Page last updated: 2024-10-29

ifosfamide and Carcinoma, Bronchial

ifosfamide has been researched along with Carcinoma, Bronchial in 26 studies

Research Excerpts

ExcerptRelevanceReference
"Fifty-three patients with inoperable non-small cell bronchial carcinoma were treated at four-weekly intervals with two cytostatic drugs, doxorubicin (50 mg/m2 on day 1) and ifosfamide (2000 mg/m2 on days 1-3)."7.66[Combined cytostatic chemotherapy of advanced non-small-cell bronchial carcinoma with doxorubicin and ifosfamide]. ( Göbel, D; Matthiessen, W; Stempinski, E; Thalmann, U, 1983)
"Fifty-three patients with inoperable non-small cell bronchial carcinoma were treated at four-weekly intervals with two cytostatic drugs, doxorubicin (50 mg/m2 on day 1) and ifosfamide (2000 mg/m2 on days 1-3)."3.66[Combined cytostatic chemotherapy of advanced non-small-cell bronchial carcinoma with doxorubicin and ifosfamide]. ( Göbel, D; Matthiessen, W; Stempinski, E; Thalmann, U, 1983)
"The early stages of bronchial carcinoma are still a domain of operative treatment."2.68[Neoadjuvant radiochemotherapy in locally advanced non-small cell bronchial carcinoma. Initial results of a prospective multicenter study]. ( Klinke, F; Micke, O; Rübe, C; von Eiff, M; Wagner, W; Willich, N, 1995)
" As compared with the values obtained on day 1, on day 5 the terminal half-life and AUC values determined for IF were reduced by 30% (6."1.29Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy. ( Kurowski, V; Wagner, T, 1993)
" Both schedules resulted in a reduction in the elimination half-life with an increased total and nonrenal clearance of ifosfamide over the 5-day period."1.28Comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma. ( Cerny, T; Lind, MJ; Margison, JM; Thatcher, N; Wilkinson, PM, 1989)
"The most frequent histology was squamous cell carcinoma found in 20 patients."1.27[Chemotherapy with mitomycin C, vindesine and ifosfamide in the treatment of inoperable non-small cell bronchial carcinoma]. ( Gatzemeier, U; Hossfeld, DK; Radenbach, D; Zschaber, R, 1985)
" There was a proportionate increase in the AUC for the 5-g oral dose, indicating 100% bioavailability at all three dose levels."1.27Bioavailability of ifosfamide in patients with bronchial carcinoma. ( Cerny, T; Margison, JM; Thatcher, N; Wilkinson, PM, 1986)
"Oral ifosfamide therapy was determined to be feasible, and further studies are justified to assess the pharmacokinetics of the optimum dosage and scheduling regimens."1.26The bioavailability of oral and intravenous ifosfamide in the treatment of bronchogenic carcinoma. ( McNiel, NO; Morgan, LR, 1981)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199021 (80.77)18.7374
1990's4 (15.38)18.2507
2000's1 (3.85)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boutemy, M1
Mispelaere, D1
Krzisch, C1
Jounieaux, V1
Liesenfeld, A1
Havemann, K2
Gropp, C1
Seifert, W1
Thomas, C1
Drings, P2
Mahnke, HG1
Westerhausen, M1
Wellens, W1
Konrad, RM1
Bryant, BM1
Jarman, M1
Ford, HT1
Smith, IE1
Valdivieso, M4
Cabanillas, F1
Keating, M1
Barkley, HT3
Murphy, WK4
Burgess, MA1
Frazier, H1
Chen, T1
Bodey, GP3
Seeber, S1
Dimitriadis, K1
Schütte, J1
Schmidt, CG1
Matthiessen, W2
Stempinski, E2
Göbel, D2
Thalmann, U2
Benjamin, RS2
Freeman, MB1
Ertel, M1
Smith, TL1
Mountain, CF1
Morgan, LR2
Holdiness, MR1
Gillen, LE1
McNiel, NO1
Wagner, W1
von Eiff, M1
Klinke, F1
Micke, O1
Rübe, C1
Willich, N1
Kurowski, V2
Wagner, T2
Cohen, MH1
Ihde, DC1
Bunn, PA1
Fossieck, BE1
Matthews, MJ1
Shackney, SE1
Johnston-Early, A1
Makuch, R1
Minna, JD1
Holoye, PY1
Glisson, BS1
Lee, JS1
Dhingra, HM2
Umsawasdi, T2
Levy, JK1
Jeffries, D1
Raber, MN1
Hong, WK1
Lind, MJ1
Margison, JM2
Cerny, T2
Thatcher, N2
Wilkinson, PM2
Banks, J1
Anderson, EG1
Smith, AP1
Manke, HG1
Gatzemeier, U1
Hossfeld, DK1
Radenbach, D1
Zschaber, R1
Loehrer, PJ1
Birch, R1
Kramer, BS1
Greco, FA1
Einhorn, LH1
Frankmann, C1
McMurtrey, MJ1
Jeffries, DG1
Welch, SR1
Li, GC1
Brock, N1
Li, JQ1
Guan, ZZ1
He, YJ1
Spitzer, G1
Farha, P1
Dicke, K1
Zander, A1
Vellekoop, L1
Chiuten, D1
Hoefer, H1
Scheef, W1
Titscher, R1
Kokron, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase Ⅱ Randomized Clinical Trial Comparing Vinorelbine-ifosfamide With Gefitinib as Third-line Treatment in Advanced EGFR Gene Mutation Negative Non-small Cell Lung Cancer Patients[NCT01749072]Phase 2120 participants (Anticipated)Interventional2012-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

