Page last updated: 2024-10-29

ifosfamide and Bilateral Wilms Tumor

ifosfamide has been researched along with Bilateral Wilms Tumor in 38 studies

Research Excerpts

ExcerptRelevanceReference
"This analysis was conducted to evaluate the efficacy and safety of carboplatin based chemotherapy in treating pediatric patients with Wilms tumors."8.90Clinical study on carboplatin for treating pediatric patients with Wilms tumors. ( Li, T; Mao, GJ; Sun, H; Sun, LL; Zhang, Y, 2014)
"Ifosfamide used in the treatment of pediatric solid tumors is known to have serious adverse effects, including acute pancreatitis, a rare complication of therapy."7.76Acute pancreatitis induced by ifosfamide therapy. ( Agarwala, S; Bhatnagar, V; Garg, R, 2010)
"The renal tubular Fanconi syndrome developed in five patients with Wilms tumor after treatment with ifosfamide, a derivative of cyclophosphamide."7.68Ifosfamide-induced renal tubular dysfunction and rickets in children with Wilms tumor. ( Burk, CD; Kaplan, BS; Meadows, AT; Restaino, I, 1990)
" The pharmacokinetic parameters for ifosfamide using model-independent methods were calculated: Vd = 0."6.40Toxicity, pharmacokinetics, and in vitro hemodialysis clearance of ifosfamide and metabolites in an anephric pediatric patient with Wilms' tumor. ( Bush, DA; Carlson, L; Goren, MP; Griener, JC; Kamen, BA; Quigley, R; Tkaczewski, I; Weitman, SD, 1998)
"Ifosfamide is a chemotherapeutic agent used for treatment of pediatric solid tumors."5.28Rickets--a complication of ifosfamide chemotherapy for Wilms tumor. ( Boal, DK; Relf, M, 1992)
"This analysis was conducted to evaluate the efficacy and safety of carboplatin based chemotherapy in treating pediatric patients with Wilms tumors."4.90Clinical study on carboplatin for treating pediatric patients with Wilms tumors. ( Li, T; Mao, GJ; Sun, H; Sun, LL; Zhang, Y, 2014)
"Phase II studies conducted in Europe and the USA on pediatric solid tumors have shown that ifosfamide, as a single agent, is an active drug against a variety of neoplasms - rhabdomyosarcoma (RMS), some non-RMS soft tissue sarcomas, Wilms' tumor, bone sarcomas and neuroblastoma."4.82Ifosfamide in pediatric solid tumors. ( Bisogno, G; Carli, M; Passone, E; Perilongo, G, 2003)
"The authors describe skin pigment changes in a 5-year-old patient receiving ifosfamide, MESNA, and etoposide for the treatment of relapsed Wilms tumor."4.78Ifosfamide-induced hyperpigmentation. ( Cornelius, AS; Murry, DJ; Teresi, ME, 1993)
"Ifosfamide used in the treatment of pediatric solid tumors is known to have serious adverse effects, including acute pancreatitis, a rare complication of therapy."3.76Acute pancreatitis induced by ifosfamide therapy. ( Agarwala, S; Bhatnagar, V; Garg, R, 2010)
"Neuroblastomas, nephroblastomas, malignant mesenchymal tumors, including rhabdomyosarcomas, Ewing's sarcomas, osteosarcomas, brain tumors, and non-Hodgkin's lymphomas respond to ifosfamide monotherapy."3.69Ifosfamide in the treatment of pediatric malignancies. ( Behrendt, H; de Kraker, J; Michiels, E; van den Berg, H; Voûte, PA, 1996)
