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ifosfamide and Encephalopathy, Toxic

ifosfamide has been researched along with Encephalopathy, Toxic in 50 studies

Research Excerpts

ExcerptRelevanceReference
"Following the 20th week of ifosfamide treatment, the patient's follow-up with the diagnosis of osteosarcoma developed neurological findings."8.02Ifosfamide induced encephalopathy in a child with osteosarcoma. ( Atay, AA; Demir, ÜF; Malbora, B; Sarbay, H; Yılmaz, G, 2021)
"Ifosfamide combined with other antineoplastic agents has been effective in the treatment of osteosarcoma, although adverse effects are reported in the increasing use of ifosfamide."7.80Effects of blood purification therapy on a patient with ifosfamide-induced neurotoxicity and acute kidney injury. ( Enokida, H; Hayami, H; Komiya, S; Nagano, S; Nakagawa, M; Nishimura, H; Yokouchi, M, 2014)
"We retrospectively examined the incidence, severity, and risk factors of ifosfamide encephalopathy in 61 Japanese patients with bone and soft tissue sarcomas at our institution."7.76Ifosfamide encephalopathy associated with chemotherapy for musculoskeletal sarcomas: incidence, severity, and risk factors. ( Kikuchi, S; Konno, S; Tajino, T; Takeda, A; Yamada, H, 2010)
"To report two cases of recurrent uterine sarcoma that developed ifosfamide-induced encephalopathy (IIE) with successful management."7.76Ifosfamide-induced encephalopathy in patients with uterine sarcoma. ( Chang, FW; Liu, YL; Tsai, SH; Yu, MH, 2010)
"Ifosfamide has been shown to be associated with encephalopathy in 10-40% of patients."5.43Severe post-treatment leukopenia associated with the development of encephalopathy following ifosfamide infusion. ( Isola, LM; Kim, SS; Oh, WK, 2016)
"Generalized myoclonus was most common, occurring in four patients while postural tremor was documented in the other three."5.37Ifosfamide associated myoclonus-encephalopathy syndrome. ( Josephs, KA; Rabinstein, AA; Savica, R, 2011)
"Ifosfamide is relatively well tolerated but it can be associated occasionally with life-threatening complications such as arrhythmias and heart failure, severe encephalopathy and hemorrhagic cystitis."4.82Side effects of ifosfamide. ( Klastersky, J, 2003)
"Following the 20th week of ifosfamide treatment, the patient's follow-up with the diagnosis of osteosarcoma developed neurological findings."4.02Ifosfamide induced encephalopathy in a child with osteosarcoma. ( Atay, AA; Demir, ÜF; Malbora, B; Sarbay, H; Yılmaz, G, 2021)
"To determine whether thiamine prophylaxis decreases the incidence of ifosfamide-induced encephalopathy in patients receiving ifosfamide for the treatment of lymphoma."3.96Evaluation of thiamine for the prevention of ifosfamide-induced encephalopathy. ( Ayarza, M; Clark, SM; Hairston, A; Lentz, KL; Liu, B; Morgan, KP; Wind, LS, 2020)
"A retrospective study of sarcoma and lymphoma patients receiving ifosfamide chemotherapy was performed at the participating institutions."3.81An assessment of risk factors associated with ifosfamide-induced encephalopathy in a large academic cancer center. ( Butrynski, J; Cirrone, F; Feng, Y; Fisher, DC; Harris, C; McDonnell, AM; Neuberg, D; Szabatura, AH; Voit, D, 2015)
"Ifosfamide combined with other antineoplastic agents has been effective in the treatment of osteosarcoma, although adverse effects are reported in the increasing use of ifosfamide."3.80Effects of blood purification therapy on a patient with ifosfamide-induced neurotoxicity and acute kidney injury. ( Enokida, H; Hayami, H; Komiya, S; Nagano, S; Nakagawa, M; Nishimura, H; Yokouchi, M, 2014)
"We retrospectively examined the incidence, severity, and risk factors of ifosfamide encephalopathy in 61 Japanese patients with bone and soft tissue sarcomas at our institution."3.76Ifosfamide encephalopathy associated with chemotherapy for musculoskeletal sarcomas: incidence, severity, and risk factors. ( Kikuchi, S; Konno, S; Tajino, T; Takeda, A; Yamada, H, 2010)
"To report two cases of recurrent uterine sarcoma that developed ifosfamide-induced encephalopathy (IIE) with successful management."3.76Ifosfamide-induced encephalopathy in patients with uterine sarcoma. ( Chang, FW; Liu, YL; Tsai, SH; Yu, MH, 2010)
"A retrospective study of inpatients with sarcoma who received a two or four-day regimen of MAI (mesna, doxorubicin, and ifosfamide) between January 1, 2004 and December 31, 2006 was conducted."3.74Characterization of the occurrence of ifosfamide-induced neurotoxicity with concomitant aprepitant. ( Hatfield Seung, A; Howell, JE; Nesbit, SA; Szabatura, AH, 2008)
"Ifosfamide is an alkylating agent used in the treatment of germ-cell tumors, sarcomas and lymphomas."3.73[Ifosfamide induced encephalopathy: 15 observations]. ( Behar, C; Dufour, C; Grill, J; Hartmann, O; Motte, J; Munzer, M; Oberlin, O; Paci, A; Sabouraud, P, 2006)
