idoxuridine has been researched along with Glioma in 26 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two complimentary SSR approaches have been successfully developed in the past 5 years in our team, and may be promising in high-grade glioma management: iodine-enhanced SSR, with an iodinated contrast agent; and Pt-enhanced SSR; a concomitant radio-chemotherapy treatment with locoregional injection of platinated chemotherapy drugs." | 3.74 | Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment. ( Adam, JF; Balosso, J; Biston, MC; Boudou, C; Charvet, AM; Elleaume, H; Estève, F; Rousseau, J, 2008) |
| "Nineteen patients with human brain tumors (9 gliomas, 6 metastatic brain tumors, 3 meningiomas, 1 neurinoma) received intravenous infusions of iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) at different time sequences, to estimate the duration of S-phase (Ts) and the potential doubling time (Tp) of individual tumors." | 3.68 | [Proliferation kinetics of human brain tumors by in situ double labeling with bromodeoxyuridine and iododeoxyuridine]. ( Hoshino, T; Maeda, T, 1992) |
| "Fifty-seven patients with brain tumors (29 gliomas, 23 meningiomas, 5 miscellaneous) received infusions of intravenous iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) 1-5 hr apart shortly before tumor removal." | 3.68 | Cell kinetic analysis of human brain tumors by in situ double labelling with bromodeoxyuridine and iododeoxyuridine. ( Asai, A; Davis, RL; Dodson, BA; Hoshino, T; Ito, S; Prados, MD; Shibuya, M; Wilson, CB, 1992) |
| "Glioma is one of the most common malignant cancers of the central nervous system (CNS)." | 1.48 | Evaluation of the combined effect of NIR laser and ionizing radiation on cellular damages induced by IUdR-loaded PLGA-coated Nano-graphene oxide. ( Kargar, S; Khoee, S; Khoei, S; Mahdavi, SR; Shirvalilou, S, 2018) |
| "Rats with 9L brain tumors received intraperitoneal injections of iododeoxyuridine (IUdR) and bromodeoxyuridine (BUdR) to estimate the duration of the deoxyribonucleic acid (DNA) synthesis phase (Ts) and the potential doubling time (Tp) of individual tumors." | 1.28 | Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine. ( Asai, A; Barker, M; Gray, JW; Hoshino, T; Shibui, S; Vanderlaan, M, 1990) |
| "Prolonged treatment of glioma cells with DMSO generated a more adherent, normal human fibroblastoid phenotype that grew with contact inhibition." | 1.27 | Effect of differentiation inducers on growth characteristics of human glioma cell lines. ( Brennan, RW; Geder, L; Kreider, JW; Ladda, RL; Page, RB; Rapp, F; Towfighi, J, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 15 (57.69) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Shirvalilou, S | 2 |
| Khoei, S | 2 |
| Khoee, S | 2 |
| Mahdavi, SR | 2 |
| Raoufi, NJ | 1 |
| Motevalian, M | 1 |
| Karimi, MY | 1 |
| Kargar, S | 1 |
| Alvarez, D | 1 |
| Hogstrom, KR | 1 |
| Brown, TA | 1 |
| Ii, KL | 1 |
| Dugas, JP | 1 |
| Ham, K | 1 |
| Varnes, ME | 1 |
| Rousseau, J | 2 |
| Adam, JF | 2 |
| Deman, P | 1 |
| Wu, TD | 1 |
| Guerquin-Kern, JL | 1 |
| Gouget, B | 1 |
| Barth, RF | 1 |
| Estève, F | 2 |
| Elleaume, H | 2 |
| Wu, B | 1 |
| You, C | 1 |
| Liu, XD | 1 |
| Cai, BW | 1 |
| Biston, MC | 1 |
| Boudou, C | 1 |
| Charvet, AM | 1 |
| Balosso, J | 1 |
| Perez, LA | 1 |
| Dombkowski, D | 1 |
