idoxuridine and Corneal Ulcer studies

Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.

Research Excerpts

Excerpt	Relevance	Reference
"Thus, we found that the role of Acyclovir in the treatment of viral corneal ulcer is definitely better and quicker."	9.06	Comparative study of acyclovir and 5 I.D.U. in the management of viral corneal ulcer. ( Bist, HK; Kumar, S; Satsangi, SK; Singh, YP, 1987)
"The treatment of herpetic corneal ulcerations with trifluorthymidine (F3T) has been evaluated in a clinical trial."	9.05	Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation. ( Gilbert, P; Work, K, 1980)
"Thus, we found that the role of Acyclovir in the treatment of viral corneal ulcer is definitely better and quicker."	5.06	Comparative study of acyclovir and 5 I.D.U. in the management of viral corneal ulcer. ( Bist, HK; Kumar, S; Satsangi, SK; Singh, YP, 1987)
"The treatment of herpetic corneal ulcerations with trifluorthymidine (F3T) has been evaluated in a clinical trial."	5.05	Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation. ( Gilbert, P; Work, K, 1980)
"In a coded study, we treated 40 patients who had active herpes simplex corneal ulcers with either 1% trifluorothymidine (F3T) or 0."	5.04	Trifluorothymidine and idoxuridine therapy of ocular herpes. ( Foster, CS; Pavan-Langston, D, 1977)
"Herpes simplex keratitis is a major cause of corneal scarring in Africa."	1.28	Herpetic keratitis in Tanzania: association with malaria. ( Foster, A; Yorston, D, 1992)

Timeframe	Studies, this research(%)	All Research%
pre-1990	53 (92.98)	18.7374
1990's	3 (5.26)	18.2507
2000's	1 (1.75)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
SWARTZ, J	1
KAUFMAN, HE	7
HEIDELBERGER, C	1
MACKENZIE, AD	1
CROMPTON, DO	1
WOLLENSAK, J	1
KYPKE, W	1
GORDON, DM	1
ADVOCATE, S	1
HANNA, C	1
WILKINSON, KP	1
THOMAS, CI	1
PURNELL, EW	1
ROSENTHAL, MS	1
Lanier, JD	1
Whitcher, JP	1
Dawson, CR	2
Oh, JO	1
Ledbetter, EC	1
Riis, RC	1
Kern, TJ	1
Haley, NJ	1
Schatzberg, SJ	1
Gilbert, P	1
Work, K	1
Coster, DJ	3
Wilhelmus, KR	1
Michaud, R	1
Jones, BR	8
Collum, LM	1
Benedict-Smith, A	1
Hillary, IB	1
Maudgal, PC	2
De Kimpe, N	1
De Clercq, E	1
Descamps, J	1
Missotten, L	2
Geysen, A	1
Poirier, RH	2
Smith, JS	1
Pavan-Langston, D	2
Stanley, JA	1
Pinnolis, M	1
McGill, J	3
Foster, CS	1
Shiota, H	1
Inoue, S	1
Yamane, S	1
Van Deuren, H	1
Falcon, MG	1
Cantell, K	1
Hyndiuk, RA	1
Okumoto, M	1
Damiano, RA	1
Valenton, M	1
Smolin, G	1
Laibson, PR	1
Hyndiuk, R	1
Krachmer, JH	1
Schultz, RO	1
O'Day, DM	1
Jones, DB	1
Elliott, JH	1
Yorston, D	1
Foster, A	1
Denis, J	1
Chouraqui, P	1
Karpouzas, I	1
Hoang-Xuan, T	1
Pouliquen, Y	1
Kumar, S	1
Singh, YP	1
Satsangi, SK	1
Bist, HK	1
Naginton, J	1
Watson, PG	1
Playfair, TJ	1
Steele, AD	1
Pietruschka, G	1
Centifanto, Y	1
Böke, W	1
de Decker, W	1
White, DO	1
Shew, MA	1
Howsam, KG	1
Robertson, IF	1
Bistner, SI	1
Carlson, JH	1
Shively, JN	1
Scott, FW	1
Austin, DJ	1
Walker, WM	1
DeVoe, AG	2
Wellings, PC	1
Awdry, PN	1
Bors, FH	1
Brown, DC	1
Williams, H	1
McKinnon, J	1
Holt-Wilson, AD	1
Koch, SA	1
Patterson, A	1
Maumenee, AE	1
el-Massri, A	1
François, P	1
Roberts, SR	1
Coleman, V	1
Togni, B	1
Frederique, G	1
Howard, RO	1
Boniuk, V	1
Abboud, I	1
Milverton, EJ	1
Hunyor, AB	1
Reim, M	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Retrospective Study of the in Vivo Confocal Microscopic Findings and the Treatment Outcome of Acanthamoebic Keratitis[NCT02763605]				100 participants (Anticipated)	Observational	2014-01-31	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Herpetic keratitis. Proctor Lecture. Investigative ophthalmology & visual science, 1978, Volume: 17, Issue:10 Topics: Adrenal Cortex Hormones; Animals; Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry	1978
Diagnosis and management of herpes simplex ocular infection. International ophthalmology clinics, 1975,Winter, Volume: 15, Issue:4 Topics: Administration, Topical; Adolescent; Anti-Bacterial Agents; Child, Preschool; Corneal Ulcer; Debride	1975
The practical management of ocular infections. II. Viral infections. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1972, Volume: 7, Issue:1 Topics: Amantadine; Antifungal Agents; Corneal Transplantation; Corneal Ulcer; Epithelium; Eye Diseases; Her	1972
Ocular virus disease. Annals of clinical research, 1973, Volume: 5, Issue:4 Topics: Adenine; Adolescent; Chickenpox; Child; Child, Preschool; Chorioretinitis; Conjunctivitis; Corneal U	1973

