Page last updated: 2024-10-29

ifosfamide and Atypical Lipomatous Tumor

ifosfamide has been researched along with Atypical Lipomatous Tumor in 23 studies

Research Excerpts

ExcerptRelevanceReference
"To evaluate the safety and efficacy of trabectedin in a phase II, open-label, multicenter, randomized study in adult patients with unresectable/metastatic liposarcoma or leiomyosarcoma after failure of prior conventional chemotherapy including anthracyclines and ifosfamide."9.14Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules. ( Baker, LH; Blay, JY; Chawla, SP; Demetri, GD; Elsayed, YA; Gómez, J; Hande, KR; Izquierdo, MA; Keohan, ML; Le Cesne, A; Lebedinsky, C; Park, YC; Ritch, P; Samuels, BL; Schuetze, S; von Mehren, M, 2009)
" The final diagnosis was liposarcoma(myxoid type), and 5 courses of adjuvant chemotherapy with adriamycin and ifosfamide were performed."7.77[A case of huge omental-origin liposarcoma controlled by a combination of ifosfamide and adriamycin]. ( Hosono, T; Kawamura, M; Kawamura, T; Murakami, K; Noguchi, T; Sasaki, K; Sato, R, 2011)
"To assess the impact of different factors on response rate (RR), time to tumor progression (TTP), and overall survival time (OS) in patients with locally advanced or metastatic soft tissue sarcoma (ASTS), included in three protocols with high-dose ifosfamide (HDIF)."7.72Salvage surgical resection after high-dose ifosfamide (HDIF) based regimens in advanced soft tissue sarcoma (ASTS): a potential positive selection bias--a study of the Spanish group for research on sarcomas (GEIS). ( Balañá, C; Buesa, J; Casado, A; de Las Peñas, R; del Muro, XG; López-Pousa, A; Martín, J; Martínez-Trufero, J; Maurel, J; Quintana, MJ, 2004)
"We report a case of retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide."7.70[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide]. ( Fujinami, K; Kondoh, I; Kondoh, K; Kushida, K; Miura, T, 1999)
"Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature."5.33A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide. ( Chuman, H; Ishiguro, S; Moriya, Y; Yamamoto, S, 2006)
"To evaluate the safety and efficacy of trabectedin in a phase II, open-label, multicenter, randomized study in adult patients with unresectable/metastatic liposarcoma or leiomyosarcoma after failure of prior conventional chemotherapy including anthracyclines and ifosfamide."5.14Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules. ( Baker, LH; Blay, JY; Chawla, SP; Demetri, GD; Elsayed, YA; Gómez, J; Hande, KR; Izquierdo, MA; Keohan, ML; Le Cesne, A; Lebedinsky, C; Park, YC; Ritch, P; Samuels, BL; Schuetze, S; von Mehren, M, 2009)
" Therefore, gemcitabine should be considered as the best option after doxorubicin failure in leiomyosarcoma patients."4.86[Chemotherapy options for patients with advanced soft-tissue sarcoma beyond anthracyclines]. ( Bui-Nguyen, B; Italiano, A; Toulmonde, M, 2010)
"We report a case of a 61-year-old Asian man with metastatic retroperitoneal liposarcoma who was HBcAb positive and was treated with ifosfamide and dacarbazine, developed HBV reactivation secondary to ifosfamide requiring treatment with tenofovir."3.83Hepatitis B Reactivation After Ifosfamide Therapy for Retroperitoneal Sarcoma. ( Chaudhry, R; Cheedella, NK; Chhibar, P; Wang, JC; Zhu, Z, 2016)
" The final diagnosis was liposarcoma(myxoid type), and 5 courses of adjuvant chemotherapy with adriamycin and ifosfamide were performed."3.77[A case of huge omental-origin liposarcoma controlled by a combination of ifosfamide and adriamycin]. ( Hosono, T; Kawamura, M; Kawamura, T; Murakami, K; Noguchi, T; Sasaki, K; Sato, R, 2011)
"We report a case of postoperative recurrence of liposarcoma of the mesenterium successfully treated by chemotherapy using ifosfamide (IFM) and cisplatin (CDDP)."3.73[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy]. ( Aoki, T; Kondo, M; Mizumura, Y; Moritani, M; Sasaki, Y; Tsuchida, A; Wada, T; Yamamoto, K, 2006)