" During the initial therapy, an ifosfamide-induced encephalopathy occurred as status epilepticus."3.72Prophylactic treatment of known ifosfamide-induced encephalopathy for chemotherapy with high-dose ifosfamide? ( Bellos, F; Egerer, G; Harter, C; Ho, AD; Kasper, B; Krasniqi, F; Meissner, J, 2004)
" Aprepitant is administered as an anti-emetic agent in chemotherapy and regarding the inhibitory effect on CYP3A4, aprepitant can increase the risk of ifosfamide adverse effects."2.82Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review. ( Mohammadpour, AH; Rahimi, H; Sadeghi, M; Samadi, S; Vazirian, F, 2022)
"Prolonged encephalopathy and MB therapy has not been described in the literature as lasting longer than 30 days following treatment."2.82A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature. ( Campino, GA; Chain, G; Kalia, M; Kestenbaum, K; Pappas, L; Sechser-Perl, A; Zaghloul, N, 2022)
"Ifosfamide is a chemotherapy agent commonly used in the treatment of several solid tumors and hematologic malignancies."2.44Ifosfamide neuropsychiatric toxicity in patients with cancer. ( Alici-Evcimen, Y; Breitbart, WS, 2007)
"Ifosfamide is an alkylating agent with well-demonstrated efficacy against a large number of malignant diseases."2.42Neurological toxicity of ifosfamide. ( Giometto, B; Nicolao, P, 2003)
" In most clinical pharmacokinetic studies, the phenomenon of autoinduction has been observed, but the mechanism is not completely understood."2.41Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites. ( Beijnen, JH; de Kraker, J; Groen, HJ; Jansen, RL; Keizer, HJ; Kerbusch, T; Schellens, JH; van Putten, JW, 2001)
"Ifosfamide-related encephalopathy commonly results in a distinct pattern of generalized periodic discharges admixed with intermittent background attenuation on EEG."1.51Clinical and EEG Characteristics of Ifosfamide-Related Encephalopathy. ( Chen, X; Gusdon, AM; Malani, R, 2019)
"Ifosfamide has been shown to be associated with encephalopathy in 10-40% of patients."1.43Severe post-treatment leukopenia associated with the development of encephalopathy following ifosfamide infusion. ( Isola, LM; Kim, SS; Oh, WK, 2016)
"Ifosfamide (IFOS) which is a cytotoxic alkylating agent may cause central nervous system toxicity."1.40Effect of alpha lipoic acid on ifosfamide-induced central neurotoxicity in rats. ( Albayrak, A; Bilen, S; Fadillioglu, E; Ginis, Z; Kurt, SN; Ozturk, G, 2014)
"A serious adverse effect that can limit the utility of ifosfamide is neurotoxicity, known as ifosfamide-induced encephalopathy (IIE)."1.37Evaluation of methylene blue, thiamine, and/or albumin in the prevention of ifosfamide-related neurotoxicity. ( Marshall, H; McQuary, A; Richards, A, 2011)
"Generalized myoclonus was most common, occurring in four patients while postural tremor was documented in the other three."1.37Ifosfamide associated myoclonus-encephalopathy syndrome. ( Josephs, KA; Rabinstein, AA; Savica, R, 2011)
"Ifosfamide is an alkylating agent used in the treatment of several neoplasias."1.36Severe ifosfamide-induced neurotoxicity: a case report. ( Breña Atienza, J; Cabello Rodríguez, A; Cháfer Rudilla, M; Merino Alonso, J; Ramos Linares, S; Ríos Rull, P, 2010)
"One of our patient's encephalopathy and abnormal movements may have improved after the administration of methylene blue and thiamine."1.36Ifosfamide-induced encephalopathy and movement disorder. ( Ames, B; Chaffee, S; Kim, J; Lewis, LD; Morse, R, 2010)
" In the previous five cycles of ifosfamide, carboplatin, and etoposide, the patient had no problems with the neurotoxic adverse effects associated with ifosfamide use."1.35Possible contribution of aprepitant to ifosfamide-induced neurotoxicity. ( Jarkowski, A, 2008)
"Ifosfamide is a well known prodrug for cancer treatment with cytochrome P450 metabolism."1.35New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity. ( Bourget, P; Deroussent, A; Martens, T; Mercier, L; Munier, F; Paci, A; Prost, E; Re, M; Royer, J; Storme, T; Vassal, G, 2009)
" The authors' multidimensional analysis model revealed that besides the total ifosfamide dose and co-administration of other toxic drugs, polymorphic locus of GSTP1 gene may be one of the factors determining a higher toxicity of the cytostatic agent."1.33Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children. ( Misiura, K; Zielińska, E; Zubowska, M, 2005)
"Thiamine appears to be a safe and effective treatment for reversing encephalopathy resulting form ifosfamide infusion, without any significant side effects."1.33Role of thiamine in managing ifosfamide-induced encephalopathy. ( Awan, F; Hamadani, M, 2006)
"08) and dosage (median 2."1.32Incidence and severity of ifosfamide-induced encephalopathy. ( Fiegl, M; Ostermann, H; Rieger, C; Schiel, X; Tischer, J, 2004)
"Ifosfamide is an antineoplastic agent that requires hepatic activation to the cytotoxic active metabolite ifosforamide mustard."1.30Suspected ifosfamide-induced neurotoxicity. ( McVay, JI; Wood, AM, 1999)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.00)18.2507
2000's23 (46.00)29.6817
2010's20 (40.00)24.3611
2020's6 (12.00)2.80

