Page last updated: 2024-10-29

ifosfamide and Neuroblastoma

ifosfamide has been researched along with Neuroblastoma in 41 studies

Neuroblastoma: A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Research Excerpts

ExcerptRelevanceReference
"One hundred seventy-three eligible patients more than 1 year of age with disseminated neuroblastoma received two courses of one of the following: ifosfamide (IFOS) 2 g/m2/d for 4 days intravenously (IV) plus mesna; carboplatin (CARB) 560 mg/m2 i."9.07Phase II investigational window using carboplatin, iproplatin, ifosfamide, and epirubicin in children with untreated disseminated neuroblastoma: a Pediatric Oncology Group study. ( Berkow, RL; Buchanan, GR; Cantor, AB; Castleberry, RP; Green, AA; Hayes, FA; Joshi, V; Leventhal, B; Mahoney, DH; Smith, EI, 1994)
"Three patients with stage 4 neuroblastoma were treated with a schedule comprising alternating modules of myelosuppressive (ifosfamide, etoposide, doxorubicin) and less myelosuppressive (vincristine, cisplatin) drugs given every 10 days regardless of the neutrophil count."9.07Prohibitive toxicity of a dose-intense regime for metastatic neuroblastoma containing ifosfamide, doxorubicin and cisplatin. ( Craft, AW; Lowis, SP; Pearson, AD; Reid, MM, 1993)
"Twenty-five patients with progressive or recurrent neuroblastoma were treated with single-agent ifosfamide."9.06Single-agent ifosfamide in patients with recurrent neuroblastoma (ENSG study 2). European Neuroblastoma Study Group. ( de Kraker, J; Hartmann, O; Ninane, J; Pritchard, J, 1987)
"The authors report a retrospective analysis of high-dose ifosfamide, carboplatin, and etoposide (HD-ICE) for patients with refractory or relapsed neuroblastoma (NB)."8.89Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature. ( Basu, EM; Cheung, NK; Kramer, K; Kushner, BH; Modak, S; Roberts, SS, 2013)
"Patients older than 1 year with either metastatic or localised stage 2-3 MYCN-amplified neuroblastoma received 2 courses of high-dose topotecan (HD-TPT) 6mg/m(2) and high-dose cyclophosphamide (HD-CPM) 140 mg/kg, followed by 2 courses of ifosfamide, carboplatin and etoposide (ICE) every 28 days."7.77Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma. ( Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L, 2011)
"Recurrent and refractory neuroblastoma responds well to chemotherapy regimen of ifosphamide plus carboplatin."7.73[Efficacy of chemotherapy regimen using ifosphamide and carboplatin on recurrent or refractory neuroblastoma]. ( Ling, JY; Sun, XF; Wang, ZH; Xia, Y; Zhen, ZJ, 2006)
"A prospective study of the effectiveness of ifosfamide as a single agent in the management of previously untreated patients with Evans stage IV neuroblastoma was undertaken."7.67Ifosfamide in previously untreated disseminated neuroblastoma. Results of Study 3A of the European Neuroblastoma Study Group. ( Bowman, A; De Kraker, J; Kellie, SJ; Lilleyman, JS; Pritchard, J, 1988)
"The esthesioneuroblastoma is a rare neuroendocrine tumor that derives from the olfactory cells."5.36Advanced adult esthesioneuroblastoma successfully treated with cisplatin and etoposide alternated with doxorubicin, ifosfamide and vincristine. ( Biamonte, R; Ceniti, S; Conforti, S; De Simone, R; Filice, A; Liguori, V; Manfredi, C; Mastroianni, C; Palazzo, S; Patitucci, G; Rovito, A; Turano, S; Viscomi, C, 2010)
