Page last updated: 2024-11-07

idoxuridine and Colonic Neoplasms

idoxuridine has been researched along with Colonic Neoplasms in 28 studies

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"To detect and quantify hypoxia in colorectal adenocarcinomas by use of pimonidazole and iododeoxyuridine (IdUrd) as extrinsic markers and carbonic anhydrase IX (CA IX), microvessel density (MVD), epidermal growth-factor receptor (EGFR), and vascular endothelial growth factor (VEGF) as intrinsic markers of hypoxia."3.73Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers. ( Begg, AC; De Schutter, H; Debucquoy, A; Ectors, N; Geboes, K; Goethals, L; Haustermans, KM; McBride, WH; Penninckx, F; Perneel, C, 2006)
"The prognosis of colorectal cancer has not significantly changed during the last 30 years."1.30Systematic heterogeneity and prognostic significance of cell proliferation in colorectal cancer. ( Bergström, C; Oberg, A; Palmqvist, R; Rutegård, JN; Stenling, R; Zackrisson, B, 1998)
" Pharmacokinetic analysis of p."1.29An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116. ( Cheng, YC; Kinsella, TJ; Kunugi, KA; Liu, SH; McCulloch, W; Vielhuber, KA, 1994)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.29)18.7374
1990's17 (60.71)18.2507
2000's7 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berry, SE1
Loh, T1
Yan, T1
Kinsella, TJ6
Shin, JH1
Chung, JK1
Kang, JH1
Lee, YJ1
Kim, KI1
Kim, CW1
Jeong, JM1
Lee, DS1
Lee, MC1
Chi, KH1
Wang, HE1
Wang, YS1
Chou, SL1
Yu, HM1
Tseng, YH1
Hwang, IM1
Lui, WY1
Schaffland, AO1
Delaloye, AB1
Kosinski, M1
Dupertuis, YM1
Buchegger, F2
Coucke, PA1
Cottin, E1
Azria, D1
Martineau, P1
Adamer, F1
Decosterd, LA1
Do, HP1
Baranowska-Kortylewicz, J2
Nearman, J1
Goethals, L1
Debucquoy, A1
Perneel, C1
Geboes, K1
Ectors, N1
De Schutter, H1
Penninckx, F1
McBride, WH1
Begg, AC1
Haustermans, KM1
Kunugi, KA2
Vielhuber, KA1
McCulloch, W1
Liu, SH1
Cheng, YC1
Rodriguez, R2
Ritter, MA1
Fowler, JF3
Kortylewicz, ZP1
Hoffman, D1
Winoto, A1
Lai, J1
Dalrymple, GV1
Palmqvist, R1
Oberg, A1
Bergström, C1
Rutegård, JN1
Zackrisson, B1
Stenling, R1
Glennon, MC1
Lindstrom, MJ1
Fritze, D1
Kern, DH1
Drogemuller, CR1
Pilch, YH1
Birchall, JP1
Owen, JJ1
Miller, MA2
Bokhari, SA1
Qadir, K1
Raza, A2
Miller, EM1
Lawrence, TS3
Davis, MA3
Maybaum, J3
Stetson, PL3
Ensminger, WD3
McKeever, PE1
Normolle, DP1
Kelly, SA1
Gschmeissner, S1
East, N1
Balkwill, FR1
Pedley, RB2
Begent, RH1
Boden, JA2
Boden, R1
Adam, T1
Bagshawe, KD3
Sharma, K1
Southall, PJ1
Boxer, GM1
Patridge, TA1
Antoniw, P1
Humm, JL1
Sharma, SK1
Boxer, G1
Mazewski, CM1
Yousuf, N1
Sheikh, Y1
White, LM1
Yanik, GA1
Hyams, DM1
Lampkin, BC1
Miller, E1
Calabresi, P1
Curt, G1
Okubo, A1
Sone, S1
Tanaka, M1
Ogura, T1
Shearer, WT1
Philpott, GW1
Parker, CW1

Other Studies

28 other studies available for idoxuridine and Colonic Neoplasms

ArticleYear
Role of MutSalpha in the recognition of iododeoxyuridine in DNA.
    Cancer research, 2003, Sep-01, Volume: 63, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Base Pair Mismatch; Carrier Proteins; Cell Nucleus; Colonic Ne

2003
Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk.
    European journal of nuclear medicine and molecular imaging, 2004, Volume: 31, Issue:3

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Colonic Neoplasms; Feasibility Studies; Gene Expressio

2004
Antisense thymidylate synthase electrogene transfer to increase uptake of radiolabeled iododeoxyuridine in a murine model.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:3

    Topics: Adenocarcinoma; Animals; BALB 3T3 Cells; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA, Antis

2004
The preparation of clinical grade 5-[123I]iodo-2'-deoxyuridine and 5-[125I]iodo-2'-deoxyuridine with high in vitro stability and the potential for early proliferation scintigraphy.
    Nuclear medicine communications, 2004, Volume: 25, Issue:5

    Topics: Animals; Cell Division; Colonic Neoplasms; Feasibility Studies; Female; Humans; Idoxuridine; Iodine

2004
Positive interactive radiosensitisation in vitro with the combination of two nucleoside analogues, (E)-2'-deoxy-2'-(fluoromethylene) cytidine and iododeoxyuridine.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Deoxycytidine;