Authors

AuthorsStudies
Chain, G1
Kalia, M1
Kestenbaum, K1
Pappas, L1
Sechser-Perl, A1
Campino, GA1
Zaghloul, N1
Vazirian, F1
Samadi, S1
Rahimi, H1
Sadeghi, M1
Mohammadpour, AH1
Sowell, H1
Gatwood, K1
Perciavalle, M1
Kiani, A1
Nik, SH1
Khodadoost, A1
Salimi, A1
Pourahmad, J1
Sarbay, H1
Demir, ÜF1
Yılmaz, G1
Atay, AA1
Malbora, B1
Gusdon, AM1
Malani, R1
Chen, X1
Lentz, KL1
Clark, SM1
Ayarza, M1
Liu, B1
Morgan, KP1
Wind, LS1
Hairston, A1
Ozturk, G2
Ginis, Z2
Kurt, SN2
Albayrak, A2
Bilen, S1
Fadillioglu, E2
Nishimura, H1
Enokida, H1
Nagano, S1
Yokouchi, M1
Hayami, H1
Komiya, S1
Nakagawa, M1
Albayrak, M1
Szabatura, AH2
Cirrone, F1
Harris, C1
McDonnell, AM1
Feng, Y1
Voit, D1
Neuberg, D1
Butrynski, J1
Fisher, DC1
Peddi, PF1
Peddi, S1
Santos, ES1
Morgensztern, D1
Kim, SS1
Isola, LM1
Oh, WK1
Sunela, K1
Bärlund, M1
Howell, JE1
Hatfield Seung, A1
Nesbit, SA1
Storme, T1
Deroussent, A1
Mercier, L1
Prost, E1
Re, M1
Munier, F1
Martens, T1
Bourget, P1
Vassal, G1
Royer, J1
Paci, A2
Jarkowski, A1
Di Cataldo, A1
Astuto, M1
Rizzo, G1
Bertuna, G1
Russo, G1
Incorpora, G1
Lombardi, G1
Zustovich, F1
Nicoletto, MO1
Donach, M1
Pastorelli, D1
Yuen, C1
Ames, B1
Lewis, LD1
Chaffee, S1
Kim, J1
Morse, R1
Ramos Linares, S1
Breña Atienza, J1
Cháfer Rudilla, M1
Ríos Rull, P1
Cabello Rodríguez, A1
Merino Alonso, J1
Bernard, PA1
McCabe, T1
Bayliff, S1
Hayes, D1
Tajino, T1
Kikuchi, S1
Yamada, H1
Takeda, A1
Konno, S1
Janeway, KA1
Grier, HE1
Liu, YL1
Tsai, SH1
Chang, FW1
Yu, MH1
Kettle, JK1
Grauer, D1
Folker, TL1
O'Neal, N1
Henry, DW1
Williams, CB1
Richards, A1
Marshall, H1
McQuary, A1
Imtiaz, S1
Muzaffar, N1
Savica, R1
Rabinstein, AA1
Josephs, KA1
Turner, AR1
Duong, CD1
Good, DJ1
Klastersky, J1
Nicolao, P1
Giometto, B1
Kasper, B1
Harter, C1
Meissner, J1
Bellos, F1
Krasniqi, F1
Ho, AD1
Egerer, G1
Raj, AB1
Bertolone, SJ1
Jaffe, N1
Rieger, C1
Fiegl, M1
Tischer, J1
Ostermann, H1
Schiel, X1
Kerdudo, C1
Orbach, D1
Sarradet, JL1
Doz, F1
Zielińska, E1
Zubowska, M1
Misiura, K1
Dufour, C1
Grill, J1
Sabouraud, P1
Behar, C1
Munzer, M1
Motte, J1
Oberlin, O1
Hartmann, O1
Patel, PN1
Hamadani, M1
Awan, F1
Alici-Evcimen, Y1
Breitbart, WS1
Ajithkumar, T1
Parkinson, C1
Shamshad, F1
Murray, P1
Brunello, A1
Basso, U1
Rossi, E1
Stefani, M1
Ghiotto, C1
Marino, D1
Crivellari, G1
Monfardini, S1
McVay, JI1
Wood, AM1
Kerbusch, T1
de Kraker, J1
Keizer, HJ1
van Putten, JW1
Groen, HJ1
Jansen, RL1
Schellens, JH1
Beijnen, JH1
Stewart, SL1
Nielsen, E1
Brant, J1
Primavera, A1
Audenino, D1
Cocito, L1
Meyer, T1
Ludolph, AC1
Münch, C1

