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ifosfamide and Disease Exacerbation

ifosfamide has been researched along with Disease Exacerbation in 118 studies

Research Excerpts

ExcerptRelevanceReference
"Doxorubicin and ifosfamide (AI) is standard therapy for high-risk soft tissue sarcoma (STS) but often causes severe toxicities resulting in hospitalisation."9.20A randomised, open-label, phase II study of neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients with localised, high-risk, soft tissue sarcoma. ( Baker, LH; Biermann, JS; Chugh, R; Davis, EJ; Feng, M; Jacobson, J; Lucas, DR; Metko, G; Reinke, D; Schuetze, SM; Wong, SL; Zalupski, MM; Zhao, L; Zyczynski, L, 2015)
"Effective targeted treatment is unavailable for most sarcomas and doxorubicin and ifosfamide-which have been used to treat soft-tissue sarcoma for more than 30 years-still have an important role."9.19Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial. ( Alcindor, T; Blay, JY; dei Tos, AP; Fisher, C; Gelderblom, H; Hartmann, JT; Hermans, C; Hogendoorn, PC; Hohenberger, P; Judson, I; Kerst, JM; Krarup-Hansen, A; Litière, S; Marreaud, S; Schöffski, P; Sufliarsky, J; van der Graaf, WT; Verweij, J; Whelan, J, 2014)
"To assess the progression-free survival (PFS) and antitumor response to standard-dose doxorubicin compared with sequential dose-dense doxorubicin and ifosfamide in first-line treatment of advanced soft tissue sarcoma."9.14Efficacy of sequential high-dose doxorubicin and ifosfamide compared with standard-dose doxorubicin in patients with advanced soft tissue sarcoma: an open-label randomized phase II study of the Spanish group for research on sarcomas. ( Andrés, R; Balañá, C; Buesa, JM; Casado, A; Cruz, J; Cubedo, R; de la Cruz, JJ; de Las Peñas, R; Del Muro, XG; Fra, J; Gallego, O; Gómez, MA; López-Pousa, A; Martín, J; Martínez-Trufero, J; Maurel, J; Poveda, A; Rubió, J; Rubio-Viqueira, B; Sevilla, I, 2009)
"Based on the promising results of a Phase I study with a combination of gemcitabine and DTIC performed in advanced soft tissue sarcoma (ASTS) patients, and due to the limited efficacy of second or third line therapies in those patients, we designed a Phase II study to determine the activity of this new regimen."9.12Phase II study with the combination of gemcitabine and DTIC in patients with advanced soft tissue sarcomas. ( Buesa, JM; Del Muro, JG; Escudero, P; Esteban, E; Fra, J; Gión, M; Goitia, A; López-Pousa, A; Losa, R; Maurel, J; Nadal, R; Sierra, M; Uña, E, 2007)
"To evaluate ICE (ifosfamide, carboplatin, etoposide) as second-line chemotherapy in relapsed or primary progressive aggressive lymphoma, in terms of objective response rate (ORR) and peripheral blood stem cell (PBSC) harvest mobilization rate."9.11ICE (ifosfamide, carboplatin, etoposide) as second-line chemotherapy in relapsed or primary progressive aggressive lymphoma--the Nordic Lymphoma Group experience. ( Holte, H; Jerkeman, M; Kvaløy, S; Leppä, S, 2004)
"Our aim was to determine the efficacy of ifosfamide, mesna, and interferon alpha combination therapy in malignant mesothelioma (MM) patients."9.11Ifosfamide, mesna, and interferon-alpha2A combination chemoimmunotherapy in malignant mesothelioma: results of a single center in central anatolia. ( Altinbas, M; Coskun, HS; Ekici, E; Er, O; Eser, B; Gulmez, I; Kaplan, B; Ozesmi, M; Ozkan, M, 2004)
"The combination of Ifosfamide and L-Dauno was found to be a highly active chemotherapy regimen for first-line treatment of soft tissue sarcoma."9.11Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma: results of a phase II study. ( Deckert, PM; Hütter, G; Keilholz, U; Schmittel, A; Siehl, JM; Szelényi, H; Thiel, E, 2005)
"The authors evaluated the efficacy and toxicity of cisplatin, ifosfamide, and doxorubicin with peripheral blood stem cell (PBSC) support in adult patients with osteosarcomas and variants with a poor prognosis."9.11A phase II study of cisplatin, doxorubicin, and ifosfamide with peripheral blood stem cell support in patients with skeletal osteosarcoma and variant bone tumors with a poor prognosis. ( Benjamin, RS; Champlin, R; Donato, M; Lewis, VO; Lin, PP; Papadopolous, N; Patel, SR; Raymond, AK; Seong, CM; Yasko, AW, 2004)
"The aim of this phase II study was to evaluate the efficacy and toxicity of two regimens of ifosfamide in metastatic soft tissue sarcoma patients given as first- and second-line chemotherapy."9.10Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first- and second-line chemotherapy in advanced soft tissue sarcoma patients. ( Dombernowsky, P; Hermans, C; Judson, I; Krzemieniecki, K; Mouridsen, HT; Nielsen, OS; Spooner, D; Svancarova, L; Van Glabbeke, M; van Oosterom, AT; Verweij, J, 2002)
"The addition of ifosfamide and etoposide to a standard regimen does not affect the outcome for patients with metastatic disease, but it significantly improves the outcome for patients with nonmetastatic Ewing's sarcoma, primitive neuroectodermal tumor of bone, or primitive sarcoma of bone."9.10Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. ( Dickman, PS; Donaldson, SS; Fryer, CJ; Gebhardt, MC; Grier, HE; Krailo, MD; Link, MP; Meyers, PA; Miser, JS; Moore, S; Perlman, EJ; Pritchard, DJ; Rausen, AR; Tarbell, NJ; Vietti, TJ, 2003)
"To determine whether a prolonged 12-day continuous infusion allows the administration of high-dose ifosfamide (IFO) with an acceptable toxicity profile when combined with full-dose doxorubicin (Adriamycin; ADM) as first-line chemotherapy in patients with advanced soft tissue sarcomas."9.10Phase I study of twelve-day prolonged infusion of high-dose ifosfamide and doxorubicin as first-line chemotherapy in adult patients with advanced soft tissue sarcomas. ( Boni, C; Catania, C; Comandone, A; Curigliano, G; de Braud, F; De Pas, T; Marrocco, E; Masci, G; Pagani, O; Tucci, A, 2002)
"Forty-six patients were included in a phase II study to evaluate the response rate and toxicity of a combination of ifosfamide and vinorelbine in metastatic breast cancer patients previously treated with one or more regimens of chemotherapy."9.09Phase II study of ifosfamide plus vinorelbine in metastatic breast cancer patients previously treated with combination chemotherapy. ( Albistur, JJ; Barnadas, A; Constenla, M; Estévez, LG; Frau, A; Lizón, J; Lobo, F; Martínez, P; Méndez, M; Provencio, M; Sánchez, MJ, 1999)
"Patients with locally advanced or metastatic soft tissue sarcoma refractory to treatment with anthracyclines and ifosfamide were enrolled into the present phase II study."9.09Docetaxel as rescue medication in anthracycline- and ifosfamide-resistant locally advanced or metastatic soft tissue sarcoma: results of a phase II trial. ( Amann, G; Attems, Y; Brodowicz, T; Fiebiger, WC; Hejna, M; Köstler, WJ; Krainer, M; Tomek, S; Wiltschke, CH; Zielinski, CC, 2001)
"Thirty-six patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of ifosfamide, carboplatin and etoposide (ICE) at tumour progression."9.08Treatment of recurrent malignant supratentorial gliomas with ifosfamide, carboplatin and etoposide: a phase II study. ( Ameri, A; Delattre, JY; Monjour, A; Poisson, M; Ronchin, P; Sahmoud, T; Sanson, M, 1996)
"We sought to (1) evaluate the disease-specific survival at 2 and 5 years of patients with dedifferentiated chondrosarcoma; (2) assess the prognostic variables (both patient- and treatment-related), including the use of chemotherapy with ifosfamide, that relate to survivorship; and (3) assess specific toxicities associated with ifosfamide use."7.80Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma? ( Deavers, M; Harun, N; Kawaguchi, S; Lewis, VO; Lin, PP; Sun, T, 2014)
"Ifosfamide treatment might be a feasible approach, but it necessitates hospitalization."6.69Chemotherapy in the treatment of recurrent glioblastoma multiforme: ifosfamide versus temozolomide. ( Bamberg, M; Becker, G; Belka, C; Classen, J; Hoffmann, W; Kortmann, RD; Paulsen, F; Weinmann, M, 1999)
" Mesna was administered intravenously at a 20% of the ifosfamide dosage before ifosfamide and orally at 40% after 4 and 8 hours from the ifosfamide infusion."6.68Second line chemotherapy with ifosfamide as outpatient treatment for advanced bladder cancer. ( Pensa, F; Pronzato, P; Tani, F; Vaira, F; Vanoli, M; Vigani, A, 1997)
"The effect of immunotherapy with interleukin-18 (IL-18) in combination with preoperative chemotherapy on the postoperative progression of pulmonary metastasis was examined using a spontaneous pulmonary metastasis model of mouse osteosarcoma."5.35Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model. ( Futani, H; Hata, M; Kogoe, N; Nakasho, K; Ohyama, H; Okamura, H; Terada, N; Yamada, N; Yamanegi, K, 2009)
"We examined the clinical significance of neoadjuvant chemotherapy (NACT) in limb salvage treatment of osteosarcoma and its effect on the Glutaminase 1 gene (GLS1) expression."5.27Significance of neoadjuvant chemotherapy (NACT) in limb salvage treatment of osteosarcoma and its effect on GLS1 expression. ( Li, H; Li, X; Sun, XH; Yan, XF; Zhang, SP, 2018)
"Doxorubicin and ifosfamide (AI) is standard therapy for high-risk soft tissue sarcoma (STS) but often causes severe toxicities resulting in hospitalisation."5.20A randomised, open-label, phase II study of neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients with localised, high-risk, soft tissue sarcoma. ( Baker, LH; Biermann, JS; Chugh, R; Davis, EJ; Feng, M; Jacobson, J; Lucas, DR; Metko, G; Reinke, D; Schuetze, SM; Wong, SL; Zalupski, MM; Zhao, L; Zyczynski, L, 2015)
