Page last updated: 2024-10-29

ifosfamide and Peritoneal Carcinomatosis

ifosfamide has been researched along with Peritoneal Carcinomatosis in 31 studies

Research Excerpts

ExcerptRelevanceReference
"This study investigated the feasibility and efficacy of doxorubicin dose-escalated chemotherapy in combination with ifosfamide in patients with malignant mesothelioma."9.07A phase II trial of dose-escalated doxorubicin and ifosfamide/mesna in patients with malignant mesothelioma. ( Corthouts, B; Dirix, LY; Prové, A; Schrijvers, D; van Marck, E; van Meerbeeck, J; van Oosterom, AT; Vermeire, P, 1994)
"Twenty-six patients with unresectable diffuse malignant mesothelioma were enrolled in Southwest Oncology Group (SWOG) study 8731 and treated with ifosfamide, 2 g/m2 intravenously for 4 days, and mesna 2 g/m2 intravenously for 5 days, every 3 weeks."9.07A phase II evaluation of ifosfamide and mesna in unresectable diffuse malignant mesothelioma. A Southwest Oncology Group study. ( Balcerzak, SP; Berenberg, JL; Keppen, MD; Metch, B; Militello, L; Pierce, HI; Zidar, BL, 1992)
"Forty three patients with histologically confirmed malignant mesothelioma were entered onto an Eastern Cooperative Oncology Group phase II study of ifosfamide given with mesna."9.07An extended phase II trial of ifosfamide plus mesna in malignant mesothelioma. ( Borden, EC; Falkson, CI; Falkson, G; Hayes, JA; Hunt, M; Smith, TJ, 1992)
"We report a case of retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide."7.70[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide]. ( Fujinami, K; Kondoh, I; Kondoh, K; Kushida, K; Miura, T, 1999)
"Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature."5.33A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide. ( Chuman, H; Ishiguro, S; Moriya, Y; Yamamoto, S, 2006)
"This study investigated the feasibility and efficacy of doxorubicin dose-escalated chemotherapy in combination with ifosfamide in patients with malignant mesothelioma."5.07A phase II trial of dose-escalated doxorubicin and ifosfamide/mesna in patients with malignant mesothelioma. ( Corthouts, B; Dirix, LY; Prové, A; Schrijvers, D; van Marck, E; van Meerbeeck, J; van Oosterom, AT; Vermeire, P, 1994)
"Twenty-six patients with unresectable diffuse malignant mesothelioma were enrolled in Southwest Oncology Group (SWOG) study 8731 and treated with ifosfamide, 2 g/m2 intravenously for 4 days, and mesna 2 g/m2 intravenously for 5 days, every 3 weeks."5.07A phase II evaluation of ifosfamide and mesna in unresectable diffuse malignant mesothelioma. A Southwest Oncology Group study. ( Balcerzak, SP; Berenberg, JL; Keppen, MD; Metch, B; Militello, L; Pierce, HI; Zidar, BL, 1992)
"Forty three patients with histologically confirmed malignant mesothelioma were entered onto an Eastern Cooperative Oncology Group phase II study of ifosfamide given with mesna."5.07An extended phase II trial of ifosfamide plus mesna in malignant mesothelioma. ( Borden, EC; Falkson, CI; Falkson, G; Hayes, JA; Hunt, M; Smith, TJ, 1992)
"We present a patient with peritoneal carcinosarcoma who was treated with the alkylating agent ifosfamide and experienced a rapid decline in mental status."4.90Ifosfamide chemotherapy and nonconvulsive status epilepticus: case report and review of the literature. ( Friedman, D; Racela, R; Taupin, D, 2014)
"We report a case of postoperative recurrence of liposarcoma of the mesenterium successfully treated by chemotherapy using ifosfamide (IFM) and cisplatin (CDDP)."3.73[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy]. ( Aoki, T; Kondo, M; Mizumura, Y; Moritani, M; Sasaki, Y; Tsuchida, A; Wada, T; Yamamoto, K, 2006)
"We report a case of retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide."3.70[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide]. ( Fujinami, K; Kondoh, I; Kondoh, K; Kushida, K; Miura, T, 1999)
"Ifosfamide has been shown to possess modest activity in patients with platinum/cyclophosphamide refractory ovarian cancer."2.69Phase 2 trial of single agent ifosfamide/mesna in patients with platinum/paclitaxel refractory ovarian cancer who have not previously been treated with an alkylating agent. ( Belinson, J; Hurteau, J; Kennedy, A; Kulp, B; Markman, M; Peterson, G; Sutton, G; Webster, K, 1998)
"Intraperitoneal carcinomatosis (PC) may occur with several tumor entities."2.49Extravascular use of drug-eluting beads: a promising approach in compartment-based tumor therapy. ( Binder, S; Keese, M; Lewis, AL; Löhr, JM, 2013)
