ifosfamide has been researched along with Down Syndrome in 4 studies
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Zhao, Y | 1 |
| Zhang, X | 1 |
| Badie, H | 1 |
| Zhou, Y | 1 |
| Mu, Y | 1 |
| Loo, LS | 1 |
| Cai, L | 1 |
| Thompson, RC | 1 |
| Yang, B | 1 |
| Chen, Y | 1 |
| Johnson, PF | 1 |
| Wu, C | 1 |
| Bu, G | 1 |
| Mobley, WC | 1 |
| Zhang, D | 1 |
| Gage, FH | 1 |
| Ranscht, B | 1 |
| Zhang, YW | 1 |
| Lipton, SA | 1 |
| Hong, W | 1 |
| Xu, H | 1 |
| Nodomi, S | 1 |
| Umeda, K | 1 |
| Ueno, H | 1 |
| Saida, S | 1 |
| Hiramatsu, H | 1 |
| Funaki, T | 1 |
| Arakawa, Y | 1 |
| Mizowaki, T | 1 |
| Adachi, S | 1 |
| Heike, T | 1 |
| Eckrich, MJ | 1 |
| Domm, J | 1 |
| Ho, R | 1 |
| Whitlock, JA | 1 |
| Frangoul, H | 1 |
| Sugimoto, K | 1 |
| Ideguchi, M | 1 |
| Sadahiro, H | 1 |
| Yoshikawa, K | 1 |
| Goto, H | 1 |
| Nomura, S | 1 |
| Fujii, M | 1 |
| Suzuki, M | 1 |
1 review available for ifosfamide and Down Syndrome
| Article | Year |
|---|---|
Yolk sac tumor of the bilateral basal ganglia in a patient with Down syndrome.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Brain Neoplasms; Chemorad | 2013 |
3 other studies available for ifosfamide and Down Syndrome
| Article | Year |
|---|---|
Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; CCAAT-Enhancer-Binding | 2013 |
Efficacy of Ifosfamide-Cisplatin-Etoposide (ICE) Chemotherapy for a CNS Germinoma in a Child With Down Syndrome.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Cisplatin; Cranial Irradi | 2017 |
Autologous stem cell transplant in a patient with Down syndrome and relapsed Hodgkin lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Child; Combined Modality Ther | 2009 |