Page last updated: 2024-11-07

idoxuridine and Leukemia

idoxuridine has been researched along with Leukemia in 21 studies

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
" The killing of cells and apparent beneficial effect of tritiated thymidine in human leukemia are described."4.76Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia? ( Cronkite, EP; Fairchild, RG; Miller, ME, 1983)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199018 (85.71)18.7374
1990's3 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
EIDINOFF, ML1
CHEONG, L1
GURPIDE, EG1
BENUA, RS1
ELLISON, RR1
CALABRESI, P1
CREASEY, WA1
PRUSOFF, H1
WELCH, AD1
DELAMORE, IW1
PRUSOFF, WH2
FISCHER, GA2
VONESSEN, CF1
MATHIAS, AP1
McCubrey, J1
Risser, R1
Cronkite, EP1
Fairchild, RG1
Miller, ME1
Salahuddin, SZ1
Markham, PD1
Wong-Staal, F1
Franchini, G1
Kalyanaraman, VS1
Gallo, RC1
Herberman, RB1
Longenecker, BM1
Menezes, J1
Sanders, EJ1
Pazderka, F1
Ruth, RF1
Klucis, E1
Jackson, L1
Parsons, PG1
Sadler, TE1
Alexander, P1
Myers, DK1
Minderman, H1
Brons, PP1
Linssen, PC1
Pennings, AH1
Wessels, JM1
Boezeman, JB1
Haanen, C1
Miller, MA2
Mazewski, CM1
Yousuf, N1
Sheikh, Y2
White, LM1
Yanik, GA1
Hyams, DM1
Lampkin, BC1
Raza, A2
Mazewski, C1
Lampkin, B1
Sawaya, R1
Crone, K1
Berger, T1
Reising, J1
Gray, J1
Naito, K1
Yamada, K1
Lee, SY1
Muller, SA1
Herrmann, EC1
Winkelmann, RK1
Brunell, PA1
Gershon, AA1
Forman, J1
Ketchel, MM1
Hofer, KG1

Reviews

3 reviews available for idoxuridine and Leukemia

ArticleYear
Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia?
    Blood cells, 1983, Volume: 9, Issue:1

    Topics: Acute Disease; Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemical Fractionation; DN

1983
Herpes simplex infections in hematologic malignancies.
    The American journal of medicine, 1972, Volume: 52, Issue:1

    Topics: Adult; Aged; Female; Herpes Simplex; Hodgkin Disease; Humans; Idoxuridine; Leukemia; Leukemia, Lymph

1972
Passive immunization against varicella-zoster infections and other modes of therapy.
    The Journal of infectious diseases, 1973, Volume: 127, Issue:4

    Topics: Adult; Blood Transfusion; Chickenpox; Child; Cross Infection; Cytarabine; Female; Herpes Zoster; Hum

1973

Other Studies

18 other studies available for idoxuridine and Leukemia

ArticleYear
Incorporation of 5-iodouracil labelled with iodine-131 into the deoxyribonucleic acid of human leukaemic leucocytes following in vivo administration of 5-iododeoxyuridine labelled with iodine-131.
    Nature, 1959, Jun-13, Volume: 183, Issue:4676

    Topics: DNA; Idoxuridine; Iodine; Leukemia; Leukocytes; Nucleosides; Nucleotides; Uracil

1959
Clinical and pharmacological studies with 5-iodo-2'-deoxycytidine.
    Cancer research, 1963, Volume: 23

    Topics: Adenocarcinoma; Bromodeoxycytidine; Carcinoma; Carcinoma, Squamous Cell; Deoxycytidine; Hodgkin Dise

1963
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE.
    Biochimica et biophysica acta, 1964, Feb-17, Volume: 80

    Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimen

1964
THE COMPARISON OF RADIATION AND ANTIMETABOLITE RESPONSES OF GENETICALLY ALTERED MURINE LEUKEMIC CELLS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Animals; Antimetabolites; Chromosomes; Floxuridine; Genetics; Idoxuridine; Leukemia; Leukemia, Exper

