ifosfamide has been researched along with Leucocythaemia in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article gives highlights of ongoing pediatric solid tumor and leukemia trials in the United States that use ifosfamide in combination with mesna." | 4.79 | Ongoing clinical studies of ifosfamide for pediatric cancer in the United States. ( Pratt, CB, 1996) |
| " 4-Hydroperoxyifosfamide appeared to be less cytotoxic against the leukemia cells than 4-hydroperoxycyclophosphamide." | 3.85 | Comparison of ( Blicharski, K; Fedoročko, P; Mazur, L; Mikeš, J; Niemeyer, U; Opydo-Chanek, M; Śladowska, K, 2017) |
| "Poor-risk solid tumors were treated with four courses of cyclophosphamide (4,200 mg/m2)/ doxorubicin (75 mg/m2), and three courses of ifosfamide (9,000 mg/m2)/etoposide (500 mg/m2)." | 2.69 | High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors. ( Bajorin, D; Cheung, NK; Heller, G; Kramer, K; Kushner, BH; Meyers, PA; Polyak, T; Wollner, N, 1998) |
| "Seven of the 15 patients with malignant lymphoma responded." | 2.64 | Isophosphamide therapy for hematologic malignancies in patients refractory to prior treatment. ( Bodey, GP; Freireich, EJ; Keating, MJ; McCredie, KB; Rodriguez, V; Valdivieso, M, 1978) |
| "Etoposide has also been tested in a wide range of combination regimens, but for many of these combinations, relatively few patients are included, and some combinations have only been tested in patients who have undergone autologous transplants." | 2.48 | High-dose etoposide in allogeneic stem cell transplantation. ( Ahmed, AB; Bruserud, O; Hatfield, KJ; Kittang, AO; Reikvam, H; Sjo, M; Tvedt, TH, 2012) |
| " The authors' multidimensional analysis model revealed that besides the total ifosfamide dose and co-administration of other toxic drugs, polymorphic locus of GSTP1 gene may be one of the factors determining a higher toxicity of the cytostatic agent." | 1.33 | Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children. ( Misiura, K; Zielińska, E; Zubowska, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (26.92) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Gökçe, F | 1 |
| Kaestli, A | 1 |
| Lohasz, C | 1 |
| de Geus, M | 1 |
| Kaltenbach, HM | 1 |
| Renggli, K | 1 |
| Bornhauser, B | 1 |
| Hierlemann, A | 1 |
| Modena, M | 1 |
| Teepen, JC | 1 |
| van Leeuwen, FE | 1 |
| Tissing, WJ | 1 |
| van Dulmen-den Broeder, E | 1 |
| van den Heuvel-Eibrink, MM | 1 |
| van der Pal, HJ | 1 |
| Loonen, JJ | 1 |
| Bresters, D | 1 |
| Versluys, B | 1 |
| Neggers, SJCMM | 1 |
| Jaspers, MWM | 1 |
| Hauptmann, M | 1 |
| van der Heiden-van der Loo, M | 1 |
| Visser, O | 1 |
| Kremer, LCM | 1 |
| Ronckers, CM | 1 |
| Opydo-Chanek, M | 1 |
| Śladowska, K | 1 |
| Blicharski, K | 1 |
| Mikeš, J | 1 |
| Fedoročko, P | 1 |
| Niemeyer, U | 1 |
| Mazur, L | 1 |
| Rigaud, C | 1 |
| Auperin, A | 1 |
| Jourdain, A | 1 |
| Haouy, S | 1 |
| Couec, ML | 1 |
| Aladjidi, N | 1 |
| Gandemer, V | 1 |
| Lambliotte, A | 1 |
| Plat, G | 1 |
| Landman-Parker, J | 1 |
| Michon, J | 1 |
| Leblanc, T | 1 |
| Patte, C | 1 |
| Minard-Colin, V | 1 |
| Say, R | 1 |
| Uzun, L | 1 |
| Yazar, S | 1 |
| Denizli, A | 1 |
| Hür, D | 1 |
| Yılmaz, F | 1 |
| Ersöz, A | 1 |
| Hoelzer, D | 1 |
| Walewski, J | 1 |
| Döhner, H | 1 |
| Viardot, A | 1 |
