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ifosfamide and Agranulocytosis

ifosfamide has been researched along with Agranulocytosis in 15 studies

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"Phase II trial in metastatic urothelial carcinoma using a novel combination chemotherapy regimen consisting of vinblastine, ifosfamide, and gallium nitrate (VIG)."9.07Phase II trial of vinblastine, ifosfamide, and gallium combination chemotherapy in metastatic urothelial carcinoma. ( Ansari, R; Dreicer, R; Einhorn, LH; Gonin, R; Loehrer, PJ; Roth, BJ, 1994)
"The purpose of this study was to evaluate the activity of ifosfamide (isophosphamide) in patients with advanced or recurrent leiomyosarcoma not previously exposed to chemotherapy."7.68Phase II trial of ifosfamide and mesna in leiomyosarcoma of the uterus: a Gynecologic Oncology Group study. ( Barrett, RJ; Blessing, JA; McGehee, R; Sutton, GP, 1992)
"Phase II trial in metastatic urothelial carcinoma using a novel combination chemotherapy regimen consisting of vinblastine, ifosfamide, and gallium nitrate (VIG)."5.07Phase II trial of vinblastine, ifosfamide, and gallium combination chemotherapy in metastatic urothelial carcinoma. ( Ansari, R; Dreicer, R; Einhorn, LH; Gonin, R; Loehrer, PJ; Roth, BJ, 1994)
"The purpose of this study was to evaluate the activity of ifosfamide (isophosphamide) in patients with advanced or recurrent leiomyosarcoma not previously exposed to chemotherapy."3.68Phase II trial of ifosfamide and mesna in leiomyosarcoma of the uterus: a Gynecologic Oncology Group study. ( Barrett, RJ; Blessing, JA; McGehee, R; Sutton, GP, 1992)
"The pharmacokinetics of ifosfamide were studied in 20 patients with soft tissue and bone sarcomas."3.68Clinical pharmacokinetics of ifosfamide in combination with N-acetylcysteine. ( Ayele, W; Benvenuto, JA; Legha, SS; Newman, RA; Nicaise, C; Raber, MN, 1992)
"Grade 3 thrombocytopenia was observed in five cases (36%)."2.71Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer: a preliminary report. ( Kitamura, T; Kume, H; Matsumoto, S; Nishimatsu, H; Okamoto, N; Suzuki, M; Takahashi, S; Tomita, K, 2005)
"Granulocytopenia was the dose-limiting toxicity."2.68Phase I study of paclitaxel, cisplatin, and ifosfamide in patients with recurrent or metastatic squamous cell cancer of the head and neck. ( Benner, SE; Hong, WK; Huber, MH; Lippman, SM, 1995)
"Paclitaxel dose levels were 135, 170, 200, 250, and 300 mg/m2."2.68Paclitaxel and ifosfamide: a multicenter phase I study in advanced non-small cell lung cancer. ( Bitran, JD; Drinkard, LC; Golomb, HM; Hoffman, PC; Krauss, SA; Masters, GA; Samuels, BL; Vokes, EE; Watson, S, 1995)
"Ifosfamide is an active agent in recurrent squamous cell carcinoma of the head and neck."2.68A phase II study of ifosfamide in recurrent squamous cell carcinoma of the head and neck. ( Benner, SE; Dimery, IW; Dunnington, JS; Hong, WK; Huber, MH; Lippman, SM; Shirinian, M, 1996)
"Ifosfamide has shown promising single-agent activity in non-small cell lung cancer (NSCLC)."1.28Phase II study of cisplatin, ifosfamide with mesna, and etoposide (PIE) chemotherapy for advanced non-small cell lung cancer. ( Dhingra, HH; Greenberg, J; Hong, WK; Lee, JS; Shirinian, M, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (86.67)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takahashi, S1
Suzuki, M1
Kume, H1
Matsumoto, S1
Okamoto, N1
Nishimatsu, H1
Tomita, K1
Kitamura, T1
Benner, SE2
Lippman, SM2
Huber, MH2
Hong, WK3
Einhorn, LH2
Roth, BJ1
Ansari, R2
Dreicer, R1
Gonin, R2
Loehrer, PJ2
Hoffman, PC1
Krauss, SA1
Drinkard, LC1
Masters, GA1
Samuels, BL1
Bitran, JD1
Golomb, HM1
Watson, S1
Vokes, EE1
Faylona, EA1
Sandler, AB1
Evans, WK2
Stewart, DJ1
Shepherd, FA2
Logan, D2
Goss, G1
Maroun, JA1
Wierzbicki, R1
Warner, E2
Latreille, J2
Dahrouge, S1
Shirinian, M2
Dimery, IW1
Dunnington, JS1
Haim, N1
Ben-Shahar, M1
Faraggi, D1
Tsuri-Etzioni, A1
Leviov, M1
Epelbaum, R1
Kleiner, S1
Kirsch, A1
Schwaner, I1
Kingreen, D1
Schwella, N1
Huhn, D1
Siegert, W1
Dodd, PM1
McCaffrey, JA1
Hilton, S1
Mazumdar, M1
Herr, H1
Kelly, WK1
Icasiano, E1
Boyle, MG1
Bajorin, DF1
Lee, JS1
Dhingra, HH1
Greenberg, J1
Goss, PE1
Maroun, J1
Stewart, D1
Paul, K1
Sutton, GP1
Blessing, JA1
Barrett, RJ1
McGehee, R1
Benvenuto, JA1
Ayele, W1
Legha, SS1
Raber, MN1
Nicaise, C1
Newman, RA1
Ohnoshi, T1
Ueoka, H1
Kodani, T1
Kamei, H1
Kimura, I1