"The renal tubular Fanconi syndrome developed in five patients with Wilms tumor after treatment with ifosfamide, a derivative of cyclophosphamide."3.68Ifosfamide-induced renal tubular dysfunction and rickets in children with Wilms tumor. ( Burk, CD; Kaplan, BS; Meadows, AT; Restaino, I, 1990)
"We studied two children with recurrent cancer, who during treatment with ifosfamide developed severe encephalopathy characterized by coma of several days duration."3.67Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors. ( Barak, LS; Estrada, J; Gieron, MA, 1988)
"Histopathological examination revealed nephroblastoma with lymph node metastasis."2.41[A case of adult Wilms' tumor]. ( Hanafusa, T; Hosokawa, Y; Kinouchi, T; Kotake, T; Kuroda, M; Maeda, O; Meguro, N; Saiki, S; Usami, M, 2001)
"Brain metastases are rare in the natural history of Wilms tumor."2.41Brain metastases in Wilms' tumor: case report and literature review. ( Grimard, L; Halton, JM; Hsu, E; MacRae, R; Nizalik, E, 2002)
" The pharmacokinetic parameters for ifosfamide using model-independent methods were calculated: Vd = 0."2.40Toxicity, pharmacokinetics, and in vitro hemodialysis clearance of ifosfamide and metabolites in an anephric pediatric patient with Wilms' tumor. ( Bush, DA; Carlson, L; Goren, MP; Griener, JC; Kamen, BA; Quigley, R; Tkaczewski, I; Weitman, SD, 1998)
"Adult extrarenal nephroblastomas (Wilms' tumor) are extremely rare tumors."1.37The first case of primary testicular germ cell tumor containing nephroblastoma as the only one non-germ cell component. ( Aksu, C; Başaran, M; Bavbek, S; Ekenel, M; Keskin, S; Kiliçaslan, I; Tunç, M, 2011)
"Teratoid Wilms' tumor is considered by some as a variant of Wilms' tumor containing at least 50% heterologous differentiated tissue."1.37Teratoid Wilms' tumor: case report of a rare variant that can mimic aggressive biology during chemotherapy. ( Raveesunthornkiet, M; Ruangtrakool, R; Sanpaki, K; Thorner, PS; Treetipsatit, J, 2011)
" Carboplatin dosage was based on glomerular filtration rate (GFR) to achieve targeted systemic exposure (6mg/ml min)."1.35Renal function after ifosfamide, carboplatin and etoposide (ICE) chemotherapy, nephrectomy and radiotherapy in children with Wilms tumour. ( Daw, NC; Gregornik, D; Jenkins, JJ; Jones, DP; Kun, LE; Marina, N; McPherson, V; Rodman, J; Wilimas, J; Wu, J, 2009)
" There was no compelling evidence for increased toxicity of doxorubicin when given at 100% versus 50% dosing (full dose: 20 mg/m(2) day x 3), but the number of patients analyzed was small."1.35Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group. ( Breslow, NE; Feusner, JH; Green, DM; Norkool, PA; Ritchey, ML; Takashima, JR, 2008)
"Spinal cord compression has also been rarely reported in all age groups."1.32Spinal cord compression and lung metastasis of Wilms' tumor in a pregnant adolescent. ( Akansel, G; Arisoy, AE; Calişkan, M; Corapcioglu, F; Dillioğlugil, O; Sarper, N, 2004)
"A diagnosis of bilateral Wilms tumor was made following percutaneous biopsy of both kidneys; histologic examination confirmed that the tumor was predominantly rhabdomyomatous."1.31Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor. ( Crooke, MJ; Delahunt, B; Lewis, ME; Pringle, KC; Wiltshire, EJ, 2001)
