ifosfamide has been researched along with Aging in 8 studies
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To assess the impact of adjuvant chemotherapy, we reviewed the overall survival of consecutive patients with anaplastic ependymoma treated over a 10-year period with surgery and ICE (ifosfamide+ VP 16+carboplatin) chemotherapy with or without radiation at our institution." | 3.70 | Use of adjuvant ICE chemotherapy in the treatment of anaplastic ependymomas. ( Baruchel, S; Chan, H; Fouladi, M; Grant, R; Greenberg, ML; Malkin, D; Weitzman, S, 1998) |
| "Ifosfamide has been in use as an effective antineoplastic agent for solid tumors in both children and adults since the late 1960s." | 2.41 | Young age and the risk for ifosfamide-induced nephrotoxicity: a critical review of two opposing studies. ( Aleksa, K; Koren, G; Woodland, C, 2001) |
| "Ifosfamide is a prodrug that requires biotransformation to become cytotoxic." | 2.39 | Ifosfamide clinical pharmacokinetics. ( Wagner, T, 1994) |
| " This will adversely affect the health and well-being of children, especially when the developing kidney is exposed to toxic agents that may lead to acute glomerular, tubular or combined toxicity." | 1.33 | Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity. ( Aleksa, K; Gelboin, H; Ito, S; Koren, G; Krausz, K; Matsell, D, 2005) |
| " A positive correlation was found between the elimination half-life of ifosfamide and age (r = 0." | 1.28 | The effect of age on the pharmacokinetics of ifosfamide. ( Cerny, T; Lind, MJ; Margison, JM; Thatcher, N; Wilkinson, PM, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Misiura, K | 1 |
| Zubowska, M | 1 |
| Zielińska, E | 1 |
| Aleksa, K | 3 |
| Matsell, D | 1 |
| Krausz, K | 1 |
| Gelboin, H | 1 |
| Ito, S | 2 |
| Koren, G | 3 |
| Wagner, T | 1 |
| Fouladi, M | 1 |
| Baruchel, S | 1 |
| Chan, H | 1 |
| Grant, R | 1 |
| Malkin, D | 1 |
| Weitzman, S | 1 |
| Greenberg, ML | 1 |
| Woodland, C | 1 |
| Lewis, LD | 1 |
| Lind, MJ | 1 |
| Margison, JM | 1 |
| Cerny, T | 1 |
| Thatcher, N | 1 |
| Wilkinson, PM | 1 |
3 reviews available for ifosfamide and Aging
| Article | Year |
|---|---|
Ifosfamide clinical pharmacokinetics.
Topics: Administration, Oral; Aging; Animals; Central Nervous System; Drug Interactions; Half-Life; Humans; | 1994 |
Young age and the risk for ifosfamide-induced nephrotoxicity: a critical review of two opposing studies.
Topics: Aging; Dose-Response Relationship, Drug; Humans; Ifosfamide; Immunosuppressive Agents; Kidney; Risk | 2001 |
Ifosfamide pharmacokinetics.
Topics: Administration, Oral; Aging; Brain Diseases; Dose-Response Relationship, Drug; Humans; Ifosfamide | 1991 |
1 trial available for ifosfamide and Aging
| Article | Year |
|---|---|
Analysis of the urinary excretion of ifosfamide and its N-dechloroethylated metabolites in children using 31P-NMR spectroscopy.
Topics: Adolescent; Aging; Antineoplastic Agents, Alkylating; Biotransformation; Child; Child, Preschool; Fe | 2003 |
4 other studies available for ifosfamide and Aging
| Article | Year |
|---|---|
Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antibodies, Monoclonal; Antineoplastic Agents, Al | 2005 |
Enantioselective metabolism of ifosfamide by the kidney.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aging; Animals; Antineoplastic Agents, | 2006 |
Use of adjuvant ICE chemotherapy in the treatment of anaplastic ependymomas.
Topics: Aging; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cerebellar Neoplasms; Child; Chi | 1998 |
The effect of age on the pharmacokinetics of ifosfamide.
Topics: Adult; Aged; Aging; Body Water; Carcinoma, Non-Small-Cell Lung; Half-Life; Humans; Ifosfamide; Lung | 1990 |