idoxuridine has been researched along with Neoplasms in 92 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Raltitrexed (Tomudex) is a specific inhibitor of thymidylate synthase with clinical activity in colorectal cancer." | 2.70 | Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd). ( Adjei, AA; Ames, MM; Atherton, P; Burch, P; Erlichman, C; Galanis, E; Goldberg, R; Pitot, H; Reid, J; Rubin, J; Safgren, SL; Sloan, J; Witzig, TE, 2001) |
| "To facilitate targeting to tumors, investigators have been examining the direct introduction of these agents into the targeted area or into an arterial blood supply that immediately precedes the target." | 2.39 | Radiolabeled nucleoside analogs in cancer diagnosis and therapy. ( Adelstein, SJ; Kassis, AI; Mariani, G, 1996) |
| "In the case of human tumors, which have in general rather long cell cycle times, this may require many days of continuous drug infusion to achieve adequate replacement of the DNA base thymidine with HP." | 2.38 | Radiobiology and clinical application of halogenated pyrimidine radiosensitizers. ( Cook, JA; Glatstein, E; Mitchell, JB; Russo, A; Straus, KL, 1989) |
| "Mathematical models of cancer relevant processes are being developed at an increasing rate." | 1.33 | On systems and control approaches to therapeutic gain. ( Jackson, RC; Loparo, KA; Radivoyevitch, T; Sedwick, WD, 2006) |
| " Continuous intraarterial infusion of IUdR was combined with irradiation to maximize drug concentration in tumor and reduce potential systemic toxicity." | 1.28 | Intraarterial iododeoxyuridine infusion combined with irradiation. A pilot study. ( Ansfield, FJ; Stephenson, JA; Vermund, H; Wiley, AL; Wirtanen, GW, 1990) |
| "Potential doubling times for the tumors were estimated to be 10 days." | 1.28 | Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies. ( Belanger, K; Chang, AE; Collins, JM; Cupp, JE; Kinsella, TJ; Klecker, RW; Rowland, J; Smith, R; Speth, PA, 1989) |
| " This method was applied to the study of the hormone-sensitivity of breast tumours, some of which showed a dose-response to 17 beta-estradiol." | 1.26 | Quantitative organ culture: an approach to prediction of tumour response. ( Krishnaswamy, A; Masters, JR; O'Donoghue, EP; Rigby, CC, 1980) |
| "No one in this group died from varicella or had evidence of visceral dissemination." | 1.25 | Varicella in children with cancer: Seventy-seven cases. ( Daniel, CB; Feldman, S; Hughes, WT, 1975) |
| "Subcutaneous tumors induced in newborn hamsters by type 12 adenovirus were suppressed when 0." | 1.24 | INHIBITION BY 5-IODODEOXYURIDINE OF THE ONCOGENIC EFFECTS OF ADENOVIRUS TYPE 12 IN HAMSTERS. ( CALABRESI, P; HUEBNER, RJ; LANE, WT; MCCOLLUM, RW; PRUSOFF, WH; WELCH, AD, 1963) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (71.74) | 18.7374 |
