iduronate and Keloid
iduronate has been researched along with Keloid* in 1 studies
Other Studies
1 other study(ies) available for iduronate and Keloid
| Article | Year |
|---|---|
Purification and characterization of iduronic acid-rich and glucuronic acid-rich proteoglycans implicated in human post-burn keloid scar.
Small proteoglycans (PGs), extracted from human keloid scar tissue with 4M guanidinium chloride and fractionated by DEAE-cellulose chromatography, were separated by ethanol precipitation into one L-iduronic acid-rich and one D-glucuronic acid-rich fraction. The size of the L-iduronic acid-rich PG was 102 kDa with a 27 kDa glycosaminoglycan chain, that of the D-glucuronic acid-rich PG was 90 kDa with a 26 kDa glycosaminoglycan chain, and the protein core of both PGs was 14.5 kDa. The two PGs carried sulfate groups mostly attached at C-4 of the 2-amino-2-deoxy-D-galactose units. The N-terminal amino acid sequence of both was similar to human bone PGII (decorin), normal and hypertrophic scar, and human dermal tissue PG. Topics: Amino Acid Sequence; Amino Acids; Biopolymers; Burns; Disaccharides; Electrophoresis, Cellulose Acetate; Electrophoresis, Polyacrylamide Gel; Glucuronates; Glucuronic Acid; Glycosaminoglycans; Humans; Iduronic Acid; Keloid; Molecular Sequence Data; Proteoglycans | 1990 |