| Hiddemann, W | 2 |
| Spiekermann, K | 1 |
| Serve, H | 1 |
| Dührsen, U | 1 |
| Hüttmann, A | 1 |
| Thiel, E | 1 |
| Dengler, J | 1 |
| Kneba, M | 1 |
| Schaich, M | 1 |
| Schmidt-Wolf, IG | 1 |
| Beck, J | 1 |
| Hertenstein, B | 1 |
| Reichle, A | 1 |
| Domanska-Czyz, K | 1 |
| Fietkau, R | 1 |
| Horst, HA | 1 |
| Rieder, H | 1 |
| Schwartz, S | 1 |
| Burmeister, T | 1 |
| Gökbuget, N | 1 |
| Ramirez, MD | 1 |
| Mertens, AC | 1 |
| Esiashvili, N | 1 |
| Meacham, LR | 1 |
| Wasilewski-Masker, K | 1 |
| Bruserud, O | 1 |
| Reikvam, H | 1 |
| Kittang, AO | 1 |
| Ahmed, AB | 1 |
| Tvedt, TH | 1 |
| Sjo, M | 1 |
| Hatfield, KJ | 1 |
| Misiura, K | 2 |
| Szymanowicz, D | 1 |
| Kuśnierczyk, H | 1 |
| Wietrzyk, J | 1 |
| Opolski, A | 1 |
| Oriol, A | 1 |
| Ribera, JM | 1 |
| Brunet, S | 1 |
| del Potro, E | 1 |
| Abella, E | 1 |
| Esteve, J | 1 |
| Zielińska, E | 1 |
| Zubowska, M | 1 |
| Moleti, ML | 1 |
| Testi, AM | 1 |
| Giona, F | 1 |
| Malandruccolo, L | 1 |
| Pescarmona, E | 1 |
| Martino, P | 1 |
| Paoloni, F | 1 |
| Barberi, W | 1 |
| Palumbo, G | 1 |
| Mandelli, F | 1 |
| Foa, R | 1 |
| Gahrton, G | 1 |
| Carter, SK | 1 |
| Norberg, B | 1 |
| Holm, J | 1 |
| Winqvist, E | 1 |
| Wahlin, A | 1 |
| Hattori, M | 1 |
| Tanaka, M | 1 |
| Yamazaki, Y | 1 |
| Nakahara, Y | 1 |
| Tsushita, K | 1 |
| Utumi, M | 1 |
| Fields, KK | 1 |
| Elfenbein, GJ | 1 |
| Lazarus, HM | 1 |
| Cooper, BW | 1 |
| Perkins, JB | 1 |
| Creger, RJ | 1 |
| Ballester, OF | 1 |
| Hiemenz, JH | 1 |
| Janssen, WE | 1 |
| Zorsky, PE | 1 |
| Pratt, CB | 3 |
| Kushner, BH | 1 |
| Heller, G | 1 |
| Cheung, NK | 1 |
| Wollner, N | 1 |
| Kramer, K | 1 |
| Bajorin, D | 1 |
| Polyak, T | 1 |
| Meyers, PA | 1 |
| Rodriguez, V | 1 |
| McCredie, KB | 1 |
| Keating, MJ | 1 |
| Valdivieso, M | 1 |
| Bodey, GP | 2 |
| Freireich, EJ | 1 |
| Büchner, T | 1 |
| Urbanitz, D | 1 |
| Kamanabroo, D | 1 |
| Meister, R | 1 |
| Balleisen, L | 1 |
| Delvos, U | 1 |
| Lagrèze, EM | 1 |
| Schmitz-Huebner, U | 1 |
| Schulte, H | 1 |
| van de Loo, J | 1 |
| Rentschler, RE | 1 |
| Barlogie, B | 1 |
| Johnston, DA | 1 |
| Iwasaku-Fujimoto, M | 1 |
| Fujiwara, F | 1 |
| Todo, S | 1 |
| Morioka, Y | 1 |
| Imashuku, S | 1 |
| Brade, WP | 1 |
| Herdrich, K | 1 |
| Varini, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Study to Optimise Therapy of B-ALL, Burkitt's NHL and High-Grade Non-Hodgkin's Lymphoma in Adults (Amend 7)[NCT00199082] | Phase 4 | 650 participants (Anticipated) | Interventional | 2002-07-31 | Completed | ||
| Intensive Conditioning Regimen With Thiotepa Combined With Busulfan, Fludarabine and Cytarabine for Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Myeloid Malignancies With Extramedullary Involvement[NCT06111612] | 50 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| LINFOTARGAM: First-line Treatment With Dose-dense Chemotherapy Plus Rituximab (R-CHOP/14) and Highly Active Antiretroviral Therapy (HAART) in Patients With Diffuse Large B Cell Lymphoma (DLBCL) and Infection With the Human Immunodeficiency Virus (HIV)[NCT00466258] | Phase 4 | 50 participants (Anticipated) | Interventional | 2006-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for ifosfamide and Leucocythaemia
| Article | Year |
|---|---|
High-dose etoposide in allogeneic stem cell transplantation.