"Based on the randomised Euro-EWING99-R1 trial, vincristine, adriamycin, cyclophosphamide (VAC) may be able to replace vincristine, adriamycin, ifosfamide (VAI) in the treatment of standard-risk Ewing sarcoma."5.20Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: secondary analysis of the Euro-Ewing99-R1 trial. ( Brennan, B; Brichard, B; Craft, A; Dirksen, U; Gaspar, N; Gelderblom, H; Hjorth, L; Judson, I; Juergens, H; Kruseova, J; Kühne, T; Ladenstein, RL; Le Deley, MC; Le Teuff, G; Marec-Berard, P; Paulussen, M; van den Berg, H; Wheatley, K; Whelan, J, 2015)
"Effective targeted treatment is unavailable for most sarcomas and doxorubicin and ifosfamide-which have been used to treat soft-tissue sarcoma for more than 30 years-still have an important role."5.19Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial. ( Alcindor, T; Blay, JY; dei Tos, AP; Fisher, C; Gelderblom, H; Hartmann, JT; Hermans, C; Hogendoorn, PC; Hohenberger, P; Judson, I; Kerst, JM; Krarup-Hansen, A; Litière, S; Marreaud, S; Schöffski, P; Sufliarsky, J; van der Graaf, WT; Verweij, J; Whelan, J, 2014)
"The aim of this phase II study was to investigate the efficacy and toxicity of combined ifosfamide and cisplatin chemotherapy in patients with recurrent epithelial ovarian cancer (EOC)."5.17Phase II study of ifosfamide and cisplatin for the treatment of recurrent ovarian cancer. ( Bae, DS; Choi, CH; Kim, BG; Kim, MK; Kim, TJ; Lee, JW; Lee, YY; Song, T, 2013)
"To assess the progression-free survival (PFS) and antitumor response to standard-dose doxorubicin compared with sequential dose-dense doxorubicin and ifosfamide in first-line treatment of advanced soft tissue sarcoma."5.14Efficacy of sequential high-dose doxorubicin and ifosfamide compared with standard-dose doxorubicin in patients with advanced soft tissue sarcoma: an open-label randomized phase II study of the Spanish group for research on sarcomas. ( Andrés, R; Balañá, C; Buesa, JM; Casado, A; Cruz, J; Cubedo, R; de la Cruz, JJ; de Las Peñas, R; Del Muro, XG; Fra, J; Gallego, O; Gómez, MA; López-Pousa, A; Martín, J; Martínez-Trufero, J; Maurel, J; Poveda, A; Rubió, J; Rubio-Viqueira, B; Sevilla, I, 2009)
"Patients < or = 30 years with Ewing sarcoma, primitive neuroectodermal tumor or primitive sarcoma of bone were randomly assigned to receive chemotherapy with doxorubicin, vincristine, cyclophosphamide, and dactinomycin, (VACA) or with these four drugs alternating with ifosfamide and etoposide (VACA-IE)."5.12Local control in pelvic Ewing sarcoma: analysis from INT-0091--a report from the Children's Oncology Group. ( Bernstein, M; Chen, Z; Donaldson, SS; Fryer, CJ; Gebhardt, MC; Grier, HE; Krailo, M; Laurie, F; Miser, JS; Tarbell, NJ; Yock, TI, 2006)
"Based on the promising results of a Phase I study with a combination of gemcitabine and DTIC performed in advanced soft tissue sarcoma (ASTS) patients, and due to the limited efficacy of second or third line therapies in those patients, we designed a Phase II study to determine the activity of this new regimen."5.12Phase II study with the combination of gemcitabine and DTIC in patients with advanced soft tissue sarcomas. ( Buesa, JM; Del Muro, JG; Escudero, P; Esteban, E; Fra, J; Gión, M; Goitia, A; López-Pousa, A; Losa, R; Maurel, J; Nadal, R; Sierra, M; Uña, E, 2007)
"The combination of Ifosfamide and L-Dauno was found to be a highly active chemotherapy regimen for first-line treatment of soft tissue sarcoma."5.11Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma: results of a phase II study. ( Deckert, PM; Hütter, G; Keilholz, U; Schmittel, A; Siehl, JM; Szelényi, H; Thiel, E, 2005)
"Our aim was to determine the efficacy of ifosfamide, mesna, and interferon alpha combination therapy in malignant mesothelioma (MM) patients."5.11Ifosfamide, mesna, and interferon-alpha2A combination chemoimmunotherapy in malignant mesothelioma: results of a single center in central anatolia. ( Altinbas, M; Coskun, HS; Ekici, E; Er, O; Eser, B; Gulmez, I; Kaplan, B; Ozesmi, M; Ozkan, M, 2004)
"The authors evaluated the efficacy and toxicity of cisplatin, ifosfamide, and doxorubicin with peripheral blood stem cell (PBSC) support in adult patients with osteosarcomas and variants with a poor prognosis."5.11A phase II study of cisplatin, doxorubicin, and ifosfamide with peripheral blood stem cell support in patients with skeletal osteosarcoma and variant bone tumors with a poor prognosis. ( Benjamin, RS; Champlin, R; Donato, M; Lewis, VO; Lin, PP; Papadopolous, N; Patel, SR; Raymond, AK; Seong, CM; Yasko, AW, 2004)
"To evaluate ICE (ifosfamide, carboplatin, etoposide) as second-line chemotherapy in relapsed or primary progressive aggressive lymphoma, in terms of objective response rate (ORR) and peripheral blood stem cell (PBSC) harvest mobilization rate."5.11ICE (ifosfamide, carboplatin, etoposide) as second-line chemotherapy in relapsed or primary progressive aggressive lymphoma--the Nordic Lymphoma Group experience. ( Holte, H; Jerkeman, M; Kvaløy, S; Leppä, S, 2004)
"The aim of this phase II study was to evaluate the efficacy and toxicity of two regimens of ifosfamide in metastatic soft tissue sarcoma patients given as first- and second-line chemotherapy."5.10Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first- and second-line chemotherapy in advanced soft tissue sarcoma patients. ( Dombernowsky, P; Hermans, C; Judson, I; Krzemieniecki, K; Mouridsen, HT; Nielsen, OS; Spooner, D; Svancarova, L; Van Glabbeke, M; van Oosterom, AT; Verweij, J, 2002)
"The addition of ifosfamide and etoposide to a standard regimen does not affect the outcome for patients with metastatic disease, but it significantly improves the outcome for patients with nonmetastatic Ewing's sarcoma, primitive neuroectodermal tumor of bone, or primitive sarcoma of bone."5.10Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. ( Dickman, PS; Donaldson, SS; Fryer, CJ; Gebhardt, MC; Grier, HE; Krailo, MD; Link, MP; Meyers, PA; Miser, JS; Moore, S; Perlman, EJ; Pritchard, DJ; Rausen, AR; Tarbell, NJ; Vietti, TJ, 2003)
"To determine whether a prolonged 12-day continuous infusion allows the administration of high-dose ifosfamide (IFO) with an acceptable toxicity profile when combined with full-dose doxorubicin (Adriamycin; ADM) as first-line chemotherapy in patients with advanced soft tissue sarcomas."5.10Phase I study of twelve-day prolonged infusion of high-dose ifosfamide and doxorubicin as first-line chemotherapy in adult patients with advanced soft tissue sarcomas. ( Boni, C; Catania, C; Comandone, A; Curigliano, G; de Braud, F; De Pas, T; Marrocco, E; Masci, G; Pagani, O; Tucci, A, 2002)
"Forty-six patients were included in a phase II study to evaluate the response rate and toxicity of a combination of ifosfamide and vinorelbine in metastatic breast cancer patients previously treated with one or more regimens of chemotherapy."5.09Phase II study of ifosfamide plus vinorelbine in metastatic breast cancer patients previously treated with combination chemotherapy. ( Albistur, JJ; Barnadas, A; Constenla, M; Estévez, LG; Frau, A; Lizón, J; Lobo, F; Martínez, P; Méndez, M; Provencio, M; Sánchez, MJ, 1999)
"The aim of this study was to examine the strategy, feasibility and outcome of neo-adjuvant chemotherapy, with doxorubicin and ifosfamide, in adult patients with 'high-risk' soft-tissue sarcomas."5.09A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma. ( Azzarelli, A; Bramwell, VH; Buesa, J; Ezzat, A; Gortzak, E; Kirkpatrick, A; Oosterhuis, JW; Santoro, A; van Coevorden, F; van Geel, AN; van Glabbeke, M; Verweij, J, 2001)
"Patients with locally advanced or metastatic soft tissue sarcoma refractory to treatment with anthracyclines and ifosfamide were enrolled into the present phase II study."5.09Docetaxel as rescue medication in anthracycline- and ifosfamide-resistant locally advanced or metastatic soft tissue sarcoma: results of a phase II trial. ( Amann, G; Attems, Y; Brodowicz, T; Fiebiger, WC; Hejna, M; Köstler, WJ; Krainer, M; Tomek, S; Wiltschke, CH; Zielinski, CC, 2001)
"Thirty-six patients previously treated with surgery, radiation therapy and chemotherapy with a nitrosourea for malignant supratentorial gliomas received a combination of ifosfamide, carboplatin and etoposide (ICE) at tumour progression."5.08Treatment of recurrent malignant supratentorial gliomas with ifosfamide, carboplatin and etoposide: a phase II study. ( Ameri, A; Delattre, JY; Monjour, A; Poisson, M; Ronchin, P; Sahmoud, T; Sanson, M, 1996)
"We sought to (1) evaluate the disease-specific survival at 2 and 5 years of patients with dedifferentiated chondrosarcoma; (2) assess the prognostic variables (both patient- and treatment-related), including the use of chemotherapy with ifosfamide, that relate to survivorship; and (3) assess specific toxicities associated with ifosfamide use."3.80Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma? ( Deavers, M; Harun, N; Kawaguchi, S; Lewis, VO; Lin, PP; Sun, T, 2014)
"Disease progression was discovered when the patient got adjuvant epirubicin, ifosfamide, and bevacizumab for 2 cycles."3.01Perianal rhabdomyosarcoma in an adult: A case report and review of the literature. ( Kong, D; Liu, Y; Wang, X; Yang, N, 2023)