| 1990's | 14 (15.22) | 18.2507 |
| 2000's | 10 (10.87) | 29.6817 |
| 2010's | 2 (2.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherukupalli, S | 1 |
| Hampannavar, GA | 1 |
| Chinnam, S | 1 |
| Chandrasekaran, B | 1 |
| Sayyad, N | 1 |
| Kayamba, F | 1 |
| Reddy Aleti, R | 1 |
| Karpoormath, R | 1 |
| Kinsella, TJ | 9 |
| Collins, SP | 1 |
| Dritschilo, A | 1 |
| Kajstura, J | 1 |
| Urbanek, K | 1 |
| Perl, S | 1 |
| Hosoda, T | 1 |
| Zheng, H | 1 |
| Ogórek, B | 1 |
| Ferreira-Martins, J | 1 |
| Goichberg, P | 1 |
| Rondon-Clavo, C | 1 |
| Sanada, F | 1 |
| D'Amario, D | 1 |
| Rota, M | 1 |
| Del Monte, F | 1 |
| Orlic, D | 1 |
| Tisdale, J | 1 |
| Leri, A | 1 |
| Anversa, P | 1 |
| CALABRESI, P | 6 |
| CARDOSO, SS | 1 |
| FINCH, SC | 1 |
| KLIGERMAN, MM | 1 |
| VON ESSEN, CF | 1 |
| CHU, MY | 1 |
| WELCH, AD | 4 |
| HAMPTON, A | 1 |
| HAMPTON, EG | 1 |
| EIDINOFF, ML | 1 |
| PRUSOFF, WH | 8 |
| CREASEY, WA | 1 |
| MCCOLLUM, RW | 2 |
| HUEBNER, RJ | 1 |
| LANE, WT | 1 |
| CLIFTON, KH | 1 |
| SZYBALSKI, W | 1 |
| HEIDELBERGER, C | 2 |
| GOLLIN, FF | 2 |
| ANSFIELD, FJ | 3 |
| VERMUND, H | 3 |
| VLASINOVA, M | 1 |
| FISHBEIN, M | 1 |
| DELAMORE, IW | 1 |
| POTTS, AM | 1 |
| RAPP, F | 2 |
| MELNICK, JL | 2 |
| KITAHARA, T | 2 |
| OEHLERT, W | 1 |
| MAGNUSSON, B | 1 |
| FOX, BW | 1 |
| JOHNSON, RO | 1 |
| KISKEN, WA | 1 |
| CURRERI, AR | 1 |
| BUTEL, JS | 1 |
| FELDMAN, LA | 1 |
| FISCHER, GA | 1 |
| VONESSEN, CF | 1 |
| GRIESBACH, L | 1 |
| GHOBAR, A | 1 |
| MARK, JB | 1 |
| ROTENBERG, AD | 1 |
| BRUCE, WR | 1 |
| BAKER, RG | 1 |
| Choi, TH | 1 |
| Ahn, SH | 1 |
| Kwon, HC | 1 |
| Choi, CW | 1 |
| Awh, OD | 1 |
| Lim, SM | 1 |
| de Geus-Oei, LF | 1 |
| van Eerd-Vismale, J | 1 |
| Molthoff, C | 1 |
| Corstens, F | 1 |
| Oyen, W | 1 |
| Boerman, O | 1 |
| Janssen, HL | 1 |
| Ljungkvist, AS | 1 |
| Rijken, PF | 1 |
| Sprong, D | 1 |
| Bussink, J | 1 |
| van der Kogel, AJ | 1 |
| Haustermans, KM | 1 |
| Begg, AC | 1 |
| Radivoyevitch, T | 1 |
| Loparo, KA | 1 |
| Jackson, RC | 1 |
| Sedwick, WD | 1 |
| White, DO | 1 |
| Mitchell, JB | 4 |
| Russo, A | 3 |
| Morstyn, G | 1 |
| Glatstein, E | 3 |
| Bloomer, WD | 3 |
| McLaughlin, WH | 2 |
| Adelstein, SJ | 5 |
| Wolf, AP | 1 |
| Fairchild, RG | 1 |
| Bond, VP | 1 |
| Curphey, TJ | 1 |
| Masters, JR | 1 |
| Krishnaswamy, A | 1 |
| Rigby, CC | 1 |
| O'Donoghue, EP | 1 |
| Holmes, JM | 1 |
| Brun Ugstad, M | 1 |
| Hofer, KG | 1 |
| Busk, CM | 1 |
| Earl, HM | 1 |
| Wrigley, PF | 1 |
| Lister, TA | 1 |
| Schilsky, RL | 1 |
| Janisch, L | 1 |
| Berezin, F | 1 |
| Mick, R | 1 |
| Vogelzang, NJ | 1 |
| Ratain, MJ | 1 |
| Ritter, MA | 1 |
| Fowler, JF | 1 |
| Kim, YJ | 1 |
| Gilchrist, KW | 1 |