Article	Year
Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation. Acta ophthalmologica, 1980, Volume: 58, Issue:1 Topics: Chemical Phenomena; Chemistry; Clinical Trials as Topic; Corneal Ulcer; Herpes Simplex; Humans; Idox	1980
A comparison of acyclovir and idoxuridine as treatment for ulcerative herpetic keratitis. The British journal of ophthalmology, 1980, Volume: 64, Issue:10 Topics: Acyclovir; Clinical Trials as Topic; Corneal Ulcer; Double-Blind Method; Guanine; Humans; Idoxuridin	1980
Randomised double-blind trial of acyclovir and idoxuridine in dendritic corneal ulceration. The British journal of ophthalmology, 1980, Volume: 64, Issue:10 Topics: Acyclovir; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Corneal Ulcer	1980
Trifluorothymidine and idoxuridine therapy of ocular herpes. American journal of ophthalmology, 1977, Volume: 84, Issue:6 Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Clinical Trials a	1977
Clinical trials of topical interferon therapy of ulcerative viral keratitis. The Journal of infectious diseases, 1976, Volume: 133 Suppl Topics: Administration, Topical; Animals; Clinical Trials as Topic; Corneal Ulcer; Debridement; Drug Evaluat	1976
Ara-A and IDU therapy of human superficial herpetic keratitis. Investigative ophthalmology, 1975, Volume: 14, Issue:10 Topics: Clinical Trials as Topic; Corneal Ulcer; Glaucoma; Humans; Idoxuridine; Keratitis; Keratitis, Dendri	1975
[Treatment of superficial herpes simplex keratitis with vidarabine (Vira A): multicenter study of 100 cases]. Journal francais d'ophtalmologie, 1990, Volume: 13, Issue:3 Topics: Adult; Antiviral Agents; Bromodeoxycytidine; Corneal Ulcer; Deoxycytidine; Drug Resistance; Female;	1990
Comparative study of acyclovir and 5 I.D.U. in the management of viral corneal ulcer. Indian journal of ophthalmology, 1987, Volume: 35, Issue:5-6 Topics: Acyclovir; Corneal Ulcer; Humans; Idoxuridine; Virus Diseases	1987
Clinical evaluation of trifluorothymidine in the treatment of herpes simplex corneal ulcers. American journal of ophthalmology, 1972, Volume: 73, Issue:6 Topics: Antiviral Agents; Clinical Trials as Topic; Corneal Ulcer; Fluorine; Humans; Idoxuridine; Keratitis,	1972
Reassessment of idoxuridine therapy of herpetic keratitis. Transactions of the ophthalmological societies of the United Kingdom, 1974, Volume: 94, Issue:2 Topics: Clinical Trials as Topic; Conjunctivitis; Corneal Ulcer; Dermatitis, Contact; Eyelid Diseases; Human	1974
The management of ocular herpes. Transactions of the ophthalmological societies of the United Kingdom, 1967, Volume: 87 Topics: Adolescent; Adult; Aged; Burns, Chemical; Cautery; Child; Child, Preschool; Clinical Trials as Topic	1967

