idoxuridine has been researched along with Liver Neoplasms in 30 studies
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, the authors evaluate the biological effects of irradiation of hepatocellular carcinoma cells by internal exposure with (125)I-labeled 5-iodo-2'-deoxyuridine ((125)I-UdR)-chitosan drug loading nanoparticles ((125)I-UdR-CS-DLN)." | 7.80 | Biological effects of irradiating hepatocellular carcinoma cells by internal exposure with 125I-labeled 5-iodo-2'-deoxyuridine-chitosan drug loading nanoparticles. ( Jiang, B; Liu, F; Song, M; Wan, J; Yang, C; Zhou, D; Zhu, R, 2014) |
| "In this study, the authors evaluate the biological effects of irradiation of hepatocellular carcinoma cells by internal exposure with (125)I-labeled 5-iodo-2'-deoxyuridine ((125)I-UdR)-chitosan drug loading nanoparticles ((125)I-UdR-CS-DLN)." | 3.80 | Biological effects of irradiating hepatocellular carcinoma cells by internal exposure with 125I-labeled 5-iodo-2'-deoxyuridine-chitosan drug loading nanoparticles. ( Jiang, B; Liu, F; Song, M; Wan, J; Yang, C; Zhou, D; Zhu, R, 2014) |
| "To investigate hypoxia measured by pimonidazole binding, glucose transporter 1 (GLUT1) and carbonic anhydrase IX (CA-IX) expression, proliferation, and vascularity in liver metastases of colorectal cancer and to compare GLUT1 and CA-IX expression in corresponding primary tumors." | 3.73 | Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer. ( Heerschap, A; Kaanders, JH; Lok, J; Peeters, WJ; Punt, CJ; Rijken, PF; Ruers, TJ; van der Kogel, AJ; van Laarhoven, HW; Wiering, B, 2006) |
| "While most hepatocellular carcinomas (HCCs) in a relatively early stage contain only a small amount of necrosis, the growth rate supposedly depends mainly on growth fraction, cell-cycle time, and apoptosis." | 1.30 | Novel formula for cell kinetics in xenograft model of hepatocellular carcinoma using histologically calculable parameters. ( Ashihara, T; Deguchi, T; Kagawa, K; Kakusui, M; Kashima, K; Katagishi, T; Kimura, H; Mitsumoto, Y; Nakajima, T; Okanoue, T, 1999) |
| " Pharmacokinetic analysis of p." | 1.29 | An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116. ( Cheng, YC; Kinsella, TJ; Kunugi, KA; Liu, SH; McCulloch, W; Vielhuber, KA, 1994) |
| " Toward this goal, we have performed preclinical and clinical studies, using various routes of administration, to detect adverse changes in normal tissues in both humans and animals." | 1.29 | Radiolabeled iododeoxyuridine: safety evaluation. ( Augustine, SC; Baranowska-Kortylewicz, J; Chiou, RK; Cohen, SM; Dalrymple, GV; Harrison, KA; Holdeman, KP; Leichner, PK; Lieberman, RP; Schneiderman, MH; Sharp, JG; Taylor, RJ; Tempero, MA, 1996) |
| " This paper describes a new approach, based upon pharmacokinetic clearance of radioactivity from the tumor, with which to quantify the fraction of [125I]IUdR incorporated within the DNA of tumor cells." | 1.29 | Pharmacokinetics and dosimetry of iodine-125-IUdR in the treatment of colorectal cancer metastatic to liver. ( Daghighian, F; Finn, R; Humm, JL; Izzo, J; Kemeny, N; Larson, SM; Macapinlac, HA; Zhang, J, 1996) |
| "Potential doubling times for the tumors were estimated to be 10 days." | 1.28 | Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies. ( Belanger, K; Chang, AE; Collins, JM; Cupp, JE; Kinsella, TJ; Klecker, RW; Rowland, J; Smith, R; Speth, PA, 1989) |