| Morrissey, LW | 1 |
| Philip, PA | 2 |
| Kaklamanis, L | 1 |
| Carmichael, J | 1 |
| Tonkin, K | 1 |
| Morrison, H | 1 |
| Gatter, K | 1 |
| Harris, AL | 1 |
| O'Donoghue, JA | 1 |
| Kassis, AI | 2 |
| Mariani, G | 2 |
| Baranowska-Kortylewicz, J | 2 |
| Kortylewicz, ZP | 1 |
| Hoffman, D | 1 |
| Dalrymple, GV | 1 |
| Vignaud, JM | 1 |
| Duprez, A | 1 |
| Rew, DA | 1 |
| Mach, RH | 1 |
| Huang, Y | 1 |
| Buchheimer, N | 1 |
| Kuhner, R | 1 |
| Wu, L | 1 |
| Morton, TE | 1 |
| Wang, L | 1 |
| Ehrenkaufer, RL | 1 |
| Wallen, CA | 1 |
| Wheeler, KT | 1 |
| Galanis, E | 1 |
| Goldberg, R | 1 |
| Reid, J | 1 |
| Atherton, P | 1 |
| Sloan, J | 1 |
| Pitot, H | 1 |
| Rubin, J | 1 |
| Adjei, AA | 1 |
| Burch, P | 1 |
| Safgren, SL | 1 |
| Witzig, TE | 1 |
| Ames, MM | 1 |
| Erlichman, C | 1 |
| Berry, SE | 1 |
| Smellie, SG | 1 |
| Parsons, PG | 1 |
| Manteuil-Brutlag, S | 1 |
| Fresen, KO | 1 |
| zur Hausen, H | 1 |
| Chen, MS | 1 |
| Fischer, PH | 1 |
| Lin, TS | 1 |
| Shiau, GT | 1 |
| Schinazi, RF | 1 |
| Kaplan, HS | 1 |
| Birchall, JP | 1 |
| Owen, JJ | 1 |
| Kim, T | 1 |
| Song, CW | 1 |
| Levitt, SH | 1 |
| Volm, M | 1 |
| Gerick, D | 1 |
| Schuhmacher, J | 1 |
| Wayss, K | 1 |
| Feldman, S | 2 |
| Hughes, WT | 2 |
| Daniel, CB | 1 |
| Cooper, EH | 1 |
| Bedford, AJ | 1 |
| Kenny, TE | 1 |
| Miller, MA | 2 |
| Bokhari, SA | 1 |
| Qadir, K | 1 |
| Raza, A | 2 |
| Bagshawe, KD | 2 |
| Searle, F | 1 |
| Green, AJ | 1 |
| Begent, RH | 1 |
| Newlands, ES | 1 |
| Rustin, GJ | 1 |
| Adam, T | 1 |
| Mazewski, C | 1 |
| Sheikh, Y | 1 |
| Lampkin, B | 1 |
| Sawaya, R | 1 |
| Crone, K | 1 |
| Berger, T | 1 |
| Reising, J | 1 |
| Gray, J | 1 |
| van den Abbeele, AD | 1 |
| Ito, S | 1 |
| Cheson, BD | 1 |
| Wirtanen, GW | 1 |
| Wiley, AL | 1 |
| Stephenson, JA | 1 |
| Cook, JA | 1 |
| Straus, KL | 1 |
| Coleman, CN | 1 |
| Speth, PA | 2 |
| Chang, AE | 1 |
| Klecker, RW | 3 |
| Belanger, K | 2 |
| Smith, R | 2 |
| Rowland, J | 1 |
| Cupp, JE | 1 |
| Collins, JM | 3 |
| Humm, JL | 1 |
| Charlton, DE | 1 |
| Rowland, JB | 1 |
| Miller, RW | 1 |
| DeGraff, W | 1 |
| Jenkins, JF | 1 |
| Fine, RL | 1 |
| Strong, JM | 1 |
| Shearer, WT | 2 |
| Philpott, GW | 2 |
| Parker, CW | 2 |
| Hirsch, MS | 2 |
| Black, PH | 1 |
| Goffinet, DR | 1 |
| Bagshaw, MA | 1 |
| Oldham, RK | 1 |
| Siwarski, D | 1 |
| McCoy, JL | 1 |
| Plata, EJ | 1 |
| Herberman, RB | 1 |
| Kim, HY | 1 |
| Porteous, DD | 1 |
| Suit, HD | 1 |
19 reviews available for idoxuridine and Neoplasms
| Article | Year |
|---|---|
An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold.
Topics: Adenosine; Anti-Infective Agents; Antineoplastic Agents; Cytokinins; Enzyme Inhibitors; Humans; Mole | 2018 |
Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers.