"treatment with ifosfamide alone or ifosfamide combined with microencapsulated CYP2B1 expressing cells."1.34Targeted intraabdominal chemotherapy for peritoneal carcinomatosis. ( Löhr, M; Samel, S, 2007)
"treatment with ifosfamide alone or ifosfamide combined with microencapsulated CYP2B1-expressing cells."1.33Peritoneal cancer treatment with CYP2B1 transfected, microencapsulated cells and ifosfamide. ( Hafner, M; Jesnowski, R; Keese, M; Löhr, M; Lux, A; Post, S; Prosst, R; Saller, R; Samel, S; Sturm, J, 2006)
"Angiosarcomas are rare soft tissue malignancies."1.33Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature. ( Bearz, A; Berretta, M; Berretta, S; Brollo, A; Buonadonna, A; Canzonieri, V; Frustaci, S; Morra, A; Rupolo, M; Tirelli, U, 2006)
"Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature."1.33A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide. ( Chuman, H; Ishiguro, S; Moriya, Y; Yamamoto, S, 2006)
" As cytostatics for hyperthermic peritoneal perfusion, we have used Mitomycin in a dosage of 18 mg/m2 plus Melphalan in a dosage of 25 mg/m2."1.32Cytoreductive surgery plus intraperitoneal hyperthermic perfusion is an effective treatment for metastasized malignant mixed mesodermal tumours (MMMT)--report of six cases. ( Müller, H; Nakchbandi, V, 2004)
"The authors report a case of encephalopathy after treatment with ifosfamide treated by a methylene blue infusion."1.29[Treatment of ifosfamide induced encephalopathy with methylene-blue]. ( Dreyfus, G; Eftekari, P; Ferrero, JM; Largillier, R; Namer, M, 1995)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's10 (32.26)18.2507
2000's11 (35.48)29.6817
2010's7 (22.58)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Sjoberg Bexelius, T1
Chisholm, JC1
Okoye, B1
Cecil, T1
Angelini, P1
Dayal, S1
Taupin, D1
Racela, R1
Friedman, D1
Binder, S1
Lewis, AL1
Löhr, JM1
Keese, M2
Lee, M1
Kim, SW1
Nam, EJ1
Cho, H1
Kim, JH1
Kim, YT1
Kim, S1
Fizazi, K1
Pagliaro, L1
Laplanche, A1
Fléchon, A1
Mardiak, J1
Geoffrois, L1
Kerbrat, P1
Chevreau, C1
Delva, R1
Rolland, F1
Theodore, C1
Roubaud, G1
Gravis, G1
Eymard, JC1
Malhaire, JP1
Linassier, C1
Habibian, M1
Martin, AL1
Journeau, F1
Reckova, M1
Logothetis, C1
Culine, S1
Jaśkowski, P1
Krzanowska, K1
Miarka, P1
Krzanowski, M1
Sułowicz, W1
Honoré, C1
Atallah, V1
Mir, O1
Orbach, D1
Ferron, G1
LePéchoux, C1
Delhorme, JB1
Philippe-Chomette, P1
Sarnacki, S1
Msika, S1
Terrier, P1
Glehen, O1
Martelli, H1
Minard-Colin, V1
Bertucci, F1
Blay, JY1
Bonvalot, S1
Elias, D1
LeCesne, A1
Sargos, P1
Sneag, DB1
Ramaiya, N1
O'Regan, KN1
Jagannathan, JP1
Hornick, JL1
Ho, VT1
Hayes, JH1
Boisselier, P1
Foucher, F1
Boucher, E1
Raoul, JL1
Suhr, M1
Gottschalk, J1
Kreusch, T1
Müller, H1
Nakchbandi, V1
Hemmings, C1
Fisher, C1
de Bree, E1
Romanos, J1
Relakis, K1
Tsiftsis, DD1
Dusenbery, KE1
Potish, RA1
Argenta, PA1
Judson, PL1
Samel, S2
Lux, A1
Jesnowski, R1
Prosst, R1
Saller, R1
Hafner, M1
Sturm, J1
Post, S1
Löhr, M2
Sasaki, Y1
Moritani, M1
Wada, T1
Mizumura, Y1
Kondo, M1
Yamamoto, K1
Tsuchida, A1
Aoki, T1
Berretta, M1
Rupolo, M1
Buonadonna, A1
Canzonieri, V1
Brollo, A1
Morra, A1
Berretta, S1
Bearz, A1
Tirelli, U1
Frustaci, S1
Ishiguro, S1
Yamamoto, S1
Chuman, H1
Moriya, Y1
Miyahara, K1
Ferrero, JM1
Eftekari, P1
Largillier, R1
Dreyfus, G1
Namer, M1
de Jonge, MJ1
van Dam, PA1
Van Marck, E2
Prove, A2
van Oosterom, AT2
Dirix, LY1
van Meerbeeck, J1
Schrijvers, D1
Corthouts, B1
Vermeire, P1
Raspagliesi, F1
Quattrone, P1
Grosso, G1
Cobellis, L1
Di Re, E1
Markman, M1
Kennedy, A1
Sutton, G1
Hurteau, J1
Webster, K1
Peterson, G1
Kulp, B1
Belinson, J1
Fujinami, K1
Kondoh, K1
Kondoh, I1
Miura, T1
Kushida, K1
Zidar, BL1
Metch, B1
Balcerzak, SP1
Pierce, HI1
Militello, L1
Keppen, MD1
Berenberg, JL1
Falkson, G1
Hunt, M1
Borden, EC1
Hayes, JA1
Falkson, CI1
Smith, TJ1
Chauffert, B1
Dimanche-Boitrel, MT1
Genne, P1
Petit, JM1
Onier, N1
Jeannin, JF1
Pratt, CB1
Meyer, WH1
Jenkins, JJ1
Avery, L1
McKay, CP1
Wyatt, RJ1
Hancock, ML1
Nishida, T1
Obuchi, T1
Sasaki, T1
Nagasue, N1
Yakushiji, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intra-tumor Injection of Drug-eluting Microspheres Loading With Chemodrug Plus Checkpoint Inhibitors and IL2 for Treatment of Advanced Solid Tumors[NCT04770207]Phase 2100 participants (Anticipated)Interventional2020-11-01Recruiting
A Risk-Adapted Strategy of the Use of Dose-Dense Chemotherapy in Patients With Poor-Prognosis Disseminated Non-Seminomatous Germ Cell Tumors[NCT00104676]Phase 3263 participants (Actual)Interventional2003-11-26Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival

To evaluated the overall survival in both groups in participants presenting fast and slow decrease in serum levels of tumor markers. The median overall survival was defined as the median percentage of participants alive after 1 course of treatment. (NCT00104676)
Timeframe: 3 years from randomization

Interventionpercentage of participants (Number)
Arm I65
Arm II73

Progression-free Survival Rate After 1 Course of Treatment

Primary objective is to compare the progression-free survival of participants after 1 cycle of treatment, treated randomly by 3 additional cycles of BEP (Arm I) or by T-BEP-Oxaliplatin/cisplatin-ifosfamide-Bleomycin (Arm II). The median progression-free survival rate was defined as the median percentage of participants alive without disease progression after 1 course of treatment. (NCT00104676)
Timeframe: 3 years from randomization

Interventionpercentage of participants (Number)
Arm I48
Arm II59

Reviews

3 reviews available for ifosfamide and Peritoneal Carcinomatosis

ArticleYear
Ifosfamide chemotherapy and nonconvulsive status epilepticus: case report and review of the literature.
    Clinical EEG and neuroscience, 2014, Volume: 45, Issue:3

    Topics: Carcinosarcoma; Cerebral Cortex; Diagnosis, Differential; Electroencephalography; Epilepsy, Generali

2014
Extravascular use of drug-eluting beads: a promising approach in compartment-based tumor therapy.
    World journal of gastroenterology, 2013, Nov-21, Volume: 19, Issue:43

    Topics: Animals; Antineoplastic Agents; Carcinoma; Cell- and Tissue-Based Therapy; Chemoembolization, Therap

2013
On the apparent failure of adjuvant pelvic radiotherapy to improve survival for women with uterine sarcomas confined to the uterus.
    American journal of clinical oncology, 2005, Volume: 28, Issue:3

    Topics: Abdominal Neoplasms; Antineoplastic Agents; Brachytherapy; Chemotherapy, Adjuvant; Combined Modality

2005

Trials

5 trials available for ifosfamide and Peritoneal Carcinomatosis

ArticleYear
Personalised chemotherapy based on tumour marker decline in poor prognosis germ-cell tumours (GETUG 13): a phase 3, multicentre, randomised trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:13

    Topics: Adolescent; Adult; Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomark

2014
A phase II trial of dose-escalated doxorubicin and ifosfamide/mesna in patients with malignant mesothelioma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Feasibility Studies; Femal

1994
Phase 2 trial of single agent ifosfamide/mesna in patients with platinum/paclitaxel refractory ovarian cancer who have not previously been treated with an alkylating agent.
    Gynecologic oncology, 1998, Volume: 70, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carboplatin; Cisplatin; Cysta

1998
A phase II evaluation of ifosfamide and mesna in unresectable diffuse malignant mesothelioma. A Southwest Oncology Group study.
    Cancer, 1992, Nov-15, Volume: 70, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Ifosfamide; Male; Mesna

