idoxuridine has been researched along with Leukemia L 1210 in 30 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Among these compounds, 3'-amino-2',3'-dideoxy-5-fluorouridine (3), 3'-amino-2',3'-dideoxycytidine (7a), and 3'-amino-2',3'-dideoxy-5-fluorocytidine (7c) were found to be the most active against murine L1210 and sarcoma 180 neoplastic cells in vitro, with an ED50 of 15 and 1 microM, 0." | 3.66 | Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides. ( Gao, YS; Lin, TS; Mancini, WR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (96.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Béres, J | 1 |
| Sági, G | 1 |
| Bentrude, WG | 1 |
| Balzarini, J | 4 |
| De Clercq, E | 4 |
| Otvös, L | 1 |
| Al-Razzak, LA | 1 |
| Schwepler, D | 1 |
| Decedue, CJ | 1 |
| Mertes, MP | 1 |
| Robins, MJ | 2 |
| Hatfield, PW | 1 |
| Shiau, GT | 1 |
| Schinazi, RF | 1 |
| Chen, MS | 1 |
| Prusoff, WH | 2 |
| Descamps, J | 1 |
| Giziewicz, J | 1 |
| Barr, PJ | 1 |
| Lin, TS | 2 |
| Gao, YS | 1 |
| Mancini, WR | 1 |
| Gibbs, DD | 1 |
| Theti, DS | 1 |
| Wood, N | 1 |
| Green, M | 1 |
| Raynaud, F | 1 |
| Valenti, M | 1 |
| Forster, MD | 1 |
| Mitchell, F | 1 |
| Bavetsias, V | 1 |
| Henderson, E | 1 |
| Jackman, AL | 1 |
| Kan-Mitchell, J | 1 |
| Mitchell, MS | 1 |
| Graczyk, J | 1 |
| Kowalczyk, K | 1 |
| Pakulska, W | 1 |
| Szadowska, A | 1 |
| Wheelock, EF | 1 |
| Weinhold, KJ | 1 |
| Ingenito, GG | 1 |
| Goldstein, LT | 1 |
| Carlson, GA | 2 |
| Wegmann, TG | 1 |
| Hofer, KG | 8 |
| Choppin, DA | 1 |
| Hofer, MG | 1 |
| Terres, G | 1 |
| Lee, DJ | 1 |
| Prensky, W | 3 |
| Krause, G | 1 |
| Hughes, WL | 5 |
| Fioretti, MC | 2 |
| Libarati, M | 1 |
| Bonmassar, E | 2 |
| Cudkowicz, G | 1 |
| Chou, TC | 1 |
| Hutchinson, DJ | 1 |
| Schmid, FA | 1 |
| Philips, FS | 1 |
| Bruckner, HW | 1 |
| Schreiber, C | 1 |
| Waxman, S | 1 |
| Houchens, DP | 1 |
| Goldin, A | 1 |
| Carchman, RA | 1 |
| Harris, LS | 1 |
| Munson, AE | 1 |
| Belanger, K | 1 |
| Collins, JM | 1 |
| Klecker, RW | 1 |
| Andrysek, O | 1 |
| Bláhová, E | 1 |
| Gregora, V | 1 |
| Rezný, Z | 1 |
| Warters, RL | 1 |
| Rolfes, TH | 1 |
| Hofer, M | 2 |
| Swartzendruber, DC | 1 |
| Loewenstein, D | 1 |
| Ketchel, MM | 1 |
| Reif, AE | 1 |
| Kim, CA | 1 |
| Rosenoff, S | 1 |
| Fox, JJ | 1 |
| Miller, N | 1 |
| Wempen, I | 1 |
1 review available for idoxuridine and Leukemia L 1210
| Article | Year |
|---|---|
Paternal-strain antigen excess in semiallogeneic pregnancy.
Topics: Absorption; Animals; Female; Histocompatibility Antigens; Idoxuridine; Leukemia L1210; Male; Mice; M | 1978 |
29 other studies available for idoxuridine and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Deoxyuracil Nucleotides; Drug Evaluatio | 1986 |
5-Quinone derivatives of 2'-deoxyuridine 5'-phosphate: inhibition and inactivation of thymidylate synthase, antitumor cell, and antiviral studies.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Division; Cell Line; Cell Survival; Deoxyurac | 1987 |
Nucleic acid related compounds. 47. Synthesis and biological activities of pyrimidine and purine "acyclic" nucleoside analogues.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Kidney; Leukemia L1210; Mice; | 1984 |
Synthesis and biological activities of 5-(hydroxymethyl, azidomethyl, or aminomethyl)-2'-deoxyuridine and related 5'-substituted analogues.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Deoxyribonucleosides; Female; Kin | 1980 |
Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides.
Topics: Alkynes; Animals; Cell Survival; Idoxuridine; Leukemia L1210; Mice; Rabbits; Simplexvirus; Substrate | 1983 |
Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides.
Topics: Animals; Antineoplastic Agents; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; Leukemia L1210; M | 1983 |
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
Topics: Animals; Apoptosis; Biological Transport; Carrier Proteins; Cell Proliferation; Choriocarcinoma; Enz | 2005 |
Comparative analysis of the immunosuppressive properties of two antiviral, iodinated thymidine analogs, 5-iodo-2'-deoxyuridine and 5-iodo-5'-amino-2',5'-dideoxyuridine.
