Page last updated: 2024-10-29

ifosfamide and Hepatoblastoma

ifosfamide has been researched along with Hepatoblastoma in 11 studies

Hepatoblastoma: A malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The Cooperative German Paediatric Liver Tumour Study HB89 was conceived to evaluate the efficiency and toxicity of ifosfamide, cisplatin and doxorubicin (IPA) in children with resectable and non-resectable hepatoblastoma (HB) and to determine late sequelae including tubular nephropathy of tumour treatment."9.08Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology. ( Bode, U; Bürger, D; Byrd, DJ; Erttmann, R; Harms, D; Hecker, H; Mildenberger, H; von Schweinitz, D; Weinel, P, 1997)
"Hepatoblastoma is the most common primary malignant liver tumor affecting infants and young children."5.30Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin, and etoposide in heterotransplanted hepatoblastoma. ( Fuchs, J; Haindl, J; Leuschner, I; von Schweinitz, D; Wenderoth, M, 1998)
"The Cooperative German Paediatric Liver Tumour Study HB89 was conceived to evaluate the efficiency and toxicity of ifosfamide, cisplatin and doxorubicin (IPA) in children with resectable and non-resectable hepatoblastoma (HB) and to determine late sequelae including tubular nephropathy of tumour treatment."5.08Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology. ( Bode, U; Bürger, D; Byrd, DJ; Erttmann, R; Harms, D; Hecker, H; Mildenberger, H; von Schweinitz, D; Weinel, P, 1997)
"The purpose of the German HB99 trial (1999-2008) for hepatoblastoma (HB), was primarily to analyse the effect of high dose (HD) chemotherapy with carboplatin/etoposide (CE) in high risk (HR) patients with extended tumors, vessel involvement, extrahepatic tumor or distant metastases."3.91High Dose Chemotherapy with Autologous Stem Cell Transplantation in Hepatoblastoma does not Improve Outcome. Results of the GPOH Study HB99. ( Häberle, B; Maxwell, R; Schmid, I; Schweinitz, DV, 2019)
"To evaluate the efficacy and safety of the ICE regimen (iphosphamide + carboplatin + etoposide) used in treating children with hepatoblastoma in the Shanghai Children's Medical Center."3.75[Clinical observation on the treatment outcome of 14 children with hepatoblastoma in a single medical center]. ( Chen, J; Dong, L; Gu, LJ; Jiang, H; Pan, C; Tang, JY; Xue, HL; Ye, QD; Zhou, M, 2009)
" Surgical biopsy performed after the first IPA (ifosfamide, cisplatin, doxorubicin) course showed hepatoblastoma with macrotrabecular variant."3.73Unresectable multifocal hepatoblastoma with cardiac extension: excellent response with HB-94 chemotherapy protocol. ( Anik, Y; Corapçioğlu, F; Sarper, N; Tugay, M; Ural, D; Yildiz, K, 2006)
"Hepatoblastoma is the most common primary malignant liver tumor affecting infants and young children."1.30Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin, and etoposide in heterotransplanted hepatoblastoma. ( Fuchs, J; Haindl, J; Leuschner, I; von Schweinitz, D; Wenderoth, M, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's4 (36.36)29.6817
2010's3 (27.27)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Hu, H1
Zhang, W1
Zhang, Y1
Gao, Y1
Zhi, T1
Li, F1
Li, J1
Gu, H1
Liao, R1
Wu, R1
Huang, D1
Häberle, B1
Maxwell, R1
Schweinitz, DV1
Schmid, I1
Natarajan, E1
Auerbach, C1
Cheron, R1
Pashankar, F1
Hiyama, E2
Hishiki, T2
Watanabe, K2
Ida, K2
Yano, M2
Oue, T2
Iehara, T1
Hoshino, K1
Koh, K1
Tanaka, Y1
Kurihara, S1
Ueda, Y1
Onitake, Y1
Gutweiler, JR1
Yu, DC1
Kim, HB1
Kozakewich, HP1
Marcus, KJ1
Shamberger, RC1
Weldon, CB1
Pan, C1
Tang, JY1
Chen, J1
Xue, HL1
Dong, L1
Zhou, M1
Jiang, H1
Ye, QD1
Gu, LJ1
Matsunaga, T1
Sasaki, F1
Horie, H1
Kondo, S1
Tajiri, T1
Kamimatsuse, A1
Ohnuma, N1
Fuchs, J2
Rydzynski, J1
Hecker, H2
Mildenberger, H2
Bürger, D2
Harms, D2
V Schweinitz, D1
Sarper, N1
Corapçioğlu, F1
Anik, Y1
Ural, D1
Yildiz, K1
Tugay, M1
von Schweinitz, D2
Byrd, DJ1
Weinel, P1
Bode, U1
Erttmann, R1
Wenderoth, M1
Haindl, J1
Leuschner, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Combined Modality Therapy in Hepatoblastoma: South Egypt Cancer Institute Experience[NCT02557750]35 participants (Anticipated)Observational2016-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ifosfamide and Hepatoblastoma

ArticleYear
Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology.
    European journal of cancer (Oxford, England : 1990), 1997, Volume: 33, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Child, Preschool; Cis

1997

Other Studies

10 other studies available for ifosfamide and Hepatoblastoma

ArticleYear
Individualized chemotherapy and efficacy analysis of hepatoblastoma in children.
    Pediatric blood & cancer, 2024, Volume: 71, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Cisplatin; Cyclophosphamide; Eto

2024
High Dose Chemotherapy with Autologous Stem Cell Transplantation in Hepatoblastoma does not Improve Outcome. Results of the GPOH Study HB99.
    Klinische Padiatrie, 2019, Volume: 231, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Combined Modality Therapy; D

2019
Sustained Remission After Maintenance Irinotecan in Patient With Multiply Relapsed Hepatoblastoma.
    Journal of pediatric hematology/oncology, 2020, Volume: 42, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Chemotherapy, Adjuvant; D

2020
Resectability and tumor response after preoperative chemotherapy in hepatoblastoma treated by the Japanese Study Group for Pediatric Liver Tumor (JPLT)-2 protocol.
    Journal of pediatric surgery, 2016, Volume: 51, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Ci

2016
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma.
    Journal of pediatric surgery, 2008, Volume: 43, Issue:12

    Topics: Adrenal Gland Neoplasms; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2008
[Clinical observation on the treatment outcome of 14 children with hepatoblastoma in a single medical center].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2009, Volume: 11, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Etoposide; Fem

2009
Outcome of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor (JPLT) protocol-2: report from the JPLT.
    Pediatric surgery international, 2011, Volume: 27, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Com

2011
The influence of preoperative chemotherapy and surgical technique in the treatment of hepatoblastoma--a report from the German Cooperative Liver Tumour Studies HB 89 and HB 94.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2002, Volume: 12, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

2002
Unresectable multifocal hepatoblastoma with cardiac extension: excellent response with HB-94 chemotherapy protocol.
    Journal of pediatric hematology/oncology, 2006, Volume: 28, Issue:6

    Topics: alpha-Fetoproteins; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Calcinosi

2006
Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin, and etoposide in heterotransplanted hepatoblastoma.
    Cancer, 1998, Dec-01, Volume: 83, Issue:11

    Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Carboplatin; Cell Division; Child, Preschool; Ci

1998