| Efird, J | 1 |
| Preffer, F | 1 |
| Suit, HD | 1 |
| Tjuvajev, J | 1 |
| Muraki, A | 1 |
| Ginos, J | 1 |
| Berk, J | 1 |
| Koutcher, J | 1 |
| Ballon, D | 1 |
| Beattie, B | 1 |
| Finn, R | 1 |
| Dahighian, F | 1 |
| Blasberg, R | 1 |
| Vaidyanathan, G | 2 |
| Larsen, RH | 2 |
| Zalutsky, MR | 2 |
| Williams, JA | 2 |
| Dillehay, LE | 2 |
| Tabassi, K | 1 |
| Sipos, E | 1 |
| Fahlman, C | 1 |
| Brem, H | 1 |
| Neshasteh-Riz, A | 2 |
| Mairs, RJ | 2 |
| Angerson, WJ | 2 |
| Stanton, PD | 1 |
| Reeves, JR | 2 |
| Rampling, R | 2 |
| Owens, J | 2 |
| Wheldon, TE | 1 |
| Guenther, I | 1 |
| Wyer, L | 1 |
| Knust, EJ | 1 |
| Finn, RD | 1 |
| Koziorowski, J | 1 |
| Weinreich, R | 1 |
| Wideman, CL | 1 |
| Whateley, TL | 1 |
| Reza, MS | 1 |
| Robertson, LM | 1 |
| Allan, D | 1 |
| Graham, DI | 1 |
| Yuan, X | 1 |
| Williams, JR | 1 |
| Epstein, AH | 1 |
| Cook, JA | 2 |
| Goffman, T | 1 |
| Glatstein, E | 2 |
| Maeda, T | 1 |
| Hoshino, T | 4 |
| Ito, S | 1 |
| Asai, A | 2 |
| Shibuya, M | 1 |
| Prados, MD | 1 |
| Dodson, BA | 1 |
| Davis, RL | 1 |
| Wilson, CB | 1 |
| Glass, J | 1 |
| Lebovics, R | 1 |
| Bobo, H | 1 |
| Pass, H | 1 |
| DeLaney, TF | 1 |
| Oldfield, EH | 1 |
| Mitchell, JB | 1 |
| Goffman, TE | 1 |
| Shibui, S | 2 |
| Barker, M | 1 |
| Vanderlaan, M | 2 |
| Gray, JW | 2 |
| Kassis, AI | 1 |
| Van den Abbeele, AD | 1 |
| Wen, PY | 1 |
| Baranowska-Kortylewicz, J | 1 |
| Aaronson, RA | 1 |
| DeSisto, WC | 1 |
| Lampson, LA | 1 |
| Black, PM | 1 |
| Adelstein, SJ | 1 |
| Deutsch, M | 2 |
| Rewers, AB | 2 |
| Redgate, S | 1 |
| Fisher, ER | 2 |
| Boggs, SS | 2 |
| Redgate, ES | 1 |
| Ota, A | 1 |
| Wilson, GL | 1 |
| Spilberg, O | 1 |
| Pruss, R | 1 |
| LeRoith, D | 1 |
| Geder, L | 1 |
| Kreider, JW | 1 |
| Towfighi, J | 1 |
| Page, RB | 1 |
| Ladda, RL | 1 |
| Brennan, RW | 1 |
| Rapp, F | 1 |
1 trial available for idoxuridine and Glioma
| Article | Year |
|---|---|
Tumour radiosensitization with the halogenated pyrimidines 5'-bromo- and 5'-iododeoxyuridine.
Topics: Brain Neoplasms; Bromodeoxyuridine; Glioma; Head and Neck Neoplasms; Humans; Idoxuridine; Radiation- | 1992 |
25 other studies available for idoxuridine and Glioma
| Article | Year |
|---|---|
Enhancement radiation-induced apoptosis in C6 glioma tumor-bearing rats via pH-responsive magnetic graphene oxide nanocarrier.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Liberation; Glioma; Graphite; Hydrogen-Ion C | 2020 |
Evaluation of the combined effect of NIR laser and ionizing radiation on cellular damages induced by IUdR-loaded PLGA-coated Nano-graphene oxide.
Topics: Cell Line, Tumor; Drug Carriers; Glioma; Graphite; Humans; Idoxuridine; Laser Therapy; Nanoparticles | 2018 |
Impact of IUdR on Rat 9L glioma cell survival for 25-35 keV photon-activated auger electron therapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Electrons; Glioma; Humans; Idoxuridine; Linear Energy Tran | 2014 |
Intracerebral delivery of 5-iodo-2'-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma.
Topics: Animals; Brain Neoplasms; Combined Modality Therapy; Glioma; Idoxuridine; Male; Radiation-Sensitizin | 2009 |
[Therapeutic effect of 125IUdR on the glioma cell line C6 in vitro and in vivo].
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Glioma; Idoxuridin | 2004 |
Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment.