Trials

10 trials available for ifosfamide and Agranulocytosis

ArticleYear
Combination chemotherapy of docetaxel, ifosfamide and cisplatin (DIP) in patients with metastatic urothelial cancer: a preliminary report.
    Japanese journal of clinical oncology, 2005, Volume: 35, Issue:2

    Topics: Aged; Aged, 80 and over; Agranulocytosis; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bo

2005
Phase I study of paclitaxel, cisplatin, and ifosfamide in patients with recurrent or metastatic squamous cell cancer of the head and neck.
    Seminars in oncology, 1995, Volume: 22, Issue:5 Suppl 12

    Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcin

1995
Phase II trial of vinblastine, ifosfamide, and gallium combination chemotherapy in metastatic urothelial carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Cal

1994
Paclitaxel and ifosfamide: a multicenter phase I study in advanced non-small cell lung cancer.
    Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-C

1995
Phase II study of daily oral etoposide plus ifosfamide plus cisplatin for previously treated recurrent small-cell lung cancer: a Hoosier Oncology Group Trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:5

    Topics: Administration, Oral; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcino

1995
A phase II study of ifosfamide in recurrent squamous cell carcinoma of the head and neck.
    American journal of clinical oncology, 1996, Volume: 19, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents, Alkylating; Carcinoma, Squamous Cell; Female; H

1996
Dexamethasone, etoposide, ifosfamide, and cisplatin as second-line therapy in patients with aggressive non-Hodgkin's lymphoma.
    Cancer, 1997, Nov-15, Volume: 80, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Combined Chemotherapy P

1997
High-dose chemotherapy with carboplatin, etoposide and ifosfamide followed by autologous stem cell rescue in patients with relapsed or refractory malignant lymphomas: a phase I/II study.
    Bone marrow transplantation, 1997, Volume: 20, Issue:11

    Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Tran

1997
Phase I evaluation of sequential doxorubicin gemcitabine then ifosfamide paclitaxel cisplatin for patients with unresectable or metastatic transitional-cell carcinoma of the urothelial tract.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:4

    Topics: Aged; Agranulocytosis; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic

2000
[Effect of recombinant human granulocyte colony-stimulating factor (rG-CSF) on chemotherapy-induced neutropenia in patients with lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:4 Pt 2

    Topics: Adenocarcinoma; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, No

1990

Other Studies

5 other studies available for ifosfamide and Agranulocytosis

ArticleYear
VP-16, ifosfamide and cisplatin (VIP) for extensive small cell lung cancer.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:3

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell;

1994
Phase II study of cisplatin, ifosfamide with mesna, and etoposide (PIE) chemotherapy for advanced non-small cell lung cancer.
    Seminars in oncology, 1992, Volume: 19, Issue:1 Suppl 1

    Topics: Adenocarcinoma; Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Carcin

1992
Ifosfamide, cisplatin, and etoposide (ICE) in the treatment of advanced non-small cell lung cancer.
    Seminars in oncology, 1992, Volume: 19, Issue:1 Suppl 1

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma

1992
Phase II trial of ifosfamide and mesna in leiomyosarcoma of the uterus: a Gynecologic Oncology Group study.
    American journal of obstetrics and gynecology, 1992, Volume: 166, Issue:2

    Topics: Adult; Aged; Agranulocytosis; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Ifosfamide

1992
Clinical pharmacokinetics of ifosfamide in combination with N-acetylcysteine.
    Anti-cancer drugs, 1992, Volume: 3, Issue:1

    Topics: Acetylcysteine; Agranulocytosis; Bone Marrow; Humans; Ifosfamide; Sarcoma

1992