Page last updated: 2024-10-29

ifosfamide and Leukemia, Myeloid, Acute

ifosfamide has been researched along with Leukemia, Myeloid, Acute in 16 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Etoposide has also been tested in a wide range of combination regimens, but for many of these combinations, relatively few patients are included, and some combinations have only been tested in patients who have undergone autologous transplants."2.48High-dose etoposide in allogeneic stem cell transplantation. ( Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH, 2012)
" Primary therapies were divided into four groups: radiotherapy alone, moderately dosed COPP/ABVD-like chemotherapies for intermediate and advanced stages and BEACOPP escalated."1.37Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. ( Diehl, V; Engert, A; Franklin, J; Hasenclever, D; Josting, A; Loeffler, M; Scholz, M, 2011)
"Primary mediastinal nonseminomatous germ cell tumors (NSGCT) have a worse prognosis than gonadal germ cell tumors (GCTs)."1.35Metastatic malignant teratoma arising from mediastinal nonseminomatous germ cell tumor: a case report. ( Carmichael, M; Collen, J; Wroblewski, T, 2008)
"One patient developed a secondary acute myeloid leukemia (s-AML) involving a chromosomal translocation t(11;19)(q23;p13."1.33Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer. ( Boehlke, I; Bokemeyer, C; Hartmann, JT; Kanz, L; Kollmannsberger, C; Kuczyk, M; Metzner, B; Schleicher, J; Schleucher, N; Wierecky, J, 2005)
"The interval between diagnosis of Ewing's sarcoma and the diagnosis of the SM was 17-78 months for the four AMLs, 96 months for the MDS and 82-136 months for the three sarcomas."1.30Second malignancies after treatment for Ewing's sarcoma: a report of the CESS-studies. ( Ahrens, S; Dunst, J; Harms, D; Jürgens, H; Paulussen, M; Rübe, C; Winkelmann, W; Zoubek, A, 1998)
"Six patients developed therapy-related acute myelogenous leukemia (t-AML)."1.30Acute myelogenous leukemia after treatment for malignant germ cell tumors in children. ( Behnisch, W; Göbel, U; Hilgenfeld, E; Schneider, DT; Schwabe, D; Wessalowski, R; Zoubek, A, 1999)
" A critical question in comparing an experimental treatment to a standard is how much increase in an adverse event rate is an acceptable trade-off for achieving a targeted improvement in efficacy, or vice versa."1.30Treatment comparisons based on two-dimensional safety and efficacy alternatives in oncology trials. ( Cheng, SC; Thall, PF, 1999)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's4 (25.00)18.2507
2000's7 (43.75)29.6817
2010's2 (12.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Kajita, N1
Saito, Y1
Makimoto, A1
Miyahara, S1
Yuza, Y1
Kim, YD1
Kim, KJ1
Lee, YH1
Scholz, M1
Engert, A1
Franklin, J1
Josting, A1
Diehl, V1
Hasenclever, D1
Loeffler, M1
Bruserud, O1
Reikvam, H1
Kittang, AO1
Ahmed, AB1
Tvedt, TH1
Sjo, M1
Hatfield, KJ1
Styczyński, J1
Wysocki, M1
Debski, R1
Balwierz, W1
Rokicka-Milewska, R1
Matysiak, M1
Balcerska, A1
Kowalczyk, J1
Wachowiak, J1
Sońta-Jakimczyk, D1
Chybicka, A1
Wierecky, J1
Kollmannsberger, C1
Boehlke, I1
Kuczyk, M1
Schleicher, J1
Schleucher, N1
Metzner, B1
Kanz, L1
Hartmann, JT1
Bokemeyer, C1
Takizawa, A1
Miura, T1
Fujinami, K1
Osada, Y1
Tanaka, M1
Maruta, I1
Abla, O1
Dror, Y1
Shago, M1
Schäfer, HS1
Becker, H1
Schmitt-Gräff, A1
Lübbert, M1
Collen, J1
Carmichael, M1
Wroblewski, T1
Norberg, B1
Holm, J1
Winqvist, E1
Wahlin, A1
Dunst, J1
Ahrens, S1
Paulussen, M1
Rübe, C1
Winkelmann, W1
Zoubek, A2
Harms, D1
Jürgens, H1
Schneider, DT1
Hilgenfeld, E1
Schwabe, D1
Behnisch, W1
Wessalowski, R1
Göbel, U1
Thall, PF1
Cheng, SC1
Büchner, T1
Kamanabroo, D1
Hiddemann, W1
Urbanitz, D1
Martens, AC1
de Groot, CJ1
Hagenbeek, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intensive Conditioning Regimen With Thiotepa Combined With Busulfan, Fludarabine and Cytarabine for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Myeloid Malignancies With Extramedullary Involvement[NCT06111612]50 participants (Anticipated)Observational2024-01-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ifosfamide and Leukemia, Myeloid, Acute

ArticleYear
High-dose etoposide in allogeneic stem cell transplantation.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:6

    Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chem

2012

Other Studies

15 other studies available for ifosfamide and Leukemia, Myeloid, Acute

ArticleYear
Double recurrence of double cancers: Rhabdomyosarcoma and secondary AML.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Fatal Outco

2020
Secondary leukemia in a child conceived using in vitro fertilization.
    Pediatrics international : official journal of the Japan Pediatric Society, 2008, Volume: 50, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Chemotherapy, Adjuvant; Child,

2008
Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:3

    Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine

2011
In vitro activity of oxazaphosphorines in childhood acute leukemia: preliminary report.
    Acta biochimica Polonica, 2002, Volume: 49, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Female; Glucose; Humans; Ifosfamide; In Vitro

2002
Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Etopo

2005
[A case of therapy-related leukemia/myelodysplastic syndrome following treatment of refractory testicular germ cell tumor].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2005, Volume: 96, Issue:7

    Topics: Adult; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Ci

2005
Translocation (X;10) in a child with therapy-related acute myeloid leukemia following chemotherapy for Ewing's Sarcoma.
    Cancer genetics and cytogenetics, 2007, Oct-15, Volume: 178, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Huma

2007
Granulocytic sarcoma of Core-binding Factor (CBF) acute myeloid leukemia mimicking pancreatic cancer.
    Leukemia research, 2008, Volume: 32, Issue:9

    Topics: Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; CA-19-9 Antig

2008
Metastatic malignant teratoma arising from mediastinal nonseminomatous germ cell tumor: a case report.
    Military medicine, 2008, Volume: 173, Issue:4

    Topics: Adult; Dacarbazine; Doxorubicin; Fatal Outcome; Humans; Ifosfamide; Leukemia, Myeloid, Acute; Male;

2008
Treatment of advanced bone marrow neoplasms with ifosfamide combinations.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphami

1984
Second malignancies after treatment for Ewing's sarcoma: a report of the CESS-studies.
    International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyclophos

1998
Acute myelogenous leukemia after treatment for malignant germ cell tumors in children.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:10

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Cisp

1999
Treatment comparisons based on two-dimensional safety and efficacy alternatives in oncology trials.
    Biometrics, 1999, Volume: 55, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Biometry; Clinical Trials as Topic; Humans; Ifosfamide; Leukemia,

1999
[Treatment of acute myeloblastic leukemia with cytosine arabinoside combined with daunorubicin or ifosfamide or thioguanine].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Ifosfamide; Leukemia, Myeloid, A

1978
Development and characterisation of a cyclophosphamide resistant variant of the BNML rat model for acute myelocytic leukaemia.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line; Cyclophosphamide; Disease Models, Animal; Dose-Response R

1991