idoxuridine and Corneal Ulcer

Research Excerpts

Research

Studies (57)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Article	Year
Report on 36 patients with dendritic corneal ulceration treated with IDU ('stoxil'). South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1963, May-25, Volume: 37 Topics: Corneal Ulcer; Humans; Idoxuridine; Keratitis; Keratitis, Dendritic	1963
THERAPEUTIC ANTIVIRAL ACTION OF 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE IN HERPES SIMPLEX KERATITIS. Science (New York, N.Y.), 1964, Aug-07, Volume: 145, Issue:3632 Topics: Animals; Antiviral Agents; Cornea; Corneal Ulcer; Idoxuridine; Keratitis; Keratitis, Dendritic; Kera	1964
A COMPARISON OF IDU SOLUTION, IDU OINTMENT, AND CARBOLIZATION IN THE TREATMENT OF DENDRITIC CORNEAL ULCER. The British journal of ophthalmology, 1964, Volume: 48 Topics: Cornea; Corneal Ulcer; Humans; Idoxuridine; Keratitis; Keratitis, Dendritic; Keratitis, Herpetic; Oi	1964
TREATMENT OF VIRAL DISEASE. International ophthalmology clinics, 1964, Volume: 4 Topics: Cautery; Corneal Ulcer; Curettage; Drug Therapy; Humans; Idoxuridine; Keratitis; Keratitis, Dendriti	1964
CORTICOSTEROIDS EXACERBATE OCULAR HERPES SIMPLEX. The Medical journal of Australia, 1964, Dec-12, Volume: 2 Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Betamethasone; Corneal Ulcer; Drug The	1964
[INHIBITION OF EPITHELIAL REGENERATION AND CORNEAL WOUND HEALING IN RABBITS BY ANTIMETABOLITES]. Albrecht von Graefe's Archiv fur Ophthalmologie, 1965, Feb-05, Volume: 168 Topics: Animals; Antimetabolites; Cornea; Corneal Ulcer; Cortisone; Epithelium; Idoxuridine; Ointments; Phar	1965
VACCINIAL BLEPHAROKERATITIS TREATED WITH CYTOSINE ARABINOSIDE. American journal of ophthalmology, 1965, Volume: 59 Topics: Antiviral Agents; Corneal Ulcer; Cytarabine; Cytosine; Drug Therapy; Eyelids; Humans; Idoxuridine; I	1965
EFFECT OF IDOXURIDINE ON THE UPTAKE OF TRITIUM-LABELED THYMIDINE IN THE RABBIT CORNEA INFECTED WITH HERPES SIMPLEX. Experimental eye research, 1965, Volume: 4 Topics: Animals; Cornea; Corneal Ulcer; DNA; DNA, Viral; Epithelium; Herpes Simplex; Idoxuridine; Keratitis;	1965
TREATMENT OF HERPETIC KERATITIS WITH IDU AND CORTICOSTEROIDS; REPORT OF 105 CASES. American journal of ophthalmology, 1965, Volume: 60 Topics: Adrenal Cortex Hormones; Corneal Ulcer; Drug Therapy; Humans; Hypersensitivity; Idoxuridine; Iritis;	1965
Proflavine and light in the treatment of experimental herpetic ocular infections. Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:5 Topics: Animals; Corneal Ulcer; Drug Therapy, Combination; Idoxuridine; Keratitis, Herpetic; Male; Photochem	1974
Corneal ulceration associated with naturally occurring canine herpesvirus-1 infection in two adult dogs. Journal of the American Veterinary Medical Association, 2006, Aug-01, Volume: 229, Issue:3 Topics: Animals; Antiviral Agents; Corneal Ulcer; Dog Diseases; Dogs; Female; Herpesviridae Infections; Herp	2006
Management of herpetic keratitis. Transactions of the Ophthalmological Society of New Zealand, 1982, Volume: 34 Topics: Antiviral Agents; Corneal Transplantation; Corneal Ulcer; Debridement; Female; Humans; Idoxuridine;	1982
Influence of (E)-5-(2-bromovinyl)-2'-deoxyuridine on corneal epithelium healing. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1982, Volume: 218, Issue:5 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cornea; Corneal Ulcer; Epithelium; Eye Injuries; Idoxu	1982