"Ifosfamide is a chemotherapeutic agent used for treatment of pediatric solid tumors."1.28Rickets--a complication of ifosfamide chemotherapy for Wilms tumor. ( Boal, DK; Relf, M, 1992)
"The ANH-nephroblastoma, however, could not be cured even with the highest tolerable doses of ifosfamide."1.26[Chemotherapeutic activity of ifosfamide in 6 different isologously transplanted experimental tumours of BD-rats (author's transl)]. ( Stekar, J, 1976)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's14 (36.84)18.2507
2000's10 (26.32)29.6817
2010's9 (23.68)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Groenendijk, A1
van Tinteren, H1
Jiang, Y1
de Krijger, RR1
Vujanic, GM1
Godzinski, J1
Rübe, C1
Schenk, JP1
Morosi, C1
Pritchard-Jones, K1
Al-Saadi, R1
Vaidya, SJ1
Verschuur, AC1
Ramírez-Villar, GL1
Graf, N3
de Camargo, B1
Drost, J1
Perotti, D1
van den Heuvel-Eibrink, MM1
Brok, J1
Spreafico, F1
Mavinkurve-Groothuis, AMC1
Zubowska, M1
Wyka, K1
Fendler, W1
Młynarski, W1
Zalewska-Szewczyk, B1
Zhang, Y1
Sun, LL1
Li, T1
Sun, H1
Mao, GJ1
Daw, NC1
Gregornik, D1
Rodman, J1
Marina, N1
Wu, J1
Kun, LE1
Jenkins, JJ2
McPherson, V1
Wilimas, J1
Jones, DP2
Sarhan, OM1
El-Baz, M1
Sarhan, MM1
Ghali, AM1
Ghoneim, MA1
Garg, R1
Agarwala, S1
Bhatnagar, V1
Kosmas, C1
Daladimos, T1
Athanasopoulos, A1
Theotikos, E1
Tsakonas, G1
Karabelis, A1
Mylonakis, N1
Yamagishi, A1
Sakurai, T1
Naito, S1
Tsukigi, M1
Kato, T1
Nagaoka, A1
Tomita, Y1
Iwaba, A1
Yamakawa, M1
Keskin, S1
Ekenel, M1
Başaran, M1
Aksu, C1
Kiliçaslan, I1
Tunç, M1
Bavbek, S1
Treetipsatit, J1
Raveesunthornkiet, M1
Ruangtrakool, R1
Sanpaki, K1
Thorner, PS1
Savaşan, S1
Sarnaik, SA1
Kremens, B1
Gruhn, B1
Klingebiel, T1
Hasan, C1
Laws, HJ1
Koscielniak, E1
Hero, B1
Selle, B1
Niemeyer, C1
Finckenstein, FG1
Schulz, A1
Wawer, A1
Zintl, F1
Carli, M1
Passone, E1
Perilongo, G1
Bisogno, G1
Corapcioglu, F1
Dillioğlugil, O1
Sarper, N1
Akansel, G1
Calişkan, M1
Arisoy, AE1
Keaney, CM1
Springate, JE1
Feusner, JH1
Ritchey, ML1
Norkool, PA1
Takashima, JR1
Breslow, NE1
Green, DM1
Cairo, MS2
Segal, LS1
Palumbo, RC1
Robertson, WW1
Marina, NM1
Wilimas, JA1
Meyer, WH2
Douglass, EC1
Pratt, CB2
Kiss, K1
Nagy, K1
Hunyadi, K1
Simkó, R1
Teresi, ME1
Murry, DJ1
Cornelius, AS1
Rossi, R1
Rath, B1
Ullrich, K1
Ehrich, JH1
Voûte, PA1
van den Berg, H1
Behrendt, H1
Michiels, E1
de Kraker, J1
Flentje, M1
Weirich, A1
Pötter, R1
Zimmerman, H1
Ludwig, R2
Carlson, L1
Goren, MP1
Bush, DA1
Griener, JC1
Quigley, R1
Tkaczewski, I1
Kamen, BA1
Weitman, SD1
Maurer, K1
Heitger, A1
Schwaighofer, H1
Fink, FM1
Niederweiser, D1
Delahunt, B1
Lewis, ME1
Pringle, KC1
Wiltshire, EJ1
Crooke, MJ1
Hosokawa, Y1
Saiki, S1
Hanafusa, T1
Meguro, N1
Maeda, O1
Kinouchi, T1
Kuroda, M1
Usami, M1
Kotake, T1
MacRae, R1
Grimard, L1
Hsu, E1
Nizalik, E1
Halton, JM1
Abu-Ghosh, AM1
Krailo, MD1
Goldman, SC1
Slack, RS1
Davenport, V1
Morris, E1
Laver, JH1
Reaman, GH1
Stekar, J1
Relf, M1
Boal, DK1
Avery, L1
McKay, CP1
Wyatt, RJ1
Hancock, ML1
Gutjahr, P1
Schwenger, M1
Spaar, HJ1
Michaelis, J1
Niethammer, D1
Jürgens, H1
Kühl, J1
Kutzner, J1
Schmidt, D1
Burk, CD1
Restaino, I1
Kaplan, BS1
Meadows, AT1
Tournade, MF2
Lemerle, J1
Brunat-Mentigny, M1
Bachelot, C1
Roche, H1
Taboureau, O1
Olive, D1
Lejars, O1
Boilletot, A1
Demeocq, F1
Gieron, MA1
Barak, LS1
Estrada, J1