1992
An extended phase II trial of ifosfamide plus mesna in malignant mesothelioma.
    Investigational new drugs, 1992, Volume: 10, Issue:4

    Topics: Drug Administration Schedule; Female; Humans; Ifosfamide; Infusions, Intravenous; Kidney Diseases; M

1992

Other Studies

23 other studies available for ifosfamide and Peritoneal Carcinomatosis

ArticleYear
Hyperthermic intraperitoneal chemotherapy (HIPEC) as another treatment modality for desmoplastic round cell tumour patients: first paediatric experience from UK.
    BMJ case reports, 2021, Jan-28, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cisplatin; Cyclophosph

2021
ATP-based chemotherapy response assay in primary or recurrent ovarian and peritoneal cancer.
    Yonsei medical journal, 2014, Volume: 55, Issue:6

    Topics: Adenocarcinoma, Clear Cell; Adenosine Triphosphate; Adult; Aged; Antineoplastic Combined Chemotherap

2014
[Patient receiving peritoneal dialysis after treatment of ovarian cancer].
    Przeglad lekarski, 2014, Volume: 71, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Humans; If

2014
Abdominal desmoplastic small round cell tumor without extraperitoneal metastases: Is there a benefit for HIPEC after macroscopically complete cytoreductive surgery?
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined

2017
Peritoneal relapse of testicular seminomatous germ cell tumor treated successfully with salvage chemotherapy and autologous stem cell transplantation.
    Clinical genitourinary cancer, 2011, Volume: 9, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Humans; Ifosfamide; Male; Middle Aged; Pa

2011
[Medical treatment of a voluminous tumor of the mesenteric root].
    Gastroenterologie clinique et biologique, 2003, Volume: 27, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fibromatosis, Aggressive; Human

2003
Metastatic malignant solitary fibrous tumour to the infra-temporal fossa.
    International journal of oral and maxillofacial surgery, 2003, Volume: 32, Issue:6

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Humans; Ifosfam

2003
Cytoreductive surgery plus intraperitoneal hyperthermic perfusion is an effective treatment for metastasized malignant mixed mesodermal tumours (MMMT)--report of six cases.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2004, Volume: 30, Issue:5

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined

2004
Primary omental synovial sarcoma: a case with cytogenetic confirmation.
    Pathology, 2004, Volume: 36, Issue:2

    Topics: Adult; Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; D

2004
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant mixed mesodermal tumours with peritoneal dissemination.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy

2005
Peritoneal cancer treatment with CYP2B1 transfected, microencapsulated cells and ifosfamide.
    Cancer gene therapy, 2006, Jan-01, Volume: 13, Issue:1

    Topics: Animals; Cytochrome P-450 CYP2B1; Drug Compounding; Genetic Therapy; Ifosfamide; Male; Mice; Mice, I

2006
[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colon, Sigmoid; Drug Administration Sched

2006
Metastatic angiosarcoma of the kidney: a case report with treatment approach and review of the literature.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:2

    Topics: Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fat

2006
A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide.
    Japanese journal of clinical oncology, 2006, Volume: 36, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Administration S

2006
Targeted intraabdominal chemotherapy for peritoneal carcinomatosis.
    Cancer treatment and research, 2007, Volume: 134

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents, Alkylating; Carcinoma; Cell Line, Tumor; Ce

2007
[Chemotherapy of a human pseudomyxoma peritonei transplanted in the nude mouse].
    Nihon Gan Chiryo Gakkai shi, 1984, Jul-20, Volume: 19, Issue:6

    Topics: Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cystadenoma; Doxoru

1984
[Treatment of ifosfamide induced encephalopathy with methylene-blue].
    Bulletin du cancer, 1995, Volume: 82, Issue:7

    Topics: Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Female; Humans; Ifosfamide; Methylene Blue;

1995
Primary extrauterine müllerian adenosarcoma of the peritoneum.
    Gynecologic oncology, 1995, Volume: 57, Issue:1

    Topics: Adenosarcoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Do

1995
Malignant degeneration in leiomyomatosis peritonealis disseminata.
    Gynecologic oncology, 1996, Volume: 61, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Dacarbazine;

1996
[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

1999
[Experimental chemotherapy of peritoneal carcinomatosis of colonic origin in rats].
    Gastroenterologie clinique et biologique, 1992, Volume: 16, Issue:3

    Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Cyclophosphamide; Disease Models, Anim

1992
Ifosfamide, Fanconi's syndrome, and rickets.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Chronic Kidney Disease-Mineral an

1991
Extragenital malignant mixed Müllerian tumor: a case report.
    The Kurume medical journal, 1988, Volume: 35, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Humans; I

1988