idoxuridine has been researched along with Disease Models, Animal in 38 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three hundred four animals were used for the systematic evaluation of the in vivo efficacy of 5-iodo-2'-deoxyuridine (IUDR), cytosire arabinoside, 9-beta-arabinofuranosyladenine, and isoprinosine in the therapy of herpes simplex encephalitis in an adult rat model." | 3.65 | Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model. ( Marks, MI, 1975) |
| "We treated two patients with dendritic keratitis that did not respond to acyclovir (ACV) ointment therapy." | 1.29 | Clinical characteristics of acyclovir-resistant herpetic keratitis and experimental studies of isolates. ( Inoue, Y; Kase, T; Mori, Y; Ohashi, Y; Uchihori, Y; Yao, YF, 1996) |
| "Murine cytomegalovirus was inhibited by 0." | 1.26 | Effect of cytosine arabinoside and 5-iodo-2'-deoxyuridine on a cytomegalovirus infection in newborn mice. ( Glasgow, LA; Kelsey, DK; Kern, ER; Overall, JC, 1976) |
| " The mortality rate from viral infection was significantly reduced (greater than or equal to 30%) by the following treatment regimens: cytosine arabinoside, adenine arabinoside, iododeoxyuridine, and ribavirin, administered daily for seven consecutive days starting immediately after inoculation of virus, at dosage levels of 4-20 mg/kg, 20-100mg/kg, 100mg/kg, and 20-100 mg/kg, respectively; and chlorite-oxidized oxyamylose, polyriboinosinic-polyribocytidylic acid, and mouse interferon, administered 24 hr before viral challenge, as single doses of 100-500 mg/kg, 20mg/kg, and 10(7)-10(8) international reference units/kg respectively." | 1.26 | Intranasal challenge of mice with herpes simplex virus: an experimental model for evaluation of the efficacy of antiviral drugs. ( De Clercq, E; Luczak, M, 1976) |
| " The validity of therapy with either of these drugs in generalized herpetic infections is questioned because activity was minimal against the infecting agent even when the dosage of the drug was sufficient to produce serious defects in certain developing tissues." | 1.25 | Experimental infection with herpes simplex virus type 2 in newborn rats: Effects of treatment with iododeoxyuridine and cytosine arabinoside. ( Hatch, LA; Percy, DH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (84.21) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 2 (5.26) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Opendak, M | 1 |
| Offit, L | 1 |
| Monari, P | 1 |
| Schoenfeld, TJ | 1 |
| Sonti, AN | 1 |
| Cameron, HA | 1 |
| Gould, E | 1 |
| Salmaso, N | 1 |
| Silbereis, J | 1 |
| Komitova, M | 1 |
| Mitchell, P | 1 |
| Chapman, K | 1 |
| Ment, LR | 1 |
| Schwartz, ML | 1 |
| Vaccarino, FM | 1 |
| Plummer, G | 1 |
| Ingerson, AP | 1 |
| Park, NH | 1 |
| Pavan-Langston, D | 1 |
| Hettinger, ME | 1 |
| Geary, PA | 1 |
| August, ML | 1 |
| Albert, DM | 1 |
| Lin, TS | 1 |
| Prusoff, WH | 1 |
| Dunn, DL | 1 |
| Barke, RA | 1 |
| Lee, JT | 1 |
| Condie, RM | 1 |
| Humphrey, EW | 1 |
| Simmons, RL | 1 |
| Colin, C | 1 |
| Chastel, C | 1 |
| Quillien, MC | 1 |
| Renard, G | 1 |
| Pollack, A | 1 |
| Terry, NH | 1 |
| White, RA | 1 |
| Cao, S | 1 |
| Meistrich, ML | 1 |
| Milas, L | 1 |
| Yao, YF | 1 |
| Inoue, Y | 1 |
| Kase, T | 1 |
| Uchihori, Y | 1 |
| Mori, Y | 1 |
| Ohashi, Y | 1 |
| Dupertuis, YM | 1 |
| Xiao, WH | 1 |
| De Tribolet, N | 1 |
| Pichard, C | 1 |
| Slosman, DO | 1 |
| Bischof Delaloye, A | 1 |
| Buchegger, F | 1 |
| Kaufman, HE | 3 |
| Marks, MI | 1 |
| Percy, DH | 1 |
| Hatch, LA | 1 |
| Kelsey, DK | 1 |
| Kern, ER | 2 |
| Overall, JC | 2 |
| Glasgow, LA | 3 |
| Nesburn, AB | 2 |
| Alford, CA | 1 |
| Whitley, RJ | 1 |
| De Clercq, E | 1 |
| Luczak, M | 1 |
| Harris, SR | 1 |
| Boyd, MR | 1 |
| Worthington, M | 1 |
| Conliffe, M | 1 |
| Collins, P | 1 |
| Bauer, DJ | 1 |
| Cavanagh, HD | 1 |
| el-Sahn, MF | 1 |
| Korra, AK | 1 |
| Abou-Shousha, EK | 1 |
| Hyndiuk, RA | 1 |
| Okumoto, M | 1 |
| Damiano, RA | 1 |
| Valenton, M | 1 |
