ifosfamide has been researched along with Germinoma in 96 studies
Germinoma: A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)
Excerpt | Relevance | Reference |
---|---|---|
" Based on the limited clinical impact and the high incidence of rhGM-CSF-related toxicity that required growth factor discontinuation, the routine administration of rhGM-CSF to prevent neutropenia and infection after ifosfamide-based chemotherapy for GCT patients is not recommended." | 5.08 | Recombinant human granulocyte-macrophage colony-stimulating factor as an adjunct to conventional-dose ifosfamide-based chemotherapy for patients with advanced or relapsed germ cell tumors: a randomized trial. ( Bajorin, DF; Bokemeyer, C; Bosl, GJ; Demetri, GD; Einhorn, LH; Kantoff, PW; Nichols, CR; Schmoll, HJ, 1995) |
"Phase II studies conducted in Europe and the USA on pediatric solid tumors have shown that ifosfamide, as a single agent, is an active drug against a variety of neoplasms - rhabdomyosarcoma (RMS), some non-RMS soft tissue sarcomas, Wilms' tumor, bone sarcomas and neuroblastoma." | 4.82 | Ifosfamide in pediatric solid tumors. ( Bisogno, G; Carli, M; Passone, E; Perilongo, G, 2003) |
"The teratocarcinoma cell line 833K and its relatively cisplatin-resistant subline 833K/63CP 10 were used to assess the cytotoxicity of paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ), cisplatin, and 4-hydroxyperoxycyclophosphamide quantitatively." | 4.79 | Paclitaxel in germ cell cancer. ( Bajorin, DF; Bosl, GJ; Chou, TC; Hutter, H; Motzer, RJ; Schwartz, L, 1995) |
"The activity of ifosfamide in genitourinary malignancies has been documented in testicular cancer and bladder cancer." | 4.79 | The role of ifosfamide in the treatment of testicular and urothelial malignancies. ( Roth, BJ, 1996) |
"Patients with localized germinoma received either CSI or 2 courses of carboplatin and etoposide alternating with etoposide and ifosfamide, followed by local radiotherapy." | 3.79 | SIOP CNS GCT 96: final report of outcome of a prospective, multinational nonrandomized trial for children and adults with intracranial germinoma, comparing craniospinal irradiation alone with chemotherapy followed by focal primary site irradiation for pat ( Alapetite, C; Calaminus, G; Frappaz, D; Garrè, ML; Kortmann, R; Nicholson, JC; Patte, C; Ricardi, U; Saran, F; Worch, J, 2013) |
" Six patients with solitary pure germinomas were treated with three or four cycles of cisplatin and etoposide (EP regimen) followed by 24-Gy local radiation therapy." | 3.70 | Induction chemotherapy followed by reduced-volume radiation therapy for newly diagnosed central nervous system germinoma. ( Abe, H; Fujieda, K; Ikeda, J; Ishii, N; Kato, T; Sawamura, Y; Shirato, H; Tada, M, 1998) |
"Following etoposide and cisplatin with or without ifosfamide, 13 patients with nondisseminated disease received involved-field irradiation of 24 Gy in 12 fractions within 3 weeks and 2 patients with disseminated germinoma received 24 Gy craniospinal irradiation (CSI)." | 3.70 | Preirradiation evaluation and technical assessment of involved-field radiotherapy using computed tomographic (CT) simulation and neoadjuvant chemotherapy for intracranial germinoma. ( Ikeda, J; Kitamura, K; Miyasaka, K; Sawamura, Y; Shirato, H; Suzuki, K, 1999) |