Reviews

12 reviews available for ifosfamide and Encephalopathy, Toxic

ArticleYear
A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature.
    BMC pediatrics, 2022, 02-02, Volume: 22, Issue:1

    Topics: Brain Diseases; Child; Female; Humans; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Sleepine

2022
Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review.
    Cancer chemotherapy and pharmacology, 2022, Volume: 90, Issue:1

    Topics: Aprepitant; Humans; Ifosfamide; Morpholines; Neurotoxicity Syndromes; Randomized Controlled Trials a

2022
Central nervous system toxicities of chemotherapeutic agents.
    Expert review of anticancer therapy, 2014, Volume: 14, Issue:7

    Topics: Antineoplastic Agents; Central Nervous System Diseases; Cisplatin; Cytarabine; Fluorouracil; Humans;

2014
[Treatment and prevention of iphosphamide-induced encephalopathy].
    Duodecim; laaketieteellinen aikakauskirja, 2016, Volume: 132, Issue:4

    Topics: Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Drug Interactions; Enzyme Inhibitors; Hu

2016
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects.
    The Lancet. Oncology, 2010, Volume: 11, Issue:7

    Topics: Antidotes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Doxorubicin; H

2010
Side effects of ifosfamide.
    Oncology, 2003, Volume: 65 Suppl 2

    Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Cystitis; Drug Interactions; Heart; Hemorrhage; H

2003
Neurological toxicity of ifosfamide.
    Oncology, 2003, Volume: 65 Suppl 2

    Topics: Acetaldehyde; Animals; Antineoplastic Agents, Alkylating; Brain; Carbocysteine; Central Nervous Syst

2003
Methylene blue for management of Ifosfamide-induced encephalopathy.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:2

    Topics: Humans; Ifosfamide; MEDLINE; Methylene Blue; Neurotoxicity Syndromes; Time Factors; Treatment Outcom

2006
Ifosfamide neuropsychiatric toxicity in patients with cancer.
    Psycho-oncology, 2007, Volume: 16, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Burkitt Lymphoma; Delusions; Enzyme Inhibitors; Female; Hu

2007
Ifosfamide encephalopathy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Humans; Ifosfamide; Neurotoxicity Syndromes