Topics: Adenine Nucleotides; Anthracyclines; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chem | 2012 |
Treatment of acute leukemia--advances in chemotherapy, immunotherapy, and bone marrow transplantation.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aminoacridines; Amsacrine; Anthraquinone | 1983 |
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as | 1980 |
Ongoing clinical studies of ifosfamide for pediatric cancer in the United States.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto | 1996 |
Current studies of ifosfamide for pediatric solid tumors and leukemia in the United States.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Chil | 1992 |
Ifosfamide studies for primary or recurrent pediatric malignant solid tumors and leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Humans; Ifosfamide; Leukemia; Lymphoma; Neopl | 1990 |
Ifosfamide--pharmacology, safety and therapeutic potential.
Topics: Animals; Biotransformation; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Evalu | 1985 |
9 trials available for ifosfamide and Leucocythaemia
| Article | Year |
|---|---|
Outcome of relapse in children and adolescents with B-cell non-Hodgkin lymphoma and mature acute leukemia: A report from the French LMB study.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carbopl | 2019 |
Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine- | 2014 |
Yield of Urinalysis Screening in Pediatric Cancer Survivors.
Topics: Adolescent; Adult; Child; Child, Preschool; Databases, Factual; Female; Follow-Up Studies; Glycosuri | 2016 |
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as | 1980 |
Maximum-tolerated doses of ifosfamide, carboplatin, and etoposide given over 6 days followed by autologous stem-cell rescue: toxicity profile.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neopl | 1995 |
High risk of leukemia after short-term dose-intensive chemotherapy in young patients with solid tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Dose-Res | 1998 |
Isophosphamide therapy for hematologic malignancies in patients refractory to prior treatment.
Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Cyclophosphamide; Drug Resistance; Femal | 1978 |
Intensification of remission induction therapy for acute nonlymphocytic leukemia (ANLL). I. Response and toxicity in four different regimens.
Topics: Acute Disease; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Ifosfamide; | 1979 |
Ifosfamide--pharmacology, safety and therapeutic potential.
Topics: Animals; Biotransformation; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Evalu | 1985 |
12 other studies available for ifosfamide and Leucocythaemia
| Article | Year |
|---|---|
Microphysiological Drug-Testing Platform for Identifying Responses to Prodrug Treatment in Primary Leukemia.
Topics: Child; Coculture Techniques; Humans; Ifosfamide; Leukemia; Liver; Prodrugs | 2023 |
Long-Term Risk of Subsequent Malignant Neoplasms After Treatment of Childhood Cancer in the DCOG LATER Study Cohort: Role of Chemotherapy.
Topics: Adolescent; Adult; Adult Survivors of Child Adverse Events; Aged; Antineoplastic Agents; Bone Neopla | 2017 |
Comparison of
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Cell Survival; Cyclopho | 2017 |
Bitargeting and ambushing nanotheranostics.
Topics: Antineoplastic Agents; Apoptosis; Drug Delivery Systems; HL-60 Cells; Humans; Ifosfamide; Leukemia; | 2014 |
Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).
Topics: Animals; Antineoplastic Agents; Carcinoma; Chromatography, High Pressure Liquid; Cytochrome P-450 En | 2002 |
Highly active antiretroviral therapy and outcome of AIDS-related Burkitt's lymphoma or leukemia. Results of the PETHEMA-LAL3/97 study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ant | 2005 |
Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Cyclophosph | 2005 |
CODOX-M/IVAC (NCI 89-C-41) in children and adolescents with Burkitt's leukemia/lymphoma and large B-cell lymphomas: a 15-year monocentric experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, P | 2007 |
Treatment of advanced bone marrow neoplasms with ifosfamide combinations.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphami | 1984 |
Detection of major and minor bcr/abl fusion gene transcripts in a patient with acute undifferentiated leukemia secondary to treatment with an alkylating agent.
Topics: Acute Disease; Alkylating Agents; Anemia, Sideroblastic; Base Sequence; Cell Transformation, Neoplas | 1995 |
In vivo perturbation of human marrow cell cycle progression by ifosfamide.
Topics: Bone Marrow; Cell Cycle; Cyclophosphamide; DNA, Neoplasm; Erythroblasts; Humans; Ifosfamide; Kinetic | 1978 |
[Effects of mesna (2-mercaptoethane sodium sulfonate) in children with malignant disease receiving oxazaphosphorine chemotherapy].
Topics: Bone Neoplasms; Child; Cyclophosphamide; Cystitis; Female; Hematuria; Humans; Ifosfamide; Leukemia; | 1990 |