ifenprodil has been researched along with Atherosclerotic Parkinsonism in 4 studies
ifenprodil: NMDA receptor antagonist
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatments for Parkinson's disease based on replacement of lost dopamine have several problems." | 1.31 | Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat. ( Brotchie, JM; Nash, JE, 2002) |
| " Compound 11a also potentiated the effects of L-DOPA in a rat model of Parkinson's disease (the 6-hydroxydopamine-lesioned rat), dosed at 30 mg/kg orally." | 1.31 | Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements. ( Meltzer, LT; Schelkun, RM; Serpa, K; Whittemore, ER; Wise, LD; Woodward, RM; Yuen, PW, 2000) |
| "In animal models of Parkinson's disease, loss of striatal dopamine leads to enhanced excitation of striatal NR2B-containing NMDA receptors." | 1.31 | Antiparkinsonian actions of ifenprodil in the MPTP-lesioned marmoset model of Parkinson's disease. ( Brotchie, JM; Crossman, AR; Fox, SH; Henry, B; Hill, MP; Hille, C; Maneuf, Y; McGuire, S; Nash, JE; Peggs, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nash, JE | 3 |
| Brotchie, JM | 3 |
| Hill, MP | 2 |
| Schelkun, RM | 1 |
| Yuen, PW | 1 |
| Serpa, K | 1 |
| Meltzer, LT | 1 |
| Wise, LD | 1 |
| Whittemore, ER | 1 |
| Woodward, RM | 1 |
| Fox, SH | 1 |
| Henry, B | 1 |
| Peggs, D | 1 |
| McGuire, S | 1 |
| Maneuf, Y | 1 |
| Hille, C | 1 |
| Crossman, AR | 1 |
4 other studies available for ifenprodil and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Characterisation of striatal NMDA receptors involved in the generation of parkinsonian symptoms: intrastriatal microinjection studies in the 6-OHDA-lesioned rat.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Corpus Striatum; Dopamine; Dose-Response Relationsh | 2002 |
Antiparkinsonian actions of blockade of NR2B-containing NMDA receptors in the reserpine-treated rat.
Topics: Animals; Antiparkinson Agents; Binding, Competitive; Corpus Striatum; Dizocilpine Maleate; Dose-Resp | 1999 |
Subtype-selective N-methyl-D-aspartate receptor antagonists: benzimidazalone and hydantoin as phenol replacements.
Topics: Animals; Benzimidazoles; Electrophysiology; Excitatory Amino Acid Antagonists; Hydantoins; Hydrogen | 2000 |
Antiparkinsonian actions of ifenprodil in the MPTP-lesioned marmoset model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Behavior, Animal; Calli | 2000 |