Topics: DNA Damage; DNA Mismatch Repair; DNA Repair; Drug Resistance, Neoplasm; Genes, BRCA1; Genes, BRCA2; | 2009 |
A REVIEW OF SOME ASPECTS OF 5-IODODEOXYURIDINE AND AZAURIDINE.
Topics: Azauridine; Idoxuridine; Metabolism; Neoplasms; Nucleosides; Pharmacology | 1963 |
CURRENT STATUS OF CLINICAL INVESTIGATIONS WITH 6-AZAURIDINE, 5-IODO-2'-DEOXYURIDINE, AND RELATED DERIVATIVES.
Topics: Antineoplastic Agents; Azauridine; Humans; Idoxuridine; Neoplasms; Nucleosides | 1963 |
Antiviral chemotherapy.
Topics: Acyclovir; Amantadine; Animals; Antiviral Agents; Bromodeoxyuridine; Female; Hepatitis B; Herpes Gen | 1984 |
Therapeutic applications of Auger and alpha emitting radionuclides.
Topics: Alpha Particles; Animals; Astatine; Cricetinae; Electrons; Humans; Idoxuridine; Iodine Radioisotopes | 1984 |
Radiolabeled nucleoside analogs in cancer diagnosis and therapy.
Topics: Animals; Humans; Idoxuridine; Iodine Radioisotopes; Neoplasms; Radionuclide Imaging; Tumor Cells, Cu | 1996 |
Prodrugs in site-selective delivery of radiopharmaceuticals.
Topics: Animals; Humans; Idoxuridine; Iodine Radioisotopes; Neoplasms; Prodrugs; Radionuclide Imaging; Radio | 1997 |
Targeting DNA mismatch repair for radiosensitization.
Topics: Antineoplastic Agents; Apoptosis; Base Pair Mismatch; Bromodeoxyuridine; Cell Cycle; Combined Modali | 2001 |
[The "sarc" gene].
Topics: Alpharetrovirus; Animals; Base Sequence; Birds; Bromodeoxyuridine; Cell Transformation, Neoplastic; | 1975 |
5-(125I)-iododeoxyuridine and the Auger effect: biological consequences and implications for therapy.
Topics: Animals; Cell Line; Cell Survival; DNA; Electrons; Energy Transfer; Idoxuridine; Iodine Radioisotope | 1978 |
1977 Henry H. Janeway lecture: fundamental mechanisms in combined modality therapy of cancer.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Dactinomycin; DNA Repair; DNA, Neoplasm; Electron | 1977 |
Cell death in normal and malignant tissues.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Autolysis; Cell Differentiation; Cell Division; Cel | 1975 |
Potential for tumor therapy with iodine-125 labeled immunoglobulins.
Topics: Humans; Idoxuridine; Immunoglobulins; Immunotherapy; Iodine Radioisotopes; Neoplasms | 1991 |
Radiobiology and clinical application of halogenated pyrimidine radiosensitizers.
Topics: Bromodeoxyuridine; Combined Modality Therapy; Humans; Idoxuridine; Neoplasms; Radiation-Sensitizing | 1989 |
Modification of radiotherapy by radiosensitizers and cancer chemotherapy agents. I. Radiosensitizers.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Combined Modality Therapy; Glutathione; Humans; Idoxuridin | 1989 |
The use of non-hypoxic cell sensitizers in radiobiology and radiotherapy.
Topics: Animals; Bromodeoxyuridine; Buthionine Sulfoximine; Cell Survival; Cricetinae; Diamide; DNA Repair; | 1986 |
Activation of mammalian leukemia viruses.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Carcinogens; Cats; Cattle; Cell Transformation, Neoplas | 1974 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromoura | 1974 |
3 trials available for idoxuridine and Neoplasms
| Article | Year |
|---|---|
The use of halogenated thymidine analogs as clinical radiosensitizers: rationale, current status, and future prospects: non-hypoxic cell sensitizers.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Survival; Clinical Trials as Topic; Combined Modal | 1984 |
Phase I clinical and pharmacological study of iododeoxyuridine and bleomycin in patients with advanced cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Female; Humans; | 1993 |
Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap | 2001 |
70 other studies available for idoxuridine and Neoplasms
| Article | Year |
|---|---|
The mismatch repair and base excision repair pathways: an opportunity for individualized (personalized) sensitization of cancer therapy.