"To assess the impact of different factors on response rate (RR), time to tumor progression (TTP), and overall survival time (OS) in patients with locally advanced or metastatic soft tissue sarcoma (ASTS), included in three protocols with high-dose ifosfamide (HDIF)."3.72Salvage surgical resection after high-dose ifosfamide (HDIF) based regimens in advanced soft tissue sarcoma (ASTS): a potential positive selection bias--a study of the Spanish group for research on sarcomas (GEIS). ( Balañá, C; Buesa, J; Casado, A; de Las Peñas, R; del Muro, XG; López-Pousa, A; Martín, J; Martínez-Trufero, J; Maurel, J; Quintana, MJ, 2004)
"We report a case of retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide."3.70[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide]. ( Fujinami, K; Kondoh, I; Kondoh, K; Kushida, K; Miura, T, 1999)
"Liposarcoma is very rare in female genital tract, and more rare for dedifferentiated liposarcoma in gynecologic field."1.62Primary dedifferentiated Liposarcoma of vagina: a first case report. ( Shen, Y; Xie, C, 2021)
"On multivariate analysis, metastasectomy and objective response or stable disease achieved with first-line chemotherapy were indicators for better overall survival."1.51Retrospective Analysis of Patients with Advanced Liposarcoma in a Tertiary Referral Center. ( Cornillie, J; Debiec-Rychter, M; Hompes, D; Langmans, C; Schöffski, P; Sciot, R; van Cann, T; Vandenbempt, I; Wozniak, A, 2019)
"Primary mesenteric liposarcoma is a rare entity that has been reported only 14 times in English literature."1.33A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide. ( Chuman, H; Ishiguro, S; Moriya, Y; Yamamoto, S, 2006)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's2 (8.70)18.2507
2000's9 (39.13)29.6817
2010's7 (30.43)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Nakahashi, K1
Yokoyama, Y1
Fukaya, M1
Igami, T1
Mizuno, T1
Yamaguchi, J1
Onoe, S1
Watanabe, N1
Ebata, T1
Stacchiotti, S1
Van der Graaf, WTA1
Sanfilippo, RG1
Marreaud, SI1
Van Houdt, WJ1
Judson, IR1
Gronchi, A1
Gelderblom, H1
Litiere, S1
Kasper, B1
Schöffski, P2
Blay, JY3
Xie, C1
Shen, Y1
Setola, E1
Noujaim, J1
Benson, C1
Chawla, S1
Palmerini, E1
Jones, RL1
Tatenuma, T1
Mizuno, N1
Jikuya, R1
Hashizume, A1
Yasui, M1
Umemoto, S1
Kawai, M1
Hiruma, T1
Kishida, T1
Langmans, C1
Cornillie, J1
van Cann, T1
Wozniak, A1
Hompes, D1
Sciot, R1
Debiec-Rychter, M1
Vandenbempt, I1
Chhibar, P1
Zhu, Z1
Cheedella, NK1
Chaudhry, R1
Wang, JC1
Fayette, J1
Penel, N1
Chevreau, C1
Cupissol, D1
Thyss, A1
Guillemet, C1
Rios, M1
Rolland, F1
Fargeot, P1
Bay, JO1
Mathoulin-Pelissier, S1
Coindre, JM1
Bui-Nguyen, B2
Berry, MF1
Sporn, TA1
Moore, JO1
D'Amico, TA1
Demetri, GD1
Chawla, SP1
von Mehren, M1
Ritch, P1
Baker, LH1
Hande, KR1
Keohan, ML1
Samuels, BL1
Schuetze, S1
Lebedinsky, C1
Elsayed, YA1
Izquierdo, MA1
Gómez, J1
Park, YC1
Le Cesne, A1
Yokoi, M1
Hosokawa, K1
Funaki, H1
Yoshitani, S1
Kinami, S1
Omote, K1
Ueda, N1
Nakano, Y1
Kosaka, T1
Minato, H1
Macmull, S1
Atkinson, HD1
Saso, S1
Tirabosco, R1
O'Donnell, P1
Skinner, JA1
Italiano, A1
Toulmonde, M1
Noguchi, T1
Kawamura, M1
Kawamura, T1
Sasaki, K1
Hosono, T1
Sato, R1
Murakami, K1
Eilber, FC1
Eilber, FR1
Eckardt, J1
Rosen, G1
Riedel, E1
Maki, RG1
Brennan, MF1
Singer, S1
Maurel, J1
Buesa, J1
López-Pousa, A1
del Muro, XG1
Quintana, MJ1
Martín, J1
Casado, A1
Martínez-Trufero, J1
de Las Peñas, R1
Balañá, C1
Sasaki, Y1
Moritani, M1
Wada, T1
Mizumura, Y1
Kondo, M1
Yamamoto, K1
Tsuchida, A1
Aoki, T1
Ishiguro, S1
Yamamoto, S1
Chuman, H1
Moriya, Y1
Izquierdo, R1
Leinung, M1
Fujinami, K1
Kondoh, K1
Kondoh, I1
Miura, T1
Kushida, K1
Boven, E1
Calame, JJ1
Molthoff, CF1
Pinedo, HM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Trabectedin in Soft Tissue Sarcomas. A Retrospective Observational Analysis (TrObs)[NCT02793050]510 participants (Actual)Observational2016-06-15Completed
ATREUS Trial - A Phase II Study on the Activity of Trabectedin of Pretreated Epithelioid or Biphasic / Sarcomatoid Malignant Pleural Mesothelioma(MPM)[NCT02194231]Phase 2145 participants (Actual)Interventional2013-07-31Completed
A Randomized Phase II Trial Comparing the Activity of trabectedIn vs Gemcitabine in Patients With Metastatic or Locally Advanced Leiomyosarcoma Pretreated With Conventional Chemotherapy[NCT04383119]Phase 2100 participants (Anticipated)Interventional2021-10-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for ifosfamide and Atypical Lipomatous Tumor