"Childhood neuroblastoma is a neural crest-derived tumor that presents most commonly during this period of life."5.28Combination chemotherapy with ifosfamide and etoposide is effective in the treatment of central nervous system metastasis of childhood neuroblastoma. ( Watts, RG, 1992)
"Twenty-nine patients diagnosed with recurrent neuroblastoma or PNET were treated with a combination chemotherapy regimen of cisplatin, 160 mg/m(2)/96 hours; doxorubicin, 40 mg/m(2)/96 hours; and escalated doses of etoposide and ifosfamide."5.09A phase I dose escalation of combination chemotherapy with granulocyte-macrophage-colony stimulating factor in patients with neuroblastoma. ( Fernandez, MC; Gerbing, RR; Krailo, MD; Matthay, KK, 2000)
"One hundred seventy-three eligible patients more than 1 year of age with disseminated neuroblastoma received two courses of one of the following: ifosfamide (IFOS) 2 g/m2/d for 4 days intravenously (IV) plus mesna; carboplatin (CARB) 560 mg/m2 i."5.07Phase II investigational window using carboplatin, iproplatin, ifosfamide, and epirubicin in children with untreated disseminated neuroblastoma: a Pediatric Oncology Group study. ( Berkow, RL; Buchanan, GR; Cantor, AB; Castleberry, RP; Green, AA; Hayes, FA; Joshi, V; Leventhal, B; Mahoney, DH; Smith, EI, 1994)
"Three patients with stage 4 neuroblastoma were treated with a schedule comprising alternating modules of myelosuppressive (ifosfamide, etoposide, doxorubicin) and less myelosuppressive (vincristine, cisplatin) drugs given every 10 days regardless of the neutrophil count."5.07Prohibitive toxicity of a dose-intense regime for metastatic neuroblastoma containing ifosfamide, doxorubicin and cisplatin. ( Craft, AW; Lowis, SP; Pearson, AD; Reid, MM, 1993)
"Twenty-five patients with progressive or recurrent neuroblastoma were treated with single-agent ifosfamide."5.06Single-agent ifosfamide in patients with recurrent neuroblastoma (ENSG study 2). European Neuroblastoma Study Group. ( de Kraker, J; Hartmann, O; Ninane, J; Pritchard, J, 1987)
"The authors report a retrospective analysis of high-dose ifosfamide, carboplatin, and etoposide (HD-ICE) for patients with refractory or relapsed neuroblastoma (NB)."4.89Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature. ( Basu, EM; Cheung, NK; Kramer, K; Kushner, BH; Modak, S; Roberts, SS, 2013)
"Phase II studies conducted in Europe and the USA on pediatric solid tumors have shown that ifosfamide, as a single agent, is an active drug against a variety of neoplasms - rhabdomyosarcoma (RMS), some non-RMS soft tissue sarcomas, Wilms' tumor, bone sarcomas and neuroblastoma."4.82Ifosfamide in pediatric solid tumors. ( Bisogno, G; Carli, M; Passone, E; Perilongo, G, 2003)
"Patients older than 1 year with either metastatic or localised stage 2-3 MYCN-amplified neuroblastoma received 2 courses of high-dose topotecan (HD-TPT) 6mg/m(2) and high-dose cyclophosphamide (HD-CPM) 140 mg/kg, followed by 2 courses of ifosfamide, carboplatin and etoposide (ICE) every 28 days."3.77Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma. ( Castellano, A; De Ioris, MA; De Pasquale, MD; De Vito, R; Donfrancesco, A; Garganese, MC; Ilari, I; Inserra, A; Jenkner, A; Locatelli, F; Natali, G; Ravà, L, 2011)
"Recurrent and refractory neuroblastoma responds well to chemotherapy regimen of ifosphamide plus carboplatin."3.73[Efficacy of chemotherapy regimen using ifosphamide and carboplatin on recurrent or refractory neuroblastoma]. ( Ling, JY; Sun, XF; Wang, ZH; Xia, Y; Zhen, ZJ, 2006)
