idoxuridine has been researched along with Urinary Bladder Neoplasms in 18 studies
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The interactions of hydroxyurea (HU) and IdUrd were studied in a human bladder cancer cell line, 647V." | 7.69 | The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells. ( Kinsella, TJ; Kunugi, KA; Kuo, ML; Lindstrom, MJ, 1995) |
| " The interactions of hydroxyurea (HU) and IdUrd were studied in a human bladder cancer cell line, 647V." | 3.69 | The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells. ( Kinsella, TJ; Kunugi, KA; Kuo, ML; Lindstrom, MJ, 1995) |
| "5' Amino-5'-deoxythymidine (5'-AdThd) has been demonstrated previously to antagonize dTTP-mediated feedback inhibition of purified thymidine kinase from 647V, a human bladder cancer cell line." | 3.68 | Modulation of IdUrd-DNA incorporation and radiosensitization in human bladder carcinoma cells. ( Kinsella, TJ; Kunugi, KA; Miller, EM; Vazquez-Padua, MA, 1990) |
| "Iododeoxyuridine (IdUrd) potentiated the lethal but not the growth inhibitory properties of fluorouracil (FUra) and fluorodeoxyuridine (FdUrd) in human bladder cancer cells (T24)." | 3.67 | Modulation of 5-iodo-2'-deoxyuridine metabolism and cytotoxicity in human bladder cancer cells by fluoropyrimidines. ( Benson, AB; Cummings, KB; Fischer, PH; Trump, DL, 1985) |
| "Thymidine kinase is a key enzyme responsible for the activation of several anticancer and antiviral drugs." | 2.39 | Modulation of thymidine kinase activity: a biochemical strategy to enhance the activation of antineoplastic drugs. ( Vázquez-Padua, MA, 1994) |
| "In the analysis of the effects of radiation or drugs on clonogenic survival data of mammalian cells, it is often advantageous to compare entire dose-response curves generated under different experimental conditions rather than to conduct single-dose comparisons." | 1.29 | Global comparison of radiation and chemotherapy dose-response curves with a test for interaction. ( Kinsella, TJ; Kunugi, KA; Lindstrom, MJ, 1993) |
| "Since bladder cancer arises in the superficial lining of the urothelium, it is a likely candidate for site-directed administration of 5-iodo-2'-deoxyuridine radiolabeled with the Auger electron emitter 123I or 125I (*IUdR)." | 1.29 | Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer. ( Adelstein, SJ; Baranowska-Kortylewicz, J; Barclay, PD; Berman, RM; Kassis, AI; Richie, JP; Tutrone, RF; Van den Abbeele, AD, 1996) |
| "In patients with bladder cancer, little is known about diffusion in the tumor mass of 5-iodo-2'-deoxyuridine (IUdR) administered intraluminally, although previous studies based on external scanning have shown promising tumor-targeting properties of IUdR instilled intravesically." | 1.29 | Tumor uptake and mitotic activity pattern of 5-[125I]iodo-2'- deoxyuridine after intravesical infusion in patients with bladder cancer. ( Adelstein, SJ; Baldassarri, S; Baranowska-Kortylewicz, J; Buralli, S; Collecchi, P; Di Luca, L; Fontanini, G; Kassis, AI; Mariani, G, 1996) |
| " Toward this goal, we have performed preclinical and clinical studies, using various routes of administration, to detect adverse changes in normal tissues in both humans and animals." | 1.29 | Radiolabeled iododeoxyuridine: safety evaluation. ( Augustine, SC; Baranowska-Kortylewicz, J; Chiou, RK; Cohen, SM; Dalrymple, GV; Harrison, KA; Holdeman, KP; Leichner, PK; Lieberman, RP; Schneiderman, MH; Sharp, JG; Taylor, RJ; Tempero, MA, 1996) |
| "Sera of urinary bladder cancer patients reacted with nuclear antigens of the established cells." | 1.26 | Establishment and characterization of a new human urinary bladder carcinoma cell line (PS-1). ( Dagen, JE; Geder, L; Ladda, R; Laychock, AM; Rohner, TJ; Sanford, EJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawamura, H | 1 |
| Hashimoto, Y | 1 |
| Kunugi, KA | 6 |
| Lindstrom, MJ | 3 |
| Kinsella, TJ | 6 |
| Kuo, ML | 1 |
| Vázquez-Padua, MA | 4 |
| Chi, KH | 1 |
| Van den Abbeele, AD | 1 |
| Tutrone, RF | 1 |
| Berman, RM | 1 |
| Baranowska-Kortylewicz, J | 4 |
| Barclay, PD | 1 |
| Richie, JP | 1 |
| Adelstein, SJ | 3 |
| Kassis, AI | 3 |
| Mariani, G | 1 |
| Collecchi, P | 1 |
| Baldassarri, S | 1 |
| Di Luca, L | 1 |
| Buralli, S | 1 |
| Fontanini, G | 1 |
| Harrison, KA | 2 |
| Dalrymple, GV | 2 |
| Holdeman, KP | 2 |
| Schneiderman, MH | 2 |
| Lieberman, RP | 1 |
| Sharp, JG | 1 |
| Cohen, SM | 1 |
| Leichner, PK | 1 |
| Augustine, SC | 1 |
| Tempero, MA | 1 |
| Taylor, RJ | 2 |
| Chiou, RK | 2 |
| Sanford, EJ | 1 |
| Geder, L | 1 |
| Dagen, JE | 1 |
| Laychock, AM | 1 |
| Ladda, R | 1 |
| Rohner, TJ | 1 |
| Miller, EM | 2 |
| Benson, AB | 1 |
| Trump, DL | 1 |
| Cummings, KB | 1 |
| Fischer, PH | 2 |
| Begg, AC | 1 |
| Moonen, L | 1 |
| Hofland, I | 1 |
| Dessing, M | 1 |
| Bartelink, H | 1 |
| Reznikoff, CA | 1 |
| Ratschan, WJ | 1 |
| Lawson, AH | 1 |
| Riches, AC | 1 |
| Weaver, JP | 1 |
2 reviews available for idoxuridine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Modulation of thymidine kinase activity: a biochemical strategy to enhance the activation of antineoplastic drugs.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Biotransformation; Chlorocebus aethiops; DNA Damag | 1994 |
Preclinical animal studies with radioiododeoxyuridine.