| Smolin, G | 1 |
| Okuyama, S | 1 |
| Sato, T | 1 |
| Takahashi, K | 1 |
| Ito, Y | 1 |
| Matsuzawa, T | 1 |
| Schackert, G | 1 |
| Fidler, IJ | 1 |
| Cobb, RA | 1 |
| Steer, HW | 1 |
| Varnell, ED | 1 |
| Hofer, KG | 1 |
| DiBenedetto, J | 1 |
| Hughes, WL | 1 |
| Easterbrook, M | 1 |
| Wilkie, J | 1 |
| Coleman, V | 1 |
| Dawson, CR | 1 |
| Panitch, HS | 1 |
| Baringer, JR | 1 |
| Cho, CT | 1 |
| Liu, C | 1 |
| Voth, DW | 1 |
| Feng, KK | 1 |
| Robinson, C | 1 |
| Dickinson, R | 1 |
| Dauphinee, MJ | 1 |
| Talal, N | 1 |
| Goldstein, AL | 1 |
| White, A | 1 |
| Poste, G | 1 |
| Hawkins, DF | 1 |
| Thomlinson, J | 1 |
| McFadzean, JA | 1 |
6 reviews available for idoxuridine and Disease Models, Animal
| Article | Year |
|---|---|
Herpetic keratitis. Proctor Lecture.
Topics: Adrenal Cortex Hormones; Animals; Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry | 1978 |
Recurrence in ocular herpes simplex infection.
Topics: Animals; Antibodies, Viral; Disease Models, Animal; Disease Reservoirs; Humans; Idoxuridine; Interfe | 1975 |
Treatment of infections due to Herpesvirus in humans: a critical review of the state of the art.
Topics: Administration, Topical; Animals; Antiviral Agents; Disease Models, Animal; Herpes Simplex; Herpes Z | 1976 |
Herpetic ocular disease: therapy of persistent epithelial defects.
Topics: Adrenal Cortex Hormones; Animals; Anti-Infective Agents, Local; Antigens, Viral; Cell Division; Dise | 1975 |
Herpesvirus hominis infection of the female genital tract.
Topics: Antigens, Viral; Bacterial Infections; Candidiasis, Vulvovaginal; Diagnosis, Differential; Disease M | 1972 |
Advances in the chemotherapy of viral diseases.
Topics: Amantadine; Animals; Antiviral Agents; Disease Models, Animal; Humans; Idoxuridine; Models, Biologic | 1969 |
32 other studies available for idoxuridine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Lasting Adaptations in Social Behavior Produced by Social Disruption and Inhibition of Adult Neurogenesis.
Topics: Adaptation, Psychological; Animals; Anxiety; Disease Models, Animal; Glial Fibrillary Acidic Protein | 2016 |
Environmental enrichment increases the GFAP+ stem cell pool and reverses hypoxia-induced cognitive deficits in juvenile mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Differentiation | 2012 |
Iododeoxyuridine and herpesviral encephalitis: lack of inhibitory action against low-grade viral replication.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Encephalitis, Herpes Simplex; Humans; Idoxuridine | 1974 |
Development of oral HSV-1 infection model in mice. Evaluation of efficacy of 5'-amino-5-iodo-2',5'-dideoxyuridine.
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Idoxuridine; Lip; Male; Mice; Mice, I | 1982 |
Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. VII. Hemoglobin does not inhibit clearance of Escherichia coli from the peritoneal cavity.
Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Hemoglobins; Humans; | 1983 |
[Comparison of therapeutic activity of idoxuridine and acyclovir in experimentally-induced herpetic keratitis in rabbits (author's transl)].
Topics: Acyclovir; Animals; Antiviral Agents; Cornea; Disease Models, Animal; Female; Guanine; Idoxuridine; | 1981 |
Proliferation kinetics of recruited cells in a mouse mammary carcinoma.
Topics: Animals; Cell Cycle; Cell Division; Deoxyuridine; Disease Models, Animal; DNA, Neoplasm; Flow Cytome | 1994 |
Clinical characteristics of acyclovir-resistant herpetic keratitis and experimental studies of isolates.
Topics: Acyclovir; Administration, Topical; Adult; Animals; Antiviral Agents; Cornea; Culture Techniques; Di | 1996 |
Unlabelled iododeoxyuridine increases the rate of uptake of [125I]iododeoxyuridine in human xenografted glioblastomas.
Topics: Animals; Cell Cycle; Disease Models, Animal; DNA, Neoplasm; Glioblastoma; Humans; Idoxuridine; In Vi | 2002 |
Evaluation of four antiviral agents in the treatment of herpes simplex encephalitis in a rat model.
