ifenprodil has been researched along with Stroke in 3 studies
ifenprodil: NMDA receptor antagonist
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this context, we analyzed the effect of Ifenprodil, an NR2b selective NMDAR antagonist and its combination at lower doses with flurbiprofen, a selective ASIC1a inhibitor on rat model of focal cerebral ischemia." | 3.77 | The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury. ( Mishra, V; Raghubir, R; Singh, N; Verma, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Q | 1 |
| Hu, M | 1 |
| Li, J | 1 |
| Ma, X | 1 |
| Chu, Z | 1 |
| Zhu, Q | 1 |
| Zhang, Y | 1 |
| Zhu, P | 1 |
| Huang, Y | 1 |
| He, G | 1 |
| Mishra, V | 1 |
| Verma, R | 1 |
| Singh, N | 1 |
| Raghubir, R | 1 |
| Bhattacharya, P | 1 |
| Pandey, AK | 1 |
| Paul, S | 1 |
| Patnaik, R | 1 |
3 other studies available for ifenprodil and Stroke
| Article | Year |
|---|---|
Discovery of novel brain-penetrant GluN2B NMDAR antagonists via pharmacophore-merging strategy as anti-stroke therapeutic agents.
Topics: Benzofurans; Brain; Dose-Response Relationship, Drug; Drug Discovery; Humans; Molecular Structure; N | 2022 |
The neuroprotective effects of NMDAR antagonist, ifenprodil and ASIC1a inhibitor, flurbiprofen on post-ischemic cerebral injury.
Topics: Animals; Apoptosis; Brain Ischemia; Drug Therapy, Combination; Flurbiprofen; In Situ Nick-End Labeli | 2011 |
Combination therapy of ifenprodil with piroxicam may be an effective therapeutic intervention in cerebral stroke: a hypothesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Humans; Models, Neurolo | 2012 |