Page last updated: 2024-10-29

ifosfamide and Kidney Failure

ifosfamide has been researched along with Kidney Failure in 9 studies

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"To explore the effect of high-dose ifosfamide in first-line treatment for patients < or = 40 years of age with nonmetastatic osteosarcoma of the extremity."9.11Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. ( Alvegard, TA; Bacci, G; Bernini, G; Bertoni, F; Böhling, T; Brosjö, O; Capanna, R; Comandone, A; Del Prever, AB; Ferrari, S; Longhi, A; Mercuri, M; Müller, C; Picci, P; Ruggieri, P; Saeter, G; Smeland, S; Tienghi, A; Wiebe, T, 2005)
"Although chemotherapy for advanced bladder cancer has historically been based on cisplatin-based combination regimens, the limitations of these regimens both in terms of efficacy and toxicity are now widely appreciated."6.39Ifosfamide in the treatment of bladder cancer. ( Roth, BJ, 1996)
"To explore the effect of high-dose ifosfamide in first-line treatment for patients < or = 40 years of age with nonmetastatic osteosarcoma of the extremity."5.11Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups. ( Alvegard, TA; Bacci, G; Bernini, G; Bertoni, F; Böhling, T; Brosjö, O; Capanna, R; Comandone, A; Del Prever, AB; Ferrari, S; Longhi, A; Mercuri, M; Müller, C; Picci, P; Ruggieri, P; Saeter, G; Smeland, S; Tienghi, A; Wiebe, T, 2005)
"The purpose of this study was to make evidence-based recommendations regarding the mode, dosage and schedule of delivery of concomitant mesna (sodium-2-mercaptoethanesulfonate) to protect against ifosfamide-induced uroepithelial toxicity."2.40Use of mesna to prevent ifosfamide-induced urotoxicity. ( Moore, MJ; Siu, LL, 1998)
"Although chemotherapy for advanced bladder cancer has historically been based on cisplatin-based combination regimens, the limitations of these regimens both in terms of efficacy and toxicity are now widely appreciated."2.39Ifosfamide in the treatment of bladder cancer. ( Roth, BJ, 1996)
" There was no compelling evidence for increased toxicity of doxorubicin when given at 100% versus 50% dosing (full dose: 20 mg/m(2) day x 3), but the number of patients analyzed was small."1.35Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group. ( Breslow, NE; Feusner, JH; Green, DM; Norkool, PA; Ritchey, ML; Takashima, JR, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Khandelwal, P1
Govindarajan, S1
Bagga, A1
Arjmand, A3
Mashhadi, M3
Kaveh, A3
Kamranfar, F3
Seydi, E3
Pourahmad, J3
Yin, ZM1
Yu, AJ1
Wu, MJ1
Fang, J1
Liu, LF1
Zhu, JQ1
Yu, H1
Ferrari, S1
Smeland, S1
Mercuri, M1
Bertoni, F1
Longhi, A1
Ruggieri, P1
Alvegard, TA1
Picci, P1
Capanna, R1
Bernini, G1
Müller, C1
Tienghi, A1
Wiebe, T1
Comandone, A1
Böhling, T1
Del Prever, AB1
Brosjö, O1
Bacci, G1
Saeter, G1
Schlondorff, JS1
Mendez, GP1
Rennke, HG1
Magee, CC1
Feusner, JH1
Ritchey, ML1
Norkool, PA1
Takashima, JR1
Breslow, NE1
Green, DM1
Roth, BJ1
Liubimova, NV1
Kumykova, ZhKh1
Kushlinskiĭ, NE1
Kasumov, ChM1
Durnov, LA1
Siu, LL1
Moore, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Observational Study on the Treatment of Patients With Localized Osteosarcoma[NCT04890067]120 participants (Anticipated)Observational2021-07-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for ifosfamide and Kidney Failure

ArticleYear
Management and outcomes in children with lupus nephritis in the developing countries.
    Pediatric nephrology (Berlin, Germany), 2023, Volume: 38, Issue:4

    Topics: Child; Developing Countries; Humans; Ifosfamide; Lupus Nephritis; Renal Dialysis; Renal Insufficienc

2023
Ifosfamide in the treatment of bladder cancer.
    Seminars in oncology, 1996, Volume: 23, Issue:3 Suppl 6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo

1996
Use of mesna to prevent ifosfamide-induced urotoxicity.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1998, Volume: 6, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Drug Administration Schedule; Humans; Ifosfamide; Kidney; Mesna;

1998

Trials

1 trial available for ifosfamide and Kidney Failure

ArticleYear
Neoadjuvant chemotherapy with high-dose Ifosfamide, high-dose methotrexate, cisplatin, and doxorubicin for patients with localized osteosarcoma of the extremity: a joint study by the Italian and Scandinavian Sarcoma Groups.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-01, Volume: 23, Issue:34

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Pre

2005

Other Studies

5 other studies available for ifosfamide and Kidney Failure

ArticleYear
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Mitochondrial Transplantation Therapy against Ifosfamide Induced Toxicity on Rat Renal Proximal Tubular Cells.
    Drug research, 2023, Volume: 73, Issue:2

    Topics: Animals; Glutathione; Ifosfamide; Kidney; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Pot

2023
Effects and toxicity of neoadjuvant chemotherapy preoperative followed by adjuvant chemoradiation in small cell neurdendocrine cervical carcinoma.
    European journal of gynaecological oncology, 2015, Volume: 36, Issue:3

    Topics: Adult; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Neuroendo

2015
Electrolyte abnormalities and progressive renal failure in a cancer patient.
    Kidney international, 2007, Volume: 71, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; C

2007
Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Dactinomycin; Do

2008
[Biochemical parameters in the diagnosis of nephrotoxicity of antineoplastic chemotherapy in children].
    Voprosy onkologii, 1997, Volume: 43, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Cispl

1997