idoxuridine has been researched along with Malignant Melanoma in 39 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The modelling technique was applied to fourteen uveal melanomas from patients who received in vivo injections of two thymidine analogues, bromodeoxyuridine (BrdUrd) and iododeoxyuridine (IdUrd)." | 3.69 | A stochastic model for dual label experiments: an analysis of the heterogeneity of S phase duration. ( Char, D; Kaleta-Michaels, S; Kroll, S, 1995) |
| "Tertiary amine local anesthetics, such as dibucaine and tetracaine, have been found to reversibly modify the blood-borne implantation and experimental metastatic properties of B16 melanoma cells in syngeneic C57BL/6 mice." | 3.67 | Effects of tertiary amine local anesthetics on the blood-borne implantation and cell surface properties of metastatic mouse melanoma cells. ( Fidler, IJ; Nicolson, GL; Poste, G, 1986) |
| " FUdR was found to be chemically toxic in itself to 2 canine tissue culture lines at doses used in the literature to increase 125IUdR uptake." | 1.27 | The toxicity of fluorodeoxyuridine when used to increase the uptake of 125I-iododeoxyuridine into tissue culture cells in vitro. ( Holmes, JM, 1983) |
| " Saline or diphtheria toxin (DT), which is selectively toxic to human cells compared to those of mice, was injected, and the loss of 125I from the animals was monitored daily with a whole-body gamma scintillation detector." | 1.27 | Correlation of cytotoxicity with elimination of iodine-125 from nude mice inoculated with prelabeled human melanoma cells. ( Giovanella, BC; Lockshin, A; Mendoza, JT; Quian, C; Stehlin, JS; Vardeman, DM, 1984) |
| " Administration of different amounts of IL-2 in vivo to 2 patients with melanoma revealed that the initial level of IL-2 in the circulation was related to the dose given and had a half-life of approximately 22." | 1.27 | Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjects. ( Bindon, C; Czerniecki, M; Edwards, A; Harris, R; Hersey, P; McCarthy, WH; Ruell, P, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (76.92) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| André, M | 1 |
| Tarrit, S | 2 |
| Couret, MJ | 1 |
| Galmier, MJ | 1 |
| Débiton, E | 1 |
| Chezal, JM | 3 |
| Mounetou, E | 1 |
| El Aissi, R | 2 |
| Chavignon, O | 2 |
| Moreau, E | 2 |
| Miladi, I | 1 |
| Miot-Noirault, E | 1 |
| POTTS, AM | 1 |
| Semnani, ES | 1 |
| Wang, K | 1 |
| Adelstein, SJ | 1 |
| Kassis, AI | 1 |
| Holmes, JM | 1 |
| Lockshin, A | 2 |
| Giovanella, BC | 2 |
| Quian, C | 2 |
| Mendoza, JT | 2 |
| Vardeman, DM | 2 |
| Stehlin, JS | 2 |
| Bindon, C | 1 |
| Czerniecki, M | 1 |
| Ruell, P | 1 |
| Edwards, A | 1 |
| McCarthy, WH | 1 |
| Harris, R | 1 |
| Hersey, P | 1 |
| Kroll, S | 1 |
| Char, D | 1 |
| Kaleta-Michaels, S | 1 |
| Philip, PA | 1 |
| Kaklamanis, L | 1 |
| Carmichael, J | 1 |
| Tonkin, K | 1 |
| Morrison, H | 1 |
| Gatter, K | 1 |
| Harris, AL | 1 |
| Larsen, RH | 1 |
| Vaidyanathan, G | 1 |
| Zalutsky, MR | 1 |
| Dutta, SK | 1 |
| Gorgacz, EJ | 1 |
| Albert, TF | 1 |
| Ingling, AL | 1 |
| Van Tieghem, N | 1 |
| Doyen, A | 1 |
| Liteanu, D | 1 |
| Cogniaux, J | 1 |
| Frühling, J | 1 |
| Fritze, D | 1 |
| Kern, DH | 1 |
| Drogemuller, CR | 1 |
| Pilch, YH | 1 |
| Gericke, D | 1 |
| Levy, JA | 1 |
| Rutledge, F | 1 |
| Dimpfl, J | 1 |
| Silagi, S | 1 |
| Kaufman, ER | 1 |
| Davidson, RL | 1 |
| Hart, IR | 1 |
| Fidler, IF | 1 |
| Volm, M | 1 |
| Gerick, D | 1 |
| Schuhmacher, J | 1 |
| Wayss, K | 1 |
| Klucis, E | 1 |
| Jackson, L | 1 |
| Parsons, PG | 1 |
| Fidler, IJ | 7 |
| Norbury, KC | 1 |
| Kidson, SH | 1 |
| De Haan, JB | 1 |
| Giavazzi, R | 1 |
| Garofalo, A | 1 |
| Bani, MR | 1 |
| Abbate, M | 1 |
| Ghezzi, P | 1 |
| Boraschi, D | 1 |
| Mantovani, A | 1 |
| Dejana, E | 1 |
| Okubo, A | 1 |
| Sone, S | 1 |
| Tanaka, M | 1 |
| Ogura, T | 1 |
| Nicolson, GL | 1 |
| Poste, G | 1 |
| Price, JE | 1 |
| Aukerman, SL | 1 |
| Riabukhin, IuS | 2 |
| Sevast'ianov, AI | 2 |
| Spryshkova, RA | 2 |
| Naĭdenov, MG | 1 |
| Serebriakov, NG | 1 |
| Kozielski, T | 1 |
| Johnson, FD | 1 |
| Jacobs, EM | 1 |
| Kreider, JW | 2 |
| Flickinger, JT | 1 |
| Lengle, N | 2 |
| Shoff, W | 1 |
| Zeidman, I | 2 |
| Levy, NL | 1 |
| Epstein, WL | 1 |
| Fukuyama, K | 1 |
| Drake, TE | 1 |
| Shoff, WH | 1 |
39 other studies available for idoxuridine and Malignant Melanoma
| Article | Year |
|---|---|
Spacer optimization of new conjugates for a melanoma-selective delivery approach.