"Six patients experienced early disease progression, and four patients died while on treatment."2.73Experience of the use of trabectedin (ET-743, Yondelis) in 21 patients with pre-treated advanced sarcoma from a single centre. ( Daniels, S; McTiernan, A; Roylance, R; Seddon, B; Sykes, K; Whelan, J, 2007)
"Secondary objectives were time to disease progression, response rates, evaluation of toxicity, disease-related symptoms, World Health Organization performance status (PS), and quality of life (QoL)."2.71Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma. ( Anderson, H; Ashcroft, L; Beresford, C; Burt, PA; Clemons, M; Danson, S; Dowd, I; Fairve-Finn, C; Hassan, J; Middleton, MR; O'Byrne, KJ; Ranson, M; Stout, R; Thatcher, N, 2003)
"Ifosfamide was administered by intravenous infusion over 3 h immediately followed by a 30-min infusion of topotecan."2.70Phase I clinical and pharmacokinetic study of combination chemotherapy with topotecan and ifosfamide in patients with progressive or relapsed solid tumors. ( Grübner, U; Höffken, K; Hoffmann, A; Kath, R; Merkel, U; Schneider, CP, 2002)
"Neutropenia was the dose limiting toxicity (G1=6%, G2=11%, G3=10%, G4=7%)."2.70Vinorelbine, ifosfamide and cisplatin as first-line treatment in patients with inoperable non-small cell lung cancer. ( Camps, C; García, R; Maestu, I; Montalar, J; Morales, S; Segura, A; Torregrosa, D; Vadell, C; Yuste, AL, 2001)
"Ifosfamide treatment might be a feasible approach, but it necessitates hospitalization."2.69Chemotherapy in the treatment of recurrent glioblastoma multiforme: ifosfamide versus temozolomide. ( Bamberg, M; Becker, G; Belka, C; Classen, J; Hoffmann, W; Kortmann, RD; Paulsen, F; Weinmann, M, 1999)
" A doubling of the intensity of cyclophosphamide (or ifosfamide equivalent) dosing per cycle between IRS-III and IRS-IV is thought to be a key contributing factor for this improvement."2.69Benefit of intensified therapy for patients with local or regional embryonal rhabdomyosarcoma: results from the Intergroup Rhabdomyosarcoma Study IV. ( Anderson, JR; Baker, KS; Breneman, JC; Crist, WM; Grier, HE; Link, MP; Maurer, HM; Qualman, SJ; Wiener, ES, 2000)
"The prognosis of platinum resistant ovarian cancer is very poor and the treatment of choice has not been clearly defined."2.69Ifosfamide plus oral etoposide salvage chemotherapy for platinum-resistant paclitaxel-pretreated ovarian cancer. ( Aravantinos, G; Bafaloukos, D; Dimopoulos, MA; Kiamouris, C; Kosmidis, P; Papadimitriou, C; Papakostas, P; Pavlidis, N; Sikiotis, K; Skarlos, DV, 2000)
"Phlebitis was observed in 15 of 30 patients (50%) who did not have central implantable venous systems."2.68Ifosfamide and vinorelbine as first-line chemotherapy for advanced non-small cell lung carcinoma. ( Amato, S; Barbieri, M; Cuevas, M; Dominguez, M; Lacava, J; Langhi, M; Leone, B; Machiavelli, M; Ortiz, E; Perez, J; Rodriguez, R; Romero Acuña, J; Romero Acuña, L; Romero, A; Sabatini, C; Salvadori, M; Vallejo, C, 1996)
" Mesna was administered intravenously at a 20% of the ifosfamide dosage before ifosfamide and orally at 40% after 4 and 8 hours from the ifosfamide infusion."2.68Second line chemotherapy with ifosfamide as outpatient treatment for advanced bladder cancer. ( Pensa, F; Pronzato, P; Tani, F; Vaira, F; Vanoli, M; Vigani, A, 1997)
"There were four patients with pineoblastoma, two of whom had a positive familial history."2.44Trilateral retinoblastoma. ( Antoneli, CB; Arias, VE; Chojniak, MM; Novaes, PE; Ribeiro, Kde C; Sakamoto, LH, 2007)
"On multivariate analysis, metastasectomy and objective response or stable disease achieved with first-line chemotherapy were indicators for better overall survival."1.51Retrospective Analysis of Patients with Advanced Liposarcoma in a Tertiary Referral Center. ( Cornillie, J; Debiec-Rychter, M; Hompes, D; Langmans, C; Schöffski, P; Sciot, R; van Cann, T; Vandenbempt, I; Wozniak, A, 2019)
"However, some patients experience early disease progression."1.48Early disease progression in patients with localized natural killer/T-cell lymphoma treated with concurrent chemoradiotherapy. ( Amaki, J; Asano, N; Choi, I; Ejima, Y; Fukuhara, N; Katayama, N; Kim, SJ; Kim, WS; Ko, YH; Kobayashi, Y; Kubota, N; Maeda, T; Miyazaki, K; Oguchi, M; Saito, B; Shimada, K; Shimoda, E; Soejima, T; Suzuki, R; Terui, Y; Tsukamoto, N; Utsumi, T; Yamaguchi, M, 2018)
"From the Danish Testicular Cancer database, we identified all patients who received more than one line of treatment for disseminated disease."1.42Germ Cell Cancer and Multiple Relapses: Toxicity and Survival. ( Agerbaek, M; Bandak, M; Daugaard, G; Gupta, R; Holm, NV; Kier, MG; Lauritsen, J; Mortensen, MS, 2015)
"Extraosseous osteosarcoma is rare, and the most appropriate therapy is unclear because there are few studies regarding its treatment."1.42Should High-grade Extraosseous Osteosarcoma Be Treated With Multimodality Therapy Like Other Soft Tissue Sarcomas? ( Fan, Z; Guadagnolo, BA; Lewis, VO; Lin, PP; Patel, S, 2015)
"Standard treatment of cervical cancer FIGO stage IB1 is a radical hysterectomy with pelvic lymphadenectomy."1.42Neoadjuvant chemotherapy followed by large cone resection as fertility-sparing therapy in stage IB cervical cancer. ( Leunen, K; Moerman, P; Neven, P; Salihi, R; Van Limbergen, E; Vergote, I, 2015)
"Locally advanced cervical cancer (LACC) is one of the leading health problems of the developing countries."1.42Long follow-up of patients with locally advanced cervical cancer treated with concomitant chemobrachyradiotherapy with cisplatin and ifosfamide followed by consolidation chemotherapy. ( Boraska Jelavić, T; Hamm, W; Hrepić, D; Petrić Miše, B; Prskalo, T; Strikic, A; Tomić, K; Tomić, S; Vrdoljak, E, 2015)
"Teratoid Wilms' tumor is considered by some as a variant of Wilms' tumor containing at least 50% heterologous differentiated tissue."1.37Teratoid Wilms' tumor: case report of a rare variant that can mimic aggressive biology during chemotherapy. ( Raveesunthornkiet, M; Ruangtrakool, R; Sanpaki, K; Thorner, PS; Treetipsatit, J, 2011)
"In relapsed germ cell tumors, salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) is a well-established regimen for patients with favorable features such as a primary testicular tumor and prior complete remission (CR) after the initial chemotherapy."1.37Salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) in relapsed or cisplatin-refractory germ cell tumors. ( Kang, WK; Lee, J; Lee, S; Lim, HY; Park, JO; Park, S; Park, SH; Park, YS, 2011)
"The effect of immunotherapy with interleukin-18 (IL-18) in combination with preoperative chemotherapy on the postoperative progression of pulmonary metastasis was examined using a spontaneous pulmonary metastasis model of mouse osteosarcoma."1.35Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model. ( Futani, H; Hata, M; Kogoe, N; Nakasho, K; Ohyama, H; Okamura, H; Terada, N; Yamada, N; Yamanegi, K, 2009)
"Hemangiopericytoma (HPC) is an uncommon primary brain tumor with an almost invariable tendency to recur and metastasize."1.35Sequential salvage chemotherapy for recurrent intracranial hemangiopericytoma. ( Chamberlain, MC; Glantz, MJ, 2008)
"The patient was diagnosed as having Burkitt's lymphoma (BL) with t(8;14) and t(14;18)."1.34[Early relapse of Burkitt's lymphoma with t(8;14) and t(14;18) after rituximab-combined CODOX-M and IVAC therapy]. ( Fujishima, M; Fujishima, N; Hirokawa, M; Inomata, M; Kameoka, Y; Saitoh, H; Saitoh, K; Sawada, K; Takahashi, N; Yamanaka, Y; Yoshioka, T, 2007)
"Suprasellar germinomas are rare intracranial neoplasms, which mainly occur in children and adolescents and manifest with endocrine symptoms and/or compression syndromes."1.34[Long-term follow-up of patients with suprasellar germinomas]. ( Bauditz, J; Lochs, H; Ventz, M, 2007)
" The purpose of the study was to determine the optimal dosage and the maximal tolerated dose (MTD) of a specified schedule of gemcitabine and ifosfamide."1.33Dose-finding study of fixed dose gemcitabine and escalating doses of ifosfamide given on days 1 and 8 in patients with advanced non-small cell lung cancer. ( Aschroft, L; Baka, S; Blackhall, F; Buchholz, E; Lorigan, P; Manegold, C; Nagel, S; Schott-von-Römer, K; Thatcher, N, 2006)
"Spinal chondrosarcoma are extremely rare and slowly growing tumors."1.33[Upper cervical chondrosarcoma]. ( Domínguez, CJ; Joly, C; Martín-Ferrer, S; Rimbau, J, 2005)
"Although rapid disease progression had resolved transiently, after the start of high-dose chemotherapy, re-progression was apparently observed from day 14."1.32Regression of refractory rhabdomyosarcoma after allogeneic stem-cell transplantation. ( Hosoi, H; Iehara, T; Misawa, A; Sawada, T; Sugimoto, T; Tsuchiya, K, 2003)
" Following an uncomplicated pregnancy, a healthy child was born at full term and careful haematological and immunological monitoring has revealed no adverse effects resulting from exposure to rituximab."1.32Safety of rituximab therapy during the first trimester of pregnancy: a case history. ( Elinder, G; Kimby, E; Sverrisdottir, A, 2004)
"A diagnosis of bilateral Wilms tumor was made following percutaneous biopsy of both kidneys; histologic examination confirmed that the tumor was predominantly rhabdomyomatous."1.31Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor. ( Crooke, MJ; Delahunt, B; Lewis, ME; Pringle, KC; Wiltshire, EJ, 2001)