"Neuroblastomas, nephroblastomas, malignant mesenchymal tumors, including rhabdomyosarcomas, Ewing's sarcomas, osteosarcomas, brain tumors, and non-Hodgkin's lymphomas respond to ifosfamide monotherapy."3.69Ifosfamide in the treatment of pediatric malignancies. ( Behrendt, H; de Kraker, J; Michiels, E; van den Berg, H; Voûte, PA, 1996)
"We studied two children with recurrent cancer, who during treatment with ifosfamide developed severe encephalopathy characterized by coma of several days duration."3.67Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors. ( Barak, LS; Estrada, J; Gieron, MA, 1988)
"A prospective study of the effectiveness of ifosfamide as a single agent in the management of previously untreated patients with Evans stage IV neuroblastoma was undertaken."3.67Ifosfamide in previously untreated disseminated neuroblastoma. Results of Study 3A of the European Neuroblastoma Study Group. ( Bowman, A; De Kraker, J; Kellie, SJ; Lilleyman, JS; Pritchard, J, 1988)
"Neuroblastoma is the most common extracranial and deadly solid tumor in children."2.76Did salvage ICE chemotherapy improve the outcome in primary resistant/relapsing stage III/IV neuroblastoma? ( Abdel Rahman, H; El Debawy, E; Ezzat, S; Mostafa, NE; Moussa, EA; Rayan, Ael R; Yones, A; Zekri, WZ, 2011)
"(4) Characteristics of second neoplasms: Among the seven children with second neoplasms, five children had leukemia, 3 patients with rhabdomyosarcoma were combined with radiotherapy."1.72A report on second neo-plasms in seven children with solid tumors. ( Hu, H; Huang, D; Li, F; Li, J; Li, R; Liu, Z; Zhang, W, 2022)
"Adult neuroblastoma is an extremely infrequent neoplasm, usually occurring in the adrenal medulla or in the paraspinal sympathetic ganglia, as its childhood counterpart."1.51Extra-Adrenal Adult Neuroblastoma With Aberrant Germ Cell Marker Expression: Maturation After Chemotherapy as an Important Clue to a Challenging Diagnosis. ( Berbegall, AP; Blanquer-Maceíras, MT; Ferrández, A; Machado, I; Martinez-Ciarpaglini, C; Navarro, S; Nieto, G; Noguera, R; Yoshida, A, 2019)
"Methylene blue and thiamine have been occasionally successful as treatment."1.43The Use of Continuous Veno-Venous Hemodiafiltration in the Management of Ifosfamide-induced Encephalopathy: A Case Report. ( HaDuong, JH; Yeo, KK, 2016)
"Patients with infratentorial brain metastases of highly malignant pediatric non-epithelial tumors are in a severe clinical state, but still can have longer and useful lives with aggressive multimodal treatments combined with radical surgical resection."1.37Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports. ( Kumabe, T; Niizuma, H; Osawa, S; Saito, R; Sonoda, Y; Tominaga, T; Watanabe, M, 2011)
"The esthesioneuroblastoma is a rare neuroendocrine tumor that derives from the olfactory cells."1.36Advanced adult esthesioneuroblastoma successfully treated with cisplatin and etoposide alternated with doxorubicin, ifosfamide and vincristine. ( Biamonte, R; Ceniti, S; Conforti, S; De Simone, R; Filice, A; Liguori, V; Manfredi, C; Mastroianni, C; Palazzo, S; Patitucci, G; Rovito, A; Turano, S; Viscomi, C, 2010)
"Neuroblastoma is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life."1.36Neuroblastoma in an adult: case report. ( Ferreti Bonan, PR; Martelli-Júnior, H; Miranda Soares, PB; Pereira DE Souza, W; Quirino Filho, S, 2010)