Herpetic ocular infections of childhood. Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:4 Topics: Adolescent; Atropine; Child; Child, Preschool; Corneal Ulcer; Drug Resistance, Microbial; Female; Fo	1980
Ocular discharge and eyelid spasm in a kitten. Australian veterinary journal, 1999, Volume: 77, Issue:9 Topics: Animals; Antiviral Agents; Cat Diseases; Cats; Conjunctivitis, Viral; Cornea; Corneal Ulcer; Eyelid	1999
Light intensity on the photodynamic inactivation of herpes simplex keratitis. American journal of ophthalmology, 1976, Volume: 81, Issue:3 Topics: Animals; Color; Corneal Ulcer; Drug Resistance, Microbial; Fluorescence; Idoxuridine; Keratitis, Den	1976
Drug resistance and antiviral agents. The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:3 Topics: Corneal Ulcer; Drug Resistance, Microbial; Herpesviridae Infections; Humans; Idoxuridine; Keratitis,	1977
Efficacy of acycloguanosine against herpetic ulcers in rabbit cornea. The British journal of ophthalmology, 1979, Volume: 63, Issue:6 Topics: Animals; Corneal Ulcer; Guanosine; Idoxuridine; Keratitis, Dendritic; Rabbits	1979
Therapeutic effect of corneal replicas in herpetic keratitis. Bulletin de la Societe belge d'ophtalmologie, 1979, Volume: 185 Topics: Corneal Opacity; Corneal Ulcer; Follow-Up Studies; Humans; Idoxuridine; Keratitis, Dendritic; Method	1979
Ocular antiviral therapy in perspective. The Journal of infectious diseases, 1976, Volume: 133 Suppl Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Ulcer; Cytarabine; Disease Models, Animal; Dos	1976
The need for antiviral therapy and prophylaxis of viral ocular disease. The Journal of infectious diseases, 1976, Volume: 133 Suppl Topics: Antiviral Agents; Corneal Ulcer; Costs and Cost Analysis; Humans; Idoxuridine; Keratitis, Dendritic;	1976
Treatment of vaccinial keratitis with vidarabine. Archives of ophthalmology (Chicago, Ill. : 1960), 1976, Volume: 94, Issue:8 Topics: Animals; Corneal Ulcer; Disease Models, Animal; Fluoresceins; Idoxuridine; Keratitis; Purine Nucleos	1976
Vidarabine therapy of complicated herpes simplex keratitis. American journal of ophthalmology, 1976, Volume: 81, Issue:5 Topics: Adrenal Cortex Hormones; Corneal Ulcer; Drug Administration Schedule; Drug Resistance, Microbial; Dr	1976
Herpetic keratitis in Tanzania: association with malaria. The British journal of ophthalmology, 1992, Volume: 76, Issue:10 Topics: Adolescent; Adult; Child; Child, Preschool; Corneal Ulcer; Female; Humans; Idoxuridine; Infant; Kera	1992
Amoebic infection of the eye. Lancet (London, England), 1974, Dec-28, Volume: 2, Issue:7896 Topics: Adrenal Cortex Hormones; Adult; Amebiasis; Amoeba; Anti-Bacterial Agents; Blindness; Cornea; Corneal	1974
[Epicritical consideration on the severe course of herpetic keratitis]. Klinische Monatsblatter fur Augenheilkunde, 1968, Volume: 153, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; Antiviral Agents; Blindness; Chlortetracycline; Corneal Transpla	1968
Thymidine kinase in IDU resistance. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:1 Topics: Animals; Chromatography, Paper; Corneal Ulcer; Drug Resistance, Microbial; Fibroblasts; Idoxuridine;	1965
