ifenprodil has been researched along with Diabetic Neuropathies in 2 studies
ifenprodil: NMDA receptor antagonist
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ifenprodil was administered in PDN rats while saline was administered intrathecally in the control group." | 1.62 | Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats. ( Ab Aziz, CB; Ismail, CAN; Long, I; Suppian, R, 2021) |
| "Ifenprodil treatment for both doses showed anti-allodynic and anti-nociceptive effects with lower expression of phosphorylated and total spinal NR2B." | 1.51 | Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of ( Abd Aziz, CB; Haris, K; Ismail, CAN; Long, I; Suppian, R, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, CAN | 2 |
| Suppian, R | 2 |
| Ab Aziz, CB | 1 |
| Long, I | 2 |
| Abd Aziz, CB | 1 |
| Haris, K | 1 |
2 other studies available for ifenprodil and Diabetic Neuropathies
| Article | Year |
|---|---|
Ifenprodil Reduced Expression of Activated Microglia, BDNF and DREAM Proteins in the Spinal Cord Following Formalin Injection During the Early Stage of Painful Diabetic Neuropathy in Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Diabetic Neuropathies; Formaldehyde; Kv Channel-Interact | 2021 |
Increased Nociceptive Responses in Streptozotocin-Induced Diabetic Rats and the Related Expression of Spinal NR2B Subunit of
Topics: Analgesics; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disea | 2019 |