Topics: Acetals; Antineoplastic Agents; Cells, Cultured; Drug Delivery Systems; Drug Stability; Humans; Idox | 2013 |
Melanoma-targeted delivery system (part 1): design, synthesis and evaluation of releasable disulfide drug by glutathione.
Topics: Antineoplastic Agents; Disulfides; Drug Delivery Systems; Drug Design; Drug Liberation; Glutathione; | 2015 |
Melanoma-targeted delivery system (part 2): Synthesis, radioiodination and biological evaluation in B16F0 bearing mice.
Topics: Animals; Humans; Idoxuridine; Iodine Radioisotopes; Melanoma; Mice; Prodrugs; Radiopharmaceuticals; | 2016 |
TRACER STUDIES ON A TRANSPLANTABLE HAMSTER MELANOMA.
Topics: Animals; Chlorpromazine; Cricetinae; Eye Neoplasms; Fluoresceins; Idoxuridine; Iodine Isotopes; Mela | 1964 |
5-[123I/125I]iodo-2'-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting.
Topics: Animals; Drug Delivery Systems; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Lung Neoplasms; | 2005 |
The toxicity of fluorodeoxyuridine when used to increase the uptake of 125I-iododeoxyuridine into tissue culture cells in vitro.
Topics: Animals; Cell Line; Cells; Culture Techniques; Dogs; Floxuridine; Idoxuridine; Iodine Radioisotopes; | 1983 |
Correlation of cytotoxicity with elimination of iodine-125 from nude mice inoculated with prelabeled human melanoma cells.
Topics: Animals; Cell Survival; Diphtheria Toxin; Humans; Idoxuridine; Iodine Radioisotopes; Kinetics; Melan | 1984 |
Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjects.
Topics: Adult; Electrophoresis, Polyacrylamide Gel; Humans; Idoxuridine; Immunotherapy; Injections, Intraven | 1983 |
A stochastic model for dual label experiments: an analysis of the heterogeneity of S phase duration.
Topics: Biomarkers; Bromodeoxyuridine; Choroid Neoplasms; Humans; Idoxuridine; Melanoma; S Phase; Stochastic | 1995 |
The influence of high dose hydroxyurea on the incorporation of 5-iodo-2-deoxyuridine (IUdR) by human bone marrow and tumour cells in vivo.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Biopsy, | 1993 |
Cytotoxicity of alpha-particle-emitting 5-[211At]astato-2'-deoxyuridine in human cancer cells.
Topics: Alpha Particles; Antineoplastic Agents; Astatine; DNA, Neoplasm; Glioma; Humans; Idoxuridine; Iodine | 1997 |
Isolation of a herpesvirus from the cell culture of a malignant melanoma of a ground squirrel (Spermophilus tridecemlineatus).
Topics: Animals; Cells, Cultured; Chloroform; Cytopathogenic Effect, Viral; Herpesviridae; Idoxuridine; Male | 1977 |
Modulation of tyrosinase activity and viral information by 5-iodo-deoxyuridine and L-dopa in a human melanoma cell line [proceedings].
Topics: Animals; Antigens, Viral; Catechol Oxidase; Cell Line; Humans; Idoxuridine; Levodopa; Magnesium; Mel | 1979 |
A new micromethod for the detection of HL-A antigens on cultured human tumor cells.
Topics: Adenocarcinoma; Antibody Specificity; Colonic Neoplasms; Culture Techniques; Cytotoxicity Tests, Imm | 1975 |
About the influence of halogenated pyrimidines on the in vivo-oncogenesis.
Topics: Animals; Bromodeoxyuridine; Cricetinae; Female; Fibrosarcoma; Friend murine leukemia virus; Idoxurid | 1977 |
Recovery of three distinct biologically active type C viruses from cloned C57Bl/6 melanoma cells.
