Page last updated: 2024-10-28

ifenprodil and Neuralgia

ifenprodil has been researched along with Neuralgia in 7 studies

ifenprodil: NMDA receptor antagonist

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Ifenprodil was administered in PDN rats while saline was administered intrathecally in the control group."1.62Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2021)
"NMDA antagonists effectively reduce neuropathic pain, but serious side effects prevent their use as therapeutic drugs."1.38Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models. ( Ahn, YJ; Cho, HY; Kim, J; Kim, Y; Yoon, YW, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Tewes, B1
Frehland, B1
Schepmann, D1
Schmidtke, KU1
Winckler, T1
Wünsch, B1
Ismail, CAN1
Suppian, R1
Ab Aziz, CB1
Long, I1
Ferrier, J1
Bayet-Robert, M1
Pereira, B1
Daulhac, L1
Eschalier, A1
Pezet, D1
Moulinoux, JP1
Balayssac, D1
Tong, CK1
MacDermott, AB1
Wang, W2
Mei, XP1
Wei, YY1
Zhang, MM1
Zhang, T1
Xu, LX1
Wu, SX1
Li, YQ1
Kim, Y1
Cho, HY1
Ahn, YJ1
Kim, J1
Yoon, YW1
Iwata, H1
Takasusuki, T1
Yamaguchi, S1
Hori, Y1

Other Studies

7 other studies available for ifenprodil and Neuralgia

ArticleYear
Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.
    Bioorganic & medicinal chemistry, 2010, Nov-15, Volume: 18, Issue:22

    Topics: Analgesics; Animals; Benzazepines; Humans; Mice; Microsomes, Liver; Neuralgia; Piperidines; Rats; Re

2010
Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetic Neuropathies; Formaldehyde; Kv Channel-Interact

2021
A polyamine-deficient diet prevents oxaliplatin-induced acute cold and mechanical hypersensitivity in rats.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Acute Disease; Animals; Antineoplastic Agents; Behavior, Animal; Cold Temperature; Diet; Glutamic Ac

2013
Synaptic GluN2A and GluN2B containing NMDA receptors within the superficial dorsal horn activated following primary afferent stimulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-13, Volume: 34, Issue:33

    Topics: Animals; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Male; Neural

2014
Neuronal NR2B-containing NMDA receptor mediates spinal astrocytic c-Jun N-terminal kinase activation in a rat model of neuropathic pain.
    Brain, behavior, and immunity, 2011, Volume: 25, Issue:7

    Topics: Animals; Astrocytes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hype

2011
Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models.
    Pain, 2012, Volume: 153, Issue:5

    Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Male; Neuralgia; Pain Measurement; Phe

2012
NMDA receptor 2B subunit-mediated synaptic transmission in the superficial dorsal horn of peripheral nerve-injured neuropathic mice.
    Brain research, 2007, Mar-02, Volume: 1135, Issue:1

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agents; Excitatory Postsyna

2007