"Childhood neuroblastoma is a neural crest-derived tumor that presents most commonly during this period of life."1.28Combination chemotherapy with ifosfamide and etoposide is effective in the treatment of central nervous system metastasis of childhood neuroblastoma. ( Watts, RG, 1992)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19905 (12.20)18.7374
1990's12 (29.27)18.2507
2000's12 (29.27)29.6817
2010's11 (26.83)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Hu, H1
Zhang, W1
Li, J1
Li, F1
Li, R1
Liu, Z1
Huang, D1
Martinez-Ciarpaglini, C1
Machado, I1
Yoshida, A1
Nieto, G1
Berbegall, AP1
Blanquer-Maceíras, MT1
Noguera, R1
Ferrández, A1
Navarro, S1
Yeo, KK1
HaDuong, JH1
Zage, PE1
Kletzel, M1
Murray, K1
Marcus, R1
Castleberry, R2
Zhang, Y2
London, WB2
Kretschmar, C1
Mullah-Ali, A1
Ramsay, JA1
Bourgeois, JM1
Hodson, I1
Macdonald, P1
Midia, M1
Portwine, C1
Gutweiler, JR1
Yu, DC1
Kim, HB1
Kozakewich, HP1
Marcus, KJ1
Shamberger, RC1
Weldon, CB1
Turano, S1
Mastroianni, C1
Manfredi, C1
Biamonte, R1
Ceniti, S1
Liguori, V1
De Simone, R1
Conforti, S1
Filice, A1
Rovito, A1
Viscomi, C1
Patitucci, G1
Palazzo, S1
De Ioris, MA1
Castellano, A2
Ilari, I2
Garganese, MC1
Natali, G1
Inserra, A2
De Vito, R1
Ravà, L1
De Pasquale, MD1
Locatelli, F1
Donfrancesco, A2
Jenkner, A2
Osawa, S1
Kumabe, T1
Saito, R1
Sonoda, Y1
Niizuma, H1
Watanabe, M1
Tominaga, T1
Miranda Soares, PB1
Quirino Filho, S1
Pereira DE Souza, W1
Ferreti Bonan, PR1
Martelli-Júnior, H1
Chen, N1
Hanly, L1
Rieder, M1
Yeger, H1
Koren, G1
Zhang, WL1
Huang, DS1
Yang, YP1
Liu, XC1
Wu, YP1
Sugito, K1
Furuya, T1
Kaneda, H1
Masuko, T1
Ohashi, K1
Inoue, M1
Ikeda, T1
Koshinaga, T1
Yagasaki, H1
Mugishima, H1
Maebayashi, T1
Abdel Rahman, H1
Moussa, EA1
Zekri, WZ1
El Debawy, E1
Mostafa, NE1
Yones, A1
Ezzat, S1
Rayan, Ael R1
Kushner, BH2
Modak, S1
Kramer, K1
Basu, EM1
Roberts, SS1
Cheung, NK2
Carli, M1
Passone, E1
Perilongo, G1
Bisogno, G1
Milano, GM1
De Sio, L1
Cozza, R1
Fidani, P1
Deb, G1
De Laurentis, C1
Dominici, C1
Yamada, K1
Sugiura, H1
Suzuki, Y1
Takahashi, M1
Bagatell, R1
Rumcheva, P1
Cohn, SL1
Look, AT1
Brodeur, GM1
Frantz, C1
Joshi, V2
Thorner, P1
Rao, PV1
Bowman, LC1
Zhen, ZJ1
Sun, XF1
Xia, Y1
Wang, ZH1
Ling, JY1
Cairo, MS1
Kamen, BA1
Frenkel, E1
Colvin, OM1
Castleberry, RP1
Cantor, AB1
Green, AA1
Berkow, RL1
Buchanan, GR1
Leventhal, B1
Mahoney, DH1
Smith, EI1
Hayes, FA1
Lowis, SP1
Pearson, AD2
Reid, MM1
Craft, AW1
Matsumoto, K2
Miyajima, Y2
Numata, S1
Mori, H1
Fukuda, M2
Horibe, K2
Voûte, PA1
van den Berg, H1
Behrendt, H1
Michiels, E1
de Kraker, J4
Kirch, C1
Gachot, B1
Germann, N1
Blot, F1
Nitenberg, G1
Fernandez, MC1
Krailo, MD1
Gerbing, RR1
Matthay, KK1
Fulda, S1
Fichtner, I1
Hero, B2
Berthold, F2
Kondo, M1
Inaba, J1
Miyashita, Y1
Hunneman, DH1
Gahr, M1
Pratt, CB1
Watts, RG1
Iwasaku-Fujimoto, M1
Fujiwara, F1
Todo, S1
Morioka, Y1
Imashuku, S1
Pinkerton, CR1
Zucker, JM1
Hartmann, O2
Pritchard, J4
Broadbent, V1
Morris-Jones, P1
Breatnach, F1
Craft, AE1
Wallendszus, KR1
Gieron, MA1
Barak, LS1
Estrada, J1
Ninane, J1
Kellie, SJ2
Lilleyman, JS2
Bowman, A2
Muchi, H1
Taniguchi, Y1
Makino, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PHASE III MULTICENTRE TRIAL OF TREATMENT OF NEUROBLASTOMA IN CHILDREN AND ADOLESCENTS[NCT00002802]Phase 3500 participants (Anticipated)Interventional1990-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for ifosfamide and Neuroblastoma