Topics: Animals; Cell Line; Clone Cells; Cycloheximide; Idoxuridine; Leukemia Virus, Murine; Melanins; Melan | 1979 |
Altered thymidylate kinase substrate specificity in mammalian cells selected for resistance to iododeoxyuridine.
Topics: Animals; Biological Transport; Cell Line; Cricetinae; Deoxyuracil Nucleotides; DNA; Drug Resistance; | 1979 |
An in vitro quantitative assay for tumor cell invasion.
Topics: Allantois; Animals; Cell Line; Chick Embryo; Chorion; Idoxuridine; Melanoma; Methods; Neoplasm Invas | 1978 |
Enhancement of incorporation of 131iododeoxyuridine into tumors after application of Clostridium oncolyticum s. butyricum (M 55). Animal experiments on positive scintigraphic localization of tumors.
Topics: Animals; Carcinoma; Clostridium; Cricetinae; Idoxuridine; Image Enhancement; Iodine Radioisotopes; M | 1977 |
Survey of human lymphoblastoid cell lines and primary cultures of normal and leukaemic leukocytes for oncornavirus production.
Topics: Burkitt Lymphoma; Cell Line; Culture Media; Humans; Idoxuridine; Leukemia; Leukocytes; Melanoma; Mit | 1976 |
Biological behavior of malignant melanoma cells correlated to their survival in vivo.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Survival; Idoxuridine; Iodine Radioisotopes; Lun | 1975 |
In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity.
Topics: Animals; Cell Count; Cells, Cultured; Culture Techniques; Cytotoxicity Tests, Immunologic; Embryo, M | 1975 |
Activation in vitro of mouse macrophages by syngeneic, allogeneic, or xenogeneic lymphocyte supernatants.
Topics: Animals; Cytotoxicity Tests, Immunologic; Idoxuridine; Lymphocytes; Macrophages; Melanoma; Mice; Mic | 1975 |
Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells.
Topics: Animals; Bromodeoxyuridine; Catechol Oxidase; Cell Line; Cell Transformation, Neoplastic; Floxuridin | 1990 |
Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice.
Topics: Animals; Cell Division; Cell Line; Humans; Idoxuridine; Interleukin-1; Interleukin-6; Iodine Radiois | 1990 |
Membrane-associated interleukin 1 alpha as a mediator of tumor cell killing by human blood monocytes fixed with paraformaldehyde.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cell Communication; Cell Line; Cell Membrane; Colonic Neoplasms; | 1989 |
Effects of tertiary amine local anesthetics on the blood-borne implantation and cell surface properties of metastatic mouse melanoma cells.
Topics: Anesthetics, Local; Animals; Calcium; Cell Adhesion; Cell Membrane; Cytoskeleton; Female; Glycoprote | 1986 |
Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Idoxuridine; Iodine Radioisotopes; Male; Melanom | 1986 |
[Effect of x-irradiation on the kinetics of 5-iodo-2'-deoxyuridine in a tumor].
Topics: Animals; Idoxuridine; Kinetics; Male; Melanoma; Mice; Mice, Inbred C57BL; Models, Biological; Neopla | 1986 |
[125I-iododeoxyuridine in the reaction of experimental tumors to irradiation].
Topics: Animals; Idoxuridine; Kinetics; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; P | 1986 |
Effectiveness of anticancer drugs determined in nude mice inoculated with [125I]5-iodo-2'-deoxyuridine-prelabeled human melanoma cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Cyclophosphamide; Diphtheria Toxin; Humans; Idoxuridine; | 1985 |
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neop | 1971 |
A lymphocytotoxicity assay not requiring the in vitro culture of target tumor cells.
Topics: Animals; Cells, Cultured; Cytotoxicity Tests, Immunologic; Idoxuridine; Immunization; Iodine Radiois | 1974 |
Enhancement of experimental metastasis by x-ray: a possible mechanism.
Topics: Animals; Cells, Cultured; Idoxuridine; Injections, Intravenous; Iodine Isotopes; Isotope Labeling; L | 1972 |
Use of an in vitro microcytotoxicity test to assess human tumor-specific cell-mediated immunity and its serum-mediated abrogation.
Topics: Antigens, Neoplasm; Brain Neoplasms; Cells, Cultured; Culture Media; Cytotoxicity Tests, Immunologic | 1973 |
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido | 1973 |
Ultrastructural effects of thymidine analogs in melanosomes and virus activation in cloned hamster melanoma cells in culture.
Topics: Animals; Bromodeoxyuridine; Clone Cells; Golgi Apparatus; Idoxuridine; Melanins; Melanocytes; Melano | 1973 |
A diffusion chamber method for the detection of lymphocyte-mediated cytotoxicity of 125 IUdR-labeled tumor cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cytotoxicity Tests, Immunologic; Diffusion; DNA; Idoxuridin | 1972 |
Metastasis: quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-iodo-2'-deoxyuridine.
Topics: Animals; Autoradiography; Clone Cells; Culture Techniques; Idoxuridine; Injections, Intravenous; Iod | 1970 |