" The results however, did not show expected treatment efficacy and we raise the idea of paclitaxel dosage relevance in TIP." | 2.71 | Paclitaxel plus ifosfamide and cisplatin in second-line treatment of germ cell tumors: a phase II study. ( Hlavatá, Z; Koza, I; Mardiak, J; Mego, M; Obertová, J; Recková, M; Sálek, T; Sycová-Milá, Z, 2005) |
" Since such treatment is relatively toxic, pharmacokinetic characteristics of total and ultrafiltered platinum, representing different species of platinum complexes formed, were investigated in 29 patients in relation to toxicity." | 2.70 | Toxicity of high-dose carboplatin: ultrafiltered and not total plasma pharmacokinetics is of clinical relevance. ( Beyer, J; Jaehde, U; Kloft, C; Siegert, W, 2002) |
" The AUC of carboplatin measured in serum was lower than the target AUC; this may be related to underestimation of the glomerular filtration rate used in the dosing formula." | 2.69 | Sequential dose-intensive paclitaxel, ifosfamide, carboplatin, and etoposide salvage therapy for germ cell tumor patients. ( Bains, M; Bajorin, DF; Bosl, GJ; Flombaum, C; Macapinlac, HA; Mariani, T; Mazumdar, M; Motzer, RJ; Reich, L; Sheinfeld, J; Tong, WP, 2000) |
"Of 21 patients with testicular tumors who could be evaluated, 10 (47%) achieved a CR." | 2.68 | High dose chemotherapy with ifosfamide, carboplatin, and etoposide combined with autologous bone marrow transplantation for the treatment of poor-prognosis germ cell tumors and metastatic trophoblastic disease in adults. ( André, T; Bonnak, H; Bouleuc, C; Donsimoni, R; Esteso, A; Firmin, C; Gerota, J; Izrael, V; Lotz, JP; Merad, Z, 1995) |
"Ifosfamide has always had significant single-agent activity in patients with germ cell tumors." | 2.42 | Ifosfamide in germ cell tumors. ( Einhorn, LH, 2003) |
" An objective causality assessment revealed that an adverse drug reaction was probable." | 2.42 | Vascular neurotoxicity following chemotherapy with cisplatin, ifosfamide, and etoposide. ( Bogdahn, U; Dietrich, J; Marienhagen, J; Schalke, B; Schlachetzki, F, 2004) |
"Ifosfamide has been found to have antineoplastic activity in a variety of solid tumors." | 2.39 | The role of ifosfamide in germ cell tumors and small cell lung cancer. ( Nichols, CR, 1995) |
"For patients with far advanced testicular cancer, who only have a chance of long-term cure in the range of 40% to 50% by standard induction chemotherapy, the German Testicular Cancer Study Group has shown that the application of GM-CSF after PEI chemotherapy has allowed the increase of dose intensity of this three-drug regimen by a factor of 1." | 2.39 | The role of granulocyte-macrophage colony-stimulating factor in the treatment of germ cell tumors. German Testicular Cancer Study Group. ( Bokemeyer, C; Clemm, C; Harstrick, A; Illiger, HJ; Link, H; Metzner, B; Ostermann, H; Rüther, U; Schmoll, HJ; Siegert, W, 1994) |
"Ifosfamide has single-agent activity comparable to etoposide in very poor-prognosis, cisplatin-refractory disease." | 2.39 | Ifosfamide in the treatment of germ cell tumors. ( Nichols, CR, 1996) |
"Suprasellar germinomas are rare intracranial neoplasms, which mainly occur in children and adolescents and manifest with endocrine symptoms and/or compression syndromes." | 1.34 | [Long-term follow-up of patients with suprasellar germinomas]. ( Bauditz, J; Lochs, H; Ventz, M, 2007) |