Reviews

10 reviews available for ifosfamide and Bilateral Wilms Tumor

ArticleYear
Clinical study on carboplatin for treating pediatric patients with Wilms tumors.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:17

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Etoposide

2014
Bilateral Wilms' tumors: single-center experience with 22 cases and literature review.
    Urology, 2010, Volume: 76, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Child, Preschool; Com

2010
Double high-dose chemotherapy and stem cell transplantation in adult Wilms' tumor.
    Future oncology (London, England), 2010, Volume: 6, Issue:11

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2010
Ifosfamide in pediatric solid tumors.
    Oncology, 2003, Volume: 65 Suppl 2

    Topics: Antineoplastic Agents, Alkylating; Bone Neoplasms; Child; Cyclophosphamide; Germinoma; Humans; Ifosf

2003
Cancer and the kidney.
    Adolescent medicine clinics, 2005, Volume: 16, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Carcinoma, Renal Cell; Comorbi

2005
The use of ifosfamide, carboplatin, and etoposide in children with solid tumors.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Etoposide; Humans; Ifosfamide; L

1995
Ifosfamide-induced hyperpigmentation.
    Cancer, 1993, May-01, Volume: 71, Issue:9

    Topics: Child, Preschool; Etoposide; Humans; Ifosfamide; Kidney Neoplasms; Lung Neoplasms; Male; Mesna; Pigm

1993
Toxicity, pharmacokinetics, and in vitro hemodialysis clearance of ifosfamide and metabolites in an anephric pediatric patient with Wilms' tumor.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Drug Administration Schedule; Humans; Ifosfamide; Infant; Kidney

1998
[A case of adult Wilms' tumor].
    Hinyokika kiyo. Acta urologica Japonica, 2001, Volume: 47, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Female

2001
Brain metastases in Wilms' tumor: case report and literature review.
    Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Combined Modality Ther

2002

Trials

2 trials available for ifosfamide and Bilateral Wilms Tumor

ArticleYear
[Ifosfamide-induced nephrotoxicity].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1993, Volume: 141, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Child; Cisplatin; Creatinine

1993
Ifosfamide, carboplatin and etoposide in children with poor-risk relapsed Wilms' tumor: a Children's Cancer Group report.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2002, Volume: 13, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child, Preschool; Etoposide

2002

Other Studies

26 other studies available for ifosfamide and Bilateral Wilms Tumor

ArticleYear
Outcome of SIOP patients with low- or intermediate-risk Wilms tumour relapsing after initial vincristine and actinomycin-D therapy only - the SIOP 93-01 and 2001 protocols.
    European journal of cancer (Oxford, England : 1990), 2022, Volume: 163

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Dactinomycin; Disease-Free Survi

2022
Interleukin 18 as a marker of chronic nephropathy in children after anticancer treatment.
    Disease markers, 2013, Volume: 35, Issue:6

    Topics: Adolescent; Antineoplastic Agents; beta 2-Microglobulin; Biomarkers; Carboplatin; Child; Child, Pres

2013
Renal function after ifosfamide, carboplatin and etoposide (ICE) chemotherapy, nephrectomy and radiotherapy in children with Wilms tumour.
    European journal of cancer (Oxford, England : 1990), 2009, Volume: 45, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Carboplatin; Child; Child, Pre

2009
Acute pancreatitis induced by ifosfamide therapy.
    Journal of pediatric surgery, 2010, Volume: 45, Issue:10

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ca

2010
[Successful treatment of a case of advanced adult Wilms' tumor with pre-surgical chemotherapy, irradiation and radical nephrectomy].
    Hinyokika kiyo. Acta urologica Japonica, 2011, Volume: 57, Issue:4

    Topics: Adult; Androgen Antagonists; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplasti

2011
The first case of primary testicular germ cell tumor containing nephroblastoma as the only one non-germ cell component.
    Japanese journal of clinical oncology, 2011, Volume: 41, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin;