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (15.25)18.2507
2000's65 (55.08)29.6817
2010's34 (28.81)24.3611
2020's1 (0.85)2.80

Authors

AuthorsStudies
Yang, N1
Kong, D1
Wang, X1
Liu, Y1
Sun, WJ1
Zhang, JJ1
An, N1
Shen, M1
Huang, ZX1
Li, X2
Yamaguchi, M2
Suzuki, R1
Kim, SJ2
Ko, YH1
Oguchi, M1
Asano, N1
Miyazaki, K1
Terui, Y1
Kubota, N1
Maeda, T2
Kobayashi, Y1
Amaki, J1
Soejima, T1
Saito, B1
Shimoda, E1
Fukuhara, N1
Tsukamoto, N1
Shimada, K1
Choi, I1
Utsumi, T1
Ejima, Y1
Kim, WS2
Katayama, N1
Elsebaie, MAT1
Amgad, M1
Elkashash, A1
Elgebaly, AS1
Ashal, GGEL1
Shash, E1
Elsayed, Z1
Zhang, SP1
Li, H1
Sun, XH1
Yan, XF1
Kawamoto, K1
Suzuki, T1
Kasami, T1
Kiryu, M1
Sone, H1
Miyoshi, H1
Ohshima, K1
Takizawa, J1
Langmans, C1
Cornillie, J1
van Cann, T1
Wozniak, A1
Hompes, D1
Sciot, R2
Debiec-Rychter, M1
Vandenbempt, I1
Schöffski, P3
Xu, J1
Li, G1
Zhu, SM1
Cai, QL1
Wang, Z1
Yang, X1
Zhang, HT1
Niu, YJ1
Cucchiari, D1
Bertuzzi, A1
Colombo, P1
De Sanctis, R1
Faucher, E1
Fusco, N1
Pellegrinelli, A1
Arosio, P1
Angelini, C1
Song, T1
Kim, MK1
Lee, YY1
Choi, CH1
Kim, TJ1
Lee, JW1
Kim, BG1
Bae, DS1
Kawaguchi, S1
Sun, T1
Lin, PP3
Deavers, M1
Harun, N1
Lewis, VO3
Vakil, K1
Raza, A1
Zakharova, M1
Madlon-Kay, R1
Skubitz, K1
Patel, M1
Judson, I3
Verweij, J4
Gelderblom, H2
Hartmann, JT1
Blay, JY1
Kerst, JM1
Sufliarsky, J1
Whelan, J3
Hohenberger, P1
Krarup-Hansen, A1
Alcindor, T1
Marreaud, S1
Litière, S1
Hermans, C2
Fisher, C1
Hogendoorn, PC1
dei Tos, AP1
van der Graaf, WT1
Sagara, K1
Takayoshi, K1
Kusumoto, E1
Uchino, K1
Matsumura, T1
Kusaba, H1
Momosaki, S1
Ikejiri, K1
Baba, E1
Petrić Miše, B1
Boraska Jelavić, T1
Strikic, A1
Hrepić, D1
Tomić, K1
Hamm, W1
Tomić, S1
Prskalo, T1
Vrdoljak, E1
Hadoux, J1
Rey, A1
Duvillard, P1
Lhommé, C1
Balleyguier, C1
Haie-Meder, C1
Morice, P1
Tazi, Y1
Leary, A1
Larue, C1
Pautier, P1
Scandurra, G1
Scibilia, G1
Banna, GL2
D'Agate, G1
Lipari, H1
Gieri, S1
Scollo, P1
Boni, C2
Pagano, M1
Baldi, L1
Gnoni, R1
Braglia, L1
Savoldi, L1
Zanelli, F1
Salihi, R1
Leunen, K1
Van Limbergen, E1
Moerman, P1
Neven, P1
Vergote, I1
Davis, EJ1
Chugh, R1
Zhao, L1
Lucas, DR1
Biermann, JS1
Zalupski, MM1
Feng, M1
Wong, SL1
Jacobson, J1
Zyczynski, L1
Reinke, D1
Metko, G1
Baker, LH1
Schuetze, SM1
Zwenger, AO1
Grosman, G1
Iturbe, J1
Leone, J1
Vallejo, CT1
Leone, JP1
Verdera, PP1
Pérez, JE1
Leone, BA1
Fan, Z1
Patel, S1
Guadagnolo, BA1
Lauritsen, J1
Kier, MG1
Mortensen, MS1
Bandak, M1
Gupta, R1
Holm, NV1
Agerbaek, M1
Daugaard, G1
van den Berg, H1
Paulussen, M1
Le Teuff, G1
Dirksen, U1
Brennan, B1
Ladenstein, RL1
Marec-Berard, P1
Kruseova, J1
Hjorth, L1
Kühne, T1
Brichard, B1
Wheatley, K1
Craft, A1
Juergens, H1
Gaspar, N1
Le Deley, MC1
Weigel, BJ1
Lyden, E1
Anderson, JR2
Meyer, WH1
Parham, DM1
Rodeberg, DA1
Michalski, JM1
Hawkins, DS1
Arndt, CA1
Yoon, DH1
Jeong, SH1
Shin, DY1
Bae, SH1
Hong, J1
Park, SK1
Yhim, HY1
Yang, DH1
Lee, H1
Kang, HJ1
Lee, MH1
Eom, HS1
Kwak, JY1
Lee, JH1
Suh, C1
Lorch, A1
Beyer, J1
Chamberlain, MC1
Glantz, MJ1
Maurel, J2
López-Pousa, A2
de Las Peñas, R2
Fra, J2
Martín, J1
Cruz, J1
Casado, A1
Poveda, A1
Martínez-Trufero, J1
Balañá, C1
Gómez, MA1
Cubedo, R1
Gallego, O1
Rubio-Viqueira, B1
Rubió, J1
Andrés, R1
Sevilla, I1
de la Cruz, JJ1
Del Muro, XG1
Buesa, JM2
Aoki, T1
Mizutani, T1
Nojima, K1
Takagi, T1
Okumura, R1
Yuba, Y1
Ueba, T1
Takahashi, JA1
Miyatake, S1
Nozaki, K1
Taki, W1
Matsutani, M1
Kato, T1
Tanabe, J1
Kanemoto, M1
Kobayashi, C1
Morita, S1
Karahashi, T1
Lashkari, A1
Chow, WA1
Valdes, F1
Leong, L1
Phan, V1
Twardowski, P1
Kapoor, N1
Molina, A1
Al-Kadhimi, Z1
Frankel, P1
Somlo, G1
Conrad, AL1
Go, RS1
Saba, NF1
Choi, M1
Muller, S1
Shin, HJ1
Tighiouart, M1
Papadimitrakopoulou, VA1
El-Naggar, AK1
Khuri, FR1
Chen, ZG1
Shin, DM1
Yamada, N1
Hata, M1
Ohyama, H1
Yamanegi, K1
Kogoe, N1
Nakasho, K1
Futani, H1
Okamura, H1
Terada, N1
Kasper, B1
Schmitt, T1
Wuchter, P1
Ho, AD1
Egerer, G2
Fischer, L1
Korfel, A1
Pfeiffer, S1
Kiewe, P1
Volk, HD1
Cakiroglu, H1
Widmann, T1
Thiel, E2
Specenier, PM1
Van Den Brande, J1
Schrijvers, D1
Huizing, MT1
Altintas, S1
Dyck, J1
Van Den Weyngaert, D1
Van Laer, C1
Vermorken, JB1
McCulloch, T1
Prayle, A1
Lunn, A1
Watson, AR1
Cereda, S1
Reni, M1
Rognone, A1
Fugazza, C1
Ghidini, M1
Ceraulo, D1
Brioschi, M1
Nicoletti, R1
Villa, E1
Vello Román, A1
Samprón Rodríguez, M1
Pazos Arias, B1
Romero Reinoso, C1
Peteiro Cancelo, A1
Patrij, K1
Reiser, M1
Wätzel, L1
Pels, H1
Kowoll, A1
Herrlinger, U1
Engert, A1
Linnebank, M1
Schackert, G1
Vogt-Schaden, M1
Lamprecht, M1
Batchelor, TT1
Schlegel, U1
Schmidt-Wolf, IG1
Park, S1
Lee, S1
Lee, J1
Park, SH1
Park, JO1
Kang, WK1
Park, YS1
Lim, HY1
Treetipsatit, J1
Raveesunthornkiet, M1
Ruangtrakool, R1
Sanpaki, K1
Thorner, PS1
Sugimoto, K1
Ideguchi, M1
Sadahiro, H1
Yoshikawa, K1
Goto, H1
Nomura, S1
Fujii, M1
Suzuki, M1
Hervonen, P1
Lehtinen, T1
Tammela, TL1
Kellokumpu-Lehtinen, P1
van Oosterom, AT1
Mouridsen, HT1
Nielsen, OS1
Dombernowsky, P1
Krzemieniecki, K1
Svancarova, L1
Spooner, D1
Van Glabbeke, M2
Misawa, A1
Hosoi, H1
Tsuchiya, K1
Iehara, T1
Sawada, T1
Sugimoto, T1
Gebbia, V2
Galetta, D2
Caruso, M1
Verderame, F1
Pezzella, G1
Valdesi, M1
Borsellino, N1
Pandolfo, G1
Durini, E1
Rinaldi, M1
Loizzi, M1
Gebbia, N2
Valenza, R1
Tirrito, ML1
Varvara, F1
Colucci, G2
Grier, HE3
Krailo, MD1
Tarbell, NJ2
Link, MP2
Fryer, CJ2
Pritchard, DJ1
Gebhardt, MC2
Dickman, PS1
Perlman, EJ1
Meyers, PA2
Donaldson, SS2
Moore, S1
Rausen, AR1
Vietti, TJ1
Miser, JS2
Danson, S1
Middleton, MR1
O'Byrne, KJ1
Clemons, M1
Ranson, M1
Hassan, J1
Anderson, H1
Burt, PA1
Fairve-Finn, C1
Stout, R1
Dowd, I1
Ashcroft, L1
Beresford, C1
Thatcher, N3
Alberola, V1
Camps, C2
Provencio, M2
Isla, D1
Rosell, R1
Vadell, C2
Bover, I1
Ruiz-Casado, A1
Azagra, P1
Jiménez, U1
González-Larriba, JL1
Diz, P1
Cardenal, F1
Artal, A1
Carrato, A1
Morales, S2
Sanchez, JJ1
