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idoxuridine and Leukemia, Myeloid, Acute

idoxuridine has been researched along with Leukemia, Myeloid, Acute in 6 studies

Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.

Research Excerpts

ExcerptRelevanceReference
"Examination of the proliferative characteristics of myeloblasts was undertaken in situ in bone marrow (BM) biopsies of patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) following sequential infusions of iodo- (IUdR) and bromodeoxyuridine (BrdU)."3.68In situ cell cycle kinetics in bone marrow biopsies following sequential infusions of IUdR/BrdU in patients with hematopoietic malignancies. ( Akhtar, S; Bohkari, SA; Chughtai, S; Masterson, M; Mehdi, SA; Miller, MA; Raza, A; Sheikh, Y; Umerani, A; Yousuf, N, 1992)
"Also in acute myeloid leukemia (AML), the proliferation rate (percentage S/G(2)+M and Iododeoxyuridine labelings index) was significantly less in the RhoD blasts (P 1.30Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance. ( de Witte, T; Pennings, AH; Raymakers, RA; Smeets, ME; Vierwinden, G; Wessels, H, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keoffler, HP1
Yen, J1
Carlson, J1
Smeets, ME1
Raymakers, RA1
Vierwinden, G1
Pennings, AH1
Wessels, H1
de Witte, T1
Falcão, RP1
Sonis, S1
MacLennan, IC1
Chassoux, D1
Davies, AJ1
Munro, TR1
Sadler, TE1
Alexander, P1
Raza, A1
Yousuf, N1
Bohkari, SA1
Sheikh, Y1
Akhtar, S1
Chughtai, S1
Umerani, A1
Mehdi, SA1
Miller, MA1
Masterson, M1
Lepri, E1
Liberati, M1
Portuese, MG1
Menconi, E1
Santucci, A1
Barzi, A1

Other Studies

6 other studies available for idoxuridine and Leukemia, Myeloid, Acute

ArticleYear
The study of human myeloid differentiation using bromodeoxyuridine (BrdU).
    Journal of cellular physiology, 1983, Volume: 116, Issue:1

    Topics: Bromodeoxyuridine; Cell Differentiation; Cell Line; Deoxycytidine; DNA; Granulocytes; Humans; Idoxur

1983
Triggering noncycling hematopoietic progenitors and leukemic blasts to proliferate increases anthracycline retention and toxicity by downregulating multidrug resistance.
    Blood, 1999, Oct-01, Volume: 94, Issue:7

    Topics: Antibiotics, Antineoplastic; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1

1999
Assessment of drug sensitivity of human leukaemic myeloblasts. I. Labelling human myeloblasts with 125IUdR for survival studies in mice.
    British journal of cancer, 1977, Volume: 36, Issue:3

    Topics: Animals; Blood Cells; Bone Marrow Cells; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinica

1977
Trapping and destruction of blood-borne syngeneic leukaemia cells in lung, liver and spleen of normal and leukaemic rats.
    British journal of cancer, 1976, Volume: 33, Issue:5

    Topics: Animals; Bone Marrow; Cell Survival; Female; Idoxuridine; Leukemia; Leukemia, Experimental; Leukemia

1976
In situ cell cycle kinetics in bone marrow biopsies following sequential infusions of IUdR/BrdU in patients with hematopoietic malignancies.
    Leukemia research, 1992, Volume: 16, Issue:3

    Topics: Biopsy; Biopsy, Needle; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Humans; Idoxuridine; Leukemia, M

1992
In vitro chemosensitivity of newly diagnosed and relapsing acute non-lymphoid leukemia patients.
    Tumori, 1991, Feb-28, Volume: 77, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Daunorubicin

1991