| "Cultures of two human hepatoma cell lines were examined for expression of hepatitis B virus surface antigen (HBsAg)." | 1.26 | Induction of hepatitis B surface antigen in human hepatoma-derived cell lines. ( Bronson, DL; Dreesman, GR; Oefinger, PE, 1981) |
| "A rat tropic rat hepatoma virus pseudotype Kirsten sarcoma virus has been rescued from a co-culture of rat hepatoma tissue culture cells, HTC-HI, with Kirsten murine sarcoma transformed non-producer rat kidney cells (K-NRK)." | 1.26 | Rescue of a rat tropic rat hepatoma virus pseudotype Kirsten sarcoma virus by co-cultivation of hepatoma tissue culture cells with K-NRK cells. ( Chan, C; Thompson, EB; Yang, SS, 1976) |
| "As a model of blood-borne metastasis, the ascitic form of hepatoma AH-109A tumor was injected intravenously into Donryu strain rats." | 1.26 | Effect of sulfated polysaccharides on blood-borne pulmonary metastasis in rats. ( Higuchi, Y; Kobayashi, M; Tsubura, E; Yamashita, T, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (53.33) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, C | 1 |
| Zhu, R | 1 |
| Wan, J | 1 |
| Jiang, B | 1 |
| Zhou, D | 1 |
| Song, M | 1 |
| Liu, F | 1 |
| Ou, XH | 1 |
| Kuang, AR | 1 |
| Peng, X | 1 |
| Zhong, YG | 1 |
| BOOTH, BA | 1 |
| SARTORELLI, AC | 1 |
| OEHLERT, W | 1 |
| MAGNUSSON, B | 1 |
| FOX, BW | 1 |
| PRUSOFF, WH | 1 |
| Wang, HE | 1 |
| Wu, HC | 1 |
| Kao, SJ | 1 |
| Tseng, FW | 1 |
| Wang, YS | 1 |
| Yu, HM | 1 |
| Chou, SL | 1 |
| Yen, SH | 1 |
| Chi, KH | 1 |
| van Laarhoven, HW | 1 |
| Kaanders, JH | 1 |
| Lok, J | 1 |
| Peeters, WJ | 1 |
| Rijken, PF | 1 |
| Wiering, B | 1 |
| Ruers, TJ | 1 |
| Punt, CJ | 1 |
| Heerschap, A | 1 |
| van der Kogel, AJ | 1 |
| Oefinger, PE | 1 |
| Bronson, DL | 1 |
| Dreesman, GR | 1 |
| Xu, ZL | 1 |
| Rieber, M | 1 |
| Meza, AT | 1 |
| Kinsella, TJ | 6 |
| Kunugi, KA | 1 |
| Vielhuber, KA | 1 |
| McCulloch, W | 1 |
| Liu, SH | 1 |
| Cheng, YC | 1 |
| Harrison, KA | 1 |
| Dalrymple, GV | 1 |
| Baranowska-Kortylewicz, J | 3 |
| Holdeman, KP | 1 |
| Schneiderman, MH | 1 |
| Lieberman, RP | 1 |
| Sharp, JG | 1 |
| Cohen, SM | 1 |
| Leichner, PK | 1 |
| Augustine, SC | 1 |
| Tempero, MA | 1 |
| Taylor, RJ | 1 |
| Chiou, RK | 1 |
| Mariani, G | 2 |
| Di Sacco, S | 2 |
| Volterrani, D | 1 |
| Di Luca, L | 2 |
| Buralli, S | 2 |
| Di Stefano, R | 1 |
| Bonora, D | 2 |
| Matteucci, F | 1 |
| Ricci, S | 2 |
| Bellina, CR | 1 |
| Falcone, A | 2 |
| Salvadori, PA | 1 |
| Mosca, F | 1 |
| Adelstein, SJ | 2 |
| Kassis, AI | 2 |
| Daghighian, F | 2 |
| Humm, JL | 1 |
| Macapinlac, HA | 2 |
| Zhang, J | 2 |
| Izzo, J | 1 |
| Finn, R | 2 |
| Kemeny, N | 3 |
| Larson, SM | 3 |
| Humm, J | 1 |
| Squire, O | 1 |
| Bonini, R | 1 |
| Sgouros, G | 1 |
| O'Donoghue, JA | 1 |
| Macapinlac, H | 1 |
| Larson, JJ | 1 |
| Nakajima, T | 1 |
| Kagawa, K | 1 |
| Deguchi, T | 1 |
| Kimura, H | 1 |
| Kakusui, M | 1 |
| Katagishi, T | 1 |
| Mitsumoto, Y | 1 |
| Okanoue, T | 1 |
| Kashima, K | 1 |
| Ashihara, T | 1 |
| Yang, SS | 1 |
| Chan, C | 1 |
| Thompson, EB | 1 |
| Tsubura, E | 1 |
| Yamashita, T | 1 |
| Kobayashi, M | 1 |
| Higuchi, Y | 1 |
| Calabresi, P | 1 |
| Curt, G | 1 |
| Ensminger, W | 1 |
| Chang, AE | 3 |
| Collins, JM | 4 |
| Speth, PA | 3 |
| Smith, R | 2 |
| Rowland, JB | 1 |
| Walton, L | 1 |
| Begley, MG | 1 |
| Glatstein, E | 2 |
| Klecker, RW | 2 |
| Belanger, K | 2 |
| Rowland, J | 2 |
| Cupp, JE | 1 |
| Remick, SC | 1 |