"One patient developed a secondary acute myeloid leukemia (s-AML) involving a chromosomal translocation t(11;19)(q23;p13." | 1.33 | Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer. ( Boehlke, I; Bokemeyer, C; Hartmann, JT; Kanz, L; Kollmannsberger, C; Kuczyk, M; Metzner, B; Schleicher, J; Schleucher, N; Wierecky, J, 2005) |
"Six patients developed therapy-related acute myelogenous leukemia (t-AML)." | 1.30 | Acute myelogenous leukemia after treatment for malignant germ cell tumors in children. ( Behnisch, W; Göbel, U; Hilgenfeld, E; Schneider, DT; Schwabe, D; Wessalowski, R; Zoubek, A, 1999) |
" Poor performance status and prior radiotherapy were risk factors for fatal adverse effects." | 1.30 | [Treatment of advanced testicular cancer and toxicity of chemotherapy]. ( Kawakita, M; Matsuda, T; Terachi, T; Yoshida, O, 1999) |
"The standard treatment of dysgerminoma is currently first line chemotherapy followed by relatively low-dose and limited irradiation; the standard treatment of non-seminomatous cerebral germ cell tumor is chemotherapy, the study of which is warranted with the aim to decrease the toxicity and to increase the efficacy." | 1.29 | [Cerebral germ cell tumors in adults. A retrospective study of 19 cases]. ( Agranat, P; Epardeau, B; Extra, JM; Jedynak, P; Mignot, L, 1995) |
"These were neuroepithelioma, lymphoma, desmoplastic small-cell tumor, melanoma, and clear-cell sarcoma." | 1.29 | Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site. ( Bosl, GJ; Chaganti, RS; Mazumdar, M; Motzer, RJ; Reuter, VE; Rodriguez, E, 1995) |
" Dose-response curves for cisplatin (3-30 000 nmol) combined with non-toxic silibinin doses (7." | 1.29 | Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity. ( Bokemeyer, C; Dunn, T; Fels, LM; Gaedeke, J; Lentzen, H; Schmoll, HJ; Stolte, H; Voigt, W, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 59 (61.46) | 18.2507 |
2000's | 31 (32.29) | 29.6817 |
2010's | 6 (6.25) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Calaminus, G | 1 |
Kortmann, R | 1 |
Worch, J | 1 |
Nicholson, JC | 1 |
Alapetite, C | 2 |
Garrè, ML | 1 |
Patte, C | 3 |
Ricardi, U | 1 |
Saran, F | 1 |
Frappaz, D | 2 |
Inai, H | 1 |
Kawai, K | 1 |
Kojima, T | 1 |
Joraku, A | 1 |
Shimazui, T | 1 |
Yamauchi, A | 1 |
Miyagawa, T | 1 |
Endo, T | 1 |
Fukuhara, Y | 1 |
Miyazaki, J | 1 |
Uchida, K | 1 |
Nishiyama, H | 1 |
Fukuoka, K | 1 |
Yanagisawa, T | 1 |
Watanabe, Y | 1 |
Suzuki, T | 1 |
Matsutani, M | 1 |
Kuji, I | 1 |
Nishikawa, R | 1 |
Nodomi, S | 1 |
Umeda, K | 1 |
Ueno, H | 1 |
Saida, S | 1 |
Hiramatsu, H | 1 |
Funaki, T | 1 |
Arakawa, Y | 1 |
Mizowaki, T | 1 |
Adachi, S | 1 |
Heike, T | 1 |
Pauly-Takacs, K | 1 |
Moulin, CJ | 1 |
Estlin, EJ | 1 |
Brisse, H | 1 |
Raquin, MA | 1 |
Gaboriaud, G | 1 |
Carrie, C | 1 |
Habrand, JL | 1 |
Thiesse, P | 1 |
Cuilliere, JC | 1 |
Bernier, V | 1 |
Ben-Hassel, M | 1 |
Baranzelli, MC | 2 |
Bouffet, E | 2 |
Hinton, S | 1 |
Catalano, PJ | 2 |
Einhorn, LH | 8 |
Nichols, CR | 9 |
David Crawford, E | 1 |
Vogelzang, N | 1 |
Trump, D | 1 |
Loehrer, PJ | 4 |
Bokemeyer, C | 12 |
Schleucher, N | 3 |
Metzner, B | 6 |
Thomas, M | 1 |
Rick, O | 6 |
Schmoll, HJ | 10 |
Kollmannsberger, C | 4 |
Boehlke, I | 2 |