ArticleYear
Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 18; Chromosomes, Human, X;

2008
Ifosfamide, carboplatin, and etoposide for neuroblastoma: a high-dose salvage regimen and review of the literature.
    Cancer, 2013, Feb-01, Volume: 119, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carboplati

2013
Ifosfamide in pediatric solid tumors.
    Oncology, 2003, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Cyclophosphamide; Germinoma; Humans; Ifosf

2003
The use of ifosfamide, carboplatin, and etoposide in children with solid tumors.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Etoposide; Humans; Ifosfamide; L

1995
Current studies of ifosfamide for pediatric solid tumors and leukemia in the United States.
    Seminars in oncology, 1992, Volume: 19, Issue:6 Suppl 12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Chil

1992

Trials

9 trials available for ifosfamide and Neuroblastoma

ArticleYear
Did salvage ICE chemotherapy improve the outcome in primary resistant/relapsing stage III/IV neuroblastoma?
    Journal of the Egyptian National Cancer Institute, 2011, Volume: 23, Issue:1

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Pres

2011
Ifosfamide/carboplatin/etoposide (ICE) as front-line, topotecan/cyclophosphamide as second-line and oral temozolomide as third-line treatment for advanced neuroblastoma over one year of age.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 2004, Volume: 93, Issue:445

    Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols

2004
Outcomes of children with intermediate-risk neuroblastoma after treatment stratified by MYCN status and tumor cell ploidy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Proto

2005
Phase II investigational window using carboplatin, iproplatin, ifosfamide, and epirubicin in children with untreated disseminated neuroblastoma: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Presch

1994
Prohibitive toxicity of a dose-intense regime for metastatic neuroblastoma containing ifosfamide, doxorubicin and cisplatin.
    Cancer chemotherapy and pharmacology, 1993, Volume: 31, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Diseases; Child, Preschool; C

1993
A phase I dose escalation of combination chemotherapy with granulocyte-macrophage-colony stimulating factor in patients with neuroblastoma.
    Cancer, 2000, Jun-15, Volume: 88, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplati

2000
Preclinical and clinical aspects on the use of amifostine as chemoprotector in neuroblastoma patients.
    Medical and pediatric oncology, 2001, Volume: 36, Issue:1

    Topics: Adolescent; Amifostine; Animals; Antineoplastic Agents; Bone Marrow Diseases; Carboplatin; Cell Divi

2001
Evaluation of catecholamine metabolites, mIBG scan, and bone marrow cytology as response markers in stage 4 neuroblastoma.
    Medical and pediatric oncology, 2001, Volume: 36, Issue:1

    Topics: 3-Iodobenzylguanidine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marro

2001
Single-agent ifosfamide in patients with recurrent neuroblastoma (ENSG study 2). European Neuroblastoma Study Group.
    Pediatric hematology and oncology, 1987, Volume: 4, Issue:2

    Topics: Bone Marrow Diseases; Child; Drug Evaluation; Female; Hematuria; Humans; Ifosfamide; Male; Neuroblas

1987

Other Studies

27 other studies available for ifosfamide and Neuroblastoma

ArticleYear
A report on second neo-plasms in seven children with solid tumors.
    Annali italiani di chirurgia, 2022, Volume: 92

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisp

2022
Extra-Adrenal Adult Neuroblastoma With Aberrant Germ Cell Marker Expression: Maturation After Chemotherapy as an Important Clue to a Challenging Diagnosis.
    International journal of surgical pathology, 2019, Volume: 27, Issue:5

    Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chemo

2019
The Use of Continuous Veno-Venous Hemodiafiltration in the Management of Ifosfamide-induced Encephalopathy: A Case Report.
    Journal of pediatric hematology/oncology, 2016, Volume: 38, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Child; Female; Hemodiafiltration; Humans; Ifosfam