8 trials available for ifosfamide and Carcinoma, Bronchial

ArticleYear
Prevention of isophosphamide-induced urothelial toxicity with 2-mercaptoethane sulphonate sodium (mesnum) in patients with advanced carcinoma.
    Lancet (London, England), 1980, Sep-27, Volume: 2, Issue:8196

    Topics: Acrolein; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Female; Hematuria; Hu

1980
Role of intravenous hyperalimentation as an adjunct to intensive chemotherapy for small cell bronchogenic carcinoma.
    Cancer treatment reports, 1981, Volume: 65 Suppl 5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bon

1981
[Neoadjuvant radiochemotherapy in locally advanced non-small cell bronchial carcinoma. Initial results of a prospective multicenter study].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1995, Volume: 171, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Brain; Carboplatin; Carcinoma, Bronc

1995
Urinary excretion of ifosfamide, 4-hydroxyifosfamide, 3- and 2-dechloroethylifosfamide, mesna, and dimesna in patients on fractionated intravenous ifosfamide and concomitant mesna therapy.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Carcinoma, Bronchoge

1997
Cyclic alternating combination chemotherapy for small cell bronchogenic carcinoma.
    Cancer treatment reports, 1979, Volume: 63, Issue:2

    Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin

1979
Ifosfamide plus N-acetylcysteine in the treatment of small cell and non-small cell carcinoma of the lung: a Southeastern Cancer Study Group Trial.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Acetylcysteine; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic

1986
High-dose intensification therapy with autologous bone marrow support for limited small-cell bronchogenic carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carcinoma,

1986
[Treatment of bronchogenic cancer and lung metastases of solid tumors with ifosfamid (author's transl)].
    Osterreichische Zeitschrift fur Onkologie. Austrian journal of oncology, 1974, Issue:1

    Topics: Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Female; Humans

1974

Other Studies

18 other studies available for ifosfamide and Carcinoma, Bronchial

ArticleYear
[Evaluation of combined chemotherapy with vinorelbine, ifosfamide and cisplatin in the treatment of metastatic non-small cell bronchial carcinoma].
    Revue des maladies respiratoires, 2005, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcin

2005
[3 multicenter phase II studies of the treatment of small cell bronchogenic carcinoma (incl. AIO studies BI + BII)].
    Onkologie, 1984, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Ca

1984
Combination chemotherapy of small-cell bronchogenic carcinoma with etoposide (VP-16), ifosfamide and vindesine (VPIV), and with adriamycin, cis-platinum and vincristine (APO).
    Cancer treatment reviews, 1982, Volume: 9 Suppl

    Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cisplatin; Doxorubicin; Drug

1982
Effects of intensive induction chemotherapy for extensive-disease small cell bronchogenic carcinoma in protected environment-prophylactic antibiotic units.
    The American journal of medicine, 1984, Volume: 76, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Carcinoma, Bronch

1984
Experimental basis and clinical experience with non-cross-resistant combinations in solid tumours.
    Cancer treatment reviews, 1984, Volume: 11 Suppl A

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bro

1984
Combination chemotherapy with adriamycin, ifosfamide and mesna in extensive-stage non-small cell bronchogenic carcinoma.
    Cancer treatment reviews, 1983, Volume: 10 Suppl A

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Cyclophosphamide; Doxorubic

1983
N-acetylcysteine: its bioavailability and interaction with ifosfamide metabolites.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetates; Acetylcysteine; Biological Availability; Carcinoma, Bronchogenic; Chemical Phenomena; Chem

1983
[Combined cytostatic chemotherapy of advanced non-small-cell bronchial carcinoma with doxorubicin and ifosfamide].
    Deutsche medizinische Wochenschrift (1946), 1983, May-27, Volume: 108, Issue:21

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cyclophos

1983
The bioavailability of oral and intravenous ifosfamide in the treatment of bronchogenic carcinoma.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:11

    Topics: Administration, Oral; Adult; Biological Availability; Carcinoma, Bronchogenic; Cyclophosphamide; Fem

1981
Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:1

    Topics: Acetaldehyde; Adult; Aged; Carcinoma, Bronchogenic; Chromatography, Gas; Chromatography, High Pressu

1993
Ifosfamide with mesna uroprotection in the management of lung cancer.
    American journal of clinical oncology, 1990, Volume: 13, Issue:2

    Topics: Aged; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Female; Humans

1990
Comparative pharmacokinetics and alkylating activity of fractionated intravenous and oral ifosfamide in patients with bronchogenic carcinoma.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Administration, Oral; Adult; Aged; Alkylation; Carcinoma, Bronchogenic; Humans; Ifosfamide; Injectio

1989
Failure of response to ifosfamide in squamous cell bronchogenic carcinoma.
    Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:2

    Topics: Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Resistance; Humans; Ifosfamide; Lung Neoplas

1989
[Treatment of non-small-cell bronchial carcinoma with cisplatin, ifosfamide, vindesine and VP 16].
    Strahlentherapie, 1985, Volume: 161, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic

1985
[Chemotherapy with mitomycin C, vindesine and ifosfamide in the treatment of inoperable non-small cell bronchial carcinoma].
    Onkologie, 1985, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Drug

1985
Long-term effects of intravenous hyperalimentation administered during intensive chemotherapy for small cell bronchogenic carcinoma.
    Cancer, 1987, Jan-15, Volume: 59, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcino

1987
Ifosfamide and Mesna in advanced malignancies.
    Chinese medical journal, 1988, Volume: 101, Issue:3

    Topics: Adult; Aged; Carcinoma, Bronchogenic; Female; Hematuria; Humans; Ifosfamide; Lung Neoplasms; Lymphom

1988
Bioavailability of ifosfamide in patients with bronchial carcinoma.
    Cancer chemotherapy and pharmacology, 1986, Volume: 18, Issue:3

    Topics: Administration, Oral; Aged; Biological Availability; Carcinoma, Bronchogenic; Female; Humans; Ifosfa

1986