Felip, E1
López-Vivanco, G1
Kolb, EA1
Kushner, BH1
Gorlick, R1
Laverdiere, C1
Healey, JH1
LaQuaglia, MP1
Huvos, AG1
Qin, J1
Vu, HT1
Wexler, L1
Wolden, S1
Briasoulis, E2
Pavlidis, N2
Terret, C1
Bauer, J1
Fiedler, W1
Raoul, JL1
Hess, D1
Selvais, R1
Lacombe, D2
Bachmann, P2
Fumoleau, P2
Davidson, KL1
Devaney, MB1
Tighe, JE1
Rogers, SY1
Dunlop, DJ1
Mackie, MJ1
Thomas, RV1
Johnson, PR1
Giaccone, G2
Smit, EF1
de Jonge, M1
Dansin, E1
Ardizzoni, A1
Douillard, JY1
Spaeth, D1
Baron, B1
Kimby, E1
Sverrisdottir, A1
Elinder, G1
Patel, SR1
Papadopolous, N1
Raymond, AK1
Donato, M1
Seong, CM1
Yasko, AW1
Champlin, R1
Benjamin, RS1
Jerkeman, M1
Leppä, S1
Kvaløy, S1
Holte, H1
Van der Mieren, G1
Willems, S1
Dumez, H1
Van Oosterom, A1
Flameng, W1
Herijgers, P1
Kawaguchi, T1
Kumabe, T1
Watanabe, M1
Tominaga, T1
Altundag, K1
Aksoy, S1
Gullu, I1
Altundag, O1
Ozyar, E1
Yalcin, S1
Cengiz, M1
Akyol, F1
Altinbas, M1
Er, O1
Ozkan, M1
Coskun, HS1
Gulmez, I1
Ekici, E1
Kaplan, B1
Eser, B1
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Isoda, K1
Yamanaka, K1
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Inomata, M1
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Hirokawa, M1
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Aebi, S1
Solenthaler, M1
Betticher, DC1
Papadimitriou, CA1
Sarris, K1
Kalofonos, C1
Gika, D1
Gourgoulis, GM1
Efstathiou, E1
Skarlos, D1
Schneider, CP1
Merkel, U1
Grübner, U1
Kath, R1
Höffken, K1
Hoffmann, A1

Clinical Trials (19)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomised Trial Of Single Agent Doxorubicin Versus Doxorubicin Plus Ifosfamide In The First Line Treatment Of Advanced Or Metastatic Soft Tissue Sarcoma[NCT00061984]Phase 3455 participants (Actual)Interventional2003-04-30Completed
Trabectedin in Soft Tissue Sarcomas. A Retrospective Observational Analysis (TrObs)[NCT02793050]510 participants (Actual)Observational2016-06-15Completed
RNASARC - Molecular Screening Program of Soft Tissue Sarcomas With Complex Genomic Profile to Detect NTRK1/2/3, ROS1 or ALK Gene Fusions.[NCT03375437]376 participants (Actual)Interventional2018-02-15Active, not recruiting
PEI REGIMEN: A THERAPEUTIC OPTION IN SMALL CELL LUNG CANCER? A MONOINSTITUTIONAL EXPERIENCE OF 46 CONSECUTIVE CASES[NCT02324296]46 participants (Actual)Observational1998-12-31Completed
Prospective Study for the Validation of the Genetic Signature 354849 to Predict the Response to Standard Treatment in Patients With Locally Advanced Cervical Cancer[NCT04067882]189 participants (Anticipated)Observational2019-09-30Recruiting
Phase 3, Open Label, Multi-centre, Randomised Controlled International Study in Ewing Sarcoma[NCT00987636]Phase 3907 participants (Actual)Interventional2009-10-01Completed
ERibulin in Advanced Solitary Fibrous Tumor, an ItaliaN Sarcoma Group Phase II Study (ERASING)[NCT03840772]Phase 216 participants (Anticipated)Interventional2019-07-17Recruiting
A Phase II Multicenter Trial of RAD001 in Patients With Metastatic or Recurrent Sarcomas[NCT01830153]Phase 241 participants (Actual)Interventional2010-04-30Completed
Prospective Evaluation of the Prognostic Relevance of PCR Positivity in Blood and Bone Marrow in Non-Metastatic Ewings Sarcoma[NCT00339898]414 participants (Actual)Observational2004-03-12Completed
A Phase 1, Open-Label, Dose Escalation Study to Evaluate Safety, Pharmacokinetics and Pharmacodynamics of Combined Oral C-Met/ALK Inhibitor (PF-02341066) and Pan-Her Inhibitor (PF-0299804) in Patients With Advanced Non-Small Cell Lung Cancer[NCT01441128]Phase 120 participants (Actual)Interventional2011-09-01Terminated
Open Label Phase II Study on Glufosfamide Administered as a 60 Minute Infusion Every 3 Weeks in Advanced Pancreatic Cancer[NCT00005053]Phase 235 participants (Actual)Interventional1999-12-31Completed
Open Label Phase II Study on Glufosfamide Administered as a 60 Minute Infusion Every 3 Weeks in Advanced Non Small Cell Lung Cancer[NCT00005055]Phase 239 participants (Actual)Interventional2000-01-31Completed
(PRO#11307) Phase III Randomized Study of Autologous Stem Cell Transplantation With High-dose Melphalan Versus High-dose Melphalan and Bortezomib in Patients With Multiple Myeloma 65 Year or Older[NCT01453088]Phase 263 participants (Actual)Interventional2010-06-24Terminated (stopped due to Lack of Accrual)
Tandem Autologous Hematopoietic Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma[NCT01241708]Phase 3146 participants (Actual)Interventional2010-04-08Completed
A Phase II Trial of Pemetrexed (Alimta [Registered Trademark]) Combined With Sirolimus (Rapamycin, Rapamune [Registered Trademark]) in Subjects With Relapsed or Refractory NSCLC[NCT00923273]Phase 1/Phase 242 participants (Actual)Interventional2008-02-29Terminated (stopped due to Premature closure - investigator left the National Institutes of Health.)
A Study on the Efficacy and Safety of Anlotinib Combined With Docetaxel in the Treatment of Wild-type Advanced Non-squamous Non Small Cell Lung Cancer Patients With Progress After Immunotherapy Plus Chemotherapy as First-line Treatment[NCT04619537]Phase 242 participants (Anticipated)Interventional2020-10-08Recruiting
Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies[NCT00703625]Phase 126 participants (Actual)Interventional2008-03-08Completed
A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodg[NCT00479167]Phase 21 participants (Actual)Interventional2007-05-31Terminated (stopped due to Lack of accrual and interest in study)
A Phase Ⅱ Randomized Controlled Trial to Compare Gefitinib With Docetaxel as Second-line Therapy for Advanced or Metastatic Non-squamous NSCLC Patients With Wild-type EGFR[NCT01755923]Phase 260 participants (Anticipated)Interventional2012-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Survival Rate