Topics: Animals; Brain Neoplasms; Female; Gliosarcoma; Idoxuridine; Iodine Radioisotopes; Mice; Neoplasms, E | 1996 |
1 trial available for idoxuridine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Tumor localization and systemic absorption of intravesical instillation of radio-iodinated iododeoxyuridine in patients with bladder cancer.
Topics: Absorption; Administration, Intravesical; Aged; Female; Humans; Idoxuridine; Iodine Radioisotopes; M | 1999 |
15 other studies available for idoxuridine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Inhibitory effect of 5-halogenated deoxyuridines on in vitro keratinization of a transformed rat urinary bladder epithelial cell line.
Topics: Animals; Binding, Competitive; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; DNA Re | 1981 |
Effects of bleomycin with iododeoxyuridine, 5'-amino-5'-deoxythymidine, and radiation in a human bladder cancer cell line.
Topics: Bleomycin; Cell Survival; Combined Modality Therapy; Dideoxynucleosides; DNA Damage; Drug Synergism; | 1993 |
Global comparison of radiation and chemotherapy dose-response curves with a test for interaction.
Topics: Analysis of Variance; Bleomycin; Cell Survival; Combined Modality Therapy; Dose-Response Relationshi | 1993 |
The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells.
Topics: Cell Cycle; DNA, Neoplasm; Drug Interactions; Humans; Hydroxyurea; Idoxuridine; In Vitro Techniques; | 1995 |
Iododeoxyuridine chemosensitization of cis-diamminedichloroplatinum(II) in human bladder cancer cells.
Topics: Chromatography, High Pressure Liquid; Cisplatin; DNA, Neoplasm; Dose-Response Relationship, Drug; Hu | 1994 |
Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer.
Topics: Animals; Autoradiography; Carcinogens; Carcinoma, Transitional Cell; Female; Idoxuridine; Iodine Rad | 1996 |
Tumor uptake and mitotic activity pattern of 5-[125I]iodo-2'- deoxyuridine after intravesical infusion in patients with bladder cancer.
Topics: Administration, Intravesical; Aged; Humans; Idoxuridine; Iodine Radioisotopes; Male; Middle Aged; Mi | 1996 |
Radiolabeled iododeoxyuridine: safety evaluation.
Topics: Administration, Intravesical; Animals; Female; Humans; Idoxuridine; Injections, Intra-Arterial; Iodi | 1996 |
Establishment and characterization of a new human urinary bladder carcinoma cell line (PS-1).
Topics: Animals; Carcinoma, Transitional Cell; Cell Line; Chromosome Banding; Chromosomes, Human; Cytotoxici | 1978 |
Low pH does not affect the dose response for 5'-amino-5'-deoxythymidine modulation of IdUrd DNA incorporation and radiosensitization in a human bladder cancer cell line.
Topics: Cell Cycle; Cell Survival; Dideoxynucleosides; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose | 1992 |
Modulation of IdUrd-DNA incorporation and radiosensitization in human bladder carcinoma cells.
Topics: Carbon Radioisotopes; Cell Survival; Dideoxynucleosides; DNA, Neoplasm; Humans; Idoxuridine; Kinetic | 1990 |
Modulation of 5-iodo-2'-deoxyuridine metabolism and cytotoxicity in human bladder cancer cells by fluoropyrimidines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; DNA; Floxuridine; Fluorour | 1985 |
Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: intratumour sampling variations.
Topics: Antibodies, Monoclonal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Cycle; DNA, Neo | 1988 |
Preferential stimulation of iododeoxyuridine phosphorylation by 5'-aminothymidine in human bladder cancer cells in vitro.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Cycle; Drug Synergism; Epithelium; Human | 1986 |
Human bladder tumors in organ culture.
Topics: Carcinoma, Transitional Cell; Humans; Idoxuridine; Iodine Radioisotopes; Metaphase; Organ Culture Te | 1986 |