Topics: Base Pair Mismatch; DNA Repair; Endodeoxyribonucleases; Humans; Idoxuridine; Neoplasms; Thymine DNA | 2009 |
Cardiomyogenesis in the adult human heart.
Topics: Adult; Age Factors; Aged; Animals; Autopsy; Cell Death; Cell Fusion; Cell Nucleus; Cell Proliferatio | 2010 |
Initial clinical studies with 5-iodo-2'-deoxyuridine.
Topics: Biomedical Research; Idoxuridine; Neoplasms; Nucleosides; Nucleotides | 1961 |
Nucleotides. III. Synthesis and effects with cells in culture of 131-I-labeled 5-iodo-2'-deoxyuridine-5'-phosphate.
Topics: Biochemical Phenomena; Deoxyuridine; Idoxuridine; Neoplasms; Nucleosides; Nucleotides; Phosphates; T | 1962 |
RECENT STUDIES WITH 5-IODODEOXYURIDINE (IUDR) AND RELATED COMPOUNDS.
Topics: Idoxuridine; Neoplasms; Pharmacology; Research | 1963 |
INHIBITION BY 5-IODODEOXYURIDINE OF THE ONCOGENIC EFFECTS OF ADENOVIRUS TYPE 12 IN HAMSTERS.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antineoplastic Agents; Carcinogens; Cricetinae; Huma | 1963 |
SUMMARY OF INFORMAL DISCUSSIONS ON THE ROLE OF PYRIMIDINE ANTAGONISTS FOLLOWING PAPERS BY DR. PRUSOFF AND DR. CALABRESI.
Topics: Antimetabolites; Antineoplastic Agents; Floxuridine; Fluorouracil; Idoxuridine; Neoplasms; Nucleosid | 1963 |
INCORPORATION OF I-125-LABELED IODODEOXYURIDINE INTO THE DEOXYRIBONUCLEIC ACID OF MURINE AND HUMAN TISSUES FOLLOWING THERAPEUTIC DOSES.
Topics: Adenocarcinoma; Animals; DNA; DNA, Neoplasm; Floxuridine; Geriatrics; Idoxuridine; Intestine, Small; | 1963 |
RADIATION-INDUCED GIANT CELLS. THE EFFECT OF HALOGENATED THYMIDINE ANALOGUES AND AET.
Topics: beta-Aminoethyl Isothiourea; Giant Cell Tumors; Giant Cells; Idoxuridine; Neoplasms; Neoplasms, Radi | 1963 |
MEDICAL PROGRESS IN 1963.
Topics: Antihypertensive Agents; Contraceptive Agents; Contraceptives, Oral; Coronary Disease; Education, Me | 1964 |
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE.
Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimen | 1964 |
TRACER STUDIES ON A TRANSPLANTABLE HAMSTER MELANOMA.
Topics: Animals; Chlorpromazine; Cricetinae; Eye Neoplasms; Fluoresceins; Idoxuridine; Iodine Isotopes; Mela | 1964 |
[TREATMENT OF INOPERABLE BRONCHIAL CANCER WITH A COMBINATION OF CHEMOTHERAPY AND IRRADIATION].
Topics: Bronchial Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Fluorouracil; Humans; Idoxuridine; L | 1964 |
TUMOR AND VIRUS ANTIGENS OF SIMIAN VIRUS 40: DIFFERENTIAL INHIBITION OF SYNTHESIS BY CYTOSINE ARABINOSIDE.
Topics: Antigens; Antigens, Viral; Cytarabine; Cytosine; Humans; Idoxuridine; Metabolism; Neoplasms; Nucleos | 1965 |
[AUTORADIOGRAPHIC STUDIES ON THE INCORPORATION OF 5-IODO-2-DESOXYURIDINE (IUDR) INTO THE DNA OF CELLS OF YOSHIDA HEPATOMA AH 130].