Topics: Animals; Biophysical Phenomena; Biophysics; Brain Neoplasms; Contrast Media; Glioma; Humans; Idoxuri | 2008 |
Cell proliferation kinetics in human tumor xenografts measured with iododeoxyuridine labeling and flow cytometry: a study of heterogeneity and a comparison between different methods of calculation and other proliferation measurements.
Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; F | 1995 |
Iododeoxyuridine uptake and retention as a measure of tumor growth.
Topics: Animals; Brain Neoplasms; Glioma; Idoxuridine; Iodine Radioisotopes; Male; Rats; Rats, Inbred WF; Ra | 1993 |
5-[211 At]astato-2'-deoxyuridine, an alpha particle-emitting endoradiotherapeutic agent undergoing DNA incorporation.
Topics: Brain Neoplasms; DNA, Neoplasm; Glioma; Half-Life; Humans; Idoxuridine; Linear Energy Transfer; Tumo | 1996 |
Implantable biodegradable polymers for IUdR radiosensitization of experimental human malignant glioma.
Topics: Animals; Biodegradation, Environmental; Brain Neoplasms; Decanoic Acids; Drug Implants; Glioma; Huma | 1997 |
Cytotoxicity of alpha-particle-emitting 5-[211At]astato-2'-deoxyuridine in human cancer cells.
Topics: Alpha Particles; Antineoplastic Agents; Astatine; DNA, Neoplasm; Glioma; Humans; Idoxuridine; Iodine | 1997 |
Differential cytotoxicity of [123I]IUdR, [125I]IUdR and [131I]IUdR to human glioma cells in monolayer or spheroid culture: effect of proliferative heterogeneity and radiation cross-fire.
Topics: Cell Division; DNA; Glioma; Humans; Idoxuridine; Iodine Radioisotopes; Spheroids, Cellular; Tumor Ce | 1998 |
Radiosynthesis and quality assurance of 5-[124I]Iodo-2'-deoxyuridine for functional PET imaging of cell proliferation.
Topics: Cell Division; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glioma; Humans; Ido | 1998 |
Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model.
Topics: Animals; Brain Neoplasms; Coated Materials, Biocompatible; Drug Delivery Systems; Female; Glioma; Id | 2000 |
Synthetic, implantable polymers for IUdR radiosensitization of experimental human malignant glioma.
Topics: Animals; Bone Marrow; Brain Neoplasms; Cell Division; Decanoic Acids; Delayed-Action Preparations; D | 1999 |
[Proliferation kinetics of human brain tumors by in situ double labeling with bromodeoxyuridine and iododeoxyuridine].
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Child; Child | 1992 |
Cell kinetic analysis of human brain tumors by in situ double labelling with bromodeoxyuridine and iododeoxyuridine.
Topics: Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Glioma; Humans; Idoxuridine; Meningioma | 1992 |
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
Topics: Animals; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Flow Cytometry; Glioma; Head and Neck | 1992 |
Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; DNA, Neoplasm; Glioma; Idoxuridine; Rats; T | 1990 |
Specific uptake of the auger electron-emitting thymidine analogue 5-[123I/125I]iodo-2'-deoxyuridine in rat brain tumors: diagnostic and therapeutic implications in humans.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Line; Glioma; Humans; Idoxuridine; Iodine Radioisoto | 1990 |
Intra-cerebral ventricular infusion of 5-iodo-2-deoxyuridine (IUDR) as a radiosensitizer in the treatment of a rat glioma.
Topics: Animals; Brain Neoplasms; Death; Glioma; Idoxuridine; Injections, Intraventricular; Male; Neoplasm T | 1990 |
Double labeling with iodo- and bromodeoxyuridine for cell kinetics studies.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Glioma; Humans; Idoxuridine; Immunoenzyme Techniques; | 1989 |
5-Iodo-2-deoxyuridine administered into the lateral cerebral ventricle as a radiosensitizer in the treatment of disseminated glioma.
Topics: Animals; Cerebral Ventricle Neoplasms; Glioma; Idoxuridine; Injections, Intraventricular; Radiation- | 1989 |
Functional insulin-like growth factor I receptors are expressed by neural-derived continuous cell lines.
Topics: Animals; Cell Line; Glioma; Humans; Hybrid Cells; Idoxuridine; Insulin; Insulin-Like Growth Factor I | 1988 |
Effect of differentiation inducers on growth characteristics of human glioma cell lines.
Topics: Cell Differentiation; Cell Line; Chromosomes; Dimethyl Sulfoxide; Glioma; Humans; Idoxuridine | 1987 |