ifosfamide has been researched along with Acute Liver Injury, Drug-Induced in 12 studies
Excerpt | Relevance | Reference |
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"Morin is a flavonoid and broadly found in white berry and cranberry branch." | 1.72 | The protective effect of Morin against ifosfamide-induced acute liver injury in rats associated with the inhibition of DNA damage and apoptosis. ( Çomaklı, S; Kandemir, FM; Kucukler, S; Özdemir, S, 2022) |
"Ifosfamide is an alkylating agent, a synthetic analogue of cyclophosphamide, used to treat various solid cancers." | 1.62 | Investigation of Ifosfamide Toxicity Induces Common Upstream Regulator in Liver and Kidney. ( Choi, MS; Han, HY; Kim, SK; Kim, TW; Ko, JW; Yoon, S, 2021) |
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (8.33) | 18.7374 |
1990's | 1 (8.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 8 (66.67) | 24.3611 |
2020's | 2 (16.67) | 2.80 |
Authors | Studies |
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Fourches, D | 1 |
Barnes, JC | 1 |
Day, NC | 1 |
Bradley, P | 1 |
Reed, JZ | 1 |
Tropsha, A | 1 |
Greene, N | 1 |
Fisk, L | 1 |
Naven, RT | 1 |
Note, RR | 1 |
Patel, ML | 1 |
Pelletier, DJ | 1 |
Ekins, S | 1 |
Williams, AJ | 1 |
Xu, JJ | 1 |
Chen, M | 2 |
Vijay, V | 1 |
Shi, Q | 2 |
Liu, Z | 2 |
Fang, H | 2 |
Tong, W | 3 |
Ding, D | 1 |
Kelly, R | 1 |
Morgan, RE | 1 |
van Staden, CJ | 1 |
Chen, Y | 1 |
Kalyanaraman, N | 1 |
Kalanzi, J | 1 |
Dunn, RT | 1 |
Afshari, CA | 1 |
Hamadeh, HK | 1 |
Suzuki, A | 1 |
Thakkar, S | 1 |
Yu, K | 1 |
Hu, C | 1 |
Han, HY | 1 |
Choi, MS | 1 |
Yoon, S | 1 |
Ko, JW | 1 |
Kim, SK | 1 |
Kim, TW | 1 |
Özdemir, S | 1 |
Kucukler, S | 1 |
Çomaklı, S | 1 |
Kandemir, FM | 1 |
Mian, M | 1 |
Farsad, M | 1 |
Pescosta, N | 1 |
Casini, M | 1 |
Cavattoni, IM | 1 |
Deola, S | 1 |
Cortelazzo, S | 1 |
Urban, C | 1 |
Benesch, M | 1 |
Pakisch, B | 1 |
Lackner, H | 1 |
Kerbl, R | 1 |
Schwinger, W | 1 |
Oberbauer, R | 1 |
Paschke, R | 1 |
Worst, P | 1 |
Brust, J | 1 |
Queisser, W | 1 |
1 review available for ifosfamide and Acute Liver Injury, Drug-Induced
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
1 trial available for ifosfamide and Acute Liver Injury, Drug-Induced
Article | Year |
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Synchronous radiochemotherapy in unfavorable brain tumors of children and young adults.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Che | 1998 |
10 other studies available for ifosfamide and Acute Liver Injury, Drug-Induced
Article | Year |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Investigation of Ifosfamide Toxicity Induces Common Upstream Regulator in Liver and Kidney.
Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Ifosfamide; Kidney; Kid | 2021 |
The protective effect of Morin against ifosfamide-induced acute liver injury in rats associated with the inhibition of DNA damage and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; DNA Damage; Flavonoids; Gl | 2022 |
Bendamustine salvage for the treatment of relapsed Hodgkin's lymphoma after allogeneic bone marrow transplantation.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Alkylating; Antineoplastic Combined C | 2013 |
[Hepatotoxicity with etoposide-ifosfamide combination therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cel | 1988 |