ArticleYear
Established and Experimental Systemic Treatment Options for Advanced Liposarcoma.
    Oncology research and treatment, 2022, Volume: 45, Issue:9

    Topics: Doxorubicin; Humans; Ifosfamide; Liposarcoma; Sarcoma; Trabectedin

2022
Eribulin in advanced liposarcoma and leiomyosarcoma.
    Expert review of anticancer therapy, 2017, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Doxorubicin; Furans; Humans; Ifosfamide; Ketones; Leiomyosarcoma; Li

2017
[Chemotherapy options for patients with advanced soft-tissue sarcoma beyond anthracyclines].
    Bulletin du cancer, 2010, Volume: 97, Issue:6

    Topics: Antineoplastic Agents; Dacarbazine; Deoxycytidine; Dioxoles; Docetaxel; Doxorubicin; Gemcitabine; Hu

2010

Trials

2 trials available for ifosfamide and Atypical Lipomatous Tumor

ArticleYear
Phase III trial of standard versus dose-intensified doxorubicin, ifosfamide and dacarbazine (MAID) in the first-line treatment of metastatic and locally advanced soft tissue sarcoma.
    Investigational new drugs, 2009, Volume: 27, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dose-Response Relationship

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Sep-01, Volume: 27, Issue:25

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents,

2009

Other Studies

18 other studies available for ifosfamide and Atypical Lipomatous Tumor

ArticleYear
A long-term survivor of advanced retroperitoneal dedifferentiated liposarcoma: a successful multimodal approach with extended resection and chemotherapy.
    Nagoya journal of medical science, 2022, Volume: 84, Issue:1