| Benson, AB | 1 |
| Weese, JL | 1 |
| Willson, JK | 1 |
| Ramirez, G | 1 |
| Wirtanen, GW | 1 |
| Alberti, DB | 1 |
| Nieting, LM | 1 |
| Tutsch, KD | 1 |
| Fischer, PH | 1 |
| Russo, A | 1 |
| Mitchell, JB | 1 |
| Wright, D | 1 |
| Dunkel, VC | 1 |
| Bast, RC | 1 |
| Gerwin, BI | 1 |
| Heine, U | 1 |
| Cottler-Fox, M | 1 |
| Borsos, T | 1 |
| Georgatsos, JG | 1 |
| Antonoglou, O | 1 |
| Gabrielides, C | 1 |
1 review available for idoxuridine and Liver Neoplasms
| Article | Year |
|---|---|
Hepatic arterial chemotherapy for primary and metastatic liver cancers.
Topics: Bromodeoxyuridine; Combined Modality Therapy; Hepatic Artery; Humans; Idoxuridine; Infusions, Intra- | 1989 |
1 trial available for idoxuridine and Liver Neoplasms
| Article | Year |
|---|---|
Pilot clinical trial of 5-[125I]iodo-2'-deoxyuridine in the treatment of colorectal cancer metastatic to the liver.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Hepatic Artery; Humans; Ido | 1996 |
28 other studies available for idoxuridine and Liver Neoplasms
| Article | Year |
|---|---|
Biological effects of irradiating hepatocellular carcinoma cells by internal exposure with 125I-labeled 5-iodo-2'-deoxyuridine-chitosan drug loading nanoparticles.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Chitosan; DNA Damage; DNA Repair; Hep G2 Cells; Human | 2014 |
Study on the possibility of insulin as a carrier of IUdR for hepatocellular carcinoma-targeted therapy.
Topics: Binding Sites; Binding, Competitive; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid | 2003 |
GROWTH INHIBITION OF A SPECTRUM OF TRANSPLANTED MOUSE TUMORS BY COMBINATIONS OF INHIBITORS OF NUCLEIC ACID BIOSYNTHESIS AND ALKYLATING AGENTS.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; | 1963 |
[AUTORADIOGRAPHIC STUDIES ON THE INCORPORATION OF 5-IODO-2-DESOXYURIDINE (IUDR) INTO THE DNA OF CELLS OF YOSHIDA HEPATOMA AH 130].
Topics: Autoradiography; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Idoxuridine; Liver Neoplasms; Neopla | 1965 |
THE COMPARATIVE UPTAKE OF I-125-LABELED 5-IODO-2'-DEOXYURIDINE AND THYMIDINE-H3 INTO TISSUES OF MICE BEARING HEPATOMA-129.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Histocytochemistry; Idoxuridine; Inte | 1965 |
Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-kappaB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on human hepatoma cell.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Down-Regulation; Fluorouracil; Humans; Idoxuridine; Iod | 2005 |
Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Carbonic Anhydrases; Cell Hypoxia; Cell Proliferation; Colorectal Ne | 2006 |
Induction of hepatitis B surface antigen in human hepatoma-derived cell lines.
Topics: Carcinoma, Hepatocellular; Cell Line; Culture Media; Dexamethasone; Hepatitis B Core Antigens; Hepat | 1981 |
[The role of macrophage against cancer growth. I. Cytostatic effect of human macrophage on hepatoma cell].
Topics: Carcinoma, Hepatocellular; Cell Line; Cytotoxicity, Immunologic; Humans; Idoxuridine; Liver Neoplasm | 1983 |
Anodic migration of actin and increased levels of a cathodic fibronectin among the cytoskeletal changes that correlate with increased cell adherence in liver epitheloid tumor cells.
Topics: Actins; Animals; Carcinoma; Cell Adhesion; Electrophysiology; Fibronectins; Idoxuridine; Liver Neopl | 1981 |
An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116.
