Page last updated: 2024-10-28

ifenprodil and Ache

ifenprodil has been researched along with Ache in 7 studies

ifenprodil: NMDA receptor antagonist

Research Excerpts

ExcerptRelevanceReference
" Intrathecal administration of 5 and 10 microg of NR2B subunit-specific NMDA receptor antagonist ifenprodil attenuated cancer-evoked spontaneous pain, thermal hyperalgesia and mechanical allodynia."3.76The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain. ( Gao, Q; Gu, X; Jin, Y; Ma, Z; Mei, F; Wang, J; Xia, X; Zhang, J; Zhou, X, 2010)
" Ifenprodil and some other NMDA antagonists (MK-801, memantine) were tested in a model of inflammatory pain (Randall-Selitto) in rats."3.71Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil. ( Chizh, BA; Englberger, W; Haase, G; Reissmüller, E; Scheede, M; Schlütz, H, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mony, L1
Kew, JN1
Gunthorpe, MJ1
Paoletti, P1
Gu, X1
Zhang, J1
Ma, Z1
Wang, J1
Zhou, X1
Jin, Y1
Xia, X1
Gao, Q1
Mei, F1
Fischer, BD1
Carrigan, KA1
Dykstra, LA1
Gogas, KR1
Tan-No, K1
Esashi, A1
Nakagawasai, O1
Niijima, F1
Furuta, S1
Sato, T1
Satoh, S1
Yasuhara, H1
Tadano, T1
Chizh, BA1
Reissmüller, E1
Schlütz, H1
Scheede, M1
Haase, G1
Englberger, W1
Green, GM1
Gibb, AJ1

Reviews

2 reviews available for ifenprodil and Ache

ArticleYear
Allosteric modulators of NR2B-containing NMDA receptors: molecular mechanisms and therapeutic potential.
    British journal of pharmacology, 2009, Volume: 157, Issue:8

    Topics: Allosteric Regulation; Allosteric Site; Animals; Brain Diseases; Depressive Disorder, Major; Humans;

2009
Glutamate-based therapeutic approaches: NR2B receptor antagonists.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:1

    Topics: Animals; Brain Ischemia; Clinical Trials as Topic; Disease Models, Animal; Excitatory Amino Acid Ant

2006

Other Studies

5 other studies available for ifenprodil and Ache

ArticleYear
The role of N-methyl-D-aspartate receptor subunit NR2B in spinal cord in cancer pain.
    European journal of pain (London, England), 2010, Volume: 14, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Cells, Cultured;

2010
Effects of N-methyl-D-aspartate receptor antagonists on acute morphine-induced and l-methadone-induced antinociception in mice.
    The journal of pain, 2005, Volume: 6, Issue:7

    Topics: Analgesia; Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Dr

2005
Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Agmatine; Animals; Cycloserine; Dizocilpine Maleate; Dose-Response Rela

2007
Supraspinal vs spinal sites of the antinociceptive action of the subtype-selective NMDA antagonist ifenprodil.
    Neuropharmacology, 2001, Volume: 40, Issue:2

    Topics: Analgesics; Animals; Decerebrate State; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino

2001
Characterization of the single-channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord.
    The European journal of neuroscience, 2001, Volume: 14, Issue:10

    Topics: Aging; Animals; Excitatory Amino Acid Antagonists; Ion Channels; Magnesium; Membrane Potentials; N-M

2001