    Topics: Humans; Ifosfamide; Liposarcoma; Male; Middle Aged; Retroperitoneal Neoplasms; Survivors

2022
First-line chemotherapy in advanced intra-abdominal well-differentiated/dedifferentiated liposarcoma: An EORTC Soft Tissue and Bone Sarcoma Group retrospective analysis.
    Cancer, 2022, 08-01, Volume: 128, Issue:15

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms;

2022
Treatment of advanced soft tissue sarcoma by histological subtype: wish, prediction or reality?
    Future oncology (London, England), 2019, Volume: 15, Issue:26s

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Doxo

2019
Primary dedifferentiated Liposarcoma of vagina: a first case report.
    Diagnostic pathology, 2021, Jan-09, Volume: 16, Issue:1

    Topics: Adult; Antineoplastic Agents; Disease-Free Survival; Doxorubicin; Drug Therapy, Combination; Female;

2021
[RETROPERITONEAL LIPOSARCOMA WITH MULTIPLE RECURRENCE OF LUNG METASTASES TREATED BY MULTIMODAL THERAPY CENTERING ON THE OPERATION: A CASE REPORT].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2018, Volume: 109, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Etopo

2018
Retrospective Analysis of Patients with Advanced Liposarcoma in a Tertiary Referral Center.
    Oncology research and treatment, 2019, Volume: 42, Issue:7-8

    Topics: Adult; Aged; Antineoplastic Agents; Disease Progression; Doxorubicin; Female; Humans; Ifosfamide; Li

2019
Hepatitis B Reactivation After Ifosfamide Therapy for Retroperitoneal Sarcoma.
    The American journal of case reports, 2016, Jun-01, Volume: 17

    Topics: Antineoplastic Agents, Alkylating; Hepatitis B virus; Humans; Ifosfamide; Liposarcoma; Male; Middle

2016
Giant thoracic liposarcoma treated with induction chemotherapy followed by surgical resection.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2009, Volume: 4, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Human

2009
[A case of retroperitoneal dedifferentiated liposarcoma successfully treated with IFM and CDDP].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:12

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2009
Primary intra-osseous liposarcoma of the femur: a case report.
    Journal of orthopaedic surgery (Hong Kong), 2009, Volume: 17, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Combined Modality Therapy;

2009
[A case of huge omental-origin liposarcoma controlled by a combination of ifosfamide and adriamycin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Doxorubicin; Fatal Outcom

2011
The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma.
    Annals of surgery, 2004, Volume: 240, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Anti

2004
Salvage surgical resection after high-dose ifosfamide (HDIF) based regimens in advanced soft tissue sarcoma (ASTS): a potential positive selection bias--a study of the Spanish group for research on sarcomas (GEIS).
    Journal of surgical oncology, 2004, Oct-01, Volume: 88, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Bias; Clinical Trials,

2004
[A case of liposarcoma of the sigmoid colon mesenterium successfully treated with chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colon, Sigmoid; Drug Administration Sched

2006
A case of resected huge ileocolonic mesenteric liposarcoma which responded to pre-operative chemotherapy using doxorubicin, cisplatin and ifosfamide.
    Japanese journal of clinical oncology, 2006, Volume: 36, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug Administration S

2006
Hyponatraemia secondary to administration of ifosfamide.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:14

    Topics: Aged; Female; Head and Neck Neoplasms; Humans; Hyponatremia; Ifosfamide; Liposarcoma

1993
[A case of advanced retroperitoneal dedifferentiated liposarcoma treated effectively with high-dose ifosfamide].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

1999
Characterization and chemotherapy of human soft tissue sarcoma (STS) lines grown in nude mice.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1989, Volume: 165, Issue:7

    Topics: Animals; Cyclophosphamide; Doxorubicin; Female; Fibrosarcoma; Histiocytoma, Benign Fibrous; Humans;

1989