Topics: Acetanilides; Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cell Line; Culture Techniques; C | 1975 |
Experimental infection with herpes simplex virus type 2 in newborn rats: Effects of treatment with iododeoxyuridine and cytosine arabinoside.
Topics: Animals; Animals, Newborn; Cytarabine; Disease Models, Animal; Herpesviridae Infections; Idoxuridine | 1975 |
Effect of cytosine arabinoside and 5-iodo-2'-deoxyuridine on a cytomegalovirus infection in newborn mice.
Topics: Animals; Animals, Newborn; Cell Line; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Disea | 1976 |
Intranasal challenge of mice with herpes simplex virus: an experimental model for evaluation of the efficacy of antiviral drugs.
Topics: Animals; Antiviral Agents; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Encepha | 1976 |
Advantages and limitations of animal models in the evaluation of antiviral substances.
Topics: Amantadine; Animals; Antiviral Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; | 1976 |
The activity of iododeoxyuridine, adenine arabinoside, cytosine arabinoside, ribavirin and phosphonoacetic acid against herpes virus in the hairless mouse model.
Topics: Acetates; Animals; Cytarabine; Disease Models, Animal; Herpes Simplex; Idoxuridine; Kinetics; Mice; | 1977 |
Treatment of fatal disseminated vaccinia virus infection in immunosuppressed mice.
Topics: Animals; Antilymphocyte Serum; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Ido | 1977 |
Comparison of activity of herpes virus inhibitors.
Topics: Animals; Antiviral Agents; Cytarabine; Disease Models, Animal; Drug Evaluation, Preclinical; Herpes | 1977 |
Ocular antiviral therapy in perspective.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Ulcer; Cytarabine; Disease Models, Animal; Dos | 1976 |
Evaluation of some lines of therapy in experimentally induced herpetic keratitis in rabbits.
Topics: Animals; Cautery; Corneal Transplantation; Cryosurgery; Debridement; Disease Models, Animal; Edetic | 1976 |
Treatment of vaccinial keratitis with vidarabine.
Topics: Animals; Corneal Ulcer; Disease Models, Animal; Fluoresceins; Idoxuridine; Keratitis; Purine Nucleos | 1976 |
Isolated marrow reticuloendothelial activation and erythropoietic response following an acute blood loss.
Topics: Acute Disease; Anemia; Animals; Bloodletting; Bone Marrow; Chondroitin; Colloids; Disease Models, An | 1975 |
Development of in vivo models for studies of brain metastasis.
Topics: Animals; Brain; Brain Neoplasms; Carotid Arteries; Disease Models, Animal; Female; Idoxuridine; Iodi | 1988 |
Tumour cell trapping in rat mesenteric lymph nodes.
Topics: Animals; Autoradiography; Disease Models, Animal; Idoxuridine; Iodine Radioisotopes; Lung Neoplasms; | 1987 |
Photodynamic inactivation with proflavine: quantitative comparison with iodo-deoxyuridine.
Topics: Animals; Disease Models, Animal; Flavins; Fluoresceins; Idoxuridine; Keratitis, Dendritic; Light; Ra | 1973 |
Natural and asparaginase induced death of L5178Y leukemia cells in vivo.
Topics: Animals; Asparaginase; Disease Models, Animal; Idoxuridine; Iodine Isotopes; Leukemia, Experimental; | 1970 |
The effect of topical corticosteroids on the susceptibility of immune animals to reinoculation with Herpes simplex.
Topics: Animals; Dexamethasone; Disease Models, Animal; Idoxuridine; Keratitis, Dendritic; Male; Methods; Oi | 1973 |
Experimental herpes simplex encephalitis. Treatment with pyrimidine nucleosides.
Topics: Animals; Brain Stem; Cytarabine; Disease Models, Animal; Encephalitis; Hemorrhage; Herpes Simplex; H | 1973 |
Herpesvirus hominis infection in newborn mice. I. An experimental model and therapy with iododeoxyuridine.
Topics: Animals; Cells, Cultured; Central Nervous System; Disease Models, Animal; Herpesviridae Infections; | 1973 |
Effects of idoxuridine on Herpesvirus hominis encephalitis and disseminated infections in marmosets.
Topics: Animals; Antibodies; Disease Models, Animal; Encephalitis; Haplorhini; Herpes Simplex; Idoxuridine; | 1973 |
Adenine arabinoside effect on experimental idoxuridine-resistant herpes simplex infection.
Topics: Adenine; Animals; Disease Models, Animal; Drug Resistance, Microbial; Idoxuridine; Keratitis, Dendri | 1974 |
Thymosin corrects the abnormal DNA synthetic response of NZB mouse thymocytes.
Topics: Age Factors; Animals; Autoimmune Diseases; Cell Differentiation; Cell Division; Chromium Radioisotop | 1974 |