long-term ifosfamide and mesna therapy.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:1

    Topics: Acetylglucosaminidase; Aminopeptidases; Antineoplastic Combined Chemotherapy Protocols; Biomarkers;

1989
Ifosfamide-induced subclinical tubular nephrotoxicity despite mesna.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Acetylglucosaminidase; Adolescent; Adult; Aminopeptidases; CD13 Antigens; Child; Child, Preschool; C

1987
Ifosfamide-induced renal tubular defects.
    Cancer, 1989, Feb-15, Volume: 63, Issue:4

    Topics: Hematuria; Humans; Hydrogen-Ion Concentration; Ifosfamide; Kidney Diseases; Kidney Tubules; Lymphoma

1989