(NCT01453088)
Timeframe: 1 year

InterventionParticipants (Count of Participants)
Auto Transplant High Dose Melphalan27
Auto Transplant High Dose Melphalan+Bortezomib27

Progression Free Survival Rate

Progression free survival of elderly patients with multiple myeloma treated with either high-dose melphalan versus high-dose melphalan and bortezomib at 3 years (NCT01453088)
Timeframe: Participants will be followed post transplant for a minimum of 3 years, and after that may be monitored as part of the study indefinitely

InterventionParticipants (Count of Participants)
Auto Transplant High Dose Melphalan13
Auto Transplant High Dose Melphalan+Bortezomib11

Phase I: Maximum Tolerated Dose (MTD) of Pemetrexed

The phase I component of the study are to determine the safety and tolerability of pemetrexed in human subjects with non small cell lung cancer (NSCLC), and to determine the maximum tolerated dose. (NCT00923273)
Timeframe: 5 weeks

Interventionmg/m^2 (Number)
Treatment Level 1: 3mg Load500
Treatment Level 2: 6mg Load500
Treatment Level 3: 6mg Load500
Treatment Level 4: 10mg Load500
Treatment Level 5: 15mg Load500

Phase I: Maximum Tolerated Dose (MTD) of Sirolimus

The phase I component of the study are to determine the safety and tolerability of sirolimus in human subjects with non small cell lung cancer (NSCLC), and to determine the maximum tolerated dose. (NCT00923273)
Timeframe: 5 weeks

Interventionmg/m^2 (Number)
Treatment Level 1: 3mg Load10
Treatment Level 2: 6mg Load10
Treatment Level 3: 6mg Load10
Treatment Level 4: 10mg Load10
Treatment Level 5: 15mg Load10

Number of Participants With Serious and Non-Serious Adverse Events

Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria for Adverse Events (CTCAE v3.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life-threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT00923273)
Timeframe: Date treatment consent signed to date off study, approximately 45 months

,,,,
InterventionParticipants (Count of Participants)
Subjects from phase I8subjects prior peme & 12 subjects peme naive
Treatment Level 1: 3mg Load40
Treatment Level 2: 6mg Load30
Treatment Level 3: 6mg Load30
Treatment Level 4: 10 mg Load720
Treatment Level 5: 15mg Load50

Phase II: Clinical Response Rate

Clinical response is assessed by the Response Evaluation Criteria in Solid Tumors (RECIST). Complete response (CR) is disappearance of all target lesions. Partial response (PR) at least a 30% decrease in the sum of the longest diameter (LD) of target lesions, taking as reference the baseline sum LD. Stable disease (SD) is neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD, taking as reference the smallest sum LD since the treatment started. Progressive disease (PD) is at least a 20% increase in the sum of the LD of target lesions, taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions. (NCT00923273)
Timeframe: 21 weeks

InterventionParticipants (Count of Participants)
Complete responsePartial responseStable diseaseProgressive diseaseNot evaluable
Treatment Level 4: 10mg Load051327

Reviews

7 reviews available for ifosfamide and Disease Exacerbation

ArticleYear
Perianal rhabdomyosarcoma in an adult: A case report and review of the literature.
    Medicine, 2023, Dec-01, Volume: 102, Issue:48

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Humans; Ifosfami

2023
High-dose chemotherapy as salvage treatment in germ-cell cancer: when, in whom and how.
    World journal of urology, 2017, Volume: 35, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Dose-Response Relati

2017
Contralateral testicular relapse after prophylactic radiation in a patient with primary testicular diffuse large B-cell lymphoma.
    European journal of haematology, 2009, Dec-01, Volume: 83, Issue:6

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2009
Yolk sac tumor of the bilateral basal ganglia in a patient with Down syndrome.
    Brain tumor pathology, 2013, Volume: 30, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Basal Ganglia; Brain Neoplasms; Chemorad

2013
Trilateral retinoblastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Combined Modality Thera

2007
The pharmacologic basis of ifosfamide use in adult patients with advanced soft tissue sarcomas.
    The oncologist, 2007, Volume: 12, Issue:11

    Topics: Adult; Antineoplastic Agents; Clinical Trials as Topic; Disease Progression; Doxorubicin; Drug Thera

2007
Second-line chemotherapy for non-small-cell lung cancer.
    Current oncology reports, 2000, Volume: 2, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung

2000

Trials

60 trials available for ifosfamide and Disease Exacerbation

ArticleYear
Significance of neoadjuvant chemotherapy (NACT) in limb salvage treatment of osteosarcoma and its effect on GLS1 expression.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:19

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms

2018
Phase II study of ifosfamide and cisplatin for the treatment of recurrent ovarian cancer.
    Cancer chemotherapy and pharmacology, 2013, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ovarian Epithelial; Cisplati

2013
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial.
    The Lancet. Oncology, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free

2014
A randomised, open-label, phase II study of neo/adjuvant doxorubicin and ifosfamide versus gemcitabine and docetaxel in patients with localised, high-risk, soft tissue sarcoma.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Deoxycytidine;

2015
Impact of gender on efficacy and acute toxicity of alkylating agent -based chemotherapy in Ewing sarcoma: secondary analysis of the Euro-Ewing99-R1 trial.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:16

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone

2015
Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016, Jan-10, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy;

2016
Phase II trial of concurrent chemoradiotherapy with L-asparaginase and MIDLE chemotherapy for newly diagnosed stage I/II extranodal NK/T-cell lymphoma, nasal type (CISL-1008).
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chemoradiotherapy; Cispla

2016
Efficacy of sequential high-dose doxorubicin and ifosfamide compared with standard-dose doxorubicin in patients with advanced soft tissue sarcoma: an open-label randomized phase II study of the Spanish group for research on sarcomas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Apr-10, Volume: 27, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dise

2009
Phase II study of ifosfamide, carboplatin, and etoposide in patients with a first recurrence of glioblastoma multiforme.
    Journal of neurosurgery, 2010, Volume: 112, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

2010
Tandem high-dose chemotherapy followed by autologous transplantation in patients with locally advanced or metastatic sarcoma.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Combined Modality

2009
Docetaxel, ifosfamide and cisplatin (DIP) in squamous cell carcinoma of the head and neck.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Case-Control

2009
Salvage therapy with mitomycin and ifosfamide in patients with gemcitabine-resistant metastatic pancreatic cancer: a phase II trial.
    Chemotherapy, 2011, Volume: 57, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Disease Progression; Dis

2011
A randomised dose-finding phase II study on ifosfamide in metastatic hormone-refractory prostate cancer (HRPC).
    Journal of experimental & clinical cancer research : CR, 2002, Volume: 21, Issue:2

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Alkylating; Bone Neoplasms; Disease Progression; Dose-R

2002
Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first- and second-line chemotherapy in advanced soft tissue sarcoma patients.
    European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Disease Progression; Dose-Response Relationship, Dru