2016
Outcomes of the POG 9340/9341/9342 trials for children with high-risk neuroblastoma: a report from the Children's Oncology Group.
    Pediatric blood & cancer, 2008, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Presch

2008
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:12

    Topics: Adrenal Gland Neoplasms; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2008
Advanced adult esthesioneuroblastoma successfully treated with cisplatin and etoposide alternated with doxorubicin, ifosfamide and vincristine.
    Journal of neuro-oncology, 2010, Volume: 98, Issue:1

    Topics: Adult; Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Doxorubicin; Endocrine Gland Neo

2010
Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma.
    European journal of cancer (Oxford, England : 1990), 2011, Volume: 47, Issue:4

    Topics: Abdominal Neoplasms; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child;

2011
Infratentorial brain metastases of pediatric non-epithelial malignant tumors: three case reports.
    Brain tumor pathology, 2011, Volume: 28, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin

2011
Neuroblastoma in an adult: case report.
    Revista medica de Chile, 2010, Volume: 138, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Neoplasms; Brain Neoplasms; Carboplatin

2010
The effect of N-acetylcysteine on the antitumor activity of ifosfamide.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Drug Interaction

2011
[Mobilization and collection of autologous peripheral blood stem cells by CIE or IEV protocol in children with malignant solid tumors].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2011, Volume: 13, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Epirubicin; Etoposide; Fema

2011
Application of high-dose rate (60)Co remote after-loading system for local recurrent neuroblastoma.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:11

    Topics: Abdominal Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Busulfan; Carbop

2011
[A case of retroperitoneal neuroblastoma in an adult with extensive bone marrow metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carboplatin; Dactinomy

2004
[Efficacy of chemotherapy regimen using ifosphamide and carboplatin on recurrent or refractory neuroblastoma].
    Ai zheng = Aizheng = Chinese journal of cancer, 2006, Volume: 25, Issue:12

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carbo

2006
Ifosfamide: should the honeymoon be over?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Child; Cisplatin; Cyclophosp

1995
[Combination chemotherapy of ifosfamide and etoposide for advanced neuroblastoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:14

    Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dr

1995
Ifosfamide in the treatment of pediatric malignancies.
    Seminars in oncology, 1996, Volume: 23, Issue:3 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

1996
Recurrent ifosfamide-induced hyponatraemia.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:14

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Cranial Nerve Neoplasms; Female; Humans; Hyponatremia

1997
Outcome prediction by molecular detection of minimal residual disease in bone marrow for advanced neuroblastoma.
    Medical and pediatric oncology, 2001, Volume: 36, Issue:1

    Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Mar

2001
Combination chemotherapy with ifosfamide and etoposide is effective in the treatment of central nervous system metastasis of childhood neuroblastoma.
    Cancer, 1992, Jun-15, Volume: 69, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Etoposide; Female;

1992
Cyclophosphamide versus ifosfamide in paediatric oncology.
    Lancet (London, England), 1990, Jul-28, Volume: 336, Issue:8709

    Topics: Adolescent; Child; Cyclophosphamide; Drug Administration Schedule; Humans; Ifosfamide; Neuroblastoma

1990
[Effects of mesna (2-mercaptoethane sodium sulfonate) in children with malignant disease receiving oxazaphosphorine chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1

    Topics: Bone Neoplasms; Child; Cyclophosphamide; Cystitis; Female; Hematuria; Humans; Ifosfamide; Leukemia;

1990
Short duration, high dose, alternating chemotherapy in metastatic neuroblastoma. (ENSG 3C induction regimen). The European Neuroblastoma Study Group.
    British journal of cancer, 1990, Volume: 62, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Dose-Response Relations

1990
Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:1

    Topics: Brain Neoplasms; Child, Preschool; Coma; Electroencephalography; Female; Humans; Ifosfamide; Kidney

1988
Ifosfamide in previously untreated disseminated neuroblastoma. Results of Study 3A of the European Neuroblastoma Study Group.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Cyclophosphamide; Femal

1988
[Ifosfamide treatment for children with malignant tumor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Female; Humans; Ifosfamide; Male; Mice; Mice, N

1987
Ifosfamide neurotoxicity in children.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Drug Evaluation; Female; Humans; Ifosfami

1987