Topics: Animals; Cytotoxicity, Immunologic; Female; Hemagglutinins; Idoxuridine; Immunity, Cellular; Immunos | 1980 |
[Effect of selected piperazine derivatives on the metabolic clearance rate of idoxuridine-I-125 in mice with transplanted leukemia L1210].
Topics: Animals; Antineoplastic Agents; Female; Idoxuridine; Iodine Radioisotopes; Leukemia L1210; Metabolic | 1981 |
In vivo lysis of L5178Y cells in the establishment of the tumor-dormant state in DBA/2 mice.
Topics: Animals; Cell Transformation, Neoplastic; Chromium Radioisotopes; Cytotoxicity, Immunologic; Diffusi | 1980 |
Effect of hyperthermia on the radiosensitivity of normal and malignant cells in mice.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Dose-Response Relationship, Radiation; Female; Hyp | 1976 |
Antibody-induced killing in vivo of L1210/MTX-R cells quantitated in passively immunized mice with 131I-iododeoxyuridine-labeled cells and whole-body measurement of retained radioactivity.
Topics: Animals; Antibodies, Neoplasm; Cell Survival; Complement System Proteins; Cytotoxicity Tests, Immuno | 1976 |
Blood thymidine level and iododeoxyuridine incorporation and reutilization in DNA in mice given long-acting thymidine pellets.
Topics: Animals; Binding, Competitive; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Drug Implants; Fema | 1976 |
Immune inhibition of allogeneic lymphoma cells in the peritoneal cavity of mice.
Topics: Animals; Antibody Specificity; Ascitic Fluid; DNA, Neoplasm; Female; Histocompatibility Antigens; Id | 1975 |
Metabolism and selective effects of 1-beta-D-arabinofuranosylcytosine in L1210 and Host tissues in vivo.
Topics: Animals; Ascitic Fluid; Cytarabine; DNA, Neoplasm; Idoxuridine; Intestine, Small; Leukemia L1210; Li | 1975 |
Interaction of chemotherapeutic agents with methotrexate and 5-fluorouracil and its effect on de novo DNA synthesis.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cephalosporins; Dexamethasone; DNA; DNA, Neoplasm; Fluorour | 1975 |
Uptake of 5-iododeoxyuridine as a measure of tumor growth and tumor inhibition.
Topics: Animals; Carmustine; Cell Transformation, Neoplastic; Cyclophosphamide; DNA, Neoplasm; Female; Idoxu | 1975 |
The inhibition of DNA synthesis by cannabinoids.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cannabidiol; Cannabis; Cyclophosphamide; Cytarabine; DNA; D | 1976 |
Technique for detection of DNA nucleobases by reversed-phase high-performance liquid chromatography optimized for quantitative determination of thymidine substitution by iododeoxyuridine.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; DNA; DNA, Neoplasm; Humans; Hydrolysis; Id | 1987 |
An experimental model for predicting the synergism of hyperthermia with cytostatics.
Topics: Animals; Antineoplastic Agents; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Hyperthermia, I | 1985 |
Viability of tumor cells in mechanically and enzymatically prepared tissue suspensions.
Topics: Animals; Cell Biology; Cell Survival; Coloring Agents; DNA; Evaluation Studies as Topic; Histologica | 1974 |
Ga-citrate and I-iododeoxyuridine as markers for in vivo evaluation of tumor cell metastasis and death.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Evaluation Studies as Topic; Female; Gallium; Idox | 1973 |
Impenetrability of the mouse placenta to maternal leukemia cells.
Topics: Animals; Female; Hyaluronoglucosaminidase; Idoxuridine; Iodine Isotopes; Leukemia L1210; Maternal-Fe | 1971 |
Leukemia L1210 therapy trials with antileukemia serum and Bacillus Calmette-Guérin.
Topics: Animals; Hemagglutination Tests; Idoxuridine; Immunity, Cellular; Immunization, Passive; Immunoglobu | 1971 |
Death and metastatic distribution of tumor cells in mice monitored with 125I-iododeoxy-uridine.
Topics: Animals; Carcinoma, Ehrlich Tumor; Idoxuridine; Iodine Isotopes; Leukemia L1210; Mice; Neoplasm Meta | 1969 |
Kinetics of proliferation, migration, and death of L1210 ascites cells.
Topics: Animals; Ascitic Fluid; Autoradiography; Cell Count; Cell Division; Cell Movement; Cell Survival; DN | 1971 |
Radiotoxicity of intranuclear tritium, 125 iodine and 131 iodine.
Topics: Animals; Cell Count; Cell Nucleus; Cell Survival; DNA, Neoplasm; Female; Half-Life; Idoxuridine; Iod | 1971 |
Spontaneous and amethopterin-induced death of L1210 leukaemia cells in vivo.
Topics: Animals; DNA, Neoplasm; Idoxuridine; Injections, Intramuscular; Injections, Intraperitoneal; Iodine | 1969 |
Nucleosides. XXIX. 1-beta-D-arabinofuranosyl-5-fluorocytosine and related arabino nucleosides.
Topics: Animals; Arabinose; Chemistry, Organic; Cytosine; Fluorouracil; Furans; Idoxuridine; Keratitis, Dend | 1966 |