2007
Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites.
    Clinical pharmacokinetics, 2001, Volume: 40, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Area Under Curve; Cyclophosphamide; Cytochrome P-450 Enz

2001
Chemotherapy-induced neurotoxicity: assessment and interventions for patients at risk.
    The American journal of nursing, 2002, Volume: 102 Suppl 4

    Topics: Antineoplastic Agents; Cisplatin; Cytarabine; Humans; Ifosfamide; Methotrexate; Neoplasms; Neurotoxi

2002

Other Studies

38 other studies available for ifosfamide and Encephalopathy, Toxic

ArticleYear
Incidence and severity of ICANS following CAR-T therapy in patients previously receiving ifosfamide.
    Bone marrow transplantation, 2023, Volume: 58, Issue:2

    Topics: Humans; Ifosfamide; Immunotherapy, Adoptive; Incidence; Neurotoxicity Syndromes; Patients; Receptors

2023
Trifluoperazine an Antipsychotic Drug and Inhibitor of Mitochondrial Permeability Transition Protects Cytarabine and Ifosfamide-Induced Neurotoxicity.
    Drug research, 2020, Volume: 70, Issue:6

    Topics: Animals; Antineoplastic Agents; Brain; Cells, Cultured; Cytarabine; Disease Models, Animal; Humans;

2020
Ifosfamide induced encephalopathy in a child with osteosarcoma.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:5

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Diseases; Female; Humans; Ifosf

2021
Clinical and EEG Characteristics of Ifosfamide-Related Encephalopathy.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2019, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Brain Diseases; Electroencephalography;

2019
Evaluation of thiamine for the prevention of ifosfamide-induced encephalopathy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2020, Volume: 26, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carboplatin; Cohort Studies; Etoposi

2020
Effect of alpha lipoic acid on ifosfamide-induced central neurotoxicity in rats.
    The International journal of neuroscience, 2014, Volume: 124, Issue:2

    Topics: Animals; Antioxidants; Brain; Caspase 3; Catalase; Ifosfamide; Male; Malondialdehyde; Neurons; Neuro

2014
Effects of blood purification therapy on a patient with ifosfamide-induced neurotoxicity and acute kidney injury.
    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2014, Volume: 17, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Female; Hemodiaf

2014
Protective effects of caffeic acid phenethyl ester on ifosfamide-induced central neurotoxicity in rats.
    Toxicology and industrial health, 2016, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Brain; Caffeic Acids; Catalase; Ifosfamide; Immunohistochemistry; Lipid Perox

2016
An assessment of risk factors associated with ifosfamide-induced encephalopathy in a large academic cancer center.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2015, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Brain Diseases; Cancer Care Facilities; Cisplatin; Female; Humans

2015
Severe post-treatment leukopenia associated with the development of encephalopathy following ifosfamide infusion.
    Anti-cancer drugs, 2016, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Female; Humans; Ifosf

2016
Characterization of the occurrence of ifosfamide-induced neurotoxicity with concomitant aprepitant.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:3

    Topics: Antidotes; Antiemetics; Antineoplastic Agents, Alkylating; Aprepitant; Delirium; Female; Humans; Ifo

2008
New ifosfamide analogs designed for lower associated neurotoxicity and nephrotoxicity with modified alkylating kinetics leading to enhanced in vitro anticancer activity.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Biotransformation; Cells, Cultured; Humans; Ifosfamide;

2009
Possible contribution of aprepitant to ifosfamide-induced neurotoxicity.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Dec-01, Volume: 65, Issue:23

    Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Aprepitant; Carboplatin; Dexamet

2008
Neurotoxicity during ifosfamide treatment in children.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:1

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Cyclophosphamide; Female; Hu

2009
Important role of thiamine in preventing ifosfamide-induced encephalopathy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2010, Volume: 16, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Middl

2010
Aprepitant-associated ifosfamide neurotoxicity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2010, Volume: 16, Issue:2

    Topics: Adult; Antidepressive Agents; Antineoplastic Agents, Alkylating; Aprepitant; Case-Control Studies; F

2010
Ifosfamide-induced encephalopathy and movement disorder.
    Pediatric blood & cancer, 2010, Volume: 54, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Bone Neoplasms; Brain Diseases; Child; Female; Humans

2010
Severe ifosfamide-induced neurotoxicity: a case report.
    Pharmacy world & science : PWS, 2010, Volume: 32, Issue:2