2011
Teratoid Wilms' tumor: case report of a rare variant that can mimic aggressive biology during chemotherapy.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dactinomycin; Disease Progression; Doxo

2011
Persistent elevation of fetal hemoglobin following chemotherapy in sickle cell disease.
    Pediatric blood & cancer, 2012, Jul-15, Volume: 59, Issue:1

    Topics: Anemia, Sickle Cell; Antineoplastic Combined Chemotherapy Protocols; Child; Dactinomycin; Doxorubici

2012
High-dose chemotherapy with autologous stem cell rescue in children with nephroblastoma.
    Bone marrow transplantation, 2002, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Combined Modal

2002
Spinal cord compression and lung metastasis of Wilms' tumor in a pregnant adolescent.
    Urology, 2004, Volume: 64, Issue:4

    Topics: Abdominal Pain; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carbopla

2004
Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cisplatin; Dactinomycin; Do

2008
The development of rickets as a complication of chemotherapy for the treatment of Wilms' tumor.
    Orthopedics, 1995, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bicarbonates; Calcitriol; Child; Child, Preschool; F

1995
Refining therapeutic strategies for patients with resistant Wilm's tumor.
    The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Ci

1994
[Nephropathy in patients treated with ifosfamide].
    Orvosi hetilap, 1994, May-08, Volume: 135, Issue:19

    Topics: Acidosis, Renal Tubular; Adolescent; Child; Child, Preschool; Fanconi Syndrome; Female; Humans; Ifos

1994
Ifosfamide in the treatment of pediatric malignancies.
    Seminars in oncology, 1996, Volume: 23, Issue:3 Suppl 7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms;

1996
Abdominal irradiation in unilateral nephroblastoma and its impact on local control and survival.
    International journal of radiation oncology, biology, physics, 1998, Jan-01, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined

1998
Double high-dose chemotherapy with autologous peripheral stem cell rescue in relapsed Wilms' tumor.
    Bone marrow transplantation, 1997, Volume: 20, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Dactinomycin; Doxo

1997
Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor.
    American journal of clinical pathology, 2001, Volume: 116, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Creatine Kinase; Dactinomycin; Di

2001
[Chemotherapeutic activity of ifosfamide in 6 different isologously transplanted experimental tumours of BD-rats (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:10

    Topics: Animals; Carcinosarcoma; Cyclophosphamide; Female; Ifosfamide; Male; Neoplasms, Experimental; Rats;

1976
Rickets--a complication of ifosfamide chemotherapy for Wilms tumor.
    Pediatric radiology, 1992, Volume: 22, Issue:3

    Topics: Child, Preschool; Humans; Ifosfamide; Kidney Neoplasms; Male; Neoplasm Recurrence, Local; Rickets; W

1992
Ifosfamide, Fanconi's syndrome, and rickets.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Chronic Kidney Disease-Mineral an

1991
[The importance of preoperative chemotherapy and radiotherapy in 373 children with Wilms' tumor].
    Deutsche medizinische Wochenschrift (1946), 1990, Feb-16, Volume: 115, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined

1990
Ifosfamide-induced renal tubular dysfunction and rickets in children with Wilms tumor.
    The Journal of pediatrics, 1990, Volume: 117, Issue:2 Pt 1

    Topics: Child; Child, Preschool; Chronic Kidney Disease-Mineral and Bone Disorder; Fanconi Syndrome; Female;

1990
A phase II study of ifosfamide in the treatment of relapses in Wilms' tumor.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24 Suppl 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Drug Evaluation; Drug Therapy, Combination; Humans; Ifos

1989
Ifosfamide is an active drug in Wilms' tumor: a phase II study conducted by the French Society of Pediatric Oncology.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Drug Evaluation; Female; Humans; Ifosfamide; Infant; Kid

1988
Severe encephalopathy associated with ifosfamide administration in two children with metastatic tumors.
    Journal of neuro-oncology, 1988, Volume: 6, Issue:1

    Topics: Brain Neoplasms; Child, Preschool; Coma; Electroencephalography; Female; Humans; Ifosfamide; Kidney

1988