2002
Gemcitabine and cisplatin versus vinorelbine and cisplatin versus ifosfamide+gemcitabine followed by vinorelbine and cisplatin versus vinorelbine and cisplatin followed by ifosfamide and gemcitabine in stage IIIB-IV non small cell lung carcinoma: a prospe
    Lung cancer (Amsterdam, Netherlands), 2003, Volume: 39, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Large Cell;

2003
Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone.
    The New England journal of medicine, 2003, Feb-20, Volume: 348, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Cyclophosp

2003
Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma.
    Cancer, 2003, Aug-01, Volume: 98, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Carboplatin; C

2003
Cisplatin plus gemcitabine versus a cisplatin-based triplet versus nonplatinum sequential doublets in advanced non-small-cell lung cancer: a Spanish Lung Cancer Group phase III randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat

2003
Long-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-15, Volume: 21, Issue:18

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Pre

2003
Glufosfamide administered using a 1-hour infusion given as first-line treatment for advanced pancreatic cancer. A phase II trial of the EORTC-new drug development group.
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:16

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Disease Progression; Disease-Free Survival; Fema

2003
A pilot study of CODOX-M/IVAC in primary refractory or relapsed high-grade non-Hodgkin's lymphoma. A Scotland and Newcastle Lymphoma Group Study.
    Haematologica, 2003, Volume: 88, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide;

2003
Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer; a phase II trial of the EORTC-New Drug Development Group.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Child; Child, Presch

2004
A phase II study of cisplatin, doxorubicin, and ifosfamide with peripheral blood stem cell support in patients with skeletal osteosarcoma and variant bone tumors with a poor prognosis.
    Cancer, 2004, Jul-01, Volume: 101, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Diseas

2004
ICE (ifosfamide, carboplatin, etoposide) as second-line chemotherapy in relapsed or primary progressive aggressive lymphoma--the Nordic Lymphoma Group experience.
    European journal of haematology, 2004, Volume: 73, Issue:3

    Topics: Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease Pr

2004
Ifosfamide, mesna, and interferon-alpha2A combination chemoimmunotherapy in malignant mesothelioma: results of a single center in central anatolia.
    Medical oncology (Northwood, London, England), 2004, Volume: 21, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Humans; If

2004
Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma: results of a phase II study.
    Cancer, 2005, Aug-01, Volume: 104, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Disease Progression; Drug

2005
Phase II study with the combination of gemcitabine and DTIC in patients with advanced soft tissue sarcomas.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve;

2007
Local control in pelvic Ewing sarcoma: analysis from INT-0091--a report from the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Aug-20, Volume: 24, Issue:24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Chemotherapy, Adjuvant; Child; Child

2006
Induction chemotherapy with the TIP regimen (paclitaxel/ifosfamide/cisplatin) in stage III non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2006, Volume: 54, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Carcinoma, Non-Small-Cell Lung

2006
Is high-dose chemotherapy after primary chemotherapy a therapeutic option for patients with primary mediastinal nonseminomatous germ cell tumor?
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2006, Volume: 12, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Thera

2006
Standard versus dose-intensified chemotherapy with sequential reinfusion of hematopoietic progenitor cells in small cell lung cancer patients with favorable prognosis.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2007, Volume: 2, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Com

2007
Experience of the use of trabectedin (ET-743, Yondelis) in 21 patients with pre-treated advanced sarcoma from a single centre.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Agents, Alkylating; Dioxoles; Disease Progression;

2007
Gemcitabine, ifosfamide and paclitaxel in advanced/metastatic non-small cell lung cancer patients: a phase II study.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycy

2008
Ifosfamide, etoposide, cytarabine, and methotrexate as salvage chemotherapy in relapsed or refractory aggressive non-Hodgkin's lymphoma.
    Cancer, 1996, Jun-01, Volume: 77, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Diseas

1996
A phase II study of cisplatin/ifosfamide in recurrent/metastatic undifferentiated nasopharyngeal carcinoma among young blacks in southern Africa.
    American journal of clinical oncology, 1996, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined

1996
Phase II study of intensive chemotherapy with carboplatin, ifosfamide and etoposide plus recombinant human granulocyte colony-stimulating factor and sequential radiotherapy in locally advanced, unresectable non-small-cell lung cancer.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma,

1996
Standard versus alternating non-cross-resistant chemotherapy in extensive small cell lung cancer: an EORTC Phase III trial.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Carbopl

1996
Ifosfamide and vinorelbine as first-line chemotherapy for advanced non-small cell lung carcinoma.
    American journal of clinical oncology, 1996, Volume: 19, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Co

1996
Treatment of recurrent malignant supratentorial gliomas with ifosfamide, carboplatin and etoposide: a phase II study.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:13

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Disease Progression; Etopo

1996
Second line chemotherapy with ifosfamide as outpatient treatment for advanced bladder cancer.
    American journal of clinical oncology, 1997, Volume: 20, Issue:5

    Topics: Administration, Oral; Aged; Alopecia; Ambulatory Care; Antineoplastic Agents, Alkylating; Bone Marro

1997
Cisplatin and vinorelbine followed by ifosfamide plus epirubicin vs the opposite sequence in advanced unresectable stage III and metastatic stage IV non-small-cell lung cancer: a prospective randomized study of the Southern Italy Oncology Group (GOIM).
    British journal of cancer, 1997, Volume: 76, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat

1997
Intensive induction-sequential chemotherapy with BOP/VIP-B compared with treatment with BEP/EP for poor-prognosis metastatic nonseminomatous germ cell tumor: a Randomized Medical Research Council/European Organization for Research and Treatment of Cancer
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disea

1998
Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.
    Journal of neuro-oncology, 1998, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Che

1998
Second-line chemotherapy with cisplatin-ifosfamide in patients with ovarian cancer previously treated with carboplatin-cyclophosphamide.
    Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cyclophosphamide; Dise

1999
Chemotherapy in the treatment of recurrent glioblastoma multiforme: ifosfamide versus temozolomide.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:7

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbazin

1999
A phase II study of a three-drug combination (cisplatin, ifosfamide and vinorelbine) plus granulocyte-colony stimulating factor in advanced non small cell lung cancer.
    Journal of chemotherapy (Florence, Italy), 1999, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat

1999
Phase II study of ifosfamide plus vinorelbine in metastatic breast cancer patients previously treated with combination chemotherapy.
    Cancer chemotherapy and pharmacology, 1999, Volume: 44 Suppl

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

1999
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Disease Progression; Disease-Free

2000
Benefit of intensified therapy for patients with local or regional embryonal rhabdomyosarcoma: results from the Intergroup Rhabdomyosarcoma Study IV.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclophosphamid

2000
Ifosfamide plus oral etoposide salvage chemotherapy for platinum-resistant paclitaxel-pretreated ovarian cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot

2000
A randomised phase II study on neo-adjuvant chemotherapy for 'high-risk' adult soft-tissue sarcoma.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Com

2001
Vinorelbine, ifosfamide and cisplatin as first-line treatment in patients with inoperable non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2001, Volume: 34, Issue:2

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lun

2001
Docetaxel as rescue medication in anthracycline- and ifosfamide-resistant locally advanced or metastatic soft tissue sarcoma: results of a phase II trial.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:9

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Disease Pro

2001
Intensive salvage therapy with high-dose chemotherapy for patients with advanced Hodgkin's disease in relapse or failure after initial chemotherapy: results of the Groupe d'Etudes des Lymphomes de l'Adulte H89 Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jan-15, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Dis

2002
Phase I study of twelve-day prolonged infusion of high-dose ifosfamide and doxorubicin as first-line chemotherapy in adult patients with advanced soft tissue sarcomas.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Dose-Response Rela

2002
Maintenance daily oral etoposide versus no further therapy following induction chemotherapy with etoposide plus ifosfamide plus cisplatin in extensive small-cell lung cancer: a Hoosier Oncology Group randomized study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small

2002
A Phase II study of paclitaxel by 24-hour infusion and ifosfamide in anthracycline-resistant metastatic breast carcinoma.
    Cancer, 2002, Apr-01, Volume: 94, Issue:7

    Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Pro

2002
Intensive chemotherapy with whole blood stem-cell support and concurrent chest radiotherapy in small cell lung cancer: a phase I/II trial.
    Lung cancer (Amsterdam, Netherlands), 2002, Volume: 36, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Chi

2002
Combination of ifosfamide, paclitaxel, and cisplatin for the treatment of metastatic and recurrent carcinoma of the uterine cervix: a phase II study of the Hellenic Cooperative Oncology Group.
    Gynecologic oncology, 2002, Volume: 85, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Drug Ad

2002
Phase I clinical and pharmacokinetic study of combination chemotherapy with topotecan and ifosfamide in patients with progressive or relapsed solid tumors.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve

2002

Other Studies

51 other studies available for ifosfamide and Disease Exacerbation

ArticleYear
Clinical analysis of 40 multiple myeloma patients with extramedullary plasmacytoma of the head.
    The Journal of international medical research, 2016, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bortezomib; Dexamethasone; Disease Progressio

2016
Early disease progression in patients with localized natural killer/T-cell lymphoma treated with concurrent chemoradiotherapy.
    Cancer science, 2018, Volume: 109, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carbopla

2018
Management of Low and Intermediate Risk Adult Rhabdomyosarcoma: A Pooled Survival Analysis of 553 Patients.
    Scientific reports, 2018, 06-19, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthracyclines; Cyclophosphamide; Disease Progression; F