Kanz, L | 4 |
Hartmann, JT | 4 |
Motzer, RJ | 10 |
Sheinfeld, S | 1 |
Schöffski, P | 1 |
Schleicher, J | 3 |
Beyer, J | 13 |
Hossfeld, D | 1 |
Berdel, WE | 1 |
Andreesen, R | 1 |
Carli, M | 1 |
Passone, E | 1 |
Perilongo, G | 1 |
Bisogno, G | 1 |
Dietrich, J | 1 |
Marienhagen, J | 1 |
Schalke, B | 1 |
Bogdahn, U | 1 |
Schlachetzki, F | 1 |
Kunishio, K | 1 |
Okada, M | 1 |
Miyake, K | 1 |
Matsumoto, Y | 1 |
Nagao, S | 1 |
Nishiyama, Y | 1 |
Ohkawa, M | 1 |
Tanji, S | 1 |
Obara, W | 1 |
Sugimura, J | 1 |
Ohmori, S | 1 |
Matsushita, Y | 1 |
Tokunaga, H | 1 |
Konda, R | 1 |
Fujioka, T | 1 |
Murai, K | 1 |
Ishida, Y | 1 |
Sakura, M | 1 |
Tsukamoto, T | 3 |
Yonese, J | 2 |
Nakaishi, M | 1 |
Ohkubo, Y | 1 |
Maezawa, T | 1 |
Takimoto, K | 1 |
Fukui, I | 2 |
Nakagawa, K | 1 |
Okumura, S | 1 |
Ishikawa, Y | 1 |
Aoki, N | 1 |
Wierecky, J | 1 |
Kuczyk, M | 1 |
El-Helw, L | 1 |
Coleman, RE | 1 |
Kondagunta, GV | 1 |
Bacik, J | 2 |
Donadio, A | 1 |
Bajorin, D | 3 |
Marion, S | 1 |
Sheinfeld, J | 3 |
Bosl, GJ | 9 |
Mardiak, J | 2 |
Sálek, T | 2 |
Sycová-Milá, Z | 2 |
Obertová, J | 1 |
Hlavatá, Z | 1 |
Mego, M | 1 |
Recková, M | 1 |
Koza, I | 2 |
Bedano, PM | 1 |
Bonnin, J | 1 |
Miyoshi, Y | 1 |
Omori, M | 1 |
Kobayashi, N | 1 |
Masuko, T | 1 |
Watanabe, E | 1 |
Date, I | 1 |
Hara, I | 3 |
Miyake, H | 2 |
Yamada, Y | 2 |
Yamanaka, K | 2 |
Furukawa, J | 1 |
Kumano, M | 1 |
Takenaka, A | 1 |
Fujisawa, M | 1 |
Bauditz, J | 1 |
Lochs, H | 1 |
Ventz, M | 1 |
Agranat, P | 1 |
Jedynak, P | 1 |
Epardeau, B | 1 |
Extra, JM | 1 |
Mignot, L | 1 |
Murphy, BA | 1 |
Mazumdar, M | 5 |
Vlamis, V | 2 |
Nisselbaum, J | 1 |
Head, MD | 1 |
Schwella, N | 2 |
Zingsem, J | 2 |
Strohscheer, I | 2 |
Schwaner, I | 2 |
Oettle, H | 2 |
Serke, S | 1 |
Huhn, D | 3 |
Stieger, W | 1 |
Chou, TC | 1 |
Schwartz, L | 1 |
Bajorin, DF | 4 |
Hutter, H | 1 |
Rodriguez, E | 1 |
Reuter, VE | 1 |
Chaganti, RS | 1 |
Kantoff, PW | 1 |
Demetri, GD | 1 |
Harstrick, A | 3 |
Rüther, U | 1 |
Illiger, HJ | 2 |
Clemm, C | 2 |
Siegert, W | 12 |
Link, H | 1 |
Ostermann, H | 1 |
Lotz, JP | 2 |
André, T | 2 |
Donsimoni, R | 1 |
Firmin, C | 1 |
Bouleuc, C | 2 |
Bonnak, H | 1 |
Merad, Z | 1 |
Esteso, A | 1 |
Gerota, J | 1 |
Izrael, V | 2 |
Fields, KK | 1 |
Elfenbein, GJ | 1 |
Lazarus, HM | 1 |
Cooper, BW | 1 |
Perkins, JB | 1 |
Creger, RJ | 1 |
Ballester, OF | 1 |
Hiemenz, JH | 1 |
Janssen, WE | 1 |
Zorsky, PE | 1 |
Baurmann, H | 1 |
Zimmermann, R | 1 |
Räth, U | 1 |
Hohnloser, J | 1 |
Berdel, W | 1 |
Devalck, C | 1 |
Tempels, D | 1 |
Ferster, A | 1 |
De Laet, MH | 1 |
Bujan, W | 1 |
Heiman, P | 1 |
Sariban, E | 1 |
Lee, PK | 1 |
Dover, JS | 1 |
Farhat, F | 1 |
Culine, S | 2 |
Théodore, C | 1 |
Békradda, M | 2 |
Terrier-Lacombe, MJ | 1 |
Droz, JP | 4 |
Roth, BJ | 1 |
Blanke, C | 1 |
Margolin, K | 1 |
Doroshow, JH | 1 |
Ahn, C | 1 |
Hamasaki, V | 1 |
Leong, L | 1 |
Morgan, R | 1 |
Raschko, J | 1 |
Shibata, S | 1 |
Somlo, G | 1 |
Tetef, M | 1 |
Kramar, A | 2 |
Mandanas, R | 1 |
Linkesch, W | 1 |
Greinix, A | 1 |
Pico, JL | 1 |
Diehl, A | 1 |
Péne, F | 1 |
Gattegno, B | 1 |
Bazelly, B | 1 |
Houry, S | 1 |
Chapiro, J | 1 |
Selle, F | 1 |
Gligorov, J | 1 |
Balat, O | 1 |
Kudelka, AP | 1 |
Edwards, CL | 1 |
Verschraegen, C | 1 |
Kavanagh, JJ | 1 |
Fels, LM | 1 |
Dunn, T | 1 |
Voigt, W | 1 |
Gaedeke, J | 1 |
Stolte, H | 1 |