2004
DNA uptake of 131I-iododeoxyuridine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:5

    Topics: Adenocarcinoma; Animals; BALB 3T3 Cells; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA, Antis

2005
Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.
    International journal of radiation oncology, biology, physics, 2006, May-01, Volume: 65, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Biomarkers; Carbonic Anhydrase

2006
An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Administration, Oral; Animals; Colonic Neoplasms; DNA; Female; Humans; Idoxuridine; Liver; Liver Neo

1994
Kinetics of cell labeling and thymidine replacement after continuous infusion of halogenated pyrimidines in vivo.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Animals; Carcinoma; Cell Cycle; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Dose-Response Relations

1994
Colon-specific prodrugs of 5-radioiodo-2'-deoxyuridine.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:7

    Topics: Administration, Oral; Animals; beta-Galactosidase; beta-Glucosidase; Colonic Neoplasms; Digestive Sy

1996
Systematic heterogeneity and prognostic significance of cell proliferation in colorectal cancer.
    British journal of cancer, 1998, Volume: 77, Issue:6

    Topics: Cecal Neoplasms; Cell Division; Colonic Neoplasms; Colorectal Neoplasms; Female; Flow Cytometry; Hum

1998
In vivo modulation of iododeoxyuridine metabolism and incorporation into cellular DNA by 5'-amino-5'-deoxythymidine in normal mouse tissues and two human colon cancer xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:6

    Topics: Animals; Colonic Neoplasms; Dideoxynucleosides; DNA; Dose-Response Relationship, Drug; Female; HT29

1996
A new micromethod for the detection of HL-A antigens on cultured human tumor cells.
    Transplantation, 1975, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Antibody Specificity; Colonic Neoplasms; Culture Techniques; Cytotoxicity Tests, Imm

1975
An [125I]iododesoxyuridine utilization assay to measure the survival of human cells after various freezing programs.
    Cryobiology, 1979, Volume: 16, Issue:5

    Topics: Cell Survival; Colonic Neoplasms; DNA; Female; Freezing; Humans; Idoxuridine; Neoplasms; Ovarian Neo

1979
Simultaneous assessment of TGFB and cell cycle kinetics using IUdR/BrdU infusions in human neoplasms from plastic-embedded tissue.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1992, Volume: 40, Issue:3

    Topics: Antibodies, Monoclonal; Biopsy; Bone Marrow; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Coloni

1992
Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine.
    Radiation research, 1992, Volume: 131, Issue:1

    Topics: Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Radiation; Humans; Idoxuridine; In Vit

1992
Modulation of iododeoxyuridine-mediated radiosensitization by 5-fluorouracil in human colon cancer cells.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Cell Cycle; Colonic Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; In Vitro Techniques

1992
Fluorodeoxyuridine-mediated modulation of iododeoxyuridine incorporation and radiosensitization in human colon cancer cells in vitro and in vivo.
    Cancer research, 1991, Aug-01, Volume: 51, Issue:15

    Topics: Animals; Cell Cycle; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relatio

1991
Enhancement of metastatic potential by gamma-interferon.
    Cancer research, 1991, Aug-01, Volume: 51, Issue:15

    Topics: Adenocarcinoma; Animals; Antibodies; Cell Adhesion; Cell Division; Colonic Neoplasms; Extracellular

1991
The effect of radiosensitizers on radio-immunotherapy, using 131I-labelled anti-CEA antibodies in a human colonic xenograft model.
    International journal of cancer, 1991, Feb-20, Volume: 47, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Carcinoembryonic Antigen; Colonic Neoplasms; Humans; Idoxuridine; I

1991
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resi

1991
Tissue dose estimates following the selective uptake of 125IUdR and other radiolabelled thymidine precursors in resistant tumours.
    The British journal of radiology, 1991, Volume: 64, Issue:757

    Topics: Adenocarcinoma; Animals; Astatine; Bromine Radioisotopes; Cell Nucleus; Cell Survival; Choriocarcino

1991
Simultaneous immunohistochemical detection of IUdR and BrdU infused intravenously to cancer patients.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1991, Volume: 39, Issue:4

    Topics: Antibodies, Monoclonal; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Colonic Neoplasms; Humans; I

1991
Continuous infusion of halogenated pyrimidines.
    International journal of radiation oncology, biology, physics, 1991, Volume: 20, Issue:6

    Topics: Colonic Neoplasms; Combined Modality Therapy; Humans; Idoxuridine; In Vitro Techniques; Radiation-Se

1991
Incorporation of iododeoxyuridine into neoplastic DNA: a fraudulent magic bullet?
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:1

    Topics: Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Humans; Idoxuridine; Liver; Liver Neoplasms; Thymid

1990
The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells.
    Radiation research, 1990, Volume: 123, Issue:2

    Topics: Bromodeoxyuridine; Cell Line; Cell Survival; Colonic Neoplasms; DNA; DNA Damage; DNA, Neoplasm; DNA,

1990
Membrane-associated interleukin 1 alpha as a mediator of tumor cell killing by human blood monocytes fixed with paraformaldehyde.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cell Communication; Cell Line; Cell Membrane; Colonic Neoplasms;

1989
Stimulation of cells by antibody.
    Science (New York, N.Y.), 1973, Dec-28, Volume: 182, Issue:4119

    Topics: Animals; Antibodies, Neoplasm; Carcinoma; Cell Line; Colonic Neoplasms; Cross Reactions; DNA, Neopla

1973