ifenprodil has been researched along with Status Epilepticus in 3 studies
ifenprodil: NMDA receptor antagonist
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ifenprodil (20 mg/kg) was administered intraperitoneally (ip) after the stimulation with 3." | 5.48 | Does status epilepticus modify the effect of ifenprodil on cortical epileptic afterdischarges in immature rats? ( Abbasova, K; Kubová, H; Mareš, P, 2018) |
| "Ifenprodil (20 mg/kg) was administered intraperitoneally (ip) after the stimulation with 3." | 1.48 | Does status epilepticus modify the effect of ifenprodil on cortical epileptic afterdischarges in immature rats? ( Abbasova, K; Kubová, H; Mareš, P, 2018) |
| "Ifenprodil was maximally effective at 30 mg/kg." | 1.32 | A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus. ( Bertram, EH; Kapur, J; Williamson, J; Yen, W, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbasova, K | 1 |
| Kubová, H | 1 |
| Mareš, P | 1 |
| Yen, W | 1 |
| Williamson, J | 1 |
| Bertram, EH | 1 |
| Kapur, J | 1 |
| Ding, S | 1 |
| Fellin, T | 1 |
| Zhu, Y | 1 |
| Lee, SY | 1 |
| Auberson, YP | 1 |
| Meaney, DF | 1 |
| Coulter, DA | 1 |
| Carmignoto, G | 1 |
| Haydon, PG | 1 |
3 other studies available for ifenprodil and Status Epilepticus
| Article | Year |
|---|---|
Does status epilepticus modify the effect of ifenprodil on cortical epileptic afterdischarges in immature rats?
Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Brain Waves; Cerebral Cortex; Disease Model | 2018 |
A comparison of three NMDA receptor antagonists in the treatment of prolonged status epilepticus.
Topics: Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Ami | 2004 |
Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus.
Topics: Animals; Anticonvulsants; Astrocytes; Calcium; Calcium Signaling; Cell Death; Chelating Agents; Dise | 2007 |