[On the differential diagnosis of keratitis]. Klinische Monatsblatter fur Augenheilkunde, 1966, Volume: 149, Issue:4 Topics: Adrenal Cortex Hormones; Antifungal Agents; Colistin; Corneal Ulcer; Diagnosis, Differential; Herpes	1966
Herpes simplex virus infection of the cornea. The Medical journal of Australia, 1968, Jul-13, Volume: 2, Issue:2 Topics: Corneal Ulcer; Humans; Idoxuridine; Keratitis, Dendritic; Neomycin; Simplexvirus	1968
Ocular manifestations of feline herpesvirus infection. Journal of the American Veterinary Medical Association, 1971, Volume: 159, Issue:10 Topics: Animals; Cat Diseases; Cats; Corneal Ulcer; Hemagglutination Inhibition Tests; Herpesviridae Infecti	1971
Idoxuridine and iodization in the treatment of simple dendritic ulceration. Transactions of the ophthalmological societies of the United Kingdom, 1974, Volume: 94, Issue:2 Topics: Corneal Ulcer; Humans; Idoxuridine; Iodine; Keratitis, Dendritic	1974
Ulcerative keratitis. The Veterinary clinics of North America, 1973, Volume: 3, Issue:3 Topics: Anesthetics, Dissociative; Anesthetics, Local; Animals; Anti-Bacterial Agents; Candidiasis; Cat Dise	1973
Management of chronic corneal ulcers. Southern medical journal, 1969, Volume: 62, Issue:10 Topics: Amphotericin B; Chronic Disease; Contact Lenses; Corneal Transplantation; Corneal Ulcer; Epithelium;	1969
Medical therapy of corneal disease. International ophthalmology clinics, 1970,Summer, Volume: 10, Issue:2 Topics: Antifungal Agents; Contact Lenses; Cornea; Corneal Transplantation; Corneal Ulcer; Edema; Eye Diseas	1970
New concepts in the treatment of the dendritic ulcer. Bulletin of the Ophthalmological Society of Egypt, 1970, Volume: 63, Issue:67 Topics: Cautery; Corneal Transplantation; Corneal Ulcer; Humans; Idoxuridine; Keratitis, Dendritic; Methods;	1970
[Superficial herpetic keratitis]. L'Annee therapeutique et clinique en ophtalmologie, 1971, Volume: 22 Topics: Antiviral Agents; Cornea; Corneal Transplantation; Corneal Ulcer; Cryosurgery; Cytarabine; Herpes Zo	1971
Dendritic keratitis in a cat. Journal of the American Veterinary Medical Association, 1972, Aug-01, Volume: 161, Issue:3 Topics: Animals; Cat Diseases; Cats; Corneal Ulcer; Herpesviridae; Idoxuridine; Keratitis, Dendritic; Micros	1972
Prospects in treating viral disease of the eye. Transactions of the ophthalmological societies of the United Kingdom, 1967, Volume: 87 Topics: Animals; Antiviral Agents; Corneal Ulcer; Eye Diseases; Glucocorticoids; Humans; Idoxuridine; Rabbit	1967
Corneal ulcers in rubeola. American journal of ophthalmology, 1969, Volume: 68, Issue:6 Topics: Anti-Bacterial Agents; Atropine; Child; Child, Preschool; Corneal Opacity; Corneal Ulcer; Disease Ou	1969
Evaluation of I.D.U. in the treatment of dendritic ulcer. Bulletin of the Ophthalmological Society of Egypt, 1967, Volume: 60, Issue:64 Topics: Animals; Corneal Ulcer; Humans; Idoxuridine; Keratitis, Dendritic	1967
Cryotherapy for dendritic keratitis. The Medical journal of Australia, 1969, May-03, Volume: 1, Issue:18 Topics: Corneal Ulcer; Corticosterone; Cryosurgery; Eyelids; Follow-Up Studies; Hot Temperature; Humans; Ido	1969
[Observations during the treatment of dendritic keratitis with 5-iodouracil 2-desoxyriboside (IUDR)]. Klinische Monatsblatter fur Augenheilkunde, 1965, Volume: 147, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Corneal Ulcer; Fundus Oculi; Humans; Idoxurid	1965