Lentzen, H | 1 |
Kingreen, D | 2 |
Krause, M | 1 |
Tsumatani, K | 1 |
Ozono, S | 2 |
Momose, H | 1 |
Hirao, Y | 1 |
Okajima, E | 1 |
Kaneko, Y | 1 |
Watanabe, S | 1 |
Samma, S | 1 |
Yamada, K | 1 |
Biron, P | 2 |
Oliver, RT | 2 |
McCaffrey, JA | 1 |
Dunn, TA | 1 |
Grünwald, V | 1 |
Casper, J | 1 |
Brennemann, W | 1 |
Stoffel-Wagner, B | 1 |
Helmers, A | 1 |
Mezger, J | 1 |
Jäger, N | 1 |
Klingmüller, D | 1 |
Weinknecht, S | 1 |
Lenz, K | 1 |
Sawamura, Y | 3 |
Shirato, H | 3 |
Ikeda, J | 3 |
Tada, M | 1 |
Ishii, N | 1 |
Kato, T | 1 |
Abe, H | 1 |
Fujieda, K | 2 |
Kaye, SB | 1 |
Mead, GM | 1 |
Fossa, S | 1 |
Cullen, M | 1 |
deWit, R | 1 |
Bodrogi, I | 1 |
van Groeningen, C | 1 |
Sylvester, R | 2 |
Collette, L | 2 |
Stenning, S | 1 |
De Prijck, L | 2 |
Lallemand, E | 1 |
deMulder, P | 1 |
Pont, J | 1 |
Höltl, W | 1 |
Weissbach, L | 1 |
Crawford, ED | 1 |
Vogelzang, NJ | 1 |
Gonin, R | 1 |
Weathers, T | 1 |
Willenbacher, W | 1 |
Mumm, A | 1 |
Bartsch, HH | 1 |
de Wit, R | 2 |
Stoter, G | 2 |
Sleijfer, DT | 1 |
Neijt, JP | 1 |
ten Bokkel Huinink, WW | 1 |
Gysler, J | 1 |
Schunack, W | 1 |
Jaehde, U | 2 |
Kitamura, K | 1 |
Suzuki, K | 1 |
Miyasaka, K | 2 |
Portas, M | 1 |
Edan, C | 2 |
Chastagner, P | 1 |
Mechinaud-Lacroix, F | 1 |
Kalifa, C | 1 |
Dazzi, C | 1 |
Cariello, A | 1 |
Rosti, G | 2 |
Monti, G | 1 |
Sebastiani, L | 1 |
Argnani, M | 1 |
Nicoletti, P | 1 |
Tienghi, A | 1 |
Leoni, M | 1 |
Fiorentini, G | 1 |
Turci, D | 1 |
Giovanis, P | 1 |
De Giorgi, U | 2 |
Marangolo, M | 2 |
Fléchon, A | 1 |
Philip, I | 1 |
Blay, JY | 1 |
Matsuura, H | 1 |
Sakurai, M | 1 |
Arima, K | 1 |
Germà-Lluch, JR | 1 |
Garcia del Muro, X | 1 |
Tabernero, JM | 1 |
Sánchez, M | 1 |
Aparicio, J | 1 |
Alba, E | 1 |
Barnadas, A | 1 |
Shamash, J | 1 |
Ong, J | 1 |
Raja, M | 1 |
Edmonds, P | 1 |
Gallagher, CJ | 1 |
Ostrowski, MJ | 1 |
LeVay, J | 1 |
Williams, M | 1 |
Schneider, DT | 1 |
Hilgenfeld, E | 1 |
Schwabe, D | 1 |
Behnisch, W | 1 |
Zoubek, A | 1 |
Wessalowski, R | 1 |
Göbel, U | 1 |
Kellner, O | 1 |
Dempke, W | 1 |
Meisner, C | 1 |
Einhorn, L | 1 |
Nichols, C | 1 |
Nomi, M | 1 |
Hara, S | 1 |
Takechi, Y | 1 |
Oka, Y | 1 |
Nakamura, I | 1 |
Gotoh, A | 1 |
Gohji, K | 1 |
Arakawa, S | 1 |
Kamidono, S | 1 |
Soulié, P | 1 |
Garrino, C | 1 |
Bensmaïne, MA | 1 |
Brain, E | 1 |
Di Palma, M | 1 |
Goupil, A | 1 |
Misset, JL | 1 |
Cvitkovic, E | 1 |
Kawakita, M | 1 |
Matsuda, T | 1 |
Terachi, T | 2 |
Yoshida, O | 2 |
Nakagawa, S | 1 |
Miki, T | 1 |
Akaza, H | 1 |
Okano, T | 1 |
Sonoda, Y | 1 |
Naito, K | 1 |
Naito, S | 1 |
Nishiyama, T | 1 |
Nonomura, N | 1 |
Hoshi, S | 1 |
Macapinlac, HA | 1 |
Bains, M | 2 |
Reich, L | 1 |
Flombaum, C | 1 |
Mariani, T | 2 |
Tong, WP | 1 |
Yoshida, T | 1 |
Kitsukawa, S | 1 |
Kin, T | 1 |
Maeda, Y | 1 |
Tscherry, G | 1 |
Jacky, E | 1 |
Jost, LM | 1 |
Stahel, RA | 1 |
Fuchsberger, P | 1 |
Lakota, J | 1 |
Drahokoupilová, M | 1 |
Baláz, M | 1 |
Hanna, A | 1 |
Heresbach, N | 1 |
Guegan, Y | 1 |
Lassmann, J | 1 |
Wille, A | 1 |
Wiechen, K | 1 |
Taupitz, M | 1 |
Loening, SA | 1 |
Papiani, G | 1 |
Aoyama, H | 1 |
Kloft, C | 1 |
16 reviews available for ifosfamide and Germinoma
Article | Year |
---|---|
Ifosfamide in germ cell tumors.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials a | 2003 |
Ifosfamide in pediatric solid tumors.
Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Cyclophosphamide; Germinoma; Humans; Ifosf | 2003 |
Vascular neurotoxicity following chemotherapy with cisplatin, ifosfamide, and etoposide.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Corpus Callosum; Etoposide; Germin | 2004 |
[The result of VIP chemotherapy as an induction therapy in 6 patients with non-seminomatous extragonadal germ cell tumor].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Germinoma; Humans; Ifos | 2004 |
Salvage, dose intense and high-dose chemotherapy for the treatment of poor prognosis or recurrent germ cell tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease-Free Survival; Drug Administr | 2005 |
Paclitaxel in germ cell cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase | 1995 |
The role of ifosfamide in germ cell tumors and small cell lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Topic; Ger | 1995 |
The role of granulocyte-macrophage colony-stimulating factor in the treatment of germ cell tumors. German Testicular Cancer Study Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Chemotherapy, Adjuvant; Cis | 1994 |
Ifosfamide in the treatment of germ cell tumors.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo | 1996 |
The role of ifosfamide in the treatment of testicular and urothelial malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Clinical Trials as Top | 1996 |
Remission of recurrent mixed germ cell tumor of the ovary after treatment with vincristine, carboplatin, fluorouracil, and ifosfamide: a case report and review of the literature.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; An | 1996 |
High-dose chemotherapy in germ-cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cyclophosphamide; Germinoma; | 1996 |
Future trials in germ cell malignancy (GCM) of the testis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineopl | 1997 |
Salvage chemotherapy in relapsed germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Germinoma; Humans; Ifosfamide; | 2001 |
[Treatment of metastatic testicular carcinoma according to prognosis; new development].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Dose-Response Relationship, Dr | 2001 |
The status of high-dose chemotherapy with hematopoietic stem cell transplantation in germ cell tumor patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin; Clinical T | 2002 |
37 trials available for ifosfamide and Germinoma
Article | Year |
---|---|
Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Follow-Up St | 2003 |
First-line sequential high-dose VIP chemotherapy with autologous transplantation for patients with primary mediastinal nonseminomatous germ cell tumours: a prospective trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease | 2003 |
Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer S
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Ther | 2003 |
Combination of paclitaxel, ifosfamide, and cisplatin is an effective second-line therapy for patients with relapsed testicular germ cell tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Confidence Intervals; Dose-Respons | 2005 |
Paclitaxel plus ifosfamide and cisplatin in second-line treatment of germ cell tumors: a phase II study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Germinoma; Humans; Ifosfamide; Mal | 2005 |
Serum tumor marker half-life during chemotherapy in patients with germ cell tumors.
Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chorionic Gon | 1994 |
Hematopoietic rescue after high-dose chemotherapy using autologous peripheral-blood progenitor cells or bone marrow: a randomized comparison.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carb | 1995 |
Recombinant human granulocyte-macrophage colony-stimulating factor as an adjunct to conventional-dose ifosfamide-based chemotherapy for patients with advanced or relapsed germ cell tumors: a randomized trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Germinoma; | 1995 |
High dose chemotherapy with ifosfamide, carboplatin, and etoposide combined with autologous bone marrow transplantation for the treatment of poor-prognosis germ cell tumors and metastatic trophoblastic disease in adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carb | 1995 |
Maximum-tolerated doses of ifosfamide, carboplatin, and etoposide given over 6 days followed by autologous stem-cell rescue: toxicity profile.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neopl | 1995 |
High-dose treatment with carboplatin, etoposide, and ifosfamide followed by autologous stem-cell transplantation in relapsed or refractory germ cell cancer: a phase I/II study. The German Testicular Cancer Cooperative Study Group.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Etopo | 1994 |
A phase I/II study of a stepwise dose-escalated regimen of cisplatin, etoposide and ifosfamide plus granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with advanced germ cell tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Germinoma; Granulocyte-Macroph | 1993 |
Cisplatin and ifosfamide with either vinblastine or etoposide as salvage therapy for refractory or relapsing germ cell tumor patients: the Institut Gustave Roussy experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; | 1996 |
A phase II trial of VP-16, ifosfamide, cisplatin, vinblastine, and bleomycin in advanced germ-cell tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Germinoma; H | 1996 |
Early utilization of high-dose chemotherapy in germ cell tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Protocols; Etoposide; Germinom | 1996 |
High-dose chemotherapy for germ cell tumors (GCT): Memorial Sloan Kettering Cancer Center.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carboplatin; Cisplatin; | 1996 |
The ICE regimen (ifosfamide, carboplatin, etoposide) for the treatment of germ-cell tumors and metastatic trophoblastic disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Th | 1996 |
Long-term survival of patients with recurrent or refractory germ cell tumors after high dose chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease-Free Survival; Etoposide | 1997 |
[Clinical study of testicular cancer].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combi | 1996 |
Gonadal function of patients treated with cisplatin based chemotherapy for germ cell cancer.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Cross-Secti | 1997 |
Paclitaxel in salvage therapy for germ cell tumors.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineo | 1997 |
Nephrotoxicity after high-dose carboplatin, etoposide and ifosfamide in germ-cell tumors: incidence and implications for hematologic recovery and clinical outcome.
Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bo | 1997 |
Intensive induction-sequential chemotherapy with BOP/VIP-B compared with treatment with BEP/EP for poor-prognosis metastatic nonseminomatous germ cell tumor: a Randomized Medical Research Council/European Organization for Research and Treatment of Cancer
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disea | 1998 |
Randomized comparison of cisplatin and etoposide and either bleomycin or ifosfamide in treatment of advanced disseminated germ cell tumors: an Eastern Cooperative Oncology Group, Southwest Oncology Group, and Cancer and Leukemia Group B Study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Germinoma; H | 1998 |
Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Disease-Free Sur | 1998 |
Four cycles of BEP vs four cycles of VIP in patients with intermediate-prognosis metastatic testicular non-seminoma: a randomized study of the EORTC Genitourinary Tract Cancer Cooperative Group. European Organization for Research and Treatment of Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disease-Free Survival; Etoposi | 1998 |
High-dose chemotherapy for salvage treatment of germ cell tumors: Charité, Virchow Klinikum, Berlin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Combined Modality Therapy; D | 1998 |
Combined treatment modality for intracranial germinomas: results of a multicentre SFOP experience. Société Française d'Oncologie Pédiatrique.
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Child; Child, Preschool; Cho | 1999 |
BOMP/EPI intensive alternating chemotherapy for IGCCC poor-prognosis germ-cell tumors: the Spanish Germ-Cell Cancer Group experience (GG)
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplasti | 1999 |
Clinical outcome of high-dose chemotherapy combined with peripheral blood stem cell transplantation for male germ cell tumors.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carboplatin; Combined Modal | 1999 |
Antitumoral activity of oxaliplatin/cisplatin-based combination therapy in cisplatin-refractory germ cell cancer patients.
Topics: Adolescent; Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Ch | 1999 |
[High-dose chemotherapy with peripheral blood stem cell autotransplantation for patients with poor-risk testicular germ cell tumors--pilot study of the Japan Blood Cell Transplantation Study Group].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Car | 1999 |
Sequential dose-intensive paclitaxel, ifosfamide, carboplatin, and etoposide salvage therapy for germ cell tumor patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Dr | 2000 |
Paclitaxel, ifosfamide, and cisplatin second-line therapy for patients with relapsed testicular germ cell cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Germ | 2000 |
Risk-adapted chemotherapy of germ cell tumors with carboplatin, etoposide and bleomycin for low-risk and cisplatin, etoposide and ifosfamide for high-risk patients. A single-center study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 2000 |
Sequential intermediate high-dose therapy with etoposide, ifosfamide and cisplatin for patients with germ cell tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Ther | 2000 |
Toxicity of high-dose carboplatin: ultrafiltered and not total plasma pharmacokinetics is of clinical relevance.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined M | 2002 |
43 other studies available for ifosfamide and Germinoma
Article | Year |
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SIOP CNS GCT 96: final report of outcome of a prospective, multinational nonrandomized trial for children and adults with intracranial germinoma, comparing craniospinal irradiation alone with chemotherapy followed by focal primary site irradiation for pat
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Che | 2013 |
Oncological outcomes of metastatic testicular cancers under centralized management through regional medical network.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disease Man | 2013 |
Clinical interpretation of residual uptake in 11C-methionine positron emission tomography after treatment of basal ganglia germ cell tumors: report of 3 cases.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Carbon Radioisotopes; Chi | 2015 |
Efficacy of Ifosfamide-Cisplatin-Etoposide (ICE) Chemotherapy for a CNS Germinoma in a Child With Down Syndrome.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Cisplatin; Cranial Irradi | 2017 |
SenseCam as a rehabilitation tool in a child with anterograde amnesia.
