Page last updated: 2024-10-29

ifosfamide and HIV Coinfection

ifosfamide has been researched along with HIV Coinfection in 12 studies

Research Excerpts

ExcerptRelevanceReference
"The toxicity of dose-intensive regimens used for Burkitt lymphoma prompted modification of cyclophosphamide, vincristine, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, and high-dose cytarabine (CODOX-M/IVAC) for HIV-positive patients."5.20AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma. ( Ambinder, R; Baiocchi, R; Cesarman, E; Kaplan, L; Lee, JY; Noy, A; Ratner, L; Reid, E; Wagner-Johnston, N, 2015)
"Treatment options for Burkitt's lymphoma involve complex chemotherapy regimens that contain as many as 10 cytotoxic agents."2.41Challenges in the management of Burkitt's lymphoma. ( Levine, AM, 2002)
"Burkitt lymphoma is an aggressive B cell malignancy accounting for 1-2% of all adult lymphomas."1.48Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens. ( Baars, JW; Brouwer, R; Chamuleau, MED; de Jong, D; de Wreede, LC; Demandt, AMP; Doorduijn, JK; Hardi, L; Kersten, MJ; Kluin, PM; Nijland, M; Oosten, LEM; Siemes, C; Smeekes, OS; Stevens, WBC; Thielen, FW; Uyl-de Groot, CA; van Imhoff, GW; Veelken, H, 2018)
" Much attention has focussed on pharmacokinetic interactions attributable to effects on hepatic microsomal enzymes, but not on competition for the renal organic anion transport system."1.43The pharmacokinetics of high-dose methotrexate in people living with HIV on antiretroviral therapy. ( Bendle, M; Boffito, M; Bower, M; Dalla Pria, A; Ramaswami, R, 2016)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oosten, LEM1
Chamuleau, MED1
Thielen, FW1
de Wreede, LC1
Siemes, C1
Doorduijn, JK1
Smeekes, OS1
Kersten, MJ1
Hardi, L1
Baars, JW1
Demandt, AMP1
Stevens, WBC1
Nijland, M1
van Imhoff, GW1
Brouwer, R1
Uyl-de Groot, CA1
Kluin, PM1
de Jong, D1
Veelken, H1
Reid, EG1
Looney, D1
Maldarelli, F1
Noy, A2
Henry, D1
Aboulafia, D1
Ramos, JC1
Sparano, J1
Ambinder, RF1
Lee, J1
Cesarman, E2
Yahyaei, S1
Mitsuyasu, R1
Wachsman, W1
Lee, JY1
Ambinder, R1
Baiocchi, R1
Reid, E1
Ratner, L1
Wagner-Johnston, N1
Kaplan, L1
Dalla Pria, A1
Bendle, M1
Ramaswami, R1
Boffito, M1
Bower, M1
Saha, D1
Basu, A1
Maiti, A1
Rodriguez, E1
Berretta, M1
Zanet, E1
Taibi, R1
Martellotta, F1
Pavone, P1
Bearz, A1
Gobitti, C1
Ciancia, EM1
Canzonieri, V1
Tirelli, U1
Govender, PS1
Barnes, JA1
Lacasce, AS1
Feng, Y1
Toomey, CE1
Neuberg, D1
Michaelson, JS1
Hochberg, EP1
Abramson, JS1
Levine, AM1
Fan, SK1
Wang, YG1
Shimomura, A1
Lilienfeld-Toal, Mv1
Balta, Z1
Schroers, E1
Schmidt-Wolf, IG1
Büttner, R1
Rücker, Av1
Gütgemann, I1
Jambusaria, A1
Shafer, D1
Wu, H1
Al-Saleem, T1
Perlis, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy Pilot Trial of the Anti-Viral and Anti-Tumor Activity of Velcade Combined With (R)ICE in Subjects With EBV and/or HHV-8 Positive Relapsed/Refractory AIDS-Associated Non-Hodgkin's Lymphoma[NCT00598169]Phase 123 participants (Actual)Interventional2007-11-30Completed
Prospective Phase II Study of a High Dose, Short Course Regimen (R-CODOX-M/IVAC) Including CNS Penetration and Intensive IT Prophylaxis in HIV-Associated Burkitt's and Atypical Burkitt's Lymphoma[NCT00392834]Phase 234 participants (Actual)Interventional2006-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival (OS) at 1 Year

(NCT00392834)
Timeframe: 1 year post treatment

InterventionCumulative proportion surviving at 1 yr (Number)
Regimen A (R-CODOX-M Chemotherapy)1.0
Regimen B (Rituximab and IVAC Chemotherapy)0.82

Reviews

2 reviews available for ifosfamide and HIV Coinfection

ArticleYear
Leiomyosarcoma of the parotid gland in an HIV-positive patient: therapeutic approach, clinical course and review of the literature.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Biomar

2009
Challenges in the management of Burkitt's lymphoma.
    Clinical lymphoma, 2002, Volume: 3 Suppl 1

    Topics: Adult; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly A

2002

Trials

2 trials available for ifosfamide and HIV Coinfection

ArticleYear
Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas.
    Blood advances, 2018, 12-26, Volume: 2, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; APOBEC-3G Deaminase; Bortezomib; Carbop

2018
AMC 048: modified CODOX-M/IVAC-rituximab is safe and effective for HIV-associated Burkitt lymphoma.
    Blood, 2015, Jul-09, Volume: 126, Issue:2

    Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antir

2015

Other Studies

8 other studies available for ifosfamide and HIV Coinfection

ArticleYear
Treatment of sporadic Burkitt lymphoma in adults, a retrospective comparison of four treatment regimens.
    Annals of hematology, 2018, Volume: 97, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Carmustin

2018
The pharmacokinetics of high-dose methotrexate in people living with HIV on antiretroviral therapy.
    Cancer chemotherapy and pharmacology, 2016, Volume: 77, Issue:3

    Topics: Adult; Aged; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cycl

2016
Primary proximal epithelioid sarcoma of the lung successfully treated with pneumonectomy and adjuvant chemotherapy.
    BMJ case reports, 2016, Apr-04, Volume: 2016

    Topics: Adult; Chemotherapy, Adjuvant; Doxorubicin; Hemoptysis; HIV Infections; Humans; Ifosfamide; Lung Neo

2016
Atypical presentation of angiosarcoma of the scalp in the setting of human immunodeficiency virus (HIV).
    World journal of surgical oncology, 2009, Dec-18, Volume: 7

    Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; CD4 Lymphocyte Count; Combine

2009
Evaluation of the addition of rituximab to CODOX-M/IVAC for Burkitt's lymphoma: a retrospective analysis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherap

2011
Decision-theoretic designs for dose-finding clinical trials with multiple outcomes.
    Statistics in medicine, 2006, May-30, Volume: 25, Issue:10

    Topics: Algorithms; Anti-HIV Agents; Antineoplastic Agents, Alkylating; Child, Preschool; Clinical Trials, P

2006
Absent immunoglobulins in HIV-related Burkitt lymphoma/leukaemia.
    Annals of hematology, 2008, Volume: 87, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; B-Lymphocytes

2008
Cutaneous plasmablastic lymphoma.
    Journal of the American Academy of Dermatology, 2008, Volume: 58, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Doxorubicin; Etoposid

2008