Topics: Administration, Oral; Animals; Colonic Neoplasms; DNA; Female; Humans; Idoxuridine; Liver; Liver Neo | 1994 |
Correspondence re: J.A. Knol et al., Incorporation of 5-bromo-2-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion. Cancer Res., 55: 3687-3691, 1995.
Topics: Bromodeoxyuridine; Colorectal Neoplasms; DNA, Neoplasm; Humans; Idoxuridine; Liver; Liver Neoplasms; | 1996 |
Radiolabeled iododeoxyuridine: safety evaluation.
Topics: Administration, Intravesical; Animals; Female; Humans; Idoxuridine; Injections, Intra-Arterial; Iodi | 1996 |
Tumor targeting by intra-arterial infusion of 5-[123I]iodo-2'-deoxyuridine in patients with liver metastases from colorectal cancer.
Topics: Aged; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Female; Hepatic Artery; Humans; Id | 1996 |
Pharmacokinetics and dosimetry of iodine-125-IUdR in the treatment of colorectal cancer metastatic to liver.
Topics: Bone Marrow; Colorectal Neoplasms; Hepatic Artery; Humans; Idoxuridine; Injections, Intra-Arterial; | 1996 |
Biochemical modulation by 5-fluorouracil and 1-folinic acid of tumor uptake of intra-arterial 5-[123I]iodo-2'deoxyuridine in patients with liver metastases from colorectal cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Colorectal Neoplasms; Feasibility Studies; Fluorouracil; Huma | 1996 |
Mathematical model of 5-[125I]iodo-2'-deoxyuridine treatment: continuous infusion regimens for hepatic metastases.
Topics: Antimetabolites, Antineoplastic; Cell Count; Feasibility Studies; Humans; Idoxuridine; Infusions, In | 1998 |
Novel formula for cell kinetics in xenograft model of hepatocellular carcinoma using histologically calculable parameters.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Humans; Idoxuridine; Kinetics; Liver Neoplasm | 1999 |
Rescue of a rat tropic rat hepatoma virus pseudotype Kirsten sarcoma virus by co-cultivation of hepatoma tissue culture cells with K-NRK cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Line; Cell Transformation, Neoplastic; G | 1976 |
Effect of sulfated polysaccharides on blood-borne pulmonary metastasis in rats.
Topics: Animals; Blood Coagulation; Carcinoma, Hepatocellular; Chondroitin Sulfates; Female; Fibrinolysis; I | 1976 |
Incorporation of iododeoxyuridine into neoplastic DNA: a fraudulent magic bullet?
Topics: Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Humans; Idoxuridine; Liver; Liver Neoplasms; Thymid | 1990 |
A phase I study of intraarterial iododeoxyuridine in patients with colorectal liver metastases.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Combined Modality Therapy; DNA, Neoplasm; Drug Evaluati | 1989 |
Iododeoxyuridine (IdUrd) incorporation into DNA of human hematopoietic cells, normal liver and hepatic metastases in man: as a radiosensitizer and as a marker for cell kinetic studies.
Topics: Cell Cycle; Combined Modality Therapy; DNA; DNA, Neoplasm; Granulocytes; Humans; Idoxuridine; Infusi | 1989 |
Phase I trial of hepatic artery infusion of 5-iodo-2'-deoxyuridine and 5-fluorouracil in patients with advanced hepatic malignancy: biochemically based combination chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dogs; Drug Evaluation; Female; Fluorouracil | 1989 |
A phase I study of intravenous iododeoxyuridine as a clinical radiosensitizer.
Topics: Biopsy; Drug Evaluation; Duodenal Neoplasms; Glioblastoma; Humans; Idoxuridine; Liver Neoplasms; Rad | 1985 |
Selective incorporation of iododeoxyuridine into DNA of hepatic metastases versus normal human liver.
Topics: Adult; Aged; DNA; DNA, Neoplasm; Female; Flow Cytometry; Humans; Idoxuridine; Liver; Liver Neoplasms | 1988 |
Presence of A-type and absence of C-type virus particles in a chemically induced guinea pig hepatoma.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Hepatocellular; Cells, Cultured; Guinea Pigs; Id | 1974 |
Incorporation of 5-iodo-2'-deoxyuridine-131-I into nuclear and mitochondrial DNA of normal and malignant mouse tissues.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Chromatography, Gel; DNA; DNA, Neoplasm; Female; I | 1970 |