Topics: Adolescent; Amnesia, Anterograde; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chro | 2011 |
Pattern of relapse and outcome of non-metastatic germinoma patients treated with chemotherapy and limited field radiation: the SFOP experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Case-Control Studies; | 2010 |
Poor-risk testicular cancer and high-dose chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Etoposide; Ger | 2003 |
[Report of two cases with germinoma treated by individual adjuvant chemotherapy based on the mRNA expression of drug-resistance gene].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Ad | 2004 |
[Refractory germ cell cancer of testis treated by salvage high-dose chemotherapy: report of three cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 2004 |
Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Etopo | 2005 |
Metachronous intracranial germinoma in a patient with a previous primary mediastinal seminoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Cisplatin; Combin | 2006 |
[A case of pineal pure germinoma metastasized to the lumbosacral extradural space 8 years after initial therapy. Case report and review of literature].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Cranial | 2006 |
Feasibility and usefulness of high-dose chemotherapy (high-dose ifosfamide, carboplatin and etoposide) combined with peripheral blood stem cell transplantation for male germ cell tumor: a single-institute experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 2006 |
[Long-term follow-up of patients with suprasellar germinomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin | 2007 |
[Cerebral germ cell tumors in adults. A retrospective study of 19 cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Carbo | 1995 |
Serum tumor marker decline is an early predictor of treatment outcome in germ cell tumor patients treated with cisplatin and ifosfamide salvage chemotherapy.
Topics: alpha-Fetoproteins; Biomarkers, Tumor; Chorionic Gonadotropin; Cisplatin; Drug Therapy, Combination; | 1994 |
Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Carcinoma | 1995 |
Long-term disease-free survival in a child with refractory metastatic malignant germ cell tumor treated by high-dose chemotherapy with autologous bone marrow rescues.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Bone Neoplasms; Cisplat | 1994 |
Recurrent exacerbation of acne by granulocyte colony-stimulating factor administration.
Topics: Acne Vulgaris; Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic | 1996 |
Treatment of germ cell cancer with two cycles of high-dose ifosfamide, carboplatin, and etoposide with autologous stem-cell support.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Etopo | 1996 |
High-dose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials, Phase I as Topic; Clin | 1996 |
High-dose chemotherapy and ASCR of patients with relapsed or refractory germ cell tumors: long-term follow-up.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Etoposide; G | 1996 |
Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cisplatin; Disease Models, A | 1996 |
Ifosfamide- and cisplatin-containing chemotherapy as first-line salvage therapy in germ cell tumors: response and survival.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 1997 |
Pre-clinical activity of taxol in non-seminomatous germ cell tumor cell lines and nude mouse xenografts.
Topics: Animals; Cisplatin; Embryonal Carcinoma Stem Cells; Germinoma; Humans; Ifosfamide; In Vitro Techniqu | 1997 |
Induction chemotherapy followed by reduced-volume radiation therapy for newly diagnosed central nervous system germinoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Ad | 1998 |
[High-dose chemotherapy and reinfusion of hematopoietic stem cells in advanced germ cells tumors with poor prognosis--the position in 1996].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Cyclophospha | 1997 |
Late pulmonary toxicity of bleomycin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; E | 1998 |
Monitoring of chemotherapy-induced proteinuria using capillary zone electrophoresis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Buffers; Calibration; Carboplatin; Electropho | 1999 |
Preirradiation evaluation and technical assessment of involved-field radiotherapy using computed tomographic (CT) simulation and neoadjuvant chemotherapy for intracranial germinoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Ad | 1999 |
Peripheral blood progenitor cell (PBPC) mobilization in heavily pretreated patients with germ cell tumors: a report of 34 cases.
Topics: Adolescent; Adult; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combin | 1999 |
[High dose chemotherapy with autologous stem cell support in the treatment of germ cell tumors: experience of the centre Léon-Bérard between 1982 and 1996].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin | 1999 |
[High-dose chemotherapy followed by peripheral blood stem cell transplantation in advanced extragonadal germ cell tumor--a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therapy; Drug | 1999 |
Sixty percent salvage rate for germ-cell tumours using sequential m-BOP, surgery and ifosfamide-based chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disease Pro | 1999 |
Acute myelogenous leukemia after treatment for malignant germ cell tumors in children.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Cisp | 1999 |
[Glucose infusions--a possible effective therapeutic option in ifosfamide-induced encephalopathy].
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Germinoma; | 1999 |
First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: A multivariate and matched-pair analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Controlled Clinical Trials as | 1999 |
[Treatment of advanced testicular cancer and toxicity of chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Etoposide; Germinoma; Humans; | 1999 |
[Treatment results of VIP (etoposide, ifosfamide and cisplatin) chemotherapy as a first-line therapy in metastatic germ cell tumors].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Germinoma; Humans; Ifos | 2000 |
[Expanding mature pineal teratoma syndrome. Case report].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cerebrospinal Fluid S | 2000 |
Diagnostic difficulties before definitive treatment of an extragonadal retroperitoneal germ cell tumor.
Topics: alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Chemo | 2001 |
Induction chemotherapy followed by low-dose involved-field radiotherapy for intracranial germ cell tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Chorionic | 2002 |
Chemotherapy in patients with metastatic or relapsed germ-cell tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Clinical Trials as Topic; Etop | 2001 |