    Topics: Adult; Antineoplastic Agents, Alkylating; Hodgkin Disease; Humans; Ifosfamide; Male; Neurotoxicity S

2010
Successful treatment of ifosfamide neurotoxicity with dexmedetomidine.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2010, Volume: 16, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Antidotes; Antineoplastic Agents, Alkylating; Child, Preschool

2010
Ifosfamide encephalopathy associated with chemotherapy for musculoskeletal sarcomas: incidence, severity, and risk factors.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2010, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Cisplatin; Dose-R

2010
Ifosfamide-induced encephalopathy in patients with uterine sarcoma.
    Taiwanese journal of obstetrics & gynecology, 2010, Volume: 49, Issue:1

    Topics: Aged; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Methylene Blue; Middle Aged; Ne

2010
Effectiveness of exogenous albumin administration for the prevention of ifosfamide-induced encephalopathy.
    Pharmacotherapy, 2010, Volume: 30, Issue:8

    Topics: Academic Medical Centers; Adult; Aged; Female; Humans; Hypoalbuminemia; Ifosfamide; Male; Middle Age

2010
Evaluation of methylene blue, thiamine, and/or albumin in the prevention of ifosfamide-related neurotoxicity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Volume: 17, Issue:4

    Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Humans; Ifosfamide; Methylene Blue; Middle Aged;

2011
Ifosfamide neurotoxicty in a young female with a remarkable response to thiamine.
    JPMA. The Journal of the Pakistan Medical Association, 2010, Volume: 60, Issue:10

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Central Ne

2010
Ifosfamide associated myoclonus-encephalopathy syndrome.
    Journal of neurology, 2011, Volume: 258, Issue:9

    Topics: Antineoplastic Agents, Alkylating; Databases, Factual; Dyskinesia, Drug-Induced; Female; Humans; Ifo

2011
Methylene blue for the treatment and prophylaxis of ifosfamide-induced encephalopathy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Male; Methylene Blue; Ne

2003
Prophylactic treatment of known ifosfamide-induced encephalopathy for chemotherapy with high-dose ifosfamide?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemoprevention; Female; Huma

2004
Methylene blue reversal of ifosfamide-related encephalopathy.
    Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Electroencephalography; Enzyme Inhibitors;

2004
Incidence and severity of ifosfamide-induced encephalopathy.
    Anti-cancer drugs, 2004, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Cohort Studies; Dose-Response Relationship, Drug; Fe

2004
Ifosfamide neurotoxicity: an atypical presentation with psychiatric manifestations.
    Pediatric blood & cancer, 2006, Volume: 47, Issue:1

    Topics: Acute Disease; Adolescent; Antineoplastic Agents, Alkylating; Bipolar Disorder; Humans; Ifosfamide;

2006
Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children.
    Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:11

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Brain Neoplasms; Child; Child, Preschool; Cyclophosph

2005
[Ifosfamide induced encephalopathy: 15 observations].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Coma; Enzyme Inhibitors; Fat

2006
Role of thiamine in managing ifosfamide-induced encephalopathy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2006, Volume: 12, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Female; Humans; Ifosfamide; Male; Middle Aged; Neuro

2006
Ifosfamide-related encephalopathy in elderly patients : report of five cases and review of the literature.
    Drugs & aging, 2007, Volume: 24, Issue:11

    Topics: Abdominal Neoplasms; Aged; Antidotes; Antineoplastic Agents, Alkylating; Antineoplastic Combined Che

2007
Suspected ifosfamide-induced neurotoxicity.
    Pharmacotherapy, 1999, Volume: 19, Issue:12

    Topics: Adult; Antineoplastic Agents, Alkylating; Humans; Ifosfamide; Male; Neurotoxicity Syndromes

1999
Postchemotherapy confusion.
    Oncology nursing forum, 2001, Volume: 28, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Female; Humans; Ifosfamide; M

2001
Ifosfamide encephalopathy and nonconvulsive status epilepticus.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2002, Volume: 29, Issue:2

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Diazepam; Electroencephalography; Epileps

2002
Ifosfamide encephalopathy presenting with asterixis.
    Journal of the neurological sciences, 2002, Jul-15, Volume: 199, Issue:1-2

    Topics: Dyskinesia, Drug-Induced; Dyskinesias; Electroencephalography; Humans; Ifosfamide; Magnetic Resonanc

2002