1965
Inhibition of the growth of mouse leukemia cells in culture by 5-iododeoxyuridine.
    Biochimica et biophysica acta, 1959, Volume: 36

    Topics: Diploidy; Idoxuridine; Leukemia; Leukemia, Experimental; Nucleosides; Nucleotides; Physiological Phe

1959
Genetic interactions in induction of endogenous murine leukemia virus from low leukemic mice.
    Cell, 1982, Volume: 28, Issue:4

    Topics: Animals; Cells, Cultured; Crosses, Genetic; Embryo, Mammalian; Idoxuridine; Leukemia; Leukemia Virus

1982
Restricted expression of human T-cell leukemia--lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes.
    Virology, 1983, Volume: 129, Issue:1

    Topics: Cell Fusion; Cell Transformation, Viral; Cells, Cultured; Fetal Blood; Genes, Viral; Humans; Idoxuri

1983
Cell-mediated cytotoxic reactions to tumor associated antigens.
    Journal of the Reticuloendothelial Society, 1975, Volume: 17, Issue:4

    Topics: Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; B-Lymphocytes; Chromium Radioisotopes; Cyto

1975
A new class of infectious agents detectable by the production of chorioallantoic membrane lesions by human lymphoblastoid cell lines and their culture supernatants.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4

    Topics: Allantois; Animals; Antibodies, Viral; Bromodeoxyuridine; Burkitt Lymphoma; Cell Line; Cell Transfor

1977
Survey of human lymphoblastoid cell lines and primary cultures of normal and leukaemic leukocytes for oncornavirus production.
    International journal of cancer, 1976, Oct-15, Volume: 18, Issue:4

    Topics: Burkitt Lymphoma; Cell Line; Culture Media; Humans; Idoxuridine; Leukemia; Leukocytes; Melanoma; Mit

1976
Trapping and destruction of blood-borne syngeneic leukaemia cells in lung, liver and spleen of normal and leukaemic rats.
    British journal of cancer, 1976, Volume: 33, Issue:5

    Topics: Animals; Bone Marrow; Cell Survival; Female; Idoxuridine; Leukemia; Leukemia, Experimental; Leukemia

1976
Effect of iododeoxyuridine on tumor induction in X-irradiated rats.
    Experientia, 1975, Jun-15, Volume: 31, Issue:6

    Topics: Animals; Body Weight; Female; Idoxuridine; Leukemia; Lymphoma; Male; Mammary Glands, Animal; Neoplas

1975
Effect of doxorubicin exposure on cell-cycle kinetics of human leukemia cells studied by bivariate flow cytometric measurement of 5-iodo-2-deoxyuridine incorporation and DNA content.
    Experimental hematology, 1991, Volume: 19, Issue:10

    Topics: Cell Cycle; Cell Survival; DNA; Doxorubicin; Flow Cytometry; Humans; Idoxuridine; Kinetics; Leukemia

1991
Simultaneous immunohistochemical detection of IUdR and BrdU infused intravenously to cancer patients.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1991, Volume: 39, Issue:4

    Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Humans; I

1991
Observations regarding DNA replication sites in human cells in vivo following infusions of iododeoxyuridine and bromodeoxyuridine.
    Cell proliferation, 1991, Volume: 24, Issue:2

    Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Nucleus; DNA Replication; Gastroint

1991
[Serum deoxythymidine kinase in hematological malignancy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:12

    Topics: Acute Disease; Adult; Chronic Disease; Humans; Idoxuridine; Leukemia; Myelodysplastic Syndromes; Thy

1988
Current status of the host-mediated L5178Y system for detecting chemical mutagens.
    Environmental health perspectives, 1973, Volume: 6

    Topics: Alkylating Agents; Animals; Bromodeoxyuridine; Cell Line; Cells, Cultured; Cyclophosphamide; Ethylen

1973
Tumor immunity in vivo: use of the 125 IUdR prelabeling technique to monitor cell death in immune animals.
    Transplantation, 1972, Volume: 14, Issue:2

    Topics: Animals; Antigens; Antigens, Neoplasm; Cell Movement; Cell Survival; Cytotoxicity Tests, Immunologic

1972