2018
Safety and effective salvage regimen comprising a novel combination of brentuximab vedotin, L-asparaginase, and dexamethasone for refractory anaplastic large cell lymphoma, anaplastic lymphoma kinase negative.
    Hematological oncology, 2019, Volume: 37, Issue:2

    Topics: Aged; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bren

2019
Retrospective Analysis of Patients with Advanced Liposarcoma in a Tertiary Referral Center.
    Oncology research and treatment, 2019, Volume: 42, Issue:7-8

    Topics: Adult; Aged; Antineoplastic Agents; Disease Progression; Doxorubicin; Female; Humans; Ifosfamide; Li

2019
Neoadjuvant docetaxel, cisplatin and ifosfamide (ITP) combination chemotherapy for treating penile squamous cell carcinoma patients with terminal lymph node metastasis.
    BMC cancer, 2019, Jun-25, Volume: 19, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Di

2019
Juxtaglomerular cell tumor: multicentric synchronous disease associated with paraneoplastic syndrome.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, May-10, Volume: 31, Issue:14

    Topics: Antidiuretic Hormone Receptor Antagonists; Antineoplastic Combined Chemotherapy Protocols; Benzazepi

2013
Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma?
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bone Neoplasms; Cell Dedifferenti

2014
An absolute obstacle: cardiac metastasis of synovial sarcoma.
    The American journal of medicine, 2014, Volume: 127, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Deoxycytidine; Disease Progressi

2014
Favorable control of rapidly progressive retroperitoneal pleomorphic leiomyosarcoma with multimodality therapy: a case report.
    BMC research notes, 2014, Jun-19, Volume: 7

    Topics: Aged; Antineoplastic Agents; Combined Modality Therapy; Disease Progression; Doxorubicin; Female; Ga

2014
Long follow-up of patients with locally advanced cervical cancer treated with concomitant chemobrachyradiotherapy with cisplatin and ifosfamide followed by consolidation chemotherapy.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2015, Volume: 25, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell

2015
Multimodal treatment with doxorubicin, cisplatin, and ifosfamide for the treatment of advanced or metastatic uterine leiomyosarcoma: a unicentric experience.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2015, Volume: 25, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Cisplatin; Combined Modali

2015
Efficacy and tolerability of paclitaxel, ifosfamide, and cisplatin as a neoadjuvant chemotherapy in locally advanced cervical carcinoma.
    Journal of gynecologic oncology, 2015, Volume: 26, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Di

2015
Pei regimen: a therapeutic option in small cell lung cancer? A retrospective monoinstitutional analysis of 46 consecutive cases.
    Journal of translational medicine, 2015, Apr-24, Volume: 13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Etoposide; Fem

2015
Neoadjuvant chemotherapy followed by large cone resection as fertility-sparing therapy in stage IB cervical cancer.
    Gynecologic oncology, 2015, Volume: 139, Issue:3

    Topics: Abortion, Missed; Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin

2015
Expression of ERCC1 and TUBB3 in locally advanced cervical squamous cell cancer and its correlation with different therapeutic regimens.
    The International journal of biological markers, 2015, Jul-22, Volume: 30, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brac

2015
Should High-grade Extraosseous Osteosarcoma Be Treated With Multimodality Therapy Like Other Soft Tissue Sarcomas?
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemotherapy, Adjuvant;

2015
Germ Cell Cancer and Multiple Relapses: Toxicity and Survival.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Oct-01, Volume: 33, Issue:28

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cisplatin; Datab

2015
Sequential salvage chemotherapy for recurrent intracranial hemangiopericytoma.
    Neurosurgery, 2008, Volume: 63, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cisplatin; Cyclophosphamide;

2008
A case of extranodal NK/T-cell lymphoma, nasal type mimicking typical manifestations of adult-onset Still's disease (AOSD) with hemophagocytic syndrome: diagnostic consideration between malignant lymphoma without lymphadenopathy and AOSD.
    Modern rheumatology, 2009, Volume: 19, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Dexamethasone

2009
Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Case-Control

2009
Immunotherapy with interleukin-18 in combination with preoperative chemotherapy with ifosfamide effectively inhibits postoperative progression of pulmonary metastases in a mouse osteosarcoma model.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2009, Volume: 30, Issue:4

    Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Progression; Female; Ifosfamide; Immunotherapy; I

2009
[Positron emission tomography as a tool for early prediction of therapy outcome in soft tissue sarcoma].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:39

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Doxorubicin; Etoposide;

2009
CXCL13 and CXCL12 in central nervous system lymphoma patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Oct-01, Volume: 15, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C

2009
Karyomegalic-like nephropathy, Ewing's sarcoma and ifosfamide therapy.
    Pediatric nephrology (Berlin, Germany), 2011, Volume: 26, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Biopsy; Cell Nucleus Shape; Chronic Disease; Disease

2011
[Nephropathy following administration of angiogenesis inhibitors].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2011, Volume: 31, Issue:2

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2011
Isolated central nervous system relapse of systemic lymphoma (SCNSL): clinical features and outcome of a retrospective analysis.
    German medical science : GMS e-journal, 2011, Volume: 9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclo

2011
Salvage chemotherapy with paclitaxel, ifosfamide, and cisplatin (TIP) in relapsed or cisplatin-refractory germ cell tumors.
    Onkologie, 2011, Volume: 34, Issue:8-9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Disease-Free

2011
Teratoid Wilms' tumor: case report of a rare variant that can mimic aggressive biology during chemotherapy.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dactinomycin; Disease Progression; Doxo

2011
Regression of refractory rhabdomyosarcoma after allogeneic stem-cell transplantation.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cispl

2003
Safety of rituximab therapy during the first trimester of pregnancy: a case history.
    European journal of haematology, 2004, Volume: 72, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplast

2004
Pericardial synovial sarcoma: 14-year survival with multimodality therapy.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:3

    Topics: Adult; Chemotherapy, Adjuvant; Dimethoate; Disease Progression; Doxorubicin; Drug Administration Sch

2004
Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult.
    Acta neurochirurgica, 2004, Volume: 146, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Cisplatin; Combined Mod

2004
Salvage ifosfamide-doxorubicin chemotherapy in patients with recurrent nasopharyngeal carcinoma pretreated with Cisplatin-based chemotherapy.
    Medical oncology (Northwood, London, England), 2004, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agen

2004
Extra nodal NK/T-cell lymphoma nasal type that responded to DeVIC combination chemotherapy.
    The Journal of dermatology, 2005, Volume: 32, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carboplatin; Combined Modality

2005
[Upper cervical chondrosarcoma].
    Neurocirugia (Asturias, Spain), 2005, Volume: 16, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Axis, Cervical Vertebra; Brachytherapy; Cervical Ver

2005
Prognostic factors in pleuro-pulmonary blastoma.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Child; Child, P

2007
False-positive restaging PET scans involving the spleen in two patients with aggressive non-Hodgkin lymphoma.
    Clinical nuclear medicine, 2006, Volume: 31, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2006
Dose-finding study of fixed dose gemcitabine and escalating doses of ifosfamide given on days 1 and 8 in patients with advanced non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2006, Volume: 53, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Ch

2006
Recurrent superior mediastinal primary hemangiopericytoma 23 years after the complete initial excision: a case report.
    Acta medica Okayama, 2006, Volume: 60, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Epirubicin; Fatal Outcome

2006
Late response to radiochemotherapy in pediatric glioblastoma: report on two patients treated according to HIT-GBM protocols.
    Pediatric hematology and oncology, 2006, Volume: 23, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Cisplatin; Combined Mod

2006
Successful treatment of a child with late-onset T-cell post-transplant lymphoproliferative disorder/lymphoma.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antine

2008
Electrolyte abnormalities and progressive renal failure in a cancer patient.
    Kidney international, 2007, Volume: 71, Issue:11

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Biopsy; C

2007
[Early relapse of Burkitt's lymphoma with t(8;14) and t(14;18) after rituximab-combined CODOX-M and IVAC therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemo

2007
[Long-term follow-up of patients with suprasellar germinomas].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin

2007
Peripheral-T-cell lymphoma with hemophagocytic histiocytosis localised to the bone marrow associated with inappropriate secretion of antidiuretic hormone.
    Leukemia & lymphoma, 1995, Volume: 19, Issue:5-6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Cisplatin; Cy

1995
p53 gene mutation in the bone-marrow of a patient with diffuse mixed cell type lymphoma at diagnosis predicting eventual progression to large cell lymphoma.
    Leukemia & lymphoma, 1998, Volume: 29, Issue:3-4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cisplatin; Dexamethasone; Disease Progr

1998
Sixty percent salvage rate for germ-cell tumours using sequential m-BOP, surgery and ifosfamide-based chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1999, Volume: 10, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Disease Pro

1999
A high proliferation rate measured by cyclin A predicts a favourable chemotherapy response in soft tissue sarcoma patients.
    British journal of cancer, 1999, Volume: 81, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Div

1999
[Pigmented villonodular synovitis: apropos of 3 cases].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2001, Volume: 5, Issue:2

    Topics: Adult; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Arthroplasty, Replaceme

2001
Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor.
    American journal of clinical pathology, 2001, Volume: 116, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Creatine Kinase; Dactinomycin; Di

2001