Topics: Autoradiography; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Idoxuridine; Liver Neoplasms; Neopla | 1965 |
THE COMPARATIVE UPTAKE OF I-125-LABELED 5-IODO-2'-DEOXYURIDINE AND THYMIDINE-H3 INTO TISSUES OF MICE BEARING HEPATOMA-129.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Histocytochemistry; Idoxuridine; Inte | 1965 |
SQUAMOUS CELL CARCINOMA OF ORAL CAVITY; INTRA-ARTERIAL INFUSION WITH FLUOROURACIL AND IDOXURIDINE.
Topics: Carcinoma; Carcinoma, Squamous Cell; Drug Therapy; Fluorouracil; Humans; Idoxuridine; Infusions, Int | 1965 |
DIFFERENTIAL EFFECTS OF INHIBITORS ON THE STEPS LEADING TO THE FORMATION OF SV40 TUMOR AND VIRUS ANTIGENS.
Topics: Animals; Antigens; Antigens, Viral; Antimetabolites; Chlorocebus aethiops; Complement Fixation Tests | 1965 |
THE COMPARISON OF RADIATION AND ANTIMETABOLITE RESPONSES OF GENETICALLY ALTERED MURINE LEUKEMIC CELLS.
Topics: Animals; Antimetabolites; Chromosomes; Floxuridine; Genetics; Idoxuridine; Leukemia; Leukemia, Exper | 1965 |
The potentiation by 5-iodo-2'-deoxyuridine (IUDR) of the tumor-inhibitory activity of 5-fluoro-2'-deoxyuridine (FUDR).
Topics: Antineoplastic Agents; Deoxyuridine; Floxuridine; Humans; Idoxuridine; Neoplasms; Nucleosides; Nucle | 1960 |
Studies on the mechanism of action of 5-iododeoxyuridine, an analog of thymidine.
Topics: Idoxuridine; Neoplasms; Nucleosides; Nucleotides; Organic Chemicals; Thymidine | 1960 |
Incorporation of iododeoxyuridine into the deoxyribonucleic acid of mouse Ehrlich-ascites-tumor cells in vivo.
Topics: Animals; Ascites; Biochemical Phenomena; DNA; Idoxuridine; Mice; Neoplasms; Nucleosides; Nucleotides | 1960 |
Regional protection in cancer chemotherapy. II. Preliminary studies with hypogastric artery infusion of thymidine during treatment with 5-iodo-2'-deoxyuridine.
Topics: Antineoplastic Agents; Aorta, Abdominal; Idoxuridine; Infusions, Intra-Arterial; Infusions, Parenter | 1962 |
Incorporation of 5-iododeoxyuridine 1311 in spontaneous C3H mouse mammary tumours.
Topics: Animals; Breast Neoplasms; Humans; Idoxuridine; Iodine; Iodine Radioisotopes; Mice; Mice, Inbred C3H | 1962 |
In vivo comparison of IVDU and IVFRU in HSV1-TK gene expressing tumor bearing rats.
Topics: Animals; Cell Line, Tumor; Drug Monitoring; Drug Stability; Floxuridine; Genetic Therapy; Herpesviru | 2004 |
Tracers to monitor the response to chemotherapy: in vitro screening of four radiopharmaceuticals.
Topics: DNA; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorodeoxyglucose F18; Huma | 2004 |
Thymidine analogues to assess microperfusion in human tumors.
Topics: Animals; Benzimidazoles; Bromodeoxyuridine; Fluorescent Dyes; Humans; Idoxuridine; Mice; Mice, Inbre | 2005 |
On systems and control approaches to therapeutic gain.
Topics: Antineoplastic Agents; Core Binding Factor Alpha 2 Subunit; DNA Repair; DNA, Neoplasm; Drug Resistan | 2006 |
Photon activation therapy.
Topics: Animals; Combined Modality Therapy; Cricetinae; Electrons; Humans; Idoxuridine; Mice; Neoplasms; Rad | 1984 |
Correspondence re: J. M. Yuhas and A. P. Li. Growth fraction as the major determinant of multicellular tumor spheroid growth rates. Cancer Res., 38: 1528-1532, 1978.
Topics: Animals; Idoxuridine; Mathematics; Mice; Models, Biological; Neoplasms | 1984 |
Quantitative organ culture: an approach to prediction of tumour response.
Topics: Breast Neoplasms; DNA, Neoplasm; Dose-Response Relationship, Drug; Estradiol; Female; Humans; Idoxur | 1980 |
Therapeutic implications of iodine-125 cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Humans; Idoxuridine; Intercalating Agents | 1982 |
Measurement of the cell loss from two spontaneous canine tumours.
Topics: Animals; Cell Division; Cell Survival; Dog Diseases; Dogs; Female; Idoxuridine; Male; Neoplasms | 1982 |
[Cancer development after idoxuridine therapy?].
Topics: Humans; Idoxuridine; Neoplasms | 1982 |
Radiation biology and potential therapeutic applications of radionuclides.
Topics: Animals; Antibodies, Neoplasm; Astatine; Cricetinae; Gallium Radioisotopes; Humans; Idoxuridine; Iod | 1980 |
Triple drug therapy of Herpes zoster infection occurring in patients with reticulo-endothelial neoplasia--a preliminary study.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Herpes Zoster; Hodgkin Disease; Humans; Idoxuridine; | 1980 |
Tumor cell kinetics using two labels and flow cytometry.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Cycle; DNA, Neoplasm; Female; Flow Cytometr | 1994 |
The influence of high dose hydroxyurea on the incorporation of 5-iodo-2-deoxyuridine (IUdR) by human bone marrow and tumour cells in vivo.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Biopsy, | 1993 |
Radiolabeled IUdR. Proceedings of a meeting. Boston, Massachusetts, October 4, 1994.
Topics: Animals; Antimetabolites; Humans; Idoxuridine; Iodine Radioisotopes; Neoplasms | 1996 |
Strategies for selective targeting of Auger electron emitters to tumor cells.
Topics: Electrons; Genes, myc; Humans; Idoxuridine; Iodine Radioisotopes; Neoplasms; Oligonucleotides | 1996 |
[Cell division: practical approach].
Topics: Bromodeoxyuridine; Cell Division; Humans; Idoxuridine; Immunohistochemistry; Ki-67 Antigen; Neoplasm | 1997 |
Laser cytometry of human tissues and tumors: proliferation and therapeutic applications.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Bromodeoxyuridine; Cell Division; Flow Cytometry; Humans; | 2001 |
[[(18)F]N-(4'-fluorobenzyl)-4-(3-bromophenyl) acetamide for imaging the sigma receptor status of tumors: comparison with [(18)F]FDG, and [(125)I]IUDR.
Topics: Acetamides; Adenocarcinoma; Animals; Female; Fluorodeoxyglucose F18; Idoxuridine; Mammary Neoplasms, | 2001 |
Effects of thymidine analogues on murine and human cells.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Line; Deoxyuridine; Fibroblasts; Floxuridine; Humans; I | 1979 |
Transient induction of a nuclear antigen unrelated to Epstein-Barr nuclear antigen in cells of two human B-lymphoma lines converted by Epstein-Barr virus.
Topics: Aminopterin; Antigens, Neoplasm; Antigens, Viral; Burkitt Lymphoma; Cell Line; Cell Nucleus; Herpesv | 1977 |
Role of nucleosides in virus and cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Drug Evaluation, Preclinical; Herpesviridae Infect | 1979 |
An [125I]iododesoxyuridine utilization assay to measure the survival of human cells after various freezing programs.
Topics: Cell Survival; Colonic Neoplasms; DNA; Female; Freezing; Humans; Idoxuridine; Neoplasms; Ovarian Neo | 1979 |
Effect of irradiation on immune cell-mediated cytolysis of tumour cells.
Topics: Animals; Idoxuridine; Immunity, Cellular; Iodine Radioisotopes; Lymphocytes; Male; Mast-Cell Sarcoma | 1975 |
Enhancement of incorporation of 131iododeoxyuridine into tumors after application of Clostridium oncolyticum s. butyricum (M 55). Animal experiments on positive scintigraphic localization of tumors.
Topics: Animals; Carcinoma; Clostridium; Cricetinae; Idoxuridine; Image Enhancement; Iodine Radioisotopes; M | 1977 |
Varicella in children with cancer: Seventy-seven cases.
Topics: Chickenpox; Child; Complement Fixation Tests; Encephalitis; Hepatitis; Humans; Idoxuridine; Immuniza | 1975 |
Simultaneous assessment of TGFB and cell cycle kinetics using IUdR/BrdU infusions in human neoplasms from plastic-embedded tissue.
Topics: Antibodies, Monoclonal; Biopsy; Bone Marrow; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Coloni | 1992 |
In vivo uptake of 131I-5-iodo-2-deoxyuridine by malignant tumours in man.
Topics: Administration, Oral; Adult; Aged; Deoxyuridine; DNA; Female; Gamma Cameras; Humans; Hydroxyurea; Id | 1991 |
Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine.
Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Nucleus; DNA Replication; Gastroint | 1991 |
Clinical trials referral resource.
Topics: Antibodies, Monoclonal; Clinical Trials as Topic; Humans; Idoxuridine; Leukemia, Lymphocytic, Chroni | 1990 |
Intraarterial iododeoxyuridine infusion combined with irradiation. A pilot study.
Topics: Adolescent; Adult; Catheterization, Peripheral; Female; Follow-Up Studies; Humans; Idoxuridine; Infu | 1990 |
Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies.
Topics: Cell Cycle; Combined Modality Therapy; DNA; DNA, Neoplasm; Granulocytes; Humans; Idoxuridine; Infusi | 1989 |
A new calculational method to assess the therapeutic potential of Auger electron emission.
Topics: DNA, Neoplasm; DNA, Single-Stranded; Electrons; Idoxuridine; Iodine Radioisotopes; Neoplasms; Radioa | 1989 |
Reversed-role chemotherapy for resistant cancer.
Topics: Animals; Antineoplastic Agents; Autoradiography; DNA; DNA, Neoplasm; Drug Evaluation; Drug Resistanc | 1986 |
Fluorodeoxyuridine modulation of the incorporation of iododeoxyuridine into DNA of granulocytes: a phase I and clinical pharmacological study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; DNA; Female; Floxuridine; Granulocytes; | 1988 |
Photon activation therapy (PAT)
Topics: Combined Modality Therapy; Humans; Idoxuridine; Neoplasms; Radiation-Sensitizing Agents | 1987 |
Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation.
Topics: Chromatography, High Pressure Liquid; Deoxyuridine; Humans; Idoxuridine; Infusions, Parenteral; Neop | 1985 |
Stimulation of cells by antibody.
Topics: Animals; Antibodies, Neoplasm; Carcinoma; Cell Line; Colonic Neoplasms; Cross Reactions; DNA, Neopla | 1973 |
Immunological activation of oncogenic viruses: interrelationship of immunostimulation and immunosuppression.
Topics: Animals; Antibody Formation; Antilymphocyte Serum; Graft Rejection; Graft vs Host Reaction; Humans; | 1974 |
Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Antimetabolites; Cytarabine; Female; Floxuridine; Gangrene; He | 1965 |
Evaluation of a cell-mediated cytotoxicity assay utilizing 125 iododeoxyuridine-labeled tissue-culture target cells.
Topics: Adult; AKR murine leukemia virus; Animals; Antigens, Neoplasm; Breast Neoplasms; Cell Line; Cells, C | 1973 |
[Herpes simplex virus and its infections].
Topics: Cytarabine; Eczema; Female; Gingivitis; Herpes Simplex; Herpesviridae; Humans; Idoxuridine; Infant, | 1973 |
Herpes zoster in children with cancer.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Cobalt Isotopes; Cytarabine; Herpes Zoste | 1973 |
Humoral immunostimulation. I. Increased uptake of (125I)iododeoxyuridine and (3H)thymidine into TNP-cells treated with anti-TNP antibody.
Topics: Animals; Antibodies; Carcinoma; Cell Line; Female; Glucose Oxidase; HeLa Cells; Humans; Idoxuridine; | 1974 |
The toxicity of 125 IUdR in cultured mouse BP8 tumour cells.
Topics: Animals; Cell Line; Cell Nucleus; Cell Survival; DNA, Neoplasm; Idoxuridine; Iodine Isotopes; Mice; | 1971 |
Theoretical evaluation of a limitation in the use of pyrimidine analogs in radiation therapy.
Topics: Bromodeoxyuridine; Culture Techniques; Deoxyuridine; Idoxuridine